Effects of Psychotropic Drugs on Seizure Threshold during Electroconvulsive Therapy.

Abstract:

OBJECTIVE:To analyze the relationship between seizure threshold (ST) and psychotropic drugs in patients treated with ECT. METHODS:We examined clinical data from 43 patients. ST was titrated at each treatment session. We examined associations between ST and psychotropic drugs using multivariate correlation analyses. Data are presented as initial ST, the difference in ST between the first and 10th sessions (ΔST10th), and the mean difference in ST between the first and last sessions (mean ΔSTlast). RESULTS:Multivariate regression analyses showed associations between initial ST and the total chlorpromazine-equivalent dose of antipsychotics (β=0.363, p<0.05). The total fluoxetine-equivalent dose of antidepressants was associated with ΔST10th (β=0.486, p<0.01) and mean ΔSTlast (β=0.472, p<0.01). CONCLUSION:Our study elucidated possible effects of psychotropic drugs on ST shifts. Larger doses of antipsychotics were associated with higher initial ST, whereas higher doses of antidepressants were associated with stronger shifts in ST.

journal_name

Psychiatry Investig

journal_title

Psychiatry investigation

authors

Chi SH,Jeong HG,Lee S,Oh SY,Kim SH

doi

10.4306/pi.2017.14.5.647

subject

Has Abstract

pub_date

2017-09-01 00:00:00

pages

647-655

issue

5

eissn

1738-3684

issn

1976-3026

journal_volume

14

pub_type

杂志文章
  • Electroconvulsive therapy on severe obsessive-compulsive disorder comorbid depressive symptoms.

    abstract::Electroconvulsive therapy (ECT) is not currently used as a first-line treatment for obsessive-compulsive disorder (OCD). However, several related case reports have demonstrated that ECT seems to be effective for severe OCD, especially when first-line therapies have failed. In this study, we describe the courses, detai...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2014.11.2.210

    authors: Liu X,Cui H,Wei Q,Wang Y,Wang K,Wang C,Zhu C,Xie X

    更新日期:2014-04-01 00:00:00

  • Linking an Anxiety-Related Personality Trait to Cardiac Autonomic Regulation in Well-Defined Healthy Adults: Harm Avoidance and Resting Heart Rate Variability.

    abstract:OBJECTIVE:Anxiety trait, anxiety and depression states have all been reported to increase risks for cardiovascular disease (CVD), possibly through altering cardiac autonomic regulation. Our aim was to investigate whether the relationship between harm avoidance (HA, an anxiety-related personality trait) and cardiac auto...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2016.13.4.397

    authors: Kao LC,Liu YW,Tzeng NS,Kuo TB,Huang SY,Chang CC,Chang HA

    更新日期:2016-07-01 00:00:00

  • Association of the Catechol O-Methyltransferase Val158-Met Polymorphism and Reduced Interference Control in Korean Children with Attention-Deficit Hyperactivity Disorder.

    abstract:OBJECTIVE:We tested for association of the catechol-O-methyltransferase (COMT) Val(158)-Met (rs4680) polymorphism with attention-deficit hyperactivity disorder (ADHD) using family-based test in Korean trios. METHODS:A total of 181 subjects with ADHD along with both of their biological parents were recruited from Unive...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2015.12.4.563

    authors: Park S,Park JE,Yoo HJ,Kim JW,Cheong JH,Han DH,Kim Y,Kim BN

    更新日期:2015-10-01 00:00:00

  • Standardization Study of the Korean Version of the Stages of Change Readiness and Treatment Eagerness Scale for Smoking Cessation (K-SOCRATES-S) and Its Predictive Validity.

    abstract:OBJECTIVE:The purpose of the study was to develop the Korean version of the Stage of Change Readiness and Treatment Eagerness Scale for Smoking Cessation (K-SOCRATES-S) based on the Korean version of the Stages of Readiness for Change and Eagerness for Treatment scale (K-SOCRATES). This paper also demonstrates its reli...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2012.9.3.223

    authors: Park JW,Park KH,Joe KH,Choi SH,Lee IJ,Hwang JH,Kwon M,Wang SM,Kim DJ

    更新日期:2012-09-01 00:00:00

  • Associations of Temperament and Character with Coping Strategies among Office Workers.

    abstract:OBJECTIVE:Coping can be defined as the reactions to harm or distress individuals take to reduce stress. This study aimed to determine how an individual's temperament and character is correlated with the person's main coping method. METHODS:The Korean version of the Ways of Coping Questionnaire and Temperament and Char...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.0084

    authors: Hwang HC,Kim SM,Han DH,Min KJ

    更新日期:2020-01-01 00:00:00

  • Prevalence and correlates of problematic internet experiences and computer-using time: a two-year longitudinal study in korean school children.

