当前位置： SCI文献检索 > JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS期刊下所有文献 > A facile and selective approach for enrichment of l-cysteine in human plasma sample based on zinc organic polymer: Optimization by response surface methodology.

A facile and selective approach for enrichment of l-cysteine in human plasma sample based on zinc organic polymer: Optimization by response surface methodology.

Abstract：

:In this research, a facile and selective method was described to extract l-cysteine (l-Cys), an essential α-amino acid for anti-ageing playing an important role in human health, from human blood plasma sample. The importance of this research was the mild and time-consuming synthesis of zinc organic polymer (Zn-MOP) as an adsorbent and evaluation of its ability for efficient enrichment of l-Cys by ultrasound-assisted dispersive micro solid-phase extraction (UA-DMSPE) method. The structure of Zn-MOP was investigated by FT-IR, XRD and SEM. Analysis of variance (ANOVA) was applied for the experimental data to reach the best optimum conditions. The quantification of l-Cys was carried out by high performance liquid chromatography with UV detection set at λ=230nm. The calibration graph showed reasonable linear responses towards l-Cys concentrations in the range of 4.0-1000μg/L (r2=0.999) with low limit of detection (0.76μg/L, S/N=3) and RSD≤2.18 (n=3). The results revealed the applicability and high performance of this novel strategy in detecting trace l-Cys by Zn-MOP in complicated matrices.

journal_name

J Pharm Biomed Anal

journal_title

Journal of pharmaceutical and biomedical analysis

authors

Bahrani S,Ghaedi M,Ostovan A,Javadian H,Mansoorkhani MJK,Taghipour T

doi

10.1016/j.jpba.2017.10.040

subject

Has Abstract

pub_date

2018-02-05 00:00:00

pages

166-171

eissn

0731-7085

issn

1873-264X

pii

S0731-7085(17)30105-X

journal_volume

149

pub_type

杂志文章

相关文献

JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS文献大全
  • Comparative studies on glycoproteins expressing polylactosamine-type N-glycans in cancer cells.

    abstract：:In the series of our previous reports, we showed that some cancer cell lines specifically express polylactosamine-type N-glycans and such glycans were often modified with fucose and sulfate residues. To confirm the proteins expressing these glycans, glycopeptide mixture obtained by digestion of whole protein fractions...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2012.06.035

    authors： Mitsui Y,Yamada K,Hara S,Kinoshita M,Hayakawa T,Kakehi K

    更新日期：2012-11-01 00:00:00

  • New polyvinyl chloride membrane electrode without inner reference solution for the determination of methadone.

    abstract：:A PVC membrane electrode, without inner reference solution, based on an ion association extraction system responding to methadone (MD) is described. It incorporates a methadone-tetrakis(4-chlorophenyl)borate ion-pair complex in 2-nitrophenyloctyl ether. The prepared electrode exhibits a near Nernstian response (59.5 m...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/s0731-7085(02)00694-5

    authors： Khalil S,Kelzieh A

    更新日期：2003-03-10 00:00:00

  • Acute lung injury therapeutic mechanism exploration for Chinese classic prescription Qingzao Jiufei Decoction by UFLC-MS/MS quantification of bile acids, fatty acids and eicosanoids in rats.

    abstract：:Acute lung injury (ALI) is a common and complex inflammatory disease, which has been reasonably associated with carboxyl-containing metabolites in our preliminary non-targeted metabolomic strategy. Qingzao Jiufei Decoction (QZJFD), a classic prescription, is widely used in the treatment of pulmonary inflammatory injuri...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2020.113463

    authors： Wang T,Lin S,Liu R,Li H,Liu Z,Xu H,Li Q,Bi K

    更新日期：2020-09-10 00:00:00

  • High-throughput assays on the chip based on metal nano-cluster resonance transducers.

