Abstract:
:Maize leaves are divided into repeated longitudinal units consisting of vascular tissue, bundle sheath (BS), and mesophyll (M) cells. We have carried out a cell lineage analysis of these cell types using six spontaneous striping mutants of maize. We show that certain cell division patterns are preferentially utilized, but not required, to form the characteristic arrangement of cell types. Our data suggest that early in development a central cell layer is formed, most frequently by periclinal divisions in the adaxial subepidermal layer of the leaf primordium. Lateral and intermediate veins are initiated in this central layer, most often by divisions which contribute daughter cells to both the procambium and the ground meristem. These divisions generate "half vein" units which comprise half of the bundle sheath cells around a vein and a single adjacent M cell. We show that intermediate veins are multiclonal both in this transverse direction and along their lengths. BS cells are more closely related to M cells in the middle layer of the leaf than to those in the upper and lower subepidermal layers. An examination of sector boundaries has shown that photosynthetic differentiation in M cells is affected by the phenotype of neighboring BS cells.
journal_name
Dev Bioljournal_title
Developmental biologyauthors
Langdale JA,Lane B,Freeling M,Nelson Tdoi
10.1016/0012-1606(89)90304-7subject
Has Abstractpub_date
1989-05-01 00:00:00pages
128-39issue
1eissn
0012-1606issn
1095-564Xpii
0012-1606(89)90304-7journal_volume
133pub_type
杂志文章abstract::The elongation of embryo and tissue is a key morphogenetic event in embryogenesis and organogenesis. Notochord, a typical chordate organ, undergoes elongation to perform its regulatory roles and to form the structural support in the embryo. Notochord elongation is morphologically similar across all chordates, but asci...
journal_title:Developmental biology
pub_type: 杂志文章,评审
doi:10.1016/j.ydbio.2018.11.009
更新日期:2019-04-15 00:00:00
abstract::T-box family transcription factors play many roles in Metazoan development. Here we characterise Tbx6r, a unique Tbx6 paralogue isolated from the amphibian Xenopus. The evolution and developmental integration of this divergent T-box gene within the vertebrates reveals an unexpected level of plasticity within this cons...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2010.01.013
更新日期:2010-04-01 00:00:00
abstract::Notch pathway is crucial for stem/progenitor cell maintenance, growth and differentiation in a variety of tissues. Using a transgenic cell ablation approach, we found in our previous study that cells expressing Notch1 are crucial for prostate early development and re-growth. Here, we further define the role of Notch s...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2005.11.009
更新日期:2006-02-01 00:00:00
abstract::The expression of the neural cell adhesion molecules N-CAM and L1 was investigated in the olfactory system of the mouse using immunocytochemical and immunochemical techniques. In the olfactory epithelium, globose basal cells and olfactory neurons were stained by the polyclonal N-CAM antibody reacting with all three co...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(88)90397-1
更新日期:1988-10-01 00:00:00
abstract::Early mammalian embryogenesis is controlled by mechanisms governing the balance between pluripotency and differentiation. The expression of early lineage-specific genes can vary significantly between species, with implications for developmental control and stem cell derivation. However, the mechanisms involved in patt...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2012.12.008
更新日期:2013-03-01 00:00:00
abstract::The morphology of skeletal tissues formed in each of the branchial arches of higher vertebrates is unique. In addition to these structures, which are derived from the neural crest, the crest-derived connective tissues and mesodermal muscles also form different patterns in each of the branchial arches. The objective of...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(83)90318-4
更新日期:1983-03-01 00:00:00
abstract::The murine homeobox genes Msx-1 and Msx-2 are related to the Drosophila msh gene and are expressed in a variety of tissues during mouse embryogenesis. We now report the developmentally regulated expression of Msx-1 and Msx-2 in the mouse mammary gland and show that their expression patterns point toward significant fu...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1006/dbio.1996.0168
更新日期:1996-07-10 00:00:00
abstract::The embryonic chick face is composed of a series of facial primordia, epithelium-covered buds of mesenchyme, which surround the presumptive mouth. The protruding adult upper beak containing the prenasal cartilage is formed from the frontonasal mass, the paired maxillary primordia form the sides of the face, while the ...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(89)90142-5
更新日期:1989-11-01 00:00:00
abstract::Somatic embryogenesis is one of the best examples of the remarkable developmental plasticity of plants, in which committed somatic cells can dedifferentiate and acquire the ability to form an embryo and regenerate an entire plant. In Arabidopsis thaliana, the shoot apices of young seedlings have been reported as an al...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2018.04.023
