Abstract：
BACKGROUND:Radiation therapy is an effective treatment for primary brain tumors and intracranial metastases but can occasionally precede new enhancing lesions on imaging studies that are difficult to discern between tumor recurrence (TR) and radiation necrosis (RN). The aim of this study was to identify clinical presentation and imaging patterns of RN compared with TR that may obviate the need for invasive definitive biopsy. METHODS:Patients who received radiation therapy and subsequently presented with a new intracranial lesion were reviewed from 2001 to 2016; 27 patients were identified with adequate records and confirmed pathology to have RN present or TR only. Patient and lesion characteristics were assessed using univariate and multivariate logistic regression analyses. Sensitivity and specificities were calculated for imaging features and quantitatively segmented lesion and edema volumes for identifying RN. RESULTS:Karnofsky performance scale score at presentation significantly predicted pathologic diagnosis on univariate analysis (P = 0.044). Radiation dosage and time from radiation therapy to lesion onset did not differ among pathologic diagnosis groups. No differences existed between RN and TR on quantitative imaging analyses. Multivariate logistic regression found higher Karnofsky performance scale score to be an independent factor associated with TR relative to RN (odds ratio 1.26, 95% confidence interval 1.02-1.56, P = 0.030). CONCLUSIONS:Diagnostic imaging can often be inaccurate in detecting RN alone, even with quantitative volume assessment. Functional status on repeat presentation may increase the likelihood of accurate diagnosis before definitive biopsy when neuroimaging remains unclear.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Feng R,Loewenstern J,Aggarwal A,Pawha P,Gilani A,Iloreta AM,Bakst R,Miles B,Bederson J,Costa A,Gupta V,Shrivastava RKdoi
10.1016/j.wneu.2017.12.104subject
Has Abstractpub_date
2018-03-01 00:00:00pages
e485-e494eissn
1878-8750issn
1878-8769pii
S1878-8750(17)32220-9journal_volume
111pub_type
杂志文章abstract：BACKGROUND:Heterotopic ossification (HO) and anterior bone loss (ABL) are 2 complications in cervical disc replacement (CDR), which have impacts on the clinical outcomes. Physiologically, bone formation (HO) and bone loss are 2 sides of bone remodeling. However, clinically, some patients experienced anterior HO (AHO) a...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.01.022
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Spontaneous resolution of acute subdural hematomas (SDHs), occurring as the result of a traumatic injury, is well reported in the literature and rapidly resolving SDHs have been reported as well. Although the mechanism behind the rapid resolution of a SDH has not been well understood, there are postulated me...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.029
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:We present a case of multiple myxoma-related intracranial aneurysms and reviewed the recent relevant literature to investigate their natural course and develop a reasonable treatment algorithm. METHODS:We have reported a new case of multiple myxoma-related intracranial aneurysms and performed a search of cur...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.09.014
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:Mirror intracranial aneurysms with different rupture status is a useful model to investigate features associated with aneurysm rupture. Morphological and hemodynamic analyses of ruptured middle cerebral artery (MCA) mirror aneurysms are rarely reported. The purpose of this study was to determine the morpholo...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.01.083
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Paragangliomas are neuroendocrine tumors that originate from autonomic nervous system-associated paraganglia and are rare tumors accounting for only 0.3% of all neoplasms. Malignant paragangliomas frequently spread to the skeleton. The authors present a case of malignant paraganglioma with bone metastases to...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.09.102
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Vagus nerve stimulation (VNS) has become an increasingly popular procedure for the treatment of epilepsy and depression. Significant complications or side effects associated with VNS surgery may result from either the inadvertent direct injury to the vagus nerve as part of the surgical approach, placement of...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.08.014
更新日期：2019-11-01 00:00:00
abstract：BACKGROUND:The minimally invasive approach to distal anterior cerebral artery (DACA) aneurysms has not gained much acceptance due to difficulties associated with the conventional frontal paramedian approach. The more proximal basal interhemispheric approach, however, necessitates extensive dissection of soft tissues. W...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2018.01.100
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVE:Prognostic factors of favorable and unfavorable clinical outcome after aneurysmal subarachnoid hemorrhage (SAH) are still not completely known. We retrospectively analyzed the aneurysm location as a factor for patients' outcome after aneurysmal SAH. METHODS:We retrospectively selected patients from our prosp...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.04.086
更新日期：2016-08-01 00:00:00
abstract：BACKGROUND:Diastatic skull fractures (DSFs) in children are difficult to detect in skull radiographs before they develop into growing skull fractures; therefore, little information is available on this topic. However, recent advances in 3-dimensional (3D) computed tomography (CT) imaging technology have enabled more ac...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.08.107
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Various radiologic patterns of posterior reversible encephalopathy syndrome (PRES) have been reported. Among them, PRES involving brainstem, thalamus, or deep white matter and lacking parieto-occipital edema is rare. Although PRES in general has a benign course, PRES-related intracranial hemorrhage has been ...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.10.196
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Primary central nervous system neuroblastoma (PCNSN) is a rare disease, and its incidence, treatment modalities, and survival remain poorly understood. METHODS:The SEER (Surveillance Epidemiology and End Results) database was used to identify patients diagnosed with PCNSN from 1973 to 2013. The incidence an...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.04.145
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:To explore the superior frontal sulcus (SFS) morphology, trajectory of the applied surgical corridor, and white matter bundles that are traversed during the superior frontal transsulcal transventricular approach. METHODS:Twenty normal, adult, formalin-fixed cerebral hemispheres and 2 cadaveric heads were inc...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.06.161
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:This anatomic study aimed to more precisely locate the bifurcation of the obturator nerve in relationship to the obturator foramen. Such information might improve outcomes in neurotization or other procedures necessitating exposure of the obturator nerve and could increase success rates for obturator nerve b...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.03.113
