Effect of early nutritional intake on long-term growth and bone mineralization of former very low birth weight infants.

Abstract:

BACKGROUND:Preterm infants are at risk for impaired bone mineralization and growth in length later in life due to inadequate nutritional intake in the early postnatal period. OBJECTIVE:To investigate whether increased nutritional supplementation of calcium, phosphate and protein in Very Low Birth Weight (VLBW) infants during the first 14days after birth was associated with improvement in length and bone development until 9-10years of age. DESIGN:Observational follow-up study of VLBW infants (birth weight<1500g or gestational age<32weeks) born in two consecutive years (eligible infants: 2004 n: 63 and 2005: n: 66). Cohort 2005 received higher intake of calcium, phosphate and protein with parenteral nutrition compared to Cohort 2004. Anthropometric data were collected during standard follow-up visits until five years, and additionally at 9-10years of age including measurements of bone mineral content, bone mineral density of the whole body and lumbar spine determined by dual-energy X-ray absorptiometry. Long-term growth trajectories of both cohorts were evaluated separately for participants born appropriate (AGA) and small for gestational age (SGA), stratified by gender. Multivariate linear regression was used to examine the effect of nutritional intake and clinical covariates on length and bone mineralization. RESULTS:Both cohorts achieved a catch-up in length to SDS within the normal range by 6months (length SDS: estimated mean (95% confidence interval (CI): 6months: Cohort 2004: -0.7 (-1.1, -0.3) Cohort 2005: -0.5 (-0.8, -0.2)). Bone mineral content and density were within the normal range and not different between the cohorts. SGA children achieved a catch-up in length at 5years with bone mineralization comparable to AGA children. Only for girls birth weight was significantly associated with length SDS (per gram: β 0.001; 95% CI (0.000, 0.003); p=0.03) There was no evidence of an association between early nutritional intake and bone mineralization. CONCLUSION:Children born as appropriate or small for gestational age preterm infants are able to catch up in length after the postnatal period, and achieve a normal length and bone mineralization at age nine-ten years. An improvement of calcium and phosphate intake during the first 14days after birth was not associated with improvement in length and bone development.

journal_name

Bone

journal_title

Bone

authors

Christmann V,van der Putten ME,Rodwell L,Steiner K,Gotthardt M,van Goudoever JB,van Heijst AFJ

doi

10.1016/j.bone.2017.12.022

subject

Has Abstract

pub_date

2018-03-01 00:00:00

pages

89-97

eissn

8756-3282

issn

1873-2763

pii

S8756-3282(17)30482-9

journal_volume

108

pub_type

杂志文章

相关文献

BONE文献大全
  • Leptin regulates chondrocyte differentiation and matrix maturation during endochondral ossification.

    abstract::Leptin has been suggested to mediate a variety of actions, including bone development, via its ubiquitously expressed receptor (Ob-Rb). In this study, we investigated the role of leptin in endochondral ossification at the growth plate. The growth plates of wild-type and ob/ob mice were analyzed. Effects of leptin on c...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2005.05.009

    authors: Kishida Y,Hirao M,Tamai N,Nampei A,Fujimoto T,Nakase T,Shimizu N,Yoshikawa H,Myoui A

    更新日期:2005-11-01 00:00:00

  • Evaluation of vertebral volumetric vs. areal bone mineral density during growth.

    abstract::Bone mineral "density" (BMD) measured by dual-energy X-ray absorptiometry (DEXA) does not represent the volumetric density (grams per cubic centimeter), but rather the areal density (grams per square centimeter). This distinction is important during growth. The purpose of this study was to measure vertebral dimensions...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/s8756-3282(97)00057-4

    authors: Ott SM,O'Hanlan M,Lipkin EW,Newell-Morris L

    更新日期:1997-06-01 00:00:00

  • Whole-exome sequencing reveals a heterozygous LRP5 mutation in a 6-year-old boy with vertebral compression fractures and low trabecular bone density.

