Abstract:
:Allergic rhinitis is often associated with asthma and has significant impacts on health care costs and productivity in the United States. Although allergen avoidance and pharmacotherapy are effective, allergen-specific immunotherapy is the only treatment that may lead to improved allergy symptoms even after treatment is discontinued. Subcutaneous immunotherapy has been the mainstay of allergen-specific immunotherapy in the United States for decades, but sublingual immunotherapy has recently become available. This review discusses the use of subcutaneous immunotherapy and sublingual immunotherapy in the treatment of allergic rhinitis and asthma and reviews the current evidence regarding the safety and efficacy of both formulations.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Roxbury CR,Lin SYdoi
10.1016/j.otc.2017.08.011subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1111-1119issue
6eissn
0030-6665issn
1557-8259pii
S0030-6665(17)30137-8journal_volume
50pub_type
杂志文章,评审abstract::This article provides guidelines for pharmacotherapy to maximize symptom relief from allergic rhinitis. Consideration of frequency, severity, and site of symptoms is important in directing pharmacotherapy efficacy and maximizing cost-effectiveness. The agents available include antihistamines, decongestants, steroids, ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(05)70032-3
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abstract::Successful management of the bony and cartilaginous dorsum requires accurate preoperative assessment and surgical planning. Careful management of the dorsum avoids most of the common pitfalls in rhinoplasty and contributes to patient satisfaction. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1987-11-01 00:00:00
abstract::The most common primary tumors of the frontal sinus are osteomas and inverted papillomas, although a variety of other tumors involving this space have been reported. With the advent of new surgical techniques and instrumentation, an endoscopic approach to this region has become feasible. The preoperative assessment an...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2016.03.026
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abstract::The treatment of patients with differentiated carcinoma of the thyroid is a controversial subject. This article discusses the authors' approach in the clinical practice. A description of the various types of papillary and follicular carcinoma is presented. Diagnostic tests, biologic behavior, and management are review...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-06-01 00:00:00
abstract::Sleep-related symptoms are extremely common in patients with allergic rhinitis. Sleep impairment is likely a major contributor to the overall disease morbidity, direct and indirect health care costs, and the loss of work productivity associated with allergic rhinitis. The association between allergic rhinitis and slee...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2011.03.020
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abstract::Microvascular free flaps have revolutionized the reconstruction of soft-tissue defects in the head and neck region in the last decade. In this article, the anatomy, surgical techniques, advantages, and disadvantages of a variety of flaps are discussed. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1994-02-01 00:00:00
abstract::Endoscopic endonasal approaches to the skull base pathology have developed and evolved dramatically over the past 2 decades, particularly with collaboration between neurosurgery and otolaryngology physicians. These advances have increased significantly the use of such approaches beyond just resection of pituitary aden...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2015.09.014
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2009.01.010
更新日期:2009-04-01 00:00:00
abstract::Voice-limiting pharyngoesophageal spasm presents a challenge to the surgeon who is trying to optimize functional voice outcomes in the laryngectomy patient. Modified closure techniques, adjunctive myotomy, and pharyngeal plexus neurectomy have the ability to improve or prevent pharyngoesophageal spasm. Attempts to max...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2004.01.005
更新日期:2004-06-01 00:00:00
abstract::The use of minimally invasive and endoscopic thyroidectomy techniques has become widespread. However, these procedures all result in a visible neck incision. Several remote access thyroidectomy approaches that place the necessary incision in inconspicuous, noncervical locations have recently been described. Robotic fa...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2014.02.001
更新日期:2014-06-01 00:00:00
abstract::Cross-sectional imaging plays an important role in the evaluation of the retropharyngeal space (RPS) and the prevertebral space (PVS). Because of their deep location within the neck, lesions arising within these spaces are difficult, if not impossible, to evaluate on clinical examination. This article details the cros...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2012.08.004
更新日期:2012-12-01 00:00:00
abstract::In summary, autogenous tissue remains the authors' preferred method of augmenting the nasal dorsum. Some authors have tried Supramid mesh, which tends to resorb. Mersilene seems to resist resorption and has been used with notable success. Silicone has had variable success but, because of bad publicity and the possibil...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-04-01 00:00:00
abstract::The management of base of tongue cancer has evolved steadily over time. Organ preservation with primary radiation therapy has produced excellent oncologic and functional outcomes. Concomitant chemotherapy has become important in patients with locoregionally advanced disease. Planned neck dissection after organ preserv...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2004.10.016
更新日期:2005-02-01 00:00:00
abstract::Partially implantable electromagnetic hearing aids have several potential advantages over conventional hearing aids. As conventional hearing aids improve in the quality of sound they deliver, however, the role of implant aids must be redefined. One area where they may provide the most benefit is in patients with moder...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-02-01 00:00:00
