Abstract：
STUDY DESIGN:Retrospective cohort analysis with prospective follow-up. OBJECTIVES:To evaluate neurological and functional recovery following central cord syndrome. SETTING:Northern Ireland, population 1.8 million. METHODS:Twenty-seven cords were identified in 1 year. Five managed conservatively and 22 with surgery. American Spinal Injury Association (ASIA) motor scores (AMS) were calculated to assess neurological recovery. Rotterdam scores assessed functional independence at 3 years. RESULTS:Average age was 62 years. Mechanism of injury was a fall with neck hyperextension in 81% patients. Average AMS in surgical patients improved from injury, preoperatively, postoperatively, 6 months and 3 years from 51, 81, 83, 90 to 96, respectively. Conservative patients improved from time of injury to day 10 from 57 to 86 and then fell to 84 at 6 months. By 3 years, this had recovered to 91. There was no statistical significant difference in AMS (P=0.15)/change in AMS (ΔAMS) (P=0.92) or percentage of motor deficit resolution (P=0.23) between groups at 3 years. Two patients underwent surgery within 48 h and achieved full motor recovery by 3 years, but this was not significant (P=0.2). ASIA score improvement had a positive correlation with age at injury. Patients treated with surgery had better Rotterdam scores at 3 years than those managed conservatively (P=0.05). CONCLUSIONS:This study confirms the natural history of central cord syndrome. Although it demonstrates equivocal neurological recovery for both groups, patients treated with surgery regained a greater degree of functional independence.
journal_name
Spinal Cordjournal_title
Spinal cordauthors
Stevenson CM,Dargan DP,Warnock J,Sloan S,Espey R,Maguire S,Eames Ndoi
10.1038/sc.2016.34subject
Has Abstractpub_date
2016-11-01 00:00:00pages
1010-1015issue
11eissn
1362-4393issn
1476-5624pii
sc201634journal_volume
54pub_type
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