Abstract:
BACKGROUND:To assess the safety and efficacy of oral propranolol in the management of periocular Capillary Hemangiomas of Infancy (CHI). METHODS:Medical records of 21 infants diagnosed with periocular capillary hemangioma during a period of 5 years from 2009 to 2014 were retrospectively reviewed. The data collected included demographic details, clinical features and details of imaging studies and response to the therapy. All patients received oral propranolol under the supervision of a pediatrician. The initial dose was 0.2-1 mg/kg body weight, which was increased to 2 mg/kg body weight (3 divided doses) in 48 h if there was no adverse reaction to the initial dose. The response to the treatment was assessed clinically as well as by radiographic imaging. Photographic documentation was done periodically. RESULTS:Out of 21 patients, 18 were females and remaining three were males. The median age at the time of presentation was 4 months. The most common presenting feature was lid mass (n = 17, 80%) followed by proptosis (n = 7, 33%). Reddish discoloration of face was seen in 2 (1%) patients. All patients showed reduction in the size of the lesion. None of the patients included in this study had any adverse reaction to propranolol or recurrence following cessation of the therapy. CONCLUSION:Oral propranolol is highly effective and safe in the treatment of periocular capillary hemangiomas in infants.
journal_name
Pediatr Neonatoljournal_title
Pediatrics and neonatologyauthors
Koka K,Mukherjee B,Agarkar Sdoi
10.1016/j.pedneo.2017.11.021subject
Has Abstractpub_date
2018-08-01 00:00:00pages
390-396issue
4eissn
1875-9572issn
2212-1692pii
S1875-9572(16)30310-2journal_volume
59pub_type
杂志文章abstract:BACKGROUND:To evaluate the occurrence of constipation after anorectal malformations (ARM) repair and the results of laxative treatment. METHODS:Between August 2012 and July 2017, the clinical data of patients with ARMs was prospectively collected. The patients were divided into two groups, good types and poor types. G...
journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
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abstract:BACKGROUND:The most severe form of pneumococcal disease is invasive pneumococcal disease (IPD), including empyema, sepsis and meningitis. Thomsen-Friedenreich antigen (TA; Galβ1-3GalNAc) activation is known to be a predictor of Streptococcus pneumoniae-associated hemolytic uremic syndrome (Sp-HUS). There have been limi...
journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
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doi:10.1016/s1875-9572(09)60034-6
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journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章,评审
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2010.12.004
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2016.08.005
更新日期:2017-08-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章,评审
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章,随机对照试验
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更新日期:2013-10-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2013.07.008
更新日期:2014-04-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/S1875-9572(09)60016-4
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2011.03.009
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/S1875-9572(08)60014-5
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pub_type: 杂志文章
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2010.12.006
更新日期:2011-02-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章,评审
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更新日期:2017-06-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2015.04.002
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2013.08.001
更新日期:2014-04-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2018.02.002
更新日期:2018-12-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2014.01.002
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2013.01.005
更新日期:2013-08-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
doi:10.1016/j.pedneo.2015.10.008
更新日期:2016-10-01 00:00:00
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journal_title:Pediatrics and neonatology
pub_type: 杂志文章
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