更新日期:2018-10-01 00:00:00
abstract::During mouse fertilization the spermatozoon induces a series of low-frequency long-lasting Ca(2+) oscillations. It is generally accepted that these oscillations are due to Ca(2+) release through the inositol 1,4,5-trisphosphate (InsP(3)) receptor. However, InsP(3) microinjection does not mimic sperm-induced Ca(2+) osc...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1006/dbio.2000.9826
更新日期:2000-09-01 00:00:00
abstract::Genetic interactions regulating intermediate stages of tubulogenesis in the developing kidney have been difficult to define. A systems biology strategy using microarray was combined with in vitro/ex vivo and genetic approaches to identify pathways regulating specific stages of tubulogenesis. Analysis of the progressio...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2012.01.014
更新日期:2012-04-01 00:00:00
abstract::Retinoic acid (RA) signaling is required for normal development of multiple organs. However, little is known about how RA influences the initial stages of lung development. Here, we used a combination of genetic, pharmacological and explant culture approaches to address this issue, and to investigate how signaling by ...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2005.10.045
更新日期:2006-03-01 00:00:00
abstract::The definitive endoderm forms during gastrulation and is rapidly transformed into the gut tube which is divided along the anterior-posterior axis into the foregut, midgut, and hindgut. Lineage tracing and genetic analysis have examined the origin of the definitive endoderm during gastrulation and demonstrated that the...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2009.10.040
更新日期:2010-01-15 00:00:00
abstract::Dorsoventral specification of the zebrafish gastrula is governed by the functions of the dorsal shield, a region of the embryo functionally analogous to the amphibian Spemann organizer. We report that the bozozok locus encodes the transcription factor nieuwkoid/dharma, a homeobox gene with non-cell-autonomous organize...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1006/dbio.1999.9479
更新日期:1999-11-15 00:00:00
abstract::We have previously reported the detection of cAMP waves within monolayers of aggregating Dictyostelium discoideum cells (K. J. Tomchik and P.N. Devreotes, 1981, Science 212, 443-446). The computer-assisted analysis presented here of the fluorographic images of the cAMP waves reveals (1) all the waves have a consistent...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(83)90178-1
更新日期:1983-04-01 00:00:00
abstract::Catecholaminergic cells are transiently present during development of the fetal murine bowel. These transient catecholaminergic (TC) cells appear at Day E10, but by Day E13 can no longer be detected. In order to evaluate the hypothesis that these cells are the precursors of enteric neurons, we investigated the possibi...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(89)90217-0
更新日期:1989-03-01 00:00:00
abstract::Specification of the trophectoderm (TE) and inner cell mass (ICM) lineages in the mouse blastocyst correlates with cell position, as TE derives from outer cells whereas ICM from inner cells. Differences in position are reflected by cell polarization and Hippo signaling. Only in outer cells, the apical-basal cell polar...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2014.06.023
更新日期:2014-10-01 00:00:00
abstract::The unc-52 gene of Claenorhabditis elegans encodes a homologue of the basement membrane heparan sulfate proteoglycan perlecan. Viable alleles reduce the abundance of UNC-52 in late larval stages and increase the frequency of distal tip cell (DTC) migration defects caused by mutations disrupting the UNC-6/netrin guidan...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/s0012-1606(03)00014-9
更新日期:2003-04-01 00:00:00
abstract::During development of the vertebrate visual system, retinal ganglion cell (RGC) axons follow a precise path toward their midbrain targets. Although much is known about the cues that direct RGC axons once they have left the optic disc, less is known about the guidance of axons at earlier stages, when RGCs first send ou...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1006/dbio.1999.9312
更新日期:1999-07-01 00:00:00
abstract::N-cadherin is a Ca2+-dependent cell-cell adhesion molecule, which was identified in brain cells of mouse and chicken. In the present study, we have determined the pattern of expression of N-cadherin in chicken embryos at various stages by means of immunohistochemistry. N-cadherin was expressed in cells derived from al...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(87)90119-9
更新日期:1987-03-01 00:00:00
abstract::Voltage-gated Na(+) and K(+) channels are localized to distinct subcellular domains in mammalian myelinated nerve fibers. Specifically, Na(+) channels are clustered in high densities at nodes of Ranvier, while K(+) channels are found in juxtaparanodal zones just beyond regions of axoglial contact where sequential laye...
