Hydroxyurea therapy in adult Nigerian sickle cell disease: a monocentric survey on pattern of use, clinical effects and patient's compliance.

abstract：BACKGROUND:The morbid effects of urinary bilharziasis are becoming more evident with the advent of sophisticated diagnostics such as ultrasound. However, such diagnosis of Schistosoma haematobium morbidity is often hampered by lack of funds, proper equipment, or training. OBJECTIVE:We performed a cross-sectional inves...

journal_title：African health sciences

authors： Brouwer KC,Munatsi A,Ndhlovu PD,Wagatsuma Y,Shiff CJ

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:It has been shown that colorectal carcinoma is increasing in incidence in African countries. This could be due to change in life style. Molecular pathogenesis of colorectal cancer commonly involves mutation in p53 gene which leads to expression of p53 protein in tumor cells. Expression of p53 protein has bee...

journal_title：African health sciences

authors： Rambau PF,Odida M,Wabinga H

更新日期：2008-12-01 00:00:00

abstract：Introduction:Chronic pain classification in HIV positive patients is essential for diagnosis and treatment. However, this is rarely done despite association with poor outcomes. Methods:A cross-sectional survey of 345 consented patients at a specialized HIV care center in Uganda was conducted. Chronic pain was defined ...

journal_title：African health sciences

authors： Mwesiga EK,Kaddumukasa M,Mugenyi L,Nakasujja N

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Malaria is on the increase due to emergence of parasite drug resistance and there is thus an urgent need for the development of new antiparasitic drugs effective at low concentrations. Ketolides antibiotics are used for treatment of various ailments and are relevant candidates to establish antiparasitic acti...

journal_title：African health sciences

authors： Makgatho M,Maimela E,Mbajiorgu F

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Optimal management of asthma in resource limited settings is hindered by lack of resources, making it difficult for health providers to adhere to international guidelines. The purpose of this review is to identify steps for asthma diagnosis and management in resource limited settings. METHODS:Review of inte...

journal_title：African health sciences

authors： Kirenga BJ,Schwartz JI,de Jong C,van der Molen T,Okot-Nwang M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Human Immunodeficiency virus (HIV) and Hepatitis C virus (HCV) are both major global health concerns as they cause high mortality and morbidity in the developing countries. However, while data exists for the co-infection in other countries, little or no information can be found with regard to the sero-preval...

journal_title：African health sciences

authors： Duru MU,Aluyi HS,Anukam KC

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Upper gastrointestinal bleeding (UGIB) is a common emergency medical condition that may require hospitalization and resuscitation, and results in high patient morbidity. Upper gastrointestinal endoscopy is the preferred investigative procedure for UGIB because of its accuracy, low rate of complication, and i...

journal_title：African health sciences

authors： Alema ON,Martin DO,Okello TR

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Tuberculosis is one of the causes of granulomatous disease within the anorectal region. The clinical features, which include symptoms and signs of anal pain or discharge, multiple or recurrent fistula in ano and inguinal lymphadinopathy, are not characteristically distinct from other anal lesions. It is also...

journal_title：African health sciences

authors： Gupta PJ

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Illicit use of high dosage buprenorphine has been well documented in several countries, including Tunisia. OBJECTIVES:The aim of this survey is to assess the buprenorphine withdrawal syndrome time course, and how it may be affected by the population characteristics among subjects admitted to a rehabilitatio...

journal_title：African health sciences

authors： Derbel I,Ghorbel A,Akrout FM,Zahaf A

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:South Africa has endorsed a World Health Assembly (WHA) resolution calling for control of soil-transmitted helminths (STHs). In Cape Town, services and housing that exist in old-established suburbs should minimise the prevalence of intestinal parasitic infections, even when residents are poor. Where families...

journal_title：African health sciences

authors： Adams VJ,Markus MB,Adams JF,Jordaan E,Curtis B,Dhansay MA,Obihara CC,Fincham JE

