Abstract:
OBJECTIVE:Chronic inflammation has earlier been detected in ruptured intracranial aneurysms. A previous study detected both dental bacterial DNA and bacterial-driven inflammation in ruptured intracranial aneurysm walls. The aim of this study was to compare the presence of oral and pharyngeal bacterial DNA in ruptured and unruptured intracranial aneurysms. The hypothesis was that oral bacterial DNA findings would be more common and the amount of bacterial DNA would be higher in ruptured aneurysm walls than in unruptured aneurysm walls. MATERIALS AND METHODS:A total of 70 ruptured (n = 42) and unruptured (n = 28) intracranial aneurysm specimens were obtained perioperatively in aneurysm clipping operations. Aneurysmal sac tissue was analysed using a real-time quantitative polymerase chain reaction to detect bacterial DNA from several oral species. Both histologically non-atherosclerotic healthy vessel wall obtained from cardiac by-pass operations (LITA) and arterial blood samples obtained from each aneurysm patient were used as control samples. RESULTS:Bacterial DNA was detected in 49/70 (70%) of the specimens. A total of 29/42 (69%) of the ruptured and 20/28 (71%) of the unruptured aneurysm samples contained bacterial DNA of oral origin. Both ruptured and unruptured aneurysm tissue samples contained significantly more bacterial DNA than the LITA control samples (p-values 0.003 and 0.001, respectively). There was no significant difference in the amount of bacterial DNA between the ruptured and unruptured samples. CONCLUSION:Dental bacterial DNA can be found using a quantitative polymerase chain reaction in both ruptured and unruptured aneurysm walls, suggesting that bacterial DNA plays a role in the pathogenesis of cerebral aneurysms in general, rather than only in ruptured aneurysms.
journal_name
Acta Odontol Scandjournal_title
Acta odontologica Scandinavicaauthors
Pyysalo MJ,Pyysalo LM,Pessi T,Karhunen PJ,Lehtimäki T,Oksala N,Öhman JEdoi
10.3109/00016357.2015.1130854subject
Has Abstractpub_date
2016-01-01 00:00:00pages
315-20issue
4eissn
0001-6357issn
1502-3850journal_volume
74pub_type
杂志文章abstract::Overall dental maturity was studied semilongitudinally in a group of 248 healthy children born in Helsinki in 1968-73. In all, 738 orthopantomograms were taken of these children at ages of 2.5-16.5 years. Overall dental maturity was estimated by the method of Demirjian and Goldstein, which is based on the development ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358608997720
更新日期:1986-08-01 00:00:00
abstract::Twenty-seven gold crowns, removed from patients with problems such as diffuse pain and metallic taste, have been examined. The gold crowns were made of an ordinary casting gold alloy, type III. The crowns were built on amalgam cores or big amalgam fillings. Eight of these crowns had cracks beginning at the cervical ma...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358509064134
更新日期:1985-03-01 00:00:00
abstract:OBJECTIVE:Ozone was suggested for treatment of hypersensitive dentin. The purpose of this study was to investigate the effect of ozone, with or without the use of desensitizing agents, on patency and occlusion of simulated hypersensitive dentin. MATERIALS AND METHODS:Sixty standardized dentin slabs were randomly divid...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,随机对照试验
doi:10.3109/00016357.2011.572290
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of age on root resorption and distribution along different parts of the root during prolonged light force application. MATERIAL AND METHODS:Orthodontic appliances were placed in two groups of 30 rats (one group 6 weeks old, the other 9-12 months old), with contralateral sides as con...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350801982522
更新日期:2008-04-01 00:00:00
abstract:OBJECTIVES:(i) To validate caries risk profiles assessed with a computer program against actual caries development in preschool children, (ii) to study the possible impact of a preventive program on the risk profiles, and (iii) to compare the individual risk profiles longitudinally. MATERIAL AND METHODS:Caries risk wa...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350802714734
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To determine if the differing contrast resolution of various LCD monitors affects the reliability or accuracy of measurements of proposed implant sites. MATERIALS AND METHODS:Edentulous areas of human dry skulls were marked with radiopaque markers in order to standardize the plane of the transverse cross-sec...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2012.741709
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To determine chitosan-based chewing gum role on reducing salivary S. mutans counts and salivary pH. MATERIALS AND METHODS:The present double-blind randomised clinical trial with the trial registration number of IRCT20190724044319N1 was conducted on 36 dental students. The volunteers were, randomly, divided i...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2020.1836392
更新日期:2020-11-03 00:00:00
abstract::Errors in questionnaire surveys are usually of one of two sources: non-responses or incorrect answers. The aim was to investigate the validity of a questionnaire survey and to estimate the respective bias of these answers. Of 9,283 subjects selected to receive a questionnaire by post, 3,949 (43%) responded, and, of th...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/000163599428643
更新日期:1999-10-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of storage duration on the tensile bond strength of acrylic and silicone-based denture base materials with liners either heat-cured or auto-cured. MATERIAL AND METHODS:The denture liners investigated were Vertex soft (acrylic-based, heat-cured), Coe soft (acrylic-based, auto-cured),...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350510019667
更新日期:2005-02-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the ultrastructural features of Malassez epithelium (ME) containing protein gene product 9.5 (PGP9.5)-immunoreactive (IR) cells in the cat periodontal ligament (PDL). MATERIAL AND METHODS:Specimens from the teeth and tooth-supporting tissues of four mature cats of both...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350903150002
更新日期:2009-01-01 00:00:00
abstract::Objective: This study evaluated human leucocyte antigen-G gene polymorphisms in patients with periodontitis and healthy controls.Material and methods: The insertion/deletion polymorphism of 14 bp and a single nucleotide polymorphism (SNP) C > G on the position +3142 of the 3' untranslated region of the gene were analy...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2019.1662942
更新日期:2020-03-01 00:00:00
