Bacterial DNA findings in ruptured and unruptured intracranial aneurysms.

Abstract:

OBJECTIVE:Chronic inflammation has earlier been detected in ruptured intracranial aneurysms. A previous study detected both dental bacterial DNA and bacterial-driven inflammation in ruptured intracranial aneurysm walls. The aim of this study was to compare the presence of oral and pharyngeal bacterial DNA in ruptured and unruptured intracranial aneurysms. The hypothesis was that oral bacterial DNA findings would be more common and the amount of bacterial DNA would be higher in ruptured aneurysm walls than in unruptured aneurysm walls. MATERIALS AND METHODS:A total of 70 ruptured (n = 42) and unruptured (n = 28) intracranial aneurysm specimens were obtained perioperatively in aneurysm clipping operations. Aneurysmal sac tissue was analysed using a real-time quantitative polymerase chain reaction to detect bacterial DNA from several oral species. Both histologically non-atherosclerotic healthy vessel wall obtained from cardiac by-pass operations (LITA) and arterial blood samples obtained from each aneurysm patient were used as control samples. RESULTS:Bacterial DNA was detected in 49/70 (70%) of the specimens. A total of 29/42 (69%) of the ruptured and 20/28 (71%) of the unruptured aneurysm samples contained bacterial DNA of oral origin. Both ruptured and unruptured aneurysm tissue samples contained significantly more bacterial DNA than the LITA control samples (p-values 0.003 and 0.001, respectively). There was no significant difference in the amount of bacterial DNA between the ruptured and unruptured samples. CONCLUSION:Dental bacterial DNA can be found using a quantitative polymerase chain reaction in both ruptured and unruptured aneurysm walls, suggesting that bacterial DNA plays a role in the pathogenesis of cerebral aneurysms in general, rather than only in ruptured aneurysms.

journal_name

Acta Odontol Scand

authors

Pyysalo MJ,Pyysalo LM,Pessi T,Karhunen PJ,Lehtimäki T,Oksala N,Öhman JE

doi

10.3109/00016357.2015.1130854

subject

Has Abstract

pub_date

2016-01-01 00:00:00

pages

315-20

issue

4

eissn

0001-6357

issn

1502-3850

journal_volume

74

pub_type

杂志文章
  • Dental maturity in Finnish children, estimated from the development of seven permanent mandibular teeth.

    abstract::Overall dental maturity was studied semilongitudinally in a group of 248 healthy children born in Helsinki in 1968-73. In all, 738 orthopantomograms were taken of these children at ages of 2.5-16.5 years. Overall dental maturity was estimated by the method of Demirjian and Goldstein, which is based on the development ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358608997720

    authors: Nyström M,Haataja J,Kataja M,Evälahti M,Peck L,Kleemola-Kujala E

    更新日期:1986-08-01 00:00:00

  • Cracks in gold crowns cemented on amalgam restorations.

    abstract::Twenty-seven gold crowns, removed from patients with problems such as diffuse pain and metallic taste, have been examined. The gold crowns were made of an ordinary casting gold alloy, type III. The crowns were built on amalgam cores or big amalgam fillings. Eight of these crowns had cracks beginning at the cervical ma...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358509064134

    authors: Odén A,Tullberg M

    更新日期:1985-03-01 00:00:00

  • Tubular occlusion of simulated hypersensitive dentin by the combined use of ozone and desensitizing agents.

    abstract:OBJECTIVE:Ozone was suggested for treatment of hypersensitive dentin. The purpose of this study was to investigate the effect of ozone, with or without the use of desensitizing agents, on patency and occlusion of simulated hypersensitive dentin. MATERIALS AND METHODS:Sixty standardized dentin slabs were randomly divid...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/00016357.2011.572290

    authors: Raafat Abdelaziz R,Mosallam RS,Yousry MM

    更新日期:2011-11-01 00:00:00

  • Age-dependent external root resorption during tooth movement in rats.

    abstract:OBJECTIVE:To investigate the effect of age on root resorption and distribution along different parts of the root during prolonged light force application. MATERIAL AND METHODS:Orthodontic appliances were placed in two groups of 30 rats (one group 6 weeks old, the other 9-12 months old), with contralateral sides as con...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350801982522

    authors: Ren Y,Maltha JC,Liem RS,Stokroos I,Kuijpers-Jagtman AM

    更新日期:2008-04-01 00:00:00

  • Validation of an age-modified caries risk assessment program (Cariogram) in preschool children.