更新日期：2005-06-01 00:00:00

abstract：BACKGROUND:The impact and management of HIV/AIDS in Lesotho in the context of disaster management was investigated. OBJECTIVES:Lesotho health care workers' perception on HIV/AIDS progression, whether HIV/AIDS was managed as a disaster, and the impact on the demographic profile was investigated. METHODS:The empirical ...

journal_title：African health sciences

authors： Belle JA,Ferriera SB,Jordaan A

更新日期：2013-12-01 00:00:00

abstract：Background:The staphylococci have increasingly been associated with infections worldwide and anti-microbial resistance has made these versatile pathogens more recalcitrant in the hospital setting. Objectives:This study sought to investigate the occurrence and distribution of Staphylococcus species as well as determine...

journal_title：African health sciences

authors： Ibadin EE,Enabulele IO,Muinah F

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:All research involving human participants should be reviewed by a competent and independent institutional research and ethics committee. Research conducted at Makerere University College of Health Sciences should be subjected to a rigorous review process by the ethics committee in order to protect human part...

journal_title：African health sciences

authors： Ibingira BR,Ochieng J

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:The Democratic Republic of Congo (DRC) is a developing country with poor obstetric indicators. Despite ongoing efforts to improve care, women continue to suffer multiple complications of child birth including vesico-vaginal fistulae (VVF). OBJECTIVE:To describe socio-demographic and clinical characteristics...

journal_title：African health sciences

authors： Paluku JL,Carter TE

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:The diagnosis of tuberculosis in children is difficult particularly in HIV infected children. The poor outcome following antituberculosis treatment usually reported in HIV infected children might be due, in part, to other HIV-related chronic diseases wrongly diagnosed as TB. OBJECTIVE:The study examines the...

journal_title：African health sciences

authors： Kiwanuka JP

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the antimicrobial activity of Momordica charantia extracts on reference strains and microorganisms isolated from clinical specimens. METHOD:Petroleum ether and methanolic crude extracts of fruits and leaves of the plant were evaluated for antimicrobial activity using the disk diffusion method on ...

journal_title：African health sciences

authors： Mwambete KD

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Drug related problem (DRPs) is a key factor which will affect the outcome of therapy and safety. OBJECTIVE:To assess the DRPs in type 2 diabetes mellitus (T2DM) patients and psychological aspects of patients by community pharmacists to observe the rate of DRP. METHODS:Prospective randomized controlled inte...

journal_title：African health sciences

authors： Gangwar SS,Monisha N,Nachiya J,Narasingarao K,Parimalakrishnan S,Singh SP

更新日期：2014-09-01 00:00:00

abstract：Background:Rape remains a controversial issue with a few victims reporting experience because of the myriad of societal perception, prolonged steps in pursuing a case to logical conclusion of securing conviction, as well as psychological and physical residuals of the experience. Data in Nigeria is therefore hard to com...

journal_title：African health sciences

authors： Idoko CA,Nwobodo E,Idoko CI

更新日期：2020-06-01 00:00:00

abstract：Background:Variceal upper gastrointestinal bleeding (UGIB) is common in sub-Saharan Africa (SSA). However, poor access to endoscopy services precludes the diagnosis of varices. Objectives:We determined the diagnostic accuracy of routine clinical findings for detection of esophageal varices among patients with UGIB in ...

journal_title：African health sciences

authors： Opio CK,Rejani L,Kazibwe F,Ocama P

更新日期：2019-12-01 00:00:00

abstract：Background:Elabela (ELA) is a hormone that is secreted at high levels in the kidneys of a healthy adult. This study aims to investigate whether serum ELA levels of patients with Type 2 Diabetes vary with the severity of renal damage. Methods:Our study included 50 healthy control subjects and 100 diabetic patients, who...

