Polymer Particulates in Drug Delivery.

Abstract:

:Development of effective drug delivery systems is important for medicine and healthcare. Polymer particulates (micro- and nanoparticles) have opened new opportunities in the field of drug delivery by overcoming various limitations of conventional delivery methods. The properties of polymeric particles can be readily tuned by precisely engineering the constituent blocks of polymers for improving drug loading, release rate, pharmacokinetics, targeting, etc. The end-groups of various polymers can be readily modified with ligands making them suitable for recognizing by cell-specific receptors, providing cellular specificity, and superior intracellular delivery. This review will mainly cover delivery of many potential drugs and biomolecules by means of polymeric microparticles, nanoparticles and copolymer micelles or assemblies. An overview about formulation methods of polymer particulates has also been addressed. Attempt has been made to cover all the potential polymers that are well known in pharmaceutical history.

journal_name

Curr Pharm Des

authors

Kaur H,Kumar V,Kumar K,Rathor S,Kumari P,Singh J

doi

10.2174/1381612822666160217125734

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

2761-87

issue

19

eissn

1381-6128

issn

1873-4286

pii

CPD-EPUB-73789

journal_volume

22

pub_type

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