    abstract::Juvenile osteoporosis (JO) is characterized by bone fragility during development, low bone mass and absence of extraskeletal features. Heterozygous loss-of-function mutations in LRP5 have been found in a few patients, but bone tissue and bone material abnormalities associated with such mutations have not been determin...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2013.07.020

    authors: Fahiminiya S,Majewski J,Roughley P,Roschger P,Klaushofer K,Rauch F

    更新日期:2013-11-01 00:00:00

  • Effects of low-dose parathyroid hormone on bone mass, turnover, and ectopic osteoinduction in a rat model for chronic alcohol abuse.

    abstract::Parathyroid hormone (PTH) is used clinically in osteoporotic patients to increase bone mass by enhancing bone formation. PTH therapy is not uniformly effective at all skeletal sites and "life-style" factors may modulate the skeletal response to PTH. Alcohol may represent one of these factors. Chronic alcohol abuse is ...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2007.12.221

    authors: Iwaniec UT,Trevisiol CH,Maddalozzo GF,Rosen CJ,Turner RT

    更新日期:2008-04-01 00:00:00

  • Effect of zoledronate acid treatment on osseointegration and fixation of implants in autologous iliac bone grafts in ovariectomized rabbits.

    abstract::One main problem associated with alveolar bone augmentation in implant dentistry is resorption of grafted bone, which may be further compromised by systemic skeletal disorders such as osteoporosis. Zoledronate acid (ZOL) is the most potent bisphosphonate to treat osteoporosis and therefore it is hypothesized to be abl...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2011.10.011

    authors: Qi M,Hu J,Li J,Li J,Dong W,Feng X,Yu J

    更新日期:2012-01-01 00:00:00

  • Prevalence of rickets-like bone deformities in rural Gambian children.

    abstract::The aim of this study was to estimate the burden of childhood rickets-like bone deformity in a rural region of West Africa where rickets has been reported in association with a low calcium intake. A population-based survey of children aged 0.5-17.9 years living in the province of West Kiang, The Gambia was conducted i...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2015.04.011

    authors: Jones HL,Jammeh L,Owens S,Fulford AJ,Moore SE,Pettifor JM,Prentice A

    更新日期:2015-08-01 00:00:00

  • Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization capacity.

    abstract:PURPOSE:Clinical and in vitro studies suggest that subchondral bone sclerosis due to abnormal osteoblasts is involved in the progression of osteoarthritis (OA). Human osteoblasts isolated from sclerotic subchondral OA bone tissue show an altered phenotype, a decreased canonical Wnt/ß-catenin pathway, and a reduced mine...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2015.02.001

    authors: Abed E,Bouvard B,Martineau X,Jouzeau JY,Reboul P,Lajeunesse D

    更新日期:2015-06-01 00:00:00

  • Three-dimensional cultures of normal human osteoblasts: proliferation and differentiation potential in vitro and upon ectopic implantation in nude mice.

    abstract::We report the establishment in vitro of three-dimensional (3D) cultures of human osteoblasts (hOB) derived from normal adults and supported uniquely by the extracellular matrix (ECM) they deposit. Osteoblasts were cultured in 3D cultures in vitro for up to 120 days. The 3D cultures, examined at 25, 31, and 48 days, ex...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/s8756-3282(02)00691-9

    authors: Ferrera D,Poggi S,Biassoni C,Dickson GR,Astigiano S,Barbieri O,Favre A,Franzi AT,Strangio A,Federici A,Manduca P

    更新日期:2002-05-01 00:00:00

  • Association of ALPL and ENPP1 gene polymorphisms with bone strength related skeletal traits in a Chuvashian population.

    abstract::Mineralization of the extracellular matrix of bone is an essential element of bone development, maintenance and repair. ALPL and ENPP1 genes and their products are known to be central in local regulation of bone mineralization. The present study investigates potential associations of ENPP1 and ALPL polymorphisms with ...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2009.11.018

    authors: Ermakov S,Toliat MR,Cohen Z,Malkin I,Altmüller J,Livshits G,Nürnberg P

    更新日期:2010-05-01 00:00:00

  • Osteonecrosis of the jaws (ONJ) in mice after extraction of teeth with periradicular disease.