    abstract:OBJECTIVES:(i) To validate caries risk profiles assessed with a computer program against actual caries development in preschool children, (ii) to study the possible impact of a preventive program on the risk profiles, and (iii) to compare the individual risk profiles longitudinally. MATERIAL AND METHODS:Caries risk wa...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350802714734

    authors: Holgerson PL,Twetman S,Stecksèn-Blicks C

    更新日期:2009-01-01 00:00:00

  • The validity of different display monitors in the assessment of dental implant site dimensions in cone beam computed tomography images.

    abstract:OBJECTIVE:To determine if the differing contrast resolution of various LCD monitors affects the reliability or accuracy of measurements of proposed implant sites. MATERIALS AND METHODS:Edentulous areas of human dry skulls were marked with radiopaque markers in order to standardize the plane of the transverse cross-sec...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2012.741709

    authors: Al-Ekrish AA,Ekram MI,Al Faleh W,Alkhader M,Al-Sadhan R

    更新日期:2013-09-01 00:00:00

  • Efficacy of chitosan-based chewing gum on reducing salivary S. mutans counts and salivary pH: a randomised clinical trial.

    abstract:OBJECTIVE:To determine chitosan-based chewing gum role on reducing salivary S. mutans counts and salivary pH. MATERIALS AND METHODS:The present double-blind randomised clinical trial with the trial registration number of IRCT20190724044319N1 was conducted on 36 dental students. The volunteers were, randomly, divided i...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016357.2020.1836392

    authors: Khamverdi Z,Farhadian F,Khazaei S,Adabi M

    更新日期:2020-11-03 00:00:00

  • Validity of a questionnaire survey: the role of non-response and incorrect answers.

    abstract::Errors in questionnaire surveys are usually of one of two sources: non-responses or incorrect answers. The aim was to investigate the validity of a questionnaire survey and to estimate the respective bias of these answers. Of 9,283 subjects selected to receive a questionnaire by post, 3,949 (43%) responded, and, of th...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/000163599428643

    authors: Sjöström O,Holst D,Lind SO

    更新日期:1999-10-01 00:00:00

  • Effect of storage duration on tensile bond strength of acrylic or silicone-based soft denture liners to a processed denture base polymer.

    abstract:OBJECTIVE:To investigate the effect of storage duration on the tensile bond strength of acrylic and silicone-based denture base materials with liners either heat-cured or auto-cured. MATERIAL AND METHODS:The denture liners investigated were Vertex soft (acrylic-based, heat-cured), Coe soft (acrylic-based, auto-cured),...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350510019667

    authors: Meşe A,Güzel KG,Uysal E

    更新日期:2005-02-01 00:00:00

  • Epithelial and PGP9.5-immunoreactive cells of Malassez epithelium in the periodontal ligament of cats: a transmission electron microscopic study.

    abstract:OBJECTIVE:The aim of the study was to investigate the ultrastructural features of Malassez epithelium (ME) containing protein gene product 9.5 (PGP9.5)-immunoreactive (IR) cells in the cat periodontal ligament (PDL). MATERIAL AND METHODS:Specimens from the teeth and tooth-supporting tissues of four mature cats of both...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350903150002

    authors: Tadokoro O

    更新日期:2009-01-01 00:00:00

  • Human leukocyte antigen-G polymorphisms in periodontitis.

    abstract::Objective: This study evaluated human leucocyte antigen-G gene polymorphisms in patients with periodontitis and healthy controls.Material and methods: The insertion/deletion polymorphism of 14 bp and a single nucleotide polymorphism (SNP) C > G on the position +3142 of the 3' untranslated region of the gene were analy...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016357.2019.1662942

    authors: Mattuella LG,Bernardi L,Zambra FMB,Campagnaro MB,Oppermann RV,Xavier LL,Chies JAB,Miranda LA

    更新日期:2020-03-01 00:00:00

  • The effect of ionic surfactants on salivary proteins adsorbed on silica surfaces.

    abstract::The adsorption onto silicon oxide surfaces from water and 0.1 M acetate buffer containing 10% parotid saliva at 25 degrees C and 35 degrees C and at pH 6 was monitored in situ using ellipsometry. The silicon oxide surface was used as a model for dental enamel. The adsorption kinetics and the reversibility on rinsing w...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016359109005920

    authors: Arnebrant T,Simonsson T

    更新日期:1991-10-01 00:00:00

  • Antiseptic mouthwashes could worsen xerostomia in patients taking polypharmacy.

    abstract:OBJECTIVE:Polypharmacy is a common cause of xerostomia. This study aimed to investigate whether xerostomia could be an adverse drug event of mouthwashes, when they are used for longer than 2 weeks by patients taking polypharmacy. MATERIALS AND METHODS:This cross-sectional observational study included 120 hospitalized ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2014.923108

    authors: Chevalier M,Sakarovitch C,Precheur I,Lamure J,Pouyssegur-Rougier V

    更新日期:2015-05-01 00:00:00

  • A four-year longitudinal study of palatal plate therapy in children with Down syndrome: effects on oral motor function, articulation and communication preferences.

