Abstract:
:In this article, we develop new methods for estimating average treatment effects in observational studies, in settings with more than two treatment levels, assuming unconfoundedness given pretreatment variables. We emphasize propensity score subclassification and matching methods which have been among the most popular methods in the binary treatment literature. Whereas the literature has suggested that these particular propensity-based methods do not naturally extend to the multi-level treatment case, we show, using the concept of weak unconfoundedness and the notion of the generalized propensity score, that adjusting for a scalar function of the pretreatment variables removes all biases associated with observed pretreatment variables. We apply the proposed methods to an analysis of the effect of treatments for fibromyalgia. We also carry out a simulation study to assess the finite sample performance of the methods relative to previously proposed methods.
journal_name
Biometricsjournal_title
Biometricsauthors
Yang S,Imbens GW,Cui Z,Faries DE,Kadziola Zdoi
10.1111/biom.12505subject
Has Abstractpub_date
2016-12-01 00:00:00pages
1055-1065issue
4eissn
0006-341Xissn
1541-0420journal_volume
72pub_type
杂志文章相关文献
BIOMETRICS文献大全abstract::This article describes the theoretical and practical issues in experimental design for gene expression microarrays. Specifically, this article 1) discusses the basic principles of design (randomization, replication, and blocking) as they pertain to microarrays, and 2) provides some general guidelines for statisticians...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2003.00096.x
更新日期:2003-12-01 00:00:00
abstract::In a study designed to assess the relationship between a dichotomous exposure and the eventual occurrence of a dichotomous outcome, frequency matching has been proposed as a way to balance the exposure cohorts with respect to the sampling distribution of potential confounding factors. This paper discusses the pooled e...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::This article proposes an efficient approach to screening genes associated with a phenotypic variable of interest in genomic studies with subgroups. In order to capture and detect various association profiles across subgroups, we flexibly estimate the underlying effect size distribution across subgroups using a semi-pa...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12716
更新日期:2018-03-01 00:00:00
abstract::In a period starting around 2007, the Hand, Foot, and Mouth Disease (HFMD) became wide-spreading in China, and the Chinese public health was seriously threatened. To prevent the outbreak of infectious diseases like HFMD, effective disease surveillance systems would be especially helpful to give signals of disease outb...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12301
更新日期:2015-09-01 00:00:00
abstract::Within the framework of Fisher's discriminant analysis, we propose a multiclass classification method which embeds variable screening for ultrahigh-dimensional predictors. Leveraging interfeature correlations, we show that the proposed linear classifier recovers informative features with probability tending to one and...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13065
更新日期:2019-12-01 00:00:00
abstract::This paper focuses on the methodology developed for analyzing a multivariate interval-censored data set from an AIDS observational study. A purpose of the study was to determine the natural history of the opportunistic infection cytomeglovirus (CMV) in an HIV-infected individual. For this observational study, laborato...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2000.00940.x
更新日期:2000-09-01 00:00:00
abstract::Interval-censored failure time data occur in many fields such as demography, economics, medical research, and reliability and many inference procedures on them have been developed (Sun, 2006; Chen, Sun, and Peace, 2012). However, most of the existing approaches assume that the mechanism that yields interval censoring ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12527
更新日期:2016-12-01 00:00:00
abstract::Suppose that a heterogeneous group of individuals is followed over time and that each individual can be in state 0 or state 1 at each time point. The sequence of states is assumed to follow a binary Markov chain. In this paper we model the transition probabilities for the 0 to 0 and 1 to 0 transitions by two logistic ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::Increasingly, genetic studies of tumors of the same histologic diagnosis are elucidating subtypes that are distinct with respect to clinical endpoints such as response to treatment and survival. This raises concerns about the efficiency of using the simple log-rank test for analysis of treatment effect on survival in ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2002.00232.x
更新日期:2002-03-01 00:00:00
abstract::The class of admissible tests for Hardy-Weinberg equilibrium in a multi-allelic system is characterized. The standard goodness-of-fit chi-square tests is shown to be admissible for systems of two or more alleles. The conditional probability distribution required to determine the exact significance level of this test i...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::Calibration, the statistical consistency of forecast distributions and the observations, is a central requirement for probabilistic predictions. Calibration of continuous forecasts is typically assessed using the probability integral transform histogram. In this article, we propose significance tests based on scoring ...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2010.01406.x
更新日期:2010-12-01 00:00:00
abstract::Let Yi be an ni X 1 vector of observations, Xi an ni X p matrix of known values, and beta an unknown p X 1 with the structure Yi = Xi beta + epsilon i, where the covariance matrix of epsilon i is of intra-class form, that is Cov (epsilon i) = sigma2[(1 - rho) Ii + rho e i e i'] where Ii is the ni X ni identity matrix ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1975-09-01 00:00:00
abstract::We derive a likelihood score method for interval estimation of the intraclass version of the kappa coefficient of agreement with binary classification using a general theory of Bartlett (1953, Biometrika 40, 306-317). By exact evaluation, we investigate statistical properties of the score method, the chi-square goodne...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2000.00583.x
更新日期:2000-06-01 00:00:00
abstract::Ranked set sampling (RSS) utilizes inexpensive auxiliary information about the ranking of the units in a sample to provide a more precise estimator of the population mean of the variable of interest Y, which is either difficult or expensive to measure. However, the ranking may not be perfect in most situations. In thi...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1997-09-01 00:00:00
abstract::When a true survival endpoint cannot be assessed for some subjects, an alternative endpoint that measures the true endpoint with error may be collected, which often occurs when obtaining the true endpoint is too invasive or costly. We develop an estimated likelihood function for the situation where we have both uncert...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12316
更新日期:2015-09-01 00:00:00
abstract::A new test using incidence data is developed for testing whether two or more groups have the same seasonal pattern. The method fits sine waves to the data with a fundamental period of one cycle per year, and has the possibility of using higher harmonics, when necessary, to adequately model the data. The seasonal patte...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract::An individual's health condition can affect the frequency and intensity of episodes that can occur repeatedly and that may be related to an event time of interest. For example, bleeding episodes during pregnancy may indicate problems predictive of preterm delivery. Motivated by this application, we propose a joint mod...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2006.00720.x
更新日期:2007-06-01 00:00:00
abstract::An adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations. The test statistic is a direct statistical analogue of the popular "funnel-graph." The number of component studies in the meta-analysis, the...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1994-12-01 00:00:00
abstract::This note provides a discussion on the manuscript by Wang et al. (2005) who aim to robustify inference for longitudinal data analysis by replacing the ordinary generalized estimating function with an influence-bounded, possibly biased, version. To adjust for the bias of the ensuing robust estimator, the authors provid...