abstract::Advances in pediatric otology have provided new tools to diagnose and manage complex otologic disease. Diffusion-weighted MRI provides the surgeon with a tool to detect recurrent or residual cholesteatoma that may obviate a second look surgery. Surgical trends move toward less invasive surgery. The literature provides...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2019.05.003
更新日期:2019-10-01 00:00:00
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journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2004.10.001
更新日期:2005-04-01 00:00:00
abstract::Technological advancement in the operating room is evolving into a dynamic system mirroring that of the aeronautics industry. Through data visualization, information is continuously being captured, collected, and stored on a scalable informatics platform for rapid, intuitive, iterative learning. The authors believe th...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2017.01.016
更新日期:2017-06-01 00:00:00
abstract::With an unknown or occult primary cancer, the clinical presentation can be either undiagnosed lump or lumps in the neck that has been biopsied and diagnosed as metastatic cancer on the basis of the histopathologic findings. ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:
更新日期:1985-08-01 00:00:00
abstract::Patients with dizziness and psychopathology present diagnostic and therapeutic challenges to clinicians in several specialties. Clinical research is beginning to define the medical-psychiatric interactions that produce many of these patients' symptoms. Treatment research is still in its infancy. A model of illness pro...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(05)70230-9
更新日期:2000-06-01 00:00:00
abstract::The authors review problems associated with prolonged intubation. Laryngeal stenosis and injuries caused by the endotracheal tube itself are described. Postintubation laryngotracheal pathology, including signs and symptoms and the management of specific lesions, is described in detail. Other injuries associated with p...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00
abstract::Corticosteroids are widely used in otolaryngology to treat many disorders; however, the nature and extent of possible complications may not be completely understood. A comprehensive review of the physiology of systemic corticosteroids and literature discussing the known side effects associated with their use is presen...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2010.04.003
更新日期:2010-08-01 00:00:00
abstract::Surgical navigation technology provides real-time intraoperative localization of surgical instruments within the field. These systems are highly accurate, assist with preoperative planning, and improve surgeon confidence. The industry has recently responded to the growing trend of treatment in ambulatory surgical cent...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章
doi:10.1016/j.otc.2009.07.004
更新日期:2009-10-01 00:00:00
abstract::Petroclival meningiomas are most commonly found in women around 50 years of age and have the general tendency to grow and affect several cranial nerves. At presentation, many patients complain of headaches, gait disturbances and cranial neuropathies. Treatment options include surgery, with a variety of surgical approa...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2015.02.007
更新日期:2015-06-01 00:00:00
abstract::Mechanical endonasal dacryocystorhinostomy (DCR) involves the creation of a large rhinostomy and the preservation of lacrimal and nasal mucosa. It replicates the main advantages of the external approach to DCR using minimally invasive techniques. A thorough knowledge of intranasal anatomy and the close collaboration o...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2006.07.007
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abstract::This article provides a concise review of contemporary options for evaluating voice disorders. Focus is given to patient history and patient-derived voice handicap and quality of life assessments, clinician-derived perceptual analysis of voice, and finally flexible and rigid, high-definition laryngoscopy with videostr...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2019.03.002
更新日期:2019-08-01 00:00:00
abstract::Facial nerve paralysis in children should be considered distinct from that which occurs in adults. The author submits a slightly different classification of facial nerve paralysis in children based on traditional thinking. Specifically, acquired facial nerve paralysis is thought to be influenced by both prenatal and p...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-06-01 00:00:00
abstract::Wegener's granulomatosis is an idiopathic, granulomatous disease with the potential for multiple head and neck manifestations. The otolarygologist is an essential part of the multidisciplinary team involved in establishing the diagnosis and providing ongoing care for patients with Wegener's granulomatosis. Diagnostic ...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0030-6665(03)00023-9
更新日期:2003-08-01 00:00:00
abstract::Chronic ear disease is a major cause of acquired hearing loss in the developing world. It is prevalent on every continent, but occurs more commonly in poorer nations owing to a lack of preventative measures. This article outlines the particular challenges in treating this disease in the developing world, including a d...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.otc.2018.01.017
更新日期:2018-06-01 00:00:00
abstract::This article outlines the historical development of the use of lasers in the tracheobronchial tree, the current indications for the use of carbon dioxide and neodymium:yttrium-aluminum-garnet lasers, and the management of complications. The merits of other laser wavelengths are mentioned, including use of the potassiu...
journal_title:Otolaryngologic clinics of North America
pub_type: 历史文章,杂志文章,评审
doi:
更新日期:1996-12-01 00:00:00
abstract::Benign paroxysmal positional vertigo is a common condition that can be severely incapacitating. The causative mechanism is usually displaced dense particles (canaliths) in a semicircular canal. By means of canalith repositioning, these particles can be moved into the utricle and the symptoms completely resolved in a h...
journal_title:Otolaryngologic clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1996-04-01 00:00:00