Difficulties encountered in the emergency department by patients with hereditary angioedema experiencing acute attacks.

Abstract:

BACKGROUND:Hereditary angioedema (HAE) is a rare, potentially life-threatening disease characterized by recurrent angioedema attacks. Abdominal symptoms of HAE typically mimic numerous abdominal emergencies, which may result in a delay of correct diagnosis and inappropriate treatments. OBJECTIVE:We aimed to evaluate the difficulties experienced by patients with HAE in Turkish emergency departments (ED). METHODS:We conducted face-to-face interviews with patients with HAE by using a questionnaire regarding the clinical and demographic data of the patients and difficulties encountered during ED admissions. RESULTS:The mean (standard deviation) age of 34 patients with HAE (25 women, 9 men) was 36.2 ± 11.5 years and the mean (standard deviation) delay in diagnosis was 17.2 ± 9.7 years. Inappropriate treatment for HAE attacks was administered to 88.2% (n = 30) of patients in the ED, despite their diagnosis of HAE. The most frequent difficulty was "not knowing how to administer C1 inhibitor concentrate" (n = 11 [32.4%]). Other difficulties encountered were as follows: ED staff being unaware of HAE (n = 6 [17.6%]), lack of C1 inhibitor concentrate in the ED (n = 3 [8.8%]), and kept waiting for the appropriate treatment in triage despite their having angioedema in the head-and-neck region (n = 2 [5.9%]). CONCLUSION:Patients with HAE encounter difficulties in the ED, and the delay in diagnosis could be due to a low level of awareness regarding HAE. Therefore, the management of HAE in EDs requires improvement.

journal_name

Allergy Asthma Proc

authors

Ucar R,Arslan S,Baran M,Caliskaner AZ

doi

10.2500/aap.2016.37.3905

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

72-5

issue

1

eissn

1088-5412

issn

1539-6304

journal_volume

37

pub_type

杂志文章
  • Forced oscillometry is applicable to epidemiological settings to detect asthmatic children.

    abstract::Forced oscillometry (FOT) has been reported as a simple method to detect respiratory resistance (Rrs) changes. The aim of this study was to evaluate FOT capacity to detect children with clinical characteristics of asthma in a school setting. One thousand thirty children, 6-7 years old, were investigated by questionnai...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,多中心研究

    doi:10.2500/aap.2007.28.2965

    authors: Boccaccino A,Peroni DG,Pietrobelli A,Piacentini GL,Aversano MP,Spinosa E,Boner AL

    更新日期:2007-03-01 00:00:00

  • Antioxidant supplementation and exhaled nitric oxide in children with asthma.

    abstract:BACKGROUND:The effect of allergen avoidance on airway inflammation is similar to that observed with treatment with inhaled steroids, whereas inhaled steroids have no effect on oxidative stress-induced inflammation. OBJECTIVE:The aim of this study was to retrospectively evaluate the potential effect of an antioxidant d...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2016.37.3920

    authors: Tenero L,Piazza M,Zanoni L,Bodini A,Peroni D,Piacentini GL

    更新日期:2016-01-01 00:00:00

  • Inflammatory mediators in cystic fibrosis lung disease.

    abstract::Cystic fibrosis (CF) is a complex multisystem disorder caused by mutations in a membrane glycoprotein called the CF transmembrane regulator (CFTR), which has as its major function serving as a Cl- channel. The relationship between defects in CFTR and development of lung disease remains incompletely understood. Chronic...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:

    authors: Berger M

    更新日期:2002-01-01 00:00:00

  • Cost impact of monitoring exhaled nitric oxide in asthma management.

    abstract:BACKGROUND:Asthma guidelines recommend periodic assessment of impairment and risk factors to prevent exacerbations, which can lead to hospitalization and increased health care utilization and cost. According to recent meta-analysis data, fractional exhaled nitric oxide (FeNO) monitoring is associated with a 40-50% redu...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2018.39.4165

    authors: Arnold RJG,Layton A,Massanari M

    更新日期:2018-09-13 00:00:00

  • Efficacy of probiotic supplementary therapy for asthma, allergic rhinitis, and wheeze: a meta-analysis of randomized controlled trials.

    abstract::Background: Probiotic supplementary therapy to prevent allergic diseases, including asthma in children, has been widely explored in many randomized controlled trials. However, there is conflicting evidence on the effect of probiotic supplementation during pregnancy and infancy to the incidence of asthma and allergic r...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,meta分析

    doi:10.2500/aap.2019.40.4227

    authors: Du X,Wang L,Wu S,Yuan L,Tang S,Xiang Y,Qu X,Liu H,Qin X,Liu C

    更新日期:2019-07-01 00:00:00

  • The tale of the allergist's life: a series of interesting case reports.

