Abstract:
INTRODUCTION:Sedation is a core concept in the intensive care setting, however, the impact of sedation on delirium has not yet been studied to date. METHODS:In this prospective cohort study, 225 patients with Richmond Agitation and Sedation (RASS) scores of -1 - drowsiness and 0 - alert- and calmness were assessed with the Delirium Rating Scale-Revised 1998 (DRS-R-98) and DSM-IV-TR-determined diagnosis of delirium assessing drowsiness versus alertness. RESULTS:By itself, drowsiness increased the odds for developing delirium eightfold (OR 7.88 p<0.001) and rates of delirium were 68.2 and 21.4%, respectively. Further, in the drowsy patient, delirium was more severe. In the presence of drowsiness, delirium was characterized by sleep-wake cycle disturbances and language abnormalities. These two features, in addition to psychomotor retardation, allowed the correct classification of delirium at RASS-1. The same features, in addition to thought abnormalities and the impairment in the cognitive domain, orientation, attention, short- and long-term memory representing the core domains of delirium, or the temporal onset were very sensitive towards delirium, however lacked specificity. Conversely, delusions, perceptual abnormalities and lability of affect representing the non-core domain were very specific for delirium in the drowsy, however, not very sensitive. In the absence of delirium, drowsiness caused attentional impairment and language abnormalities. CONCLUSION:Drowsiness increased the odds for developing delirium eightfold and caused more severe delirium, which was characterized by sleep-wake cycle and language abnormalities. Further, drowsiness by itself caused attentional impairment and language abnormalities, thus, with its disturbance in consciousness was subthreshold for delirium.
journal_name
J Psychosom Resjournal_title
Journal of psychosomatic researchauthors
Boettger S,Nuñez DG,Meyer R,Richter A,Fernandez SF,Rudiger A,Schubert M,Jenewein Jdoi
10.1016/j.jpsychores.2017.09.011subject
Has Abstractpub_date
2017-12-01 00:00:00pages
133-139eissn
0022-3999issn
1879-1360pii
S0022-3999(17)30917-0journal_volume
103pub_type
杂志文章abstract:OBJECTIVES:To examine the associations between a wide range of mental disorders and subsequent onset of stroke. Lifecourse timing of stroke was examined using retrospectively reconstructed data from cross-sectional surveys. METHODS:Data from the World Mental Health Surveys were accessed. This data was collected from g...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2015.05.008
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:To explore the association between depressive symptom history and cancer incidence. METHODS:Affective/emotional depressive symptoms were assessed using the General Health Questionnaire (GHQ-30) depression sub-scale across phase 1 (1985-1988), phase 2 (1989-1990), and phase 3 (1991-1994) of the Whitehall II p...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2015.07.011
更新日期:2015-12-01 00:00:00
abstract:OBJECTIVE:Current models assume somatoform pain disorder (SPD) to be the result of a complex interaction between bio- and psychosocial factors, but the etiology is still not well understood. This study aimed to investigate the distribution of attachment style and the frequency of traumatic life events, especially child...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2017.10.003
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine whether or not conversion symptoms are lateralized. Studies have shown a predominant left-oriented manifestation of symptoms for most somatoform disorders. The reports in the literature on the lateralization of conversion symptoms, however, are rather conflicting. Th...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/s0022-3999(00)00075-1
更新日期:2000-07-01 00:00:00
abstract::Thirty eight children and adolescents between the ages of 10 and 17 years were examined for an association between diabetic control and psychological health determined by questionnaires to examine self concept, locus of control and family cohesion and adaptability. The group as a whole had a high score on the self est...
journal_title:Journal of psychosomatic research
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doi:10.1016/0022-3999(87)90057-2
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:Some peer reviewers may inappropriately, or coercively request that authors include references to the reviewers' own work. The objective of this study was to evaluate whether, compared to reviews for a journal with single-blind peer review, reviews for a journal with open peer review included (1) fewer self-c...
journal_title:Journal of psychosomatic research
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doi:10.1016/j.jpsychores.2015.08.004
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:It is hypothesized that somatic symptom alleviation is a significant predictor of overall outcome in depressed primary care patients. METHODS:Depressed primary care patients (N=205) meeting DSM-IV-TR criteria received open-label antidepressant therapy. The primary symptom measurement tool used was the 17-it...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2005.09.010
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:This study sought to determine the frequency of use and types of antidepressants used in IBD patients and to collect data with respect to any effect of antidepressants on the course of IBD in a usual care setting. METHOD:A case-note audit was conducted at an IBD Service in a public tertiary hospital. Include...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2011.06.006
更新日期:2012-02-01 00:00:00
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journal_title:Journal of psychosomatic research
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doi:10.1016/j.jpsychores.2018.01.005
更新日期:2018-03-01 00:00:00
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更新日期:2019-10-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2014.07.018
更新日期:2014-10-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2005.02.010
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:Anxiety disorders and symptoms are highly prevalent and problematic comorbidities in people with epilepsy (PWE), yet they remain poorly understood and often go undetected. This research aimed to further our understanding about anxiety in PWE. METHODS:Study 1 assessed the effectiveness of the commonly utilise...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2014.12.002
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVE:The 'psychogenic' hypothesis has a long history in the field of infertility. The present study investigated whether anxiety or depressive symptoms are associated with probability of subsequent live birth in a cohort of infertile women from the general population. METHODS:Using linked data from 12,987 women i...
journal_title:Journal of psychosomatic research
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doi:10.1016/j.jpsychores.2018.07.001
更新日期:2018-10-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章,评审
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更新日期:2004-04-01 00:00:00
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doi:10.1016/j.jpsychores.2019.109795
更新日期:2019-10-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/0022-3999(89)90027-5
更新日期:1989-01-01 00:00:00
abstract::This report describes the construction of a questionnaire to measure three dimensions of human eating behavior. The first step was a collation of items from two existing questionnaires that measure the related concepts of 'restrained eating' and 'latent obesity', to which were added items newly written to elucidate th...
journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/0022-3999(85)90010-8
更新日期:1985-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.jpsychores.2009.09.012
更新日期:2010-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2000-01-01 00:00:00
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更新日期:2000-02-01 00:00:00
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journal_title:Journal of psychosomatic research
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更新日期:2019-08-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
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更新日期:2006-10-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/0022-3999(90)90033-z
更新日期:1990-01-01 00:00:00
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journal_title:Journal of psychosomatic research
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doi:10.1016/0022-3999(86)90014-0
更新日期:1986-01-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/s0022-3999(00)00159-8
更新日期:2000-09-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2004.08.004
更新日期:2005-02-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2017.07.007
更新日期:2017-09-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/S0022-3999(03)00041-2
更新日期:2004-01-01 00:00:00
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journal_title:Journal of psychosomatic research
pub_type: 杂志文章
doi:10.1016/j.jpsychores.2006.11.001
更新日期:2007-06-01 00:00:00