    abstract::The orofacial function in 20 children with Down syndrome was evaluated after 4 years of palatal plate therapy in 9 of the children (PPG); the remaining 11 were untreated age-matched controls (CG). All 20 children had received continuous orofacial physical therapy from their speech therapist during the treatment period...

    journal_title:Acta odontologica Scandinavica

    pub_type: 临床试验,杂志文章

    doi:10.1080/ode.61.1.39.46

    authors: Carlstedt K,Henningsson G,Dahllöf G

    更新日期:2003-02-01 00:00:00

  • Oral symptoms in bulimia nervosa. A survey of 34 cases.

    abstract::Bulimia nervosa is increasingly recognized as an eating disorder with significant medical and dental complications, including increased caries rate, thermal hypersensitivity, enamel erosion, xerostomia, and parotid gland hypertrophy. This article reviews the oral manifestations in bulimia nervosa and presents a questi...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章,评审

    doi:10.3109/00016359109005929

    authors: Spigset O

    更新日期:1991-12-01 00:00:00

  • Evaluation of staining susceptibility of resin artificial teeth and stain removal efficacy of denture cleansers.

    abstract:OBJECTIVE:To assess the staining susceptibility of four acrylic resin (Ivostar, SR Vivodent PE, Major Dent, Integral) and a nanocomposite resin (Veracia) artificial teeth and to evaluate the stain removal efficacy of denture cleansers. MATERIALS AND METHODS:Sixty maxillary incisors of each brand (total = 300) were div...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2014.913195

    authors: Kurtulmus-Yilmaz S,Deniz ST

    更新日期:2014-11-01 00:00:00

  • Long-term effect on tinnitus by treatment of temporomandibular disorders: a two-year follow-up by questionnaire.

    abstract:OBJECTIVE:The aim of the study was to investigate the presence of symptoms and signs of temporomandibular disorders (TMD) in patients with tinnitus and to evaluate the effect of TMD treatment on tinnitus in a long-term perspective in comparison with a control group of patients on a waiting list. MATERIAL AND METHODS:O...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350500377842

    authors: Tullberg M,Ernberg M

    更新日期:2006-04-01 00:00:00

  • A descriptive and comparative study of oral health in 8-year-old Swedish children.

    abstract::The aim of the study was to assess the oral health of a group of children, and to compare the findings with the results from an investigation performed 4 years earlier in children of the same age and living in the same area. The material consisted of 149 randomly selected 8-year-old children. The study included examin...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357509026354

    authors: Crossner CG,Holm AK

    更新日期:1975-01-01 00:00:00

  • Prevalence of dental caries and influencing factors, time trends over a 30-year period in an adult population. Epidemiological studies between 1983 and 2013 in the county of Dalarna, Sweden.

    abstract:OBJECTIVE:The aim of this study was to investigate the prevalence of dental caries in an adult population using four different cross-sectional studies over a 30-year period and to assess its possible associations with socio-economic and socio-behavioural factors. MATERIALS AND METHODS:Four cross-sectional epidemiologi...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2016.1163733

    authors: Edman K,Öhrn K,Nordström B,Holmlund A

    更新日期:2016-07-01 00:00:00

  • In vivo and in vitro irritation testing of low concentrations of hydrofluoric acid.

    abstract:OBJECTIVE:Acidic fluorides are proposed for the treatment of dental erosion. The aim of this study was to examine the irritation properties of dilute hydrofluoric acid (HF) solutions for potential use in the oral cavity. MATERIAL AND METHODS:Hen's egg test-chorioallantoic membrane (HET-CAM): The CAM was accessed by ca...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350903117118

    authors: Hjortsjö C,Saxegaard E,Young A,Dahl JE

    更新日期:2009-01-01 00:00:00

  • Relevance of social and behavioral factors in the evaluation of dental health care for school children.

    abstract::An interdisciplinary strategy based on a theoretical model for studying dental health was used to analyze the relevance of social and behavioral factors in the evaluation of dental health care for school children. The study comprised pupils who, after a total period of 5 years, differed in their experience with preven...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358409035248

    authors: Hamp SE,Nilsson T,Faresjö T,Gamsäter G

    更新日期:1984-04-01 00:00:00

  • Factors associated with geographic tongue and fissured tongue.