journal_title:Developmental biology
pub_type: 杂志文章,评审
doi:10.1006/dbio.2001.0326
更新日期:2001-08-01 00:00:00
abstract::The Drosophila Suppressor of Hairy wing [Su(Hw)] insulator protein has an essential role in the development of the female germline. Here we investigate the function of Su(Hw) in the ovary. We show that Su(Hw) is universally expressed in somatic cells, while germ cell expression is dynamic. Robust levels accumulate in ...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2011.05.666
更新日期:2011-08-15 00:00:00
abstract::Amphibian embryos from the genus Xenopus are among the best species for understanding early vertebrate development and for studying basic cell biological processes. Xenopus, and in particular the diploid Xenopus tropicalis, is also ideal for functional genomics. Understanding the behavior of genes in this accessible m...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2004.04.023
更新日期:2004-07-15 00:00:00
abstract::We have identified a cellular efflux pump, RhT, with the properties of an MDR transporter-a type of ATP-binding cassette transporter whose substrates include small hydrophobic molecules. RhT transports rhodamine 123 (Rh123) and is inhibited by low temperature, energy poisons, and several MDR transport inhibitors, such...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1006/dbio.2000.9611
更新日期:2000-04-01 00:00:00
abstract::The embryonic cell lineage of Caenorhabditis elegans has been traced from zygote to newly hatched larva, with the result that the entire cell lineage of this organism is now known. During embryogenesis 671 cells are generated; in the hermaphrodite 113 of these (in the male 111) undergo programmed death and the remaind...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(83)90201-4
更新日期:1983-11-01 00:00:00
abstract::The extent to which early differentiation of neurons and muscle cells is autonomous or governed by soluble factors released from other cells has been examined by following development of single cells plated alone in a simple, defined culture medium. The differentiation of electrical excitability and sensitivity to neu...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/0012-1606(86)90173-9
更新日期:1986-02-01 00:00:00
abstract::Defects in heart development are the most common congenital abnormalities in humans, providing a strong incentive to learn more about the underlying causes. Previous studies have implicated the metalloprotease-disintegrins ADAMs (a disintegrin and metalloprotease) 17 and 19 as well as heparin binding EGF-like growth f...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2005.05.004
更新日期:2005-07-15 00:00:00
abstract::The Id1 and Id3 genes play major roles during cardiac development, despite their expression being confined to non-myocardial layers (endocardium-endothelium-epicardium). We previously described that Id1Id3 double knockout (dKO) mouse embryos die at mid-gestation from multiple cardiac defects, but early lethality precl...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2010.10.004
更新日期:2011-01-01 00:00:00
abstract::Three-dimensional (3D) organoid models derived from human pluripotent stem cells provide a platform for studying human development and understanding disease mechanisms. Most studies that examine biallelic inactivation of the cell cycle regulator Retinoblastoma 1 (RB1) and the link to retinoblastoma is in mice, however...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/j.ydbio.2020.03.011
更新日期:2020-06-15 00:00:00
abstract::In this paper I sought to determine how the expression of differentiated traits of chick retinal pigmented epithelial (RPE) cells in vitro can be modulated by varying both the biochemical and the spatial complexity, and the mechanical properties, of the growth substratum. I have used glass derivatized with proteins of...
journal_title:Developmental biology
pub_type: 杂志文章
doi:10.1016/s0012-1606(89)80001-6
更新日期:1989-02-01 00:00:00