abstract::The adsorption onto silicon oxide surfaces from water and 0.1 M acetate buffer containing 10% parotid saliva at 25 degrees C and 35 degrees C and at pH 6 was monitored in situ using ellipsometry. The silicon oxide surface was used as a model for dental enamel. The adsorption kinetics and the reversibility on rinsing w...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016359109005920
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVE:Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS:This cross-sectional observational study included 120 hospitalized ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.923108
更新日期:2015-05-01 00:00:00
abstract::The orofacial function in 20 children with Down syndrome was evaluated after 4 years of palatal plate therapy in 9 of the children (PPG); the remaining 11 were untreated age-matched controls (CG). All 20 children had received continuous orofacial physical therapy from their speech therapist during the treatment period...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章
doi:10.1080/ode.61.1.39.46
更新日期:2003-02-01 00:00:00
abstract::Bulimia nervosa is increasingly recognized as an eating disorder with significant medical and dental complications, including increased caries rate, thermal hypersensitivity, enamel erosion, xerostomia, and parotid gland hypertrophy. This article reviews the oral manifestations in bulimia nervosa and presents a questi...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章,评审
doi:10.3109/00016359109005929
更新日期:1991-12-01 00:00:00
abstract:OBJECTIVE:To assess the staining susceptibility of four acrylic resin (Ivostar, SR Vivodent PE, Major Dent, Integral) and a nanocomposite resin (Veracia) artificial teeth and to evaluate the stain removal efficacy of denture cleansers. MATERIALS AND METHODS:Sixty maxillary incisors of each brand (total = 300) were div...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.913195
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the presence of symptoms and signs of temporomandibular disorders (TMD) in patients with tinnitus and to evaluate the effect of TMD treatment on tinnitus in a long-term perspective in comparison with a control group of patients on a waiting list. MATERIAL AND METHODS:O...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350500377842
更新日期:2006-04-01 00:00:00
abstract::The aim of the study was to assess the oral health of a group of children, and to compare the findings with the results from an investigation performed 4 years earlier in children of the same age and living in the same area. The material consisted of 149 randomly selected 8-year-old children. The study included examin...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357509026354
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to investigate the prevalence of dental caries in an adult population using four different cross-sectional studies over a 30-year period and to assess its possible associations with socio-economic and socio-behavioural factors. MATERIALS AND METHODS:Four cross-sectional epidemiologi...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2016.1163733
更新日期:2016-07-01 00:00:00
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journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350903117118
更新日期:2009-01-01 00:00:00
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journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358409035248
更新日期:1984-04-01 00:00:00
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journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2015.1087046
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The aim of present study was to determine the effects of conjugated linoleic acid enriched milk on alveolar bone loss, hyperglycaemia, oxidative stress and apoptosis in ligature-induced periodontal disease in diabetic rat model. METHODS:Wistar rats were divided into six experimental groups: 1; non-ligated (N...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2016.1244355
更新日期:2017-01-01 00:00:00
abstract::A 55Fe excited X-ray fluorescence method has been developed for the quantitative nondestructive analysis of Ca content in surface layers of teeth. To eliminate the effects due to curved enamel surface and the localisation of the tooth a special measuring geometry was constructed. The reproducibility of the method rema...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358209041119
更新日期:1982-01-01 00:00:00
abstract:OBJECTIVE:To investigate the gender-related differences in upper airway dimensions and hyoid bone position in Chinese Han children and adolescents (6-18 years) using cone-beam computed tomography (CBCT). MATERIALS AND METHODS:CBCT-scans of 119 boys and 135 girls were selected and divided into four groups (group 1: 6-9...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357.2014.978366
更新日期:2015-07-01 00:00:00
abstract::The enzyme beta-glucuronidase (E.C. 3.2.1.31.) has been studied in developing teeth and bone of Sprague-Dawley rats and Macaque monkeys (Macaca Irus) by means of histochemistry using naphthol-AS-BI-beta-D-glucuronide as substrate and hexazotized pararosanilin as coupling reagent. Since beta-glucuronidase is sensitive ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016357509026357
更新日期:1975-01-01 00:00:00
abstract::Background: Pain in the temporomandibular region is a main complaint causing disability and distress among temporomandibular disorders sufferers.Objectives: The aim of the study was, over an 11-year follow-up on Finnish adult population, to investigate the prevalence of clinically assessed pain-related temporomandibul...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016357.2019.1650955
更新日期:2020-01-01 00:00:00
abstract::It was the purpose of the study to test the efficacy of brushing with a 1% chlorhexidine gel or a commercial solution cleanser (Steradent) in preventing formation of plaque on the fitting surface of new dentures. The study group consisted of 74 denture wearers with denture stomatitis who were assigned randomly to one ...
journal_title:Acta odontologica Scandinavica
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.3109/00016357809027570
更新日期:1978-01-01 00:00:00
abstract:OBJECTIVE:Guided by the conceptual framework of Gilbert and co-workers, this study assesses satisfaction with oral health as reported by 65-year-olds in Sweden and Norway, the relationship of socio-demographic factors, clinical and subjective oral health indicators with satisfaction of oral health, and the consistency ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.1080/00016350902908780
更新日期:2009-01-01 00:00:00
abstract::Symptoms of mandibular dysfunction were followed up longitudinally from the age of 17 to 19 years in 285 adolescents. Totally, 27 subjects dropped out, leaving 258 for the longitudinal intraindividual comparisons. Reports of TMJ sounds increased significantly with age from 14% to 23% for girls, and at 19 years of age ...
journal_title:Acta odontologica Scandinavica
pub_type: 杂志文章
doi:10.3109/00016358609094342
更新日期:1986-12-01 00:00:00