Comparative Connectomics.

Abstract:

:We introduce comparative connectomics, the quantitative study of cross-species commonalities and variations in brain network topology that aims to discover general principles of network architecture of nervous systems and the identification of species-specific features of brain connectivity. By comparing connectomes derived from simple to more advanced species, we identify two conserved themes of wiring: the tendency to organize network topology into communities that serve specialized functionality and the general drive to enable high topological integration by means of investment of neural resources in short communication paths, hubs, and rich clubs. Within the space of wiring possibilities that conform to these common principles, we argue that differences in connectome organization between closely related species support adaptations in cognition and behavior.

journal_name

Trends Cogn Sci

authors

van den Heuvel MP,Bullmore ET,Sporns O

doi

10.1016/j.tics.2016.03.001

subject

Has Abstract

pub_date

2016-05-01 00:00:00

pages

345-361

issue

5

eissn

1364-6613

issn

1879-307X

pii

S1364-6613(16)00048-6

journal_volume

20

pub_type

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