journal_title:Biometrics
pub_type: 信件
doi:10.1111/biom.13263
更新日期:2020-09-01 00:00:00
abstract::Power and sample-size formulas for testing the homogeneity of relative risks using the score method are presented. The homogeneity score test (Gart, 1985, Biometrika 72, 673-677) is formally equivalent to the Pearson chi-square test, although they look different. Results of this paper may be useful in assessing the va...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.1999.00289.x
更新日期:1999-03-01 00:00:00
abstract::Conditional likelihood based on counting processes are combined with a Horvitz-Thompson estimator to yield a population size estimator that is more efficient than the existing ones. Random removals are allowed in the recapturing process. Simulation studies are shown to assess the performance of the proposed estimators...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.0006-341x.2002.00192.x
更新日期:2002-03-01 00:00:00
abstract::For the analysis of time trends in incidence and mortality rates, the age-period-cohort (apc) model has became a widely accepted method. The considered data are arranged in a two-way table by age group and calendar period, which are mostly subdivided into 5- or 10-year intervals. The disadvantage of this approach is t...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1997-03-01 00:00:00
abstract::Large amounts of longitudinal health records are now available for dynamic monitoring of the underlying processes governing the observations. However, the health status progression across time is not typically observed directly: records are observed only when a subject interacts with the system, yielding irregular and...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.13261
更新日期:2020-03-11 00:00:00
abstract::Brownie, Boos, and Hughes-Oliver (1990, Biometrics 46, 259-266) suggested a modification to the fixed-effects analysis of variance (ANOVA) F test for use in situations where treatments are likely to affect mean response while simultaneously increasing between-subject variability. These authors suggest that the modifie...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1993-09-01 00:00:00
abstract::The Wilcoxon rank sum test is widely used for two-group comparisons for nonnormal data. An assumption of this test is independence of sampling units both between and within groups. In ophthalmology, data are often collected on two eyes of an individual, which are highly correlated. In ophthalmological clinical trials,...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2006.00582.x
更新日期:2006-12-01 00:00:00
abstract::In many longitudinal clinical studies, the level and progression rate of repeatedly measured biomarkers on each subject quantify the severity of the disease and that subject's susceptibility to progression of the disease. It is of scientific and clinical interest to relate such quantities to a later time-to-event clin...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/j.1541-0420.2008.01168.x
更新日期:2009-09-01 00:00:00
abstract::Experimental designs that include repeated measures of binary response variables over time and under different conditions are common in biology. In such settings, it is often desirable to characterize the response pattern over time. When response variables are continuous, this characterization can be made in terms of ...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1988-12-01 00:00:00
abstract::Logistic regression is a popular tool for risk analysis in medical and population health science. With continuous response data, it is common to create a dichotomous outcome for logistic regression analysis by specifying a threshold for positivity. Fitting a linear regression to the nondichotomized response variable a...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12007
更新日期:2013-06-01 00:00:00
abstract::Truncation is a well-known phenomenon that may be present in observational studies of time-to-event data. While many methods exist to adjust for either left or right truncation, there are very few methods that adjust for simultaneous left and right truncation, also known as double truncation. We propose a Cox regressi...
journal_title:Biometrics
pub_type: 杂志文章
doi:10.1111/biom.12809
更新日期:2018-06-01 00:00:00
abstract::Prentice and Sheppard (1995, Biometrika 82, 113-125) proposed a method for estimating relative risks associated with poorly measured exposures using disease rates from multiple populations and exposure and confounding factor data from sample surveys of persons in each population. The method involved an assumption of i...
journal_title:Biometrics
pub_type: 杂志文章
doi:
更新日期:1998-12-01 00:00:00