    abstract：:High throughput transducers using metal cluster resonance technology are based on surface-enhancement of metal cluster light absorption. These devices can be used for detection of biorecognitive binding, as well as structural changes of nucleic acids, proteins or any other polymer. The optical property for the analyti...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/s0731-7085(00)00545-8

    authors： Mayer C,Stich N,Palkovits R,Bauer G,Pittner F,Schalkhammer T

    更新日期：2001-03-01 00:00:00

  • Rapid determination of recent cocaine use with magnetic particles-based enzyme immunoassays in serum, saliva, and urine fluids.

    abstract：:Cocaine is one of the most worldwide used illicit drugs. We report a magnetic particles-based enzyme-linked immunoassay (mpEIA) method for the rapid and sensitive determination of cocaine (COC) in saliva, urine and serum samples. Under optimized conditions, the limits of detections were 0.09ngmL(-1) (urine), 0.15ngmL(...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2016.03.004

    authors： Vidal JC,Bertolín JR,Bonel L,Asturias L,Arcos-Martínez MJ,Castillo JR

    更新日期：2016-06-05 00:00:00

  • Restoration of hepatocytes function following decompression therapy in extrahepatic biliary obstructed patients: metabolite profiling of bile by NMR.

    abstract：:Prolonged biliary obstruction and infection cause retention of biliary constituents in liver followed by hepatocyte dysfunction. Decompression therapy is important for both management and prognostic reasons and restores hepatocyte function. Quantitative metabolite profiling of bile using NMR spectroscopy at the time o...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2011.04.010

    authors： Bala L,Tripathi P,Choudhuri G,Khetrapal CL

    更新日期：2011-08-25 00:00:00

  • Determination of carotenoids and their esters in fruits of Lycium barbarum Linnaeus by HPLC-DAD-APCI-MS.

    abstract：:The fruit of Lycium barbarum Linnaeus, a traditional Chinese herb containing functional components such as carotenoids, flavonoids and polysaccharides, has been widely used in the health food industry because of its possible role in the prevention of chronic disease like age-related macular degeneration. The objective...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2008.04.001

    authors： Inbaraj BS,Lu H,Hung CF,Wu WB,Lin CL,Chen BH

    更新日期：2008-08-05 00:00:00

  • The physicochemical properties of oestradiol.

    abstract：:The spectral, solubility and related physicochemical characteristics of the ovarian hormone are presented. A review of its crystal properties indicates that the common crystalline form of the steroid is the hemihydrate. ...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/0731-7085(87)80076-6

    authors： Salole EG

    更新日期：1987-01-01 00:00:00

  • Rapid and reliable determination of illegal adulterant in herbal medicines and dietary supplements by LC/MS/MS.

    abstract：:In recent years, dietary supplements and herbal medicines are increasing in popularity all over the world. However, it is problematic that some manufacturers illegally included synthetic drugs in their products. Due to the extremely complex matrices of those products, most existing methods for screening illegal adulte...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2005.07.035

    authors： Liang Q,Qu J,Luo G,Wang Y

    更新日期：2006-02-13 00:00:00

  • A spectroscopic investigation of DuP 747 polymorphs.

    abstract：:DuP 747, a selective kappa agonist analgesic, was found to have at least two polymorphic forms, and this was confirmed by X-ray powder diffraction. DSC and thermomicroscopic studies indicated the polymorphic pair to be monotropic. Solubility studies suggested the relative stability of the two forms to be similar. The ...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/0731-7085(94)e0002-i

    authors： Raghavan K,Dwivedi A,Campbell GC Jr,Nemeth G,Hussain MA

    更新日期：1994-06-01 00:00:00

  • Simultaneous measurement of amiodarone and desethylamiodarone in human plasma and serum by stable isotope dilution liquid chromatography-tandem mass spectrometry assay.

    abstract：:A stable isotope dilution liquid chromatography-electrospray ionization tandem mass spectrometry (LC-MS/MS) assay to measure amiodarone, the most frequently used agent for maintaining sinus rhythm in patients with atrial fibrillation, and its major metabolite desethylamiodarone in human plasma and serum was developed....