journal_title：African health sciences

authors： Onalan E,Doğan Y,Onalan E,Gozel N,Buran I,Donder E

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Pain, swelling and trismus are common complications associated with third molar surgery. These complications have been reported to have an adverse effect on the quality of life of patients undergoing third molar surgery. OBJECTIVE:To review the different modalities of minimizing inflammatory complications i...

journal_title：African health sciences

authors： Osunde OD,Adebola RA,Omeje UK

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Patients with stroke experience a number of environmental barriers, limiting their re-integration. Information regarding the barriers experienced by patients with stroke in a specific setting such as the Musanze district in Rwanda would assist with the development of rehabilitation programmes that would take...

journal_title：African health sciences

authors： Urimubenshi G,Rhoda A

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:HIV/AIDS is a major public health problem in Cameroon which had a prevalence of 5.1% in 2010 with 141 new infections per day. The fear of voluntary counseling and testing (VCT) is an obstacle to HIV prevention. OBJECTIVES:To determine the prevalence of HIV-1, HIV-2 and HIV-1/HIV-2 co-infection among people ...

journal_title：African health sciences

authors： Nsagha DS,Njunda AL,Kamga HL,Assob JC,Bongkem EA

更新日期：2012-09-01 00:00:00

abstract：Background:Depression is a common illness worldwide with high rate among medical students. The objectives were to estimate the prevalence of depression among medical students in Alexandria, and identify its correlates. Methods:A cross-sectional study design was used. The study was conducted at the Faculty of Medicine,...

journal_title：African health sciences

authors： Elsawy WIH,Sherif AAR,Attia MSED,El-Nimr NA

更新日期：2020-09-01 00:00:00

abstract：Background:Propofol is administered as intermittent boluses to achieve deep sedation to facilitate oesophagogastroduodenoscopy. Target controlled infusion (TCI) can be employed for this purpose. Methods:176 adults were randomly allocated into two groups of 88 patients. Control group: Received an initial bolus of propo...

journal_title：African health sciences

authors： Ndosi C,Mung'ayi V,Gisore E,Mir S

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The principal mode of HIV transmission in Southern Africa is through sexual intercourse, and this has prompted uptake of safe male circumcision. Engaging in risky sexual behaviour by circumcised men increases the risks of acquiring HIV, though male circumcision coupled with preventive behaviour reduces this ...

journal_title：African health sciences

authors： Balekang GB,Dintwa KF

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Little information is available on the rapid diagnostic testing for syphilis in Burkina Faso. The objectives of the study were (i) to assess the sensitivity and specificity of four on site rapid tests in comparison with Treponema pallidum haemagglutination assay (TPHA) as a gold standard and (i...

journal_title：African health sciences

authors： Bocoum FY,Ouédraogo H,Tarnagda G,Kiba A,Tiendrebeogo S,Bationo F,Liestman B,Diagbouga S,Zarowsky C,Traoré RO,Kouanda S

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Day case surgery services are increasing all over the world. The prevalence of postoperative pain after day surgery is found to be high. Little is known about the prevalence of postoperative pain, in Kenya, after day case surgeries. OBJECTIVE:To investigate the prevalence of postoperative pain after day sur...

journal_title：African health sciences

authors： Mwaka G,Thikra S,Mung'ayi V

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Many developing countries increasingly recognize and acknowledge family planning as a critical part of socio-economic development. However, with few health dollars to go around, countries tend to provide essential drugs for curative care, rather than for family planning products. Donors have historically pro...

journal_title：African health sciences

authors： Chandani Y,Breton G

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Morbid obesity of parturient has become very important in perinatal medicine because of a worldwide obesity epidemic. Morbid obesity of parturient is reportedly associated with severely increased anaesthetic and obstetric risk. OBJECTIVE:To determine the prevalence rate, anaesthetic and obstetric complicati...

journal_title：African health sciences

authors： Okafor UV,Efetie ER,Nwoke O,Okezie O,Umeh U

更新日期：2012-03-01 00:00:00