A Novel Application for Cognitive Evaluation in Mountain Ultramarathons: Olfactory Assessment.

Abstract:

OBJECTIVE:Olfactory function, a cognitive impairment biomarker, was evaluated in mountain ultramarathon (MUM) runners during the Tor des Géants race (332.5 km with an overall altitude gain of 24,000 m; altitude range 330-3296 m above the sea). METHODS:An Odor Identification Test was administered before (T0; n = 53), at 148.7 kms (T1; n = 32) and after the race (T2; n = 28). The effect of dehydration and sleep deprivation on olfactory function was assessed. Olfactory function was also assessed in non-MUM athletes and sedentary controls (C) at rest. RESULTS:A majority of the athletes completed the olfactory test at all time intervals. Olfactory function decreased throughout the race (T0: 13.8 ± 1.9, T1: 13.7 ± 1.6, T2: 13.1 ± 1.8; T0 vs T2 P = .01). There was no relationship with race time or sleep deprivation on the sense of smell throughout the competition. However, there was a combined effect with decreased olfaction during the second half of the race, while a poor relationship was seen between olfaction and total body water at midterm (T1: rs = -0.427; P = .019), but not at baseline or after the race. MUM athletes had similar olfactory scores to C (13.8 ± 1.9 vs 13.7 ± 1.4) and non-MUM (13.8 ± 1.9 vs 13.9 ± 1.6) athletes. CONCLUSIONS:This pilot study showed the feasibility of olfactory evaluation as a minimally invasive cognitive impairment assessment. The test can be used in logistically difficult environments, adding scientific value to this promising method. Although olfaction decreased after prolonged physical activity, further studies are warranted to make the relationship between cognition and external factors (eg, sleep deprivation, dehydration) more clear.

journal_name

Wilderness Environ Med

authors

Tonacci A,Billeci L,Tartarisco G,Mastorci F,Borghini A,Mrakic-Sposta S,Moretti S,Vezzoli A,Faraguna U,Pioggia G,Guido G,Pratali L

doi

10.1016/j.wem.2015.11.013

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

131-5

issue

1

eissn

1080-6032

issn

1545-1534

pii

S1080-6032(15)00459-7

journal_volume

27

pub_type

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