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2009.08.004

    authors： Kuhn J,Götting C,Kleesiek K

    更新日期：2010-01-05 00:00:00

  • Extremely long time stability study of selected antibiotic standards.

    abstract：:A study was conducted to investigate the quality of reference substances which were produced long before the introduction of advanced analysis and purification techniques. The quality and antimicrobial activity of WHO and EP oxytetracycline, doxycycline, colistin and spiramycin reference standards were assessed. The o...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2009.09.031

    authors： German R,Bukowska B,Pajchel G,Grzybowska W,Tyski S

    更新日期：2010-02-05 00:00:00

  • Cloud-point extraction is compatible with liquid chromatography coupled to electrospray ionization mass spectrometry for the determination of antazoline in human plasma.

    abstract：:Cloud-point extraction (CPE) is attracting increasing interest in a number of analytical fields, including bioanalysis, as it provides a simple, safe and environmentally-friendly sample preparation technique. However, there are only few reports on the application of this extraction technique in liquid chromatography-e...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2016.05.042

    authors： Giebułtowicz J,Kojro G,Piotrowski R,Kułakowski P,Wroczyński P

    更新日期：2016-09-05 00:00:00

  • Simultaneous determination of 5-aminosalicylic acid, acetyl-5-aminosalicylic acid and 2,5-dihydroxybenzoic acid in endoscopic intestinal biopsy samples in humans by high-performance liquid chromatography with electrochemical detection.

    abstract：:A high-performance liquid chromatographic method for the simultaneous determination of 5-aminosalicylic acid (5-ASA), acetyl-5-aminosalicylic acid (Ac-5-ASA) and 2,5-dihydroxybenzoic acid (5-HSA) in human endoscopic intestinal biopsy with electrochemical detection has been developed and validated. A liquid-liquid extr...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/0731-7085(95)01608-2

    authors： Palumbo G,Carlucci G,Mazzeo P,Frieri G,Pimpo MT,Fanini D

    更新日期：1995-12-01 00:00:00

  • Forced degradation study of racecadotril: Effect of co-solvent, characterization of degradation products by UHPLC-Q-TOF-MS/MS, NMR and cytotoxicity assay.

    abstract：:Racecadotril, an enkephalinase inhibitor, was subjected to hydrolysis (acidic and alkaline), oxidation, photolysis and thermal stress, as per ICH specified conditions. The drug showed extensive degradation under acidic, basic hydrolysis and oxidative stress conditions whereas, it was stable under other stress conditio...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2016.05.008

    authors： Chiguru V,Lingesh A,R S,N S

    更新日期：2016-09-05 00:00:00

  • Exploration and classification of chromatographic fingerprints as additional tool for identification and quality control of several Artemisia species.

    abstract：:The World Health Organization accepts chromatographic fingerprints as a tool for identification and quality control of herbal medicines. This is the first study in which the distinction, identification and quality control of four different Artemisia species, i.e. Artemisia vulgaris, A. absinthium, A. annua and A. capi...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2014.02.006

    authors： Alaerts G,Pieters S,Logie H,Van Erps J,Merino-Arévalo M,Dejaegher B,Smeyers-Verbeke J,Vander Heyden Y

    更新日期：2014-07-01 00:00:00

  • Bioanalytical method for evaluating the pharmacokinetics of the GCP-II inhibitor 2-phosphonomethyl pentanedioic acid (2-PMPA).

    abstract：:2-Phosphonomethyl pentanedioic acid (2-PMPA) is a potent and selective inhibitor of glutamate carboxypeptidase-II, an enzyme which catabolizes the abundant neuropeptide N-acetyl-aspartyl-glutamate (NAAG) to N-acetylaspartate (NAA) and glutamate. 2-PMPA demonstrates robust efficacy in numerous animal models of neurolog...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2013.08.028

    authors： Rais R,Rojas C,Wozniak K,Wu Y,Zhao M,Tsukamoto T,Rudek MA,Slusher BS

    更新日期：2014-01-01 00:00:00

  • Determination of boldine in drug formulations by first-derivative synchronous spectrofluorimetry.