    abstract::Osteonecrosis of the jaws (ONJ) is a complication of antiresorptive medications, such as denosumab or bisphosphonates, prescribed to patients with bone malignancy or osteoporosis. The most common instigating local factor in ONJ pathogenesis is tooth extraction. However, in adults the great majority of teeth are extrac...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2016.06.011

    authors: Soundia A,Hadaya D,Esfandi N,de Molon RS,Bezouglaia O,Dry SM,Pirih FQ,Aghaloo T,Tetradis S

    更新日期:2016-09-01 00:00:00

  • How B cells influence bone biology in health and disease.

    abstract::It is now well established that important regulatory interactions occur between the cells in the hematopoietic, immune and skeletal systems (osteoimmunology). B lymphocytes (B cells) are responsible for the generation and production of antibodies or immunoglobulins in the body. Together with T cells these lymphocytes ...

    journal_title:Bone

    pub_type: 杂志文章,评审

    doi:10.1016/j.bone.2010.06.011

    authors: Horowitz MC,Fretz JA,Lorenzo JA

    更新日期:2010-09-01 00:00:00

  • Histomorphometric analysis of the effects of osteocyte density on osteonal morphology and remodeling.

    abstract::Osteocytes, the most abundant cells in the cortical bone matrix, are thought to have mechanosensory and chemosensory regulatory roles. Marotti theorized that osteocytes signal to osteoblasts to recruit them into the osteocyte lineage. Martin extended this theory, assuming that osteocytes display a general inhibitory e...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/s8756-3282(03)00245-x

    authors: Metz LN,Martin RB,Turner AS

    更新日期:2003-11-01 00:00:00

  • Orchiectomy upregulates free soluble RANKL in bone marrow of aged rats.

    abstract::The osteoprotegerin (OPG)/receptor activator of NF-kappaB ligand (RANKL) axis is thought to be involved in the upregulation of bone turnover following sex steroid deficiency. Here, we investigated the effects of orchiectomy (ORX) on bone turnover and free soluble RANKL (sRANKL) in aged rats. Free, bioactive sRANKL is ...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2009.05.024

    authors: Proell V,Xu H,Schüler C,Weber K,Hofbauer LC,Erben RG

    更新日期:2009-10-01 00:00:00

  • Loss of myostatin (GDF8) function increases osteogenic differentiation of bone marrow-derived mesenchymal stem cells but the osteogenic effect is ablated with unloading.

    abstract::Myostatin (GDF8) is a negative regulator of skeletal muscle growth and mice lacking myostatin show a significant increase in muscle mass and bone density compared to normal mice. In order to further define the role of myostatin in regulating bone mass we sought to determine if loss of myostatin function significantly ...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2007.02.012

    authors: Hamrick MW,Shi X,Zhang W,Pennington C,Thakore H,Haque M,Kang B,Isales CM,Fulzele S,Wenger KH

    更新日期:2007-06-01 00:00:00

  • Intravital bone imaging by two-photon excitation microscopy to identify osteocytic osteolysis in vivo.

    abstract::Bone is a highly dynamic organ in which several cell types function cooperatively. Among these, osteocytes have recently emerged as an important regulator of bone homeostasis, although their mechanism of regulation is unclear. Here, intravital bone imaging by two-photon excitation microscopy allowed us to directly vis...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2015.01.013

    authors: Sano H,Kikuta J,Furuya M,Kondo N,Endo N,Ishii M

    更新日期:2015-05-01 00:00:00

  • Focal changes in blood supply during normal epiphyseal growth are central in the pathogenesis of osteochondrosis in pigs.

    abstract::Cartilage canals are temporary vessel-containing structures within the growth cartilage. The canals gradually regress with age in a process designated chondrification, where the content of the canals is replaced by cartilage. The process of chondrification is considered physiological; however, premature regression has...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2004.08.016

    authors: Ytrehus B,Ekman S,Carlson CS,Teige J,Reinholt FP

    更新日期:2004-12-01 00:00:00

  • Evaluation of the role of second messenger systems in tumor necrosis factor-stimulated resorption of fetal rat limb bones.

