Abstract：
AIM:To determine whether cardiac magnetic resonance imaging (cMRI) is more sensitive than electrocardiogram (ECG) and echocardiogram (ECHO) for detecting myocardial involvement in a Latin American migrant population with untreated Chagas disease (CD) in the United States. MATERIALS AND METHODS:All untreated CD patients with ECG and ECHO examinations who underwent cMRI at Olive View-UCLA Medical Center from September 2010 to December 2013 (n=81) were analysed in three groups: Group 1, normal ECG and ECHO examinations (n=50); Group 2, abnormal ECG and normal ECHO examinations (n=10); and Group 3, abnormal ECHO examination (n=21). Frequencies of ECG, ECHO, and cMRI findings were compared across groups. RESULTS:Seventy percent (57/81) of the study population was female, with a mean age of 47 years (range, 17-77 years). Twenty-six percent (21/81) had delayed myocardial enhancement (DME), which was most commonly inferolateral in location (27%, 32/117 segments) and transmural in pattern (56%, 65/117 segments). Eight percent (4/50), 30% (3/10), and 67% (14/21) of Groups 1-3, respectively, had DME. Of these individuals with DME, 50% (2/4), 67% (2/3), and 100% (14/14) of Groups 1-3, respectively, also had wall motion abnormality (WMA) on cMRI. In addition to the highest percentages of DME and WMA, Group 3 also had significantly higher mean myocardial mass (p<0.01), mean left ventricular end-diastolic (p<0.01) and end-systolic volumes (p<0.0005), and significantly lower mean left ventricular ejection fraction (p<0.001). CONCLUSION:cMRI may detect myocardial involvement in untreated CD that is otherwise unrecognised on ECG and ECHO.
journal_name
Clin Radioljournal_title
Clinical radiologyauthors
Lee-Felker SA,Thomas M,Felker ER,Traina M,Salih M,Hernandez S,Bradfield J,Lee M,Meymandi Sdoi
10.1016/j.crad.2016.02.015subject
Has Abstractpub_date
2016-06-01 00:00:00pages
618.e1-7issue
6eissn
0009-9260issn
1365-229Xpii
S0009-9260(16)00091-Xjournal_volume
71pub_type
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journal_title：Clinical radiology
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journal_title：Clinical radiology
pub_type： 杂志文章
doi：10.1016/s0009-9260(77)80105-0
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