    abstract：:A simple and sensitive method is proposed for the determination of boldine by first-derivative synchronous spectrofluorimetry based on its native fluorescence in 0.1 N sulphuric acid. The constant wavelength difference (delta lambda = lambda em--lambda ex) chosen to optimize the determination is 90 nm. The linear conc...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/0731-7085(94)90005-1

    authors： Vilchez JL,Sánchez-Palencia G,Avidad R,Navalón A

    更新日期：1994-03-01 00:00:00

  • Development and validation of an ICP-MS method for the determination of elemental impurities in TP-6076 active pharmaceutical ingredient (API) according to USP 〈232〉/〈233〉.

    abstract：:The new guidelines of the United States pharmacopeia (USP), European pharmacopeia (EP) and international conference on harmonization (ICH) regulating elemental impurities limits in pharmaceuticals signify the end of unspecific analysis of metals as outlined in USP 〈231〉. The new guidelines specify both daily doses and...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2017.06.045

    authors： Chahrour O,Malone J,Collins M,Salmon V,Greenan C,Bombardier A,Ma Z,Dunwoody N

    更新日期：2017-10-25 00:00:00

  • Quantification of endostar in rat plasma by LC-MS/MS and its application in a pharmacokinetic study.

    abstract：:LC-MS/MS is a promising analytical platform for the quantification of recombinant therapeutic proteins in biological fluids for pharmacokinetic (PK) studies. Herein, an absolute quantification method based on LC-MS/MS technique was developed to quantify endostar, which is modified from the recombinant human endostatin...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2012.07.017

    authors： Li YC,Liang Y,Tang ZY,Xiao YN,Hao HP,Wang GJ

    更新日期：2012-11-01 00:00:00

  • Pharmacokinetic and tissue distribution studies of 1,9-pyrazoloanthrone, a c-Jun-N-terminal kinase inhibitor in Wistar rats by a simple and sensitive HPLC method.

    abstract：:JNK pathway activates c-Jun(s) which are responsible for cell apoptosis; as a result, inhibitors of JNK pathway have the potential to prevent dopaminergic neurons from death and decrease the loss of dopamine in substantia nigra pars compacta (SNpc). Recent in-vitro studies show that 1,9-pyrazoloanthrone (1,9-P) a pote...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2015.12.004

    authors： Ambhore NS,Yamjala K,Mohire S,Raju KR,Mulukutla S,Murthy V,Tondhawada M,Elango K

    更新日期：2016-02-20 00:00:00

  • Acetone immersion enhanced MALDI-MS imaging of small molecule metabolites in biological tissues.

    abstract：:Profiling the endogenous tissue metabolites with spatial features is significant for our understanding of molecular histology, and provides an insightful way to uncover the complex associations between tissue metabolic response and external stimuli. Matrix-assisted laser desorption/ionization mass spectrometry imaging...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2019.112797

    authors： Sun C,Li Z,Ma C,Zang Q,Li J,Liu W,Zhao H,Wang X

    更新日期：2019-11-30 00:00:00

  • Separation of cis-beta-lactam enantiomers by capillary electrophoresis using cyclodextrin derivatives.

    abstract：:Chiral separation of 19 pairs of cis-beta-lactam (BL) stereoisomers of pharmacological importance was examined by capillary electrophoresis using cyclodextrin (CD) derivatives. In order to select the most effective conditions separating the highest number of stereoisomers of BLs, single carboxymethyl alpha-, beta- and...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2010.04.026

    authors： Németh K,Varga E,Iványi R,Szemán J,Visy J,Jicsinszky L,Szente L,Forró E,Fülöp F,Péter A,Simonyi M

    更新日期：2010-11-02 00:00:00

  • Advances in the chemical constituents and chemical analysis of Ginkgo biloba leaf, extract, and phytopharmaceuticals.