    abstract::The practicing allergist has the unique opportunity to see an extraordinary variety of fascinating patients. Identifying the precise cause of the patient's complaints makes for a satisfying intellectual endeavor. This is exemplified by the description of nine cases seen in a university allergy clinic. The cases includ...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2008.29.3140

    authors: Slavin RG

    更新日期:2008-07-01 00:00:00

  • Relation of indoor and outdoor airborne fungal spore levels in the Kansas City metropolitan area.

    abstract:BACKGROUND:Environmental control is an important component of asthma management for persons with asthma. A damp indoor environment and elevated airborne spore levels are factors in housing environmental control. OBJECTIVES:We investigated if indoor airborne fungal spore levels correlated with outdoor ground-level airb...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2017.38.4030

    authors: Jara D,Portnoy J,Dhar M,Barnes C

    更新日期:2017-03-01 00:00:00

  • Cross-sectional study on Asthma Insights and Management in the Gulf and Russia.

    abstract::Background: Asthma is a chronic and complex lung disease that is not completely understood. It involves airway inflammation, reversible airflow obstruction, and bronchial hyperresponsiveness. The most common symptoms are recurrent wheezing, chest tightness, shortness of breath, and coughing. Objective: The Asthma Insi...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,多中心研究

    doi:10.2500/aap.2018.39.4180

    authors: Alzaabi A,Idrees M,Behbehani N,Khaitov MR,Tunceli K,Urdaneta E,Awad N,Safwat M

    更新日期:2018-11-16 00:00:00

  • Utilization and timeliness of an inpatient penicillin allergy evaluation.

    abstract:BACKGROUND:A history of penicillin allergy is associated with an increased risk of nosocomial infections because patients are exposed to non-beta lactam antibiotics. Ruling out inaccurate penicillin allergy during hospitalization decreases prescription of beta lactam antibiotics. However, the utilization of penicillin ...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2018.39.4118

    authors: Sacco KA,Chirila R,Libertin C,Hiroto B,Bhasin A,Johnson MM,Pongdee T,Burton MC

    更新日期:2018-05-01 00:00:00

  • Airway hyperreactivity: managing outcomes and new directions.

    abstract::Bronchial hyperreactivity is defined as an increased sensitivity to bronchoconstrictor stimuli. It is regarded as the physiological hallmark of bronchial asthma. It is usually associated with a positive family history of asthma, atopy, and evaluated total serum immunoglobulin E. Its prevalence in the normal population...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:

    authors: Bardana EJ Jr

    更新日期:2002-11-01 00:00:00

  • The natural course of eczema from birth to age 7 years and the association with asthma and allergic rhinitis: a population-based birth cohort study.

    abstract::Although "atopic march" is a popular concept, the relationship between eczema and subsequent asthma is far from clear. However, some cohort studies have shown the possibility of two different allergic phenotypes in those who present with early eczema in terms of their persistency. We checked the cohort data from 308,...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2013.34.3625

    authors: Shen CY,Lin MC,Lin HK,Lin CH,Fu LS,Fu YC

    更新日期:2013-01-01 00:00:00

  • Effect of staphylococcal enterotoxin B on specific antibody production in children with atopic dermatitis.

    abstract::Exotoxins secreted by Staphylococcus aureus have been identified as a possible trigger factor in atopic dermatitis (AD). We investigated the production and role of circulating antibodies, with specificity to staphylococcal enterotoxin B (SEB), in children with AD compared with those of healthy controls. The children w...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:

    authors: Sohn MH,Kim CH,Kim WK,Jang GC,Kim KE

    更新日期:2003-01-01 00:00:00

  • Rhinorrhea not responding to nasal corticosteroids.

    abstract::A woman with multiple illnesses including allergic rhinitis presented for a follow-up visit at our clinic with constant rhinorrhea for 2 weeks despite regular use of nasal corticosteroids. Two weeks earlier, after alcohol drinking and doubling some of her medications for missed doses, she fell on her face. The Emergen...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2007.28.3061

    authors: Patel PN,Oyefara B,Aarstad R,Bahna SL

    更新日期:2007-11-01 00:00:00

  • Natural history of hay fever: a 23-year follow-up of college students.

    abstract::The purpose of this study is to examine the natural history of hay fever among former college students who were diagnosed with this disease either before or after their freshman year. The diagnosis of hay fever or seasonal allergic rhinitis was based on a history of watery, itchy eyes, rhinorrhea, and sneezing occurri...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:10.2500/108854198778557728

    authors: Greisner WA 3rd,Settipane RJ,Settipane GA

    更新日期:1998-09-01 00:00:00

  • The association between hypovitaminosis D and pediatric allergic diseases: A Korean nationwide population-based study.