    abstract:OBJECTIVES:The primary objective of this study was to investigate the association of systemic diseases, use of medications, allergies and tobacco habits with geographic tongue (GT) and fissured tongue (FT) lesions. The secondary objectives were to evaluate the clinical characteristics of tongue lesions and to compare t...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2015.1087046

    authors: Dafar A,Çevik-Aras H,Robledo-Sierra J,Mattsson U,Jontell M

    更新日期:2016-01-01 00:00:00

  • The effect of commercial conjugated linoleic acid products on experimental periodontitis and diabetes mellitus in Wistar rats.

    abstract:OBJECTIVE:The aim of present study was to determine the effects of conjugated linoleic acid enriched milk on alveolar bone loss, hyperglycaemia, oxidative stress and apoptosis in ligature-induced periodontal disease in diabetic rat model. METHODS:Wistar rats were divided into six experimental groups: 1; non-ligated (N...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016357.2016.1244355

    authors: Balci Yuce H,Akbulut N,Ocakli S,Kayir O,Elmastas M

    更新日期:2017-01-01 00:00:00

  • A 55Fe excited x-ray fluorescence method for the analysis of Ca content in enamel.

    abstract::A 55Fe excited X-ray fluorescence method has been developed for the quantitative nondestructive analysis of Ca content in surface layers of teeth. To eliminate the effects due to curved enamel surface and the localisation of the tooth a special measuring geometry was constructed. The reproducibility of the method rema...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358209041119

    authors: Olkkonen H,Knuuttila M,Lappalainen R,Sikanen P

    更新日期:1982-01-01 00:00:00

  • Gender-related difference in the upper airway dimensions and hyoid bone position in Chinese Han children and adolescents aged 6-18 years using cone beam computed tomography.

    abstract:OBJECTIVE:To investigate the gender-related differences in upper airway dimensions and hyoid bone position in Chinese Han children and adolescents (6-18 years) using cone-beam computed tomography (CBCT). MATERIALS AND METHODS:CBCT-scans of 119 boys and 135 girls were selected and divided into four groups (group 1: 6-9...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357.2014.978366

    authors: Jiang YY,Xu X,Su HL,Liu DX

    更新日期:2015-07-01 00:00:00

  • Histochemical studies on beta-glucuronidase activity in developing teeth and bone of rat and Macaque monkey.

    abstract::The enzyme beta-glucuronidase (E.C. 3.2.1.31.) has been studied in developing teeth and bone of Sprague-Dawley rats and Macaque monkeys (Macaca Irus) by means of histochemistry using naphthol-AS-BI-beta-D-glucuronide as substrate and hexazotized pararosanilin as coupling reagent. Since beta-glucuronidase is sensitive ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016357509026357

    authors: Hasselgren G,Hammarström LE

    更新日期:1975-01-01 00:00:00

  • Factors associated with signs of temporomandibular pain: an 11-year-follow-up study on Finnish adults.

    abstract::Background: Pain in the temporomandibular region is a main complaint causing disability and distress among temporomandibular disorders sufferers.Objectives: The aim of the study was, over an 11-year follow-up on Finnish adult population, to investigate the prevalence of clinically assessed pain-related temporomandibul...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016357.2019.1650955

    authors: Banafa A,Suominen AL,Sipilä K

    更新日期:2020-01-01 00:00:00

  • Chlorhexidine gel and Steradent employed in cleaning dentures.

    abstract::It was the purpose of the study to test the efficacy of brushing with a 1% chlorhexidine gel or a commercial solution cleanser (Steradent) in preventing formation of plaque on the fitting surface of new dentures. The study group consisted of 74 denture wearers with denture stomatitis who were assigned randomly to one ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3109/00016357809027570

    authors: Budtz-Jørgensen E,Milton Knudsen A

    更新日期:1978-01-01 00:00:00

  • Variation in subjective oral health indicators of 65-year-olds in Norway and Sweden.

    abstract:OBJECTIVE:Guided by the conceptual framework of Gilbert and co-workers, this study assesses satisfaction with oral health as reported by 65-year-olds in Sweden and Norway, the relationship of socio-demographic factors, clinical and subjective oral health indicators with satisfaction of oral health, and the consistency ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.1080/00016350902908780

    authors: Ekbäck G,Astrøm AN,Klock K,Ordell S,Unell L

    更新日期:2009-01-01 00:00:00

  • Two-year longitudinal study of symptoms of mandibular dysfunction in adolescents.

    abstract::Symptoms of mandibular dysfunction were followed up longitudinally from the age of 17 to 19 years in 285 adolescents. Totally, 27 subjects dropped out, leaving 258 for the longitudinal intraindividual comparisons. Reports of TMJ sounds increased significantly with age from 14% to 23% for girls, and at 19 years of age ...

    journal_title:Acta odontologica Scandinavica

    pub_type: 杂志文章

    doi:10.3109/00016358609094342

    authors: Wänman A,Agerberg G

    更新日期:1986-12-01 00:00:00