    abstract::Tumor necrosis factor (TNF) actions in target tissues are mediated by various signalling pathways. The effect of TNF to stimulate resorption in fetal rat limb bones is not inhibited by indomethacin. The current studies were designed to assess the role of cyclic AMP (cAMP) and calcium as second messengers in this prost...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/8756-3282(93)90317-4

    authors: Shankar G,Stern PH

    更新日期:1993-11-01 00:00:00

  • Interaction between human umbilical vein endothelial cells and human osteoprogenitors triggers pleiotropic effect that may support osteoblastic function.

    abstract::Osteogenesis occurs in striking interaction with angiogenesis. There is growing evidence that endothelial cells are involved in the modulation of osteoblast differentiation. We hypothesized that primary human umbilical vein endothelial cells (HUVEC) should be able to modulate primary human osteoprogenitors (HOP) funct...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2008.01.025

    authors: Guillotin B,Bareille R,Bourget C,Bordenave L,Amédée J

    更新日期:2008-06-01 00:00:00

  • Cortical and trabecular bone at the radius and tibia in postmenopausal breast cancer patients: a Peripheral Quantitative Computed Tomography (pQCT) study.

    abstract::Bone morbidity associated with antineoplastic treatment is a significant health concern for postmenopausal breast cancer patients. Trials have demonstrated that adjuvant therapy with an Aromatase Inhibitor is associated with an increase in musculoskeletal disorders and bone fractures. The objective of this study was t...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2010.09.025

    authors: Szabo KA,Webber CE,Adachi JD,Tozer R,Gordon C,Papaioannou A

    更新日期:2011-02-01 00:00:00

  • Lifelong risk factors for osteoporosis and fractures in elderly women with low body mass index--a population-based study.

    abstract::Low body weight is associated with an increased risk for osteoporosis and fractures, but the contribution of other lifestyle related factors have not been previously studied within lean elderly women. The present study evaluated the association between lifelong lifestyle factors and bone density, falls and postmenopau...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2006.01.143

    authors: Korpelainen R,Korpelainen J,Heikkinen J,Väänänen K,Keinänen-Kiukaanniemi S

    更新日期:2006-08-01 00:00:00

  • Paradoxical Sost gene expression response to mechanical unloading in metaphyseal bone.

    abstract::The Sost gene encodes Sclerostin, an inhibitor of Wnt-signaling, generally considered a main response gene to mechanical loading in bone. Several papers describe that unloading leads to upregulation of Sost, which in turn may lead to loss of bone. These studies were based on whole bone homogenates or cortical bone. By...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2013.01.018

    authors: Macias BR,Aspenberg P,Agholme F

    更新日期:2013-04-01 00:00:00

  • Vector-averaged gravity-induced changes in cell signaling and vitamin D receptor activity in MG-63 cells are reversed by a 1,25-(OH)2D3 analog, EB1089.

    abstract::Skeletal unloading in an animal hindlimb suspension model and microgravity experienced by astronauts or as a result of prolonged bed rest causes site-specific losses in bone mineral density of 1%-2% per month. This is accompanied by reductions in circulating levels of 1,25-(OH)(2)D(3), the active metabolite of vitamin...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/s8756-3282(02)00836-0

    authors: Narayanan R,Smith CL,Weigel NL

    更新日期:2002-09-01 00:00:00

  • Identification of prevalent vertebral fractures using Vertebral Fracture Assessment (VFA) in asymptomatic postmenopausal women: A systematic review and meta-analysis.

    abstract:BACKGROUND:Vertebral fracture (VF) is the most common osteoporotic fracture in postmenopausal women, although most VFs are subclinical. Prevalent VFs are a significant predictor of subsequent fracture and therefore, identification of VF improves the identification of those with high fracture risk. The aim of present st...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2020.115358

    authors: Yang J,Mao Y,Nieves JW

    更新日期:2020-07-01 00:00:00

  • Effects of minodronic acid and alendronate on bone remodeling, microdamage accumulation, degree of mineralization and bone mechanical properties in ovariectomized cynomolgus monkeys.