    abstract:BACKGROUND:There is still considerable disagreement regarding the role of vitamin D in the development or exacerbation of allergic diseases. OBJECTIVE:To investigate the association between serum vitamin D levels and recent symptoms of allergic diseases in elementary schoolchildren. METHODS:A nationwide cross-section...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2016.37.3957

    authors: Yang HK,Choi J,Kim WK,Lee SY,Park YM,Han MY,Kim HY,Hahm MI,Chae Y,Lee KJ,Kwon HJ,Ahn K,Kim J

    更新日期:2016-07-01 00:00:00

  • Relationship between atopic asthma and the population prevalence rates for asthma or atopy in children: atopic and nonatopic asthma in epidemiology.

    abstract::Innumerable articles have tried to solve the "continuing enigma of atopic and nonatopic asthma" but notwithstanding the strenuous efforts to substantiate the few well-known clinico-epidemiologic differences between these two forms of asthma most studies have hitherto generated inconclusive statements. In a recent stud...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:10.2500/aap.2009.30.3197

    authors: Ronchetti R,Jesenak M,Rennerova Z,Barreto M,Ronchetti F,Villa MP

    更新日期:2009-01-01 00:00:00

  • Nonsteroidal anti-inflammatory drug hypersensitivity among children.

    abstract:BACKGROUND:Nonsteroidal anti-inflammatory drugs (NSAID) are the second-most frequent drugs that cause hypersensitivity reactions among children. Studies related to NSAIDs hypersensitivity in children are limited. In this study, we aimed to evaluate children admitted with suspicion of NSAIDs reaction. METHOD:Between Ja...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2015.36.3858

    authors: Guvenir H,Dibek Misirlioglu E,Vezir E,Toyran M,Ginis T,Civelek E,Kocabas CN

    更新日期:2015-09-01 00:00:00

  • Multiple physical urticarias: report of three cases and review of the literature.

    abstract::The appearance of more than one physical urticaria (PU) in the same patient has been documented; cold urticaria or dermatographism in association with some other type of PU are encountered more frequently. Three female patients exhibiting multiple PUs simultaneously are presented. In one female patient four different ...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:

    authors: Pitsios C,Vithoulka A,Roumana A,Kompoti E,Kontou-Fili K

    更新日期:2003-09-01 00:00:00

  • The relationship between insect sting allergy treatment and patient anxiety and depression.

    abstract::Quality of life is affected by history of bee sting allergy. In addition, worry about being stung and also the need to use self-injection of medicine can create or increase anxiety, which can further compromise a patient's ability to enjoy the outdoors and participate in activities. We sought to determine the depressi...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2014.35.3751

    authors: Findeis S,Craig T

    更新日期:2014-05-01 00:00:00

  • A cost-effective approach to the diagnosis and treatment of the wheezing infant.

    abstract::Wheezing in infancy presents the clinician with at least two broad clinical problems. First is the task of distinguishing the common entities of bronchiolitis and asthma from rare, yet potentially life threatening illnesses that may present with wheezing. The second problem deals with the difficulties in distinguishin...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:10.2500/108854197778984446

    authors: Mamlok R

    更新日期:1997-05-01 00:00:00

  • Serum interleukin 17, interleukin 23, and interleukin 10 values in children with atopic eczema/dermatitis syndrome (AEDS): association with clinical severity and phenotype.

    abstract::To date cytokines profile in AEDS is poorly described in children. We evaluated the interleukin (IL)-17, IL-23, and IL-10 levels in atopic eczema/dermatitis syndrome (AEDS) children and healthy controls, in atopic AEDS (aAEDS) and nonatopic (naAEDS) subtypes and their relationship with disease severity. A total of 181...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2015.36.3808

    authors: Leonardi S,Cuppari C,Manti S,Filippelli M,Parisi GF,Borgia F,Briuglia S,Cannavò P,Salpietro A,Arrigo T,Salpietro C

    更新日期:2015-01-01 00:00:00

  • Potentially (near) fatal asthma.

    abstract::Potentially (near) fatal asthma (PFA) defines a subset of patients with asthma who are at increased risk for death from their disease. The diagnosis of PFA should motivate treating physicians, health professionals, and patients to be more aggressive in the monitoring, treatment, and control of this high-risk type of a...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2019.40.4257

    authors: Greenberger PA

    更新日期:2019-11-01 00:00:00

  • A comparison of intranasal corticosteroid, leukotriene receptor antagonist, and topical antihistamine in reducing symptoms of perennial allergic rhinitis as assessed through the Rhinitis Severity Score.