    abstract：:Ginkgo biloba leaf (GBL) is an important botanical drug that can be used for treating many diseases. This review summarizes the reported chemical constituents from GBL or Ginkgo biloba extract (GBE) to date, as well as the recent advances in the extraction, purification, qualitative and quantitative analysis methods (...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章,评审

    doi：10.1016/j.jpba.2020.113704

    authors： Liu L,Wang Y,Zhang J,Wang S

    更新日期：2021-01-30 00:00:00

  • Bioanalysis of cisplatin analogues--a selective review.

    abstract：:A variety of analytical procedures have been described for the determination of cisplatin and its analogues in biological fluids (plasma, plasma ultrafiltrate and urine), as well as in solid tissues. This paper attempts to review those methods which have been most commonly used in practice. These analytical methods ma...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/0731-7085(88)80078-5

    authors： Riley CM

    更新日期：1988-01-01 00:00:00

  • Identification of Ligustici Rhizoma et Radix and its adulterants based on their chemical constituents by UHPLC-Q/TOF-MS combined with data mining.

    abstract：:Ligustici Rhizoma et Radix (LR), known as Gaoben (GB) in Chinese, has been used in traditional Chinese medicine for more than 2000 years. However, the varieties of LR are not well characterized at present, and traditional recognition methods have encountered increasing difficulties. This research attempts to distingui...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2018.02.053

    authors： Lei XQ,Li G,Cheng L,Wang XL,Meng FY

    更新日期：2018-05-30 00:00:00

  • Identification of a new impurity in lisinopril.

    abstract：:LC-UV scan of lisinopril revealed the presence of an unknown impurity (approximately 0.14%) at a relative retention time of 3.26 employing phosphate buffer-acetonitrile as binary gradient system while LC-MS analysis with binary gradient system comprising of a ammonia-ammonium acetate buffer (pH 5.0) and acetonitrile i...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2006.06.046

    authors： Shinde V,Trivedi A,Upadhayay PR,Gupta NL,Kanase DG,Chikate R

    更新日期：2007-01-04 00:00:00

  • LC determination of Z-338, novel gastroprokinetic agent in dog plasma by SCX solid phase extraction.

    abstract：:A simple high-performance liquid chromatographic assay with using UV detection (266 nm) was developed to determine a novel gastroprokinetic agent, Z-338 in dog plasma. The extraction procedure using solid-phase extraction with a Isolute SCX column produces extremely clean eluates and a high recovery. Intra- and inter-...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/s0731-7085(00)00593-8

    authors： Furuta S,Miyahara H,Sugimoto T,Sano H

    更新日期：2001-06-01 00:00:00

  • Quantitative three-dimensional analysis of poly (lactic-co-glycolic acid) microsphere using hard X-ray nano-tomography revealed correlation between structural parameters and drug burst release.

    abstract：:The objective of this study was to investigate the use of transmission hard X-ray nano-computed-tomography (nano-CT) for characterization of the pore structure and drug distribution in poly (lactic-co-glycolic acid) (PLGA) microspheres encapsulating bovine serum albumin and to study the correlation between drug distri...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/j.jpba.2015.04.017

    authors： Huang X,Li N,Wang D,Luo Y,Wu Z,Guo Z,Jin Q,Liu Z,Huang Y,Zhang Y,Wu C

    更新日期：2015-08-10 00:00:00

  • A rapid and sensitive method for simultaneous determination of insulin and A21-desamido insulin by high-performance liquid chromatography.

    abstract：:A reversed-phase high-performance liquid chromatography (RP-HPLC) method with UV-detection at room temperature has been developed for the analysis of insulin and its main degradation product, A21-desamido insulin. Octadecylsilica was used as stationary phase and a mixture of water and acetonitrile containing tetramety...

    journal_title：Journal of pharmaceutical and biomedical analysis

    pub_type： 杂志文章

    doi：10.1016/s0731-7085(03)00336-4

    authors： Moslemi P,Najafabadi AR,Tajerzadeh H

    更新日期：2003-09-15 00:00:00