Uterine tumors in ataxia-telangiectasia.

Abstract:

:Roughly one-third of patients with ataxia-telangiectasia (AT) develop malignant tumors, usually of lymphoid origin. AT patients also exhibit progeric changes. We describe three patients, between the ages of 27 and 32 years, with uterine tumors: one with a frank leiomyosarcoma and chronic T-cell leukemia, one with a multilobulated leiomyoma of uncertain malignant potential, and one with an unremarkable leiomyoma. Thus, the spectrum of tumors in AT patients beyond adolescence includes nonlymphoid malignancies and precocious, benign leiomyomas.

journal_name

Gynecol Oncol

journal_title

Gynecologic oncology

authors

Gatti RA,Nieberg R,Boder E

doi

10.1016/s0090-8258(89)80045-9

subject

Has Abstract

pub_date

1989-02-01 00:00:00

pages

257-60

issue

2

eissn

0090-8258

issn

1095-6859

pii

S0090-8258(89)80045-9

journal_volume

32

pub_type

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