    abstract::Rhinitis symptom complex consists of rhinorrhea, congestion, itchy mucosa, itchy eyes, and sneezing. Available medications vary in their benefit for each of these symptoms. It was the purpose of this article to compare symptom reduction with three different classes of medications. Montelukast, azelastine, and budesoni...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:10.2500/aap.2010.31.3308

    authors: Sardana N,Santos C,Lehman E,Craig T

    更新日期:2010-01-01 00:00:00

  • Antihistamine onset of action: the importance to the patient.

    abstract::Although some older antihistamines have a relatively slow onset of action, modern agents indicate an efficacy between 1 and 3 hours of administration. For patients who use antihistamines regularly, a short onset of action is relatively unimportant. When antihistamines are used as needed, either because of poor complia...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:

    authors: Dolen WK

    更新日期:2004-03-01 00:00:00

  • Fever of unknown origin and isolated noncaseating granuloma of the marrow: could this be sarcoidosis?

    abstract::Fever of unknown origin (FUO) is both a clinical and a diagnostic challenge. Furthermore, an FUO case with isolated marrow noncaseating granuloma can further confound diagnosis. However, these two findings together may help narrow down the pathological possibilities. This article presents a case report of FUO and lymp...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,评审

    doi:10.2500/aap.2007.28.2982

    authors: Miller AC,Chacko T,Rashid RM,Ledford DK

    更新日期:2007-03-01 00:00:00

  • Efficacy of olopatadine ophthalmic solution 0.2% in reducing signs and symptoms of allergic conjunctivitis.

    abstract::Olopatadine hydrochloride ophthalmic solution 0.2% (Pataday, Alcon) is a new formulation of olopatadine hydrochloride ophthalmic solution, the first topical ocular antiallergic agent indicated for once-daily dosing. The aim of this study was to evaluate the safety, efficacy, onset, and duration of action of olopatadin...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章,随机对照试验

    doi:10.2500/aap.2007.28.3014

    authors: Abelson MB,Gomes PJ,Pasquine T,Edwards MR,Gross RD,Robertson SM

    更新日期:2007-07-01 00:00:00

  • Management of asthma in adults: do the patients get what they need--and want?

    abstract::Suboptimal asthma control may be caused by a combination of factors, such as nonadherence to guidelines, lack of compliance, and poor asthma education. The aim was to assess patients' knowledge of asthma and different management strategies, including patients' attitudes toward involvement in treatment decisions. The p...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2007.28.3001

    authors: Backer V,Ulrik CS,Harving H,Lange P,Søes-Petersen U,Plaschke PP

    更新日期:2007-05-01 00:00:00

  • Relationship of basic military trainee emergency department visits for asthma and San Antonio air quality.

    abstract::The U.S. Air Force conducts basic military training (BMT) in San Antonio, TX, an area with occasionally adverse air quality. Many individuals from the BMT population are evaluated for asthma symptoms. The relationship of air quality with these symptoms has not been studied in this population. This study examines the c...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:

    authors: Letz AG,Quinn JM

    更新日期:2005-11-01 00:00:00

  • Defining the effects of an inhaled corticosteroid and long-acting beta-agonist on therapeutic targets.

    abstract::The effects of inhaled corticosteroids (ICSs) and long-acting beta 2-agonists (LABAs) on therapeutic targets have significant clinical relevance regarding optimal management of asthma. Asthma pathophysiology involves two main components: smooth muscle dysfunction and airway inflammation. LABAs and ICSs provide complem...

    journal_title:Allergy and asthma proceedings

    pub_type: 指南,杂志文章,实务指引,评审

    doi:

    authors: Settipane RA,National Asthma Education and Prevention Program (NAEPP).

    更新日期:2003-03-01 00:00:00

  • Effect of omalizumab on outcomes in patients with aspirin-exacerbated respiratory disease.

    abstract::Background: The current treatment for patients with aspirin-exacerbated respiratory disease (AERD) who have uncontrolled asthma or chronic rhinosinusitis is aspirin desensitization. For patients who are unable to undergo or do not benefit from aspirin desensitization, treatment with biologics is an option, although ef...

    journal_title:Allergy and asthma proceedings

    pub_type: 杂志文章

    doi:10.2500/aap.2019.40.4241

    authors: Jean T,Eng V,Sheikh J,Kaplan MS,Goldberg B,Jau Yang S,Samant S

    更新日期:2019-09-01 00:00:00