    abstract:OBJECTIVE:To measure the prevalence of and factors associated with online inappropriate sexual exposure, cyber-bullying victimisation, and computer-using time in early adolescence. METHODS:A two-year, prospective school survey was performed with 1,173 children aged 13 at baseline. Data collected included demographic f...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2014.11.1.24

    authors: Yang SJ,Stewart R,Lee JY,Kim JM,Kim SW,Shin IS,Yoon JS

    更新日期:2014-01-01 00:00:00

  • Combined Measures of Psychomotor and Cognitive Alterations as a Potential Hallmark for Bipolar Depression.

    abstract:OBJECTIVE:The current study aimed to examine whether specific features of psychomotor retardation (PMR) and cognitive functioning established different profiles in unipolar (UD) and bipolar depression (BD). METHODS:Two groups of age-matched patients with UD (n=54) and BD (n=20) completed the Montgomery-Asberg Depressi...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.0116

    authors: Robin A,Sauvaget A,Deschamps T,Bulteau S,Thomas-Ollivier V

    更新日期:2019-12-01 00:00:00

  • Age-Related Changes in Auditory Nogo-N200 Latency in Medication-Naïve Children and Adolescents with Attention-Deficit/Hyperactivity Disorder.

    abstract:OBJECTIVE:Event-related potential (ERP) changes with brain development in healthy children and adolescents. However, few studies have focused on age-related changes in the N200 and P300 components among individuals with attention-deficit/hyperactivity disorder (ADHD). Therefore, this study aimed to assess age-related d...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2020.0083

    authors: Lee YJ,Jeong MY,Park S,Kim JH,Kim JS,Woo SI

    更新日期:2020-07-01 00:00:00

  • Frontal Lobe Dysfunction in a Depressed Patient Who Survived a Suicide Attempt by Jumping from the Bridge on the Han River.

    abstract::Suicide attempts at the Han river are rapidly increasing, which are 4.11 times from 2005 to 2015, whereas the rate of completed suicide in South Korea increased 1.07 times during the same period. However, few studies have been conducted on the issue because many suicide attempters were seriously injured after a fall i...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2017.14.6.904

    authors: Kim K,Jeon HJ

    更新日期:2017-11-01 00:00:00

  • Bipolar and Related Disorders Induced by Sodium 4-Phenylbutyrate in a Male Adolescent with Bile Salt Export Pump Deficiency Disease.

    abstract::Bile Salt Export Pump (BSEP) Deficiency disease, including Progressive Familial Intrahepatic Cholestasis type 2 (PFIC2), is a rare disease, usually leading within the first ten years to portal hypertension, liver failure, hepatocellular carcinoma. Often liver transplantation is needed. Sodium 4-phenylbutyrate (4-PB) s...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2016.13.5.580

    authors: Vitale G,Simonetti G,Pirillo M,Taruschio G,Andreone P

    更新日期:2016-09-01 00:00:00

  • Disruption of orbitofronto-striatal functional connectivity underlies maladaptive persistent behaviors in alcohol-dependent patients.

    abstract:OBJECTIVE:Alcohol dependence is characterized by persistent alcohol-seeking despite negative consequences. Previous studies suggest that maladaptive persistent behaviors reflect alcohol-induced brain changes that cause alterations in the cortico-striatal-limbic circuit. METHODS:Twenty one alcohol dependent patients an...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.3.266

    authors: Lee S,Lee E,Ku J,Yoon KJ,Namkoong K,Jung YC

    更新日期:2013-09-01 00:00:00

  • Distinguishing Quantitative Electroencephalogram Findings between Adjustment Disorder and Major Depressive Disorder.

    abstract:OBJECTIVE:Adjustment disorder (ADJ) is a common diagnosis. However, it is difficult to distinguish ADJ from other major Axis I disorders, such as major depressive disorder (MDD). The aim of this study was to determine the distinguishing neurophysiological characteristics between ADJ and MDD using quantitative analysis ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.1.62

    authors: Jeong HG,Ko YH,Han C,Kim YK,Joe SH

    更新日期:2013-03-01 00:00:00

  • Traumatic experiences and mental health of north korean refugees in South Korea.

    abstract:OBJECTIVE:This study was conducted at Hanawon-a government sponsored educational facility for the settlement of North Korean refugees during their initial phase in South Korea-in 2004 to explore their mental health status and traumatic experiences in North Korea and during their escape period. METHODS:A survey was con...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2008.5.4.213

    authors: Jeon WT,Yu SE,Cho YA,Eom JS

    更新日期:2008-12-01 00:00:00

  • Association of G-Protein β3 Subunit C825T Polymorphism with Seasonal Variations in Mood and Behavior.