    abstract::Suppression of bone remodeling by bisphosphonates leads to accumulation of microdamage in bone. If this microdamage develops due to suppressed repair of remodeling only, more potent bisphosphonates should cause more damage. In this study, we evaluated the effects of reduced bone turnover produced by a potent bisphosph...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2013.01.016

    authors: Yamagami Y,Mashiba T,Iwata K,Tanaka M,Nozaki K,Yamamoto T

    更新日期:2013-05-01 00:00:00

  • Preoperative hypoalbuminemia: Poor functional outcomes and quality of life after hip fracture surgery.

    abstract:AIMS:Hip fracture patients have severe deterioration of their quality of life and function after their injury. Markers of malnutrition such as low albumin and low body mass index (BMI) have been shown to increase mortality and complication rates but their effect on recovery of quality of life and function after hip fra...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/j.bone.2020.115567

    authors: Sim SD,Sim YE,Tay K,Howe TS,Png MA,Chang CCP,Abdullah HR,Koh JSB

    更新日期:2021-02-01 00:00:00

  • Alendronate has a residual effect on bone mass in postmenopausal Danish women up to 7 years after treatment withdrawal.

    abstract::Alendronate has been shown to reduce bone turnover and increase bone mass. However, little is known about the duration of the effect on bone after treatment withdrawal. The aim of this study was to investigate the long-term effects on bone mineral density (BMD) and bone turnover of various alendronate regimens after t...

    journal_title:Bone

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s8756-3282(03)00112-1

    authors: Bagger YZ,Tankó LB,Alexandersen P,Ravn P,Christiansen C

    更新日期:2003-09-01 00:00:00

  • A review on computer modeling of bone piezoelectricity and its application to bone adaptation and regeneration.

    abstract::Bone is a hierarchical, multiphasic and anisotropic structure which in addition possess piezoelectric properties. The generation of piezoelectricity in bone is a complex process which has been shown to play a key role both in bone adaptation and regeneration. In order to understand the complex biological, mechanical a...

    journal_title:Bone

    pub_type: 杂志文章,评审

    doi:10.1016/j.bone.2019.07.024

    authors: Mohammadkhah M,Marinkovic D,Zehn M,Checa S

    更新日期:2019-10-01 00:00:00

  • Teriparatide and the risk of nonvertebral fractures in women with postmenopausal osteoporosis.

    abstract:PURPOSE:In the Fracture Prevention Trial, the risks of any nonvertebral fracture (relative risk [RR] 0.65, P=0.04) and any fragility nonvertebral fracture (RR 0.47, P=0.02) were significantly reduced in the teriparatide 20 μg/day (teriparatide) versus placebo group. The purpose of this analysis was to examine the effic...

    journal_title:Bone

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.bone.2011.10.018

    authors: Krege JH,Wan X

    更新日期:2012-01-01 00:00:00

  • The short- and long-term effects of methotrexate on the rat skeleton.

    abstract::Both clinical and laboratory studies have shown that the chemotherapy drug, Methotrexate (MTX), has adverse short-term effects on bone. There are no studies that demonstrate the long-term response of bone to MTX. The purpose of this study was to determine the short- and long-term effects of MTX on bone volume, turnove...

    journal_title:Bone

    pub_type: 杂志文章

    doi:10.1016/8756-3282(94)00032-u

    authors: Wheeler DL,Vander Griend RA,Wronski TJ,Miller GJ,Keith EE,Graves JE

    更新日期:1995-02-01 00:00:00

  • Local communication on and within bone controls bone remodeling.

    abstract::Bone remodeling is required for healthy calcium homeostasis and for repair of damage occurring with stress and age. Osteoclasts resorb bone and osteoblasts form bone. These processes normally occur in a tightly regulated sequence of events, where the amount of formed bone equals the amount of resorbed bone, thereby re...

    journal_title:Bone

    pub_type: 杂志文章,评审

    doi:10.1016/j.bone.2009.03.671

    authors: Henriksen K,Neutzsky-Wulff AV,Bonewald LF,Karsdal MA

    更新日期:2009-06-01 00:00:00