The basal ganglia: from motor commands to the control of vigor.

Abstract:

:Vertebrates are remarkable for their ability to select and execute goal-directed actions: motor skills critical for thriving in complex, competitive environments. A key aspect of a motor skill is the ability to execute its component movements over a range of speeds, amplitudes and frequencies (vigor). Recent work has indicated that a subcortical circuit, the basal ganglia, is a critical determinant of movement vigor in rodents and primates. We propose that the basal ganglia evolved from a circuit that in lower vertebrates and some mammals is sufficient to directly command simple or stereotyped movements to one that indirectly controls the vigor of goal-directed movements. The implications of a dual role of the basal ganglia in the control of vigor and response to reward are also discussed.

journal_name

Curr Opin Neurobiol

authors

Dudman JT,Krakauer JW

doi

10.1016/j.conb.2016.02.005

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

158-166

eissn

0959-4388

issn

1873-6882

pii

S0959-4388(16)30006-X

journal_volume

37

pub_type

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