    abstract:OBJECTIVE:Seasonal affective disorder and seasonal changes in mood and behavior are associated with several genes that regulate circadian rhythms. In this study, we investigated the relationship between the C825T polymorphism of the G-protein β3 subunit and seasonal variations in mood and behavior in a young healthy Ko...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2017.09.21

    authors: Nam YJ,Cho CH,Kim L,Lee HJ

    更新日期:2018-02-01 00:00:00

  • Clinical, Psychopathological, Physical, and Sleep Evolution in Adolescents with Restrictive Anorexia Nervosa Participating in a Day Hospital Program.

    abstract:OBJECTIVE:To analyze the clinical, psychopathological, physical, and sleep-related evolution of adolescents with restricting-type of anorexia nervosa (AN-R) after 10 weeks of a daytime hospital program. METHODS:Body composition, physical activity and sleep were measured objectively before and after 10 weeks of treatme...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2020.0016

    authors: Martínez-Sánchez SM,Martínez-García TE,Munguía-Izquierdo D

    更新日期:2020-04-01 00:00:00

  • Structural MRI and Amyloid PET Imaging for Prediction of Conversion to Alzheimer's Disease in Patients with Mild Cognitive Impairment: A Meta-Analysis.

    abstract:OBJECTIVE:The aim of this study was to explore the prognostic values of biomarkers of neurodegeneration as measured by magnetic resonance imaging (MRI) and amyloid burden as measured by amyloid positron emission tomography (PET) in predicting conversion to Alzheimer's disease (AD) in patients with mild cognitive impair...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2017.14.2.205

    authors: Seo EH,Park WY,Choo IH

    更新日期:2017-03-01 00:00:00

  • The temperament and character of korean male conscripts with military maladjustment-a preliminary study.

    abstract:OBJECTIVE:Recently, an increasing number of Korean male conscripts have been retiring because of military maladjustment despite the presence of qualifying medical and psychological screening tests in the Korean army. These problems suggest the presence of a common personality problem. To further examine this possibilit...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2013.10.2.131

    authors: Han KH,Lee SB

    更新日期:2013-06-01 00:00:00

  • Brain-Derived Neurotrophic Factor Gene Val66Met Polymorphism Is a Risk Factor for Attention-Deficit Hyperactivity Disorder in a Turkish Sample.

    abstract:OBJECTIVE:Attention-deficit hyperactivity disorder (ADHD) is a neurodevelopmental disorder that negatively affects different areas of life. We aimed to evaluate the associations between the Val66Met polymorphism of brain-derived neurotrophic factor (BDNF) and ADHD and to assess the effect of the BDNF polymorphism on th...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2016.13.5.518

    authors: Ozturk O,Basay BK,Buber A,Basay O,Alacam H,Bacanlı A,Yılmaz ŞG,Erdal ME,Herken H,Ercan ES

    更新日期:2016-09-01 00:00:00

  • The Association between Physical Activity and Anxiety Symptoms for General Adult Populations: An Analysis of the Dose-Response Relationship.

    abstract:OBJECTIVE:The aim of this study is to determine the dose-response relationship between physical activity and anxiety symptoms. METHODS:We included data of 124,434 participants who had comprehensive health-screening examinations from January 1st, 2012, to December 31st, 2016, in Kangbuk Samsung Hospital, Seoul and Suwo...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.0078

    authors: Kim SY,Jeon SW,Lee MY,Shin DW,Lim WJ,Shin YC,Oh KS

    更新日期:2020-01-01 00:00:00

  • Prevalence and risk factors associated with suicide ideation and attempts in korean college students.

    abstract:OBJECTIVE:Suicide is a leading cause of death in college age students. Identification of the associated risk factors has important implications for how to prevent and respond to this population; however, few studies have been performed on this topic in this age group. The purpose of this study was to evaluate the preva...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2008.5.2.86

    authors: Lee HS,Kim S,Choi I,Lee KU

    更新日期:2008-06-01 00:00:00

  • Serum homocysteine and folate levels in korean schizophrenic patients.

    abstract:OBJECTIVE:This study was conducted to confirm the results of the authors' previous research on schizophrenia manifesting high serum homocysteine and low folate levels. This study is anchored on a theory that a high serum homocysteine concentration affects schizophrenia by virtue of a neurotoxic mechanism, and on a repo...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2011.8.2.134

    authors: Kim TH,Moon SW

    更新日期:2011-06-01 00:00:00

  • Development of a Biomarker-Based Diagnostic Algorithm for Posttraumatic Syndrome after Physical Injury: Design of the BioPTS Study.