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to determine whether combined diffusion-weighted imaging and dynamic susceptibility contrast-enhanced perfusion-weighted imaging magnetic resonance imaging can be used to differentiate between common malignant brain tumors, including lymphomas and high-grade gliomas. METHODS:We ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.10.141
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVE:The pathophysiologic mechanisms underlying cerebral vasospasm after aneurysmal subarachnoid hemorrhage (aSAH) remain poorly understand. Ryanodine receptors (RYR) are intracellular calcium channels involved in the regulation of vascular smooth muscle cells and cerebrovascular tone and diameter. Previous work r...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2016.12.132
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Spinal dural arteriovenous fistulas (DAVFs) and spinal arteriovenous malformations (AVMs) are relatively rare. Moreover, multiple spinal cord vascular lesions in an individual, such as double DAVFs and DAVF with AVM, are extremely rare. To date, there are only several reported cases of concomitant spinal DAV...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.06.022
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:Reducing complications from unruptured aneurysms (UAs) treatment is important. We clarify the criteria for achieving safe and complete treatment for UAs ≤10 mm by clipping or coil embolization. METHODS:This study included 59 newly treated UAs in the past 2 years. We prospectively decided on criteria to recom...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.04.005
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Tumors protruding into the cerebral aqueduct are rare, and tumors arising from within the cerebral aqueduct are rarer still. CASE DESCRIPTION:In this report, we discuss the presentation and clinical outcome of a 65-year-old man who presented to us with symptoms of hydrocephalus. Prior imaging had revealed a...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.03.206
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:Aneurysm surgery demands precise spatial understanding of the vascular anatomy and its surroundings. We report on a decade of experience planning clipping procedures preoperatively in a virtual reality (VR) workstation and present outcomes with respect to mortality, morbidity, and aneurysm occlusion rate. ME...
journal_title：World neurosurgery
pub_type： 杂志文章,多中心研究
doi：10.1016/j.wneu.2016.08.124
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:Percutaneous endoscopic lumbar discectomy is an effective way to treat lumbar disc herniation. Traditional preoperative planning based on a 2-dimensional method by magnetic resonance/computed tomography may cause inaccuracy of puncture during surgery. We used virtual reality to stimulate a surgery environment...
journal_title：World neurosurgery
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.wneu.2018.08.082
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:Proximal junctional kyphosis (PJK) is a well-recognized complication following surgery for adult spinal deformity (ASD); however, definitions for PJK and its clinical implications can significantly vary by study. This study compares multiple definitions of PJK and describes incidence and clinical significanc...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.10.034
更新日期：2020-10-20 00:00:00
abstract：BACKGROUND:The benefit of prophylactic antibiotic use in endoscopic endonasal transsphenoidal surgery (EETS) for pituitary lesions is controversial. Many surgeons administer antibiotics perioperatively not based on clear guidelines but to be safe. The purpose of this study was to determine if antibiotic prophylaxis use...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.082
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Approximately 2%-10% of all central nervous system tumors are primary spinal cord tumors (SCTs). Spinal cord glioblastoma is a rare tumor type accounting for 1%-3% of all SCTs and 7.5% of all spinal cord gliomas. Notably, the small-cell variant of spinal cord glioblastoma is even rarer with only 2 previously...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2018.07.007
更新日期：2018-10-01 00:00:00
abstract：:Abraham Lincoln was the 16(th) President of the United States of America. On April 14, 1865, shortly after his re-election and the conclusion of the Civil War, Lincoln was shot and killed by John Wilkes Booth. Although numerous physicians tended to the President shortly after his injury, he passed away the next mornin...
journal_title：World neurosurgery
pub_type： 传,历史文章,杂志文章,评审
doi：10.1016/j.wneu.2015.06.011
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Acute bilateral isolated foot drop due to lumbar disk prolapse with canal stenosis is rare with only 3 cases reported in literature. Our patient was managed using the percutaneous full endoscopic technique. This is mainly to highlight the ease of access and patient outcome with preoperative and postoperative...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.11.128
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Sedation therapy is vital for treating severe traumatic brain injury (TBI). Yet, types of sedation assessment tools and sedation levels that are suitable for sedation treatment have not been investigated. OBJECTIVE:To investigate the influence of different sedation levels guided by the Bispectral Index (BIS...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.11.079
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Brain aneurysms (BAs) are the most common intracranial vascular condition, with an overall incidence of 1%-2%. Among the common causes of their initial formation and growth, the role of radiation therapy (RT) has been reported in some studies. The aim of the present study is to report the most relevant featu...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.09.157
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:Direct surgery for complex internal carotid artery (ICA) aneurysms can be difficult. In certain situations, sacrificing the parent artery is a unique way to obliterate the aneurysm and extracranial-to-intracranial (EC-IC) bypass is indispensable to prevent postoperative cerebral ischemia. This article discuss...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.07.043
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:Incomplete penetration of a burr hole sometimes occurs when performing a craniotomy in elderly patients due to osteoporosis. Completion of the burr hole takes more time and may sometimes cause tearing of the dura mater. We have introduced a small bone piece method that can easily and reliably recover an inco...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.080
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:Meningeal hemangiopericytoma (HPC) is a rare, aggressive central nervous system tumor that tends to invade locally and to metastasize, and has a high rate of recurrence. METHODS:This study presents a retrospective review of patients managed for intracranial HPC at Rome University Hospital. RESULTS:A total o...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2013.11.009
更新日期：2014-03-01 00:00:00