    abstract::Severe physical injury is a leading cause of posttraumatic syndrome (PTS). This is to develop a biomarker-based diagnostic algorithm for posttraumatic syndrome (BioPTS) study. This is a 2-year longitudinal cohort study assessing patients who were hospitalized beginning in 2015 at Chonnam National University Hospital i...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2017.14.4.513

    authors: Kim JW,Kang HJ,Bae KY,Kim SW,Oh HK,Kim MG,Kim JM

    更新日期:2017-07-01 00:00:00

  • The Symptom Frequency Characteristics of the Hamilton Depression Rating Scale and Possible Symptom Clusters of Depressive Disorders in Korea: The CRESCEND Study.

    abstract:OBJECTIVE:This study analyzed the symptom frequencies of 17-item Hamilton Depression Rating Scale (HDRS-17) to understand the characteristics of each item and to propose the possible symptoms clusters. METHODS:From psychiatric clinics of 18 Hospitals in Korea, 1,183 patients, diagnosed with major depressive disorder (...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2011.8.4.312

    authors: Jang SH,Park YN,Jae YM,Jun TY,Lee MS,Kim JM,Jeong SH,Kim JB

    更新日期:2011-12-01 00:00:00

  • Reliability and Validity of a Turkish Version of the Acceptance and Action Diabetes Questionnaire.

    abstract:OBJECTIVE:The aim of this study is to perform validity and reliability examination of the Turkish form of Acceptance and Action Diabetes Questionnaire, and to investigate whether this scale is a measurement tool for evaluation of psychological flexibility levels in a sample of patients with diabetes in Turkey. METHODS...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.02.26.2

    authors: Karadere ME,Yavuz KF,Asafov EY,Küçükler FK

    更新日期:2019-06-01 00:00:00

  • Psychometric Properties of a Short Korean Version of the Revised Obsessive Intrusion Inventory.

    abstract:OBJECTIVE:The Revised Obsessive Intrusion Inventory (ROII) is a 52-item scale that evaluates obsessional intrusive thoughts. The aim of the present study was to validate a short, 20-item Korean version of the ROII (ROII-20). METHODS:Of the 1125 participants who completed the ROII-20, 895 participants completed the sca...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2015.12.3.288

    authors: Seo JW,Baek MJ,Lee MS,Jeon JR,Kwon SM

    更新日期:2015-07-01 00:00:00

  • The Association between Depressive Mood and Cholesterol Levels in Korean Adolescents.

    abstract:OBJECTIVE:Previous studies have shown that there is a correlation between lipid levels and depressive mood, and that lipids could be useful biomarkers for depression. We conducted this study to clarify the association between lipid levels and depressive mood in adolescents, especially in community samples. METHODS:We ...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.03.24

    authors: Kim EJ,Hong J,Hwang JW

    更新日期:2019-10-01 00:00:00

  • Evaluation of Oxidative Metabolism in Child and Adolescent Patients with Attention Deficit Hyperactivity Disorder.

    abstract:OBJECTIVE:Oxidative metabolism is impaired in several medical conditions including psychiatric disorders, and this imbalance may be involved in the etiology of these diseases. The present study evaluated oxidative balance in pediatric and adolescent patients with attention deficit hyperactivity disorder (ADHD). METHOD...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2015.12.3.361

    authors: Kul M,Unal F,Kandemir H,Sarkarati B,Kilinc K,Kandemir SB

    更新日期:2015-07-01 00:00:00

  • Psychometric properties of the life events checklist-korean version.

    abstract:OBJECTIVE:The Life Events Checklist is a brief screening instrument that is used for potentially traumatic events such as accidents, disasters, sexual or physical assaults, or combat-related exposures. The original English version was recently tested for reliability and validity and it showed good psychometric properti...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2008.5.3.163

    authors: Bae H,Kim D,Koh H,Kim Y,Park JS

    更新日期:2008-09-01 00:00:00

  • Benzodiazepine-Related Cognitive Impairment or Dementia: A Signal Detection Study Using a Case/Non-Case Approach.

    abstract:OBJECTIVE:The association between benzodiazepine use and the risk of cognitive impairment or dementia has been controversial. Our study aims to detect this association through a case/non-case method using the Korea Institute of Drug Safety & Risk Management-Korea adverse event reporting system database (KIDS-KD) betwee...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.30773/pi.2019.0275

    authors: Baek YH,Kim HJ,Bae JH,Lee H,Oh IS,Kim WJ,Shin JY

    更新日期:2020-06-01 00:00:00

  • Relationship between Childhood Maltreatment, Suicidality, and Bipolarity: A Retrospective Study.

    abstract:OBJECTIVE:The aims of current study were to determine whether childhood maltreatment contributes to the occurrence of major depressive disorder (MDD) with bipolarity or suicidality. METHODS:In total, 132 outpatients diagnosed with MDD between 2014 and 2015 on the medical records were included. The subjects were divide...

    journal_title:Psychiatry investigation

    pub_type: 杂志文章

    doi:10.4306/pi.2017.14.2.136

    authors: Park YM

    更新日期:2017-03-01 00:00:00