Sensitivity analysis of the position of the intervertebral centres of reaction in upright standing--a musculoskeletal model investigation of the lumbar spine.

Abstract:

:The loads between adjacent vertebrae can be generalised as a single spatial force acting at the intervertebral centre of reaction. The exact position in vivo is unknown. However, in rigid body musculoskeletal models that simulate upright standing, the position is generally assumed to be located at the discs' centres of rotation. The influence of the antero-posterior position of the centre of reaction on muscle activity and joint loads remains unknown. Thus, by using an inverse dynamic model, we varied the position of the centre of reaction at L4/L5 (i), simultaneously at all lumbar levels (ii), and by optimisation at all lumbar levels (iii). Variation of the centres of reaction can considerably influence the activities of lumbar muscles and the joint forces between vertebrae. The optimisation of the position of the centre of reaction reduced the maximum lumbar muscle activity and axial joint forces at L4/L5 from 17.5% to 1.5% of the muscle strength and from 490 N to 390 N, respectively. Thus, when studying individual postures, such as for therapeutic or preventive evaluations, potential differences between the centre of reaction and the centre of rotation might influence the study results. These differences could be taken into account by sensitivity analyses.

journal_name

Med Eng Phys

authors

Zander T,Dreischarf M,Schmidt H

doi

10.1016/j.medengphy.2015.12.003

subject

Has Abstract

pub_date

2016-03-01 00:00:00

pages

297-301

issue

3

eissn

1350-4533

issn

1873-4030

pii

S1350-4533(15)00282-9

journal_volume

38

pub_type

杂志文章
  • TETRA mobile radios interfere with electroencephalography recording equipment.

    abstract::We observed an anomaly in the human electroencephalogram (EEG) associated with exposure to terrestrial trunked radio (TETRA) Radiofrequency Fields (RF). Here, we characterize the time and frequency components of the anomaly and demonstrate that it is an artefact caused by TETRA RF interfering with the EEG recording eq...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2013.04.009

    authors: Fouquet NC,Hawken MB,Elliott P,Burgess AP

    更新日期:2013-11-01 00:00:00

  • Stress free configuration of the human eye.

    abstract::Numerical simulations of eye globes often rely on topographies that have been measured in vivo using devices such as the Pentacam or OCT. The topographies, which represent the form of the already stressed eye under the existing intraocular pressure, introduce approximations in the analysis. The accuracy of the simulat...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2012.09.006

    authors: Elsheikh A,Whitford C,Hamarashid R,Kassem W,Joda A,Büchler P

    更新日期:2013-02-01 00:00:00

  • Simulations to study spatial extent of stimulation and effect of electrode-tissue gap in subretinal implants.

    abstract::We present a finite element based simulation and analysis method to describe the spatial extent of stimulation and the effects of electrode-tissue interactions in subretinal prostheses. In particular, we estimate the threshold stimulation current needed to depolarise and evoke action potentials in the ganglion cells t...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2011.01.015

    authors: Kasi H,Bertsch A,Guyomard JL,Kolomiets B,Picaud S,Pelizzone M,Renaud P

    更新日期:2011-07-01 00:00:00

  • Envelopment filter and K-means for the detection of QRS waveforms in electrocardiogram.

    abstract::The electrocardiogram (ECG) is a well-established technique for determining the electrical activity of the heart and studying its diseases. One of the most common pieces of information that can be read from the ECG is the heart rate (HR) through the detection of its most prominent feature: the QRS complex. This paper ...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2015.03.019

    authors: Merino M,Gómez IM,Molina AJ

    更新日期:2015-06-01 00:00:00

  • An investigation to determine if a single validated density-elasticity relationship can be used for subject specific finite element analyses of human long bones.

    abstract::Subject-specific FE-models of human long bones have to predict mechanical parameters with sufficient accuracy to be applicable in a clinical setting. One of the main aspects in subject-specific FE-models of bones regarding accuracy is the modeling of the material inhomogeneity. The goal of this study was therefore to ...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2012.08.022

    authors: Eberle S,Göttlinger M,Augat P

    更新日期:2013-07-01 00:00:00

  • Extended Central Tendency Measure and difference plot for heart rate variability analysis.

    abstract::Heart rate variability (HRV) is a non-invasive alternative to analyze the role of the autonomic nervous system (ANS) on heart functioning. Many tools have been developed to analyze collected cardiac data. Among them, the Central Tendency Measure (CTM) is a quantitative method for variability analysis of RR intervals. ...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2019.09.024

    authors: Belfort RAU,Treccossi SPC,Silva JLF,Pillat VG,Freitas CBN,Dos Santos L

    更新日期:2019-12-01 00:00:00

  • Mechanical performance of Anatomic-Functional-Geometry dental treatments: A computational study.

    abstract::In this paper the biomechanical response of a novel dental preparation technique, referred to as the Anatomic-Functional-Geometry treatment (AFG), is investigated through a 3D nonlinear finite-element modelling approach. A comparative investigation against a standard technique employed in dental clinical practice is c...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2020.10.016

    authors: Gaziano P,Lorenzi C,Bianchi D,Monaldo E,Dolci A,Vairo G

    更新日期:2020-12-01 00:00:00

  • Biomechanical and histological evaluation of abdominal wall compliance with intraperitoneal onlay mesh implants in rabbits: a comparison of six different state-of-the-art meshes.

    abstract:BACKGROUND:An ideal prosthetic mesh for incisional hernia repair should mimic the anisotropic compliance of the abdominal wall, and at lower loads should exhibit higher distensibility without impairment of safety at higher loads. This study evaluated the biomechanical properties of six meshes in a rabbit model. METHOD...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2011.09.022

    authors: Konerding MA,Chantereau P,Delventhal V,Holste JL,Ackermann M

    更新日期:2012-09-01 00:00:00

  • In vivo estimation of normal left ventricular stiffness and contractility based on routine cine MR acquisition.

    abstract::Post-myocardial infarction remodeling process is known to alter the mechanical properties of the heart. Biomechanical parameters, such as tissue stiffness and contractility, would be useful for clinicians to better assess the severity of the diseased heart. However, these parameters are difficult to obtain in the curr...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2020.09.003

    authors: Rumindo GK,Ohayon J,Croisille P,Clarysse P

    更新日期:2020-11-01 00:00:00

  • Effects of cartilage rings on airflow and particle deposition in the trachea and main bronchi.

    abstract::In most computational fluid dynamic (CFD) analysis of the human lung, it has been assumed that the trachea and branches of the lung have smooth walls. In order to determine if this is a valid assumption, the effects of cartilage rings on airflow and particle deposition in the lungs was determined through conducting si...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2007.06.010

    authors: Russo J,Robinson R,Oldham MJ

    更新日期:2008-06-01 00:00:00

  • Development of a small wireless device for perspiration monitoring.

    abstract::A small and wireless device that can capture the temporal pattern of perspiration by a novel structure of water vapor collection combined with reusable desiccant has been developed. The novel device consists of a small cylindrical case with a temperature/relative humidity sensor, battery-driven data logger, and silica...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2015.12.009

    authors: Ogai K,Fukuoka M,Kitamura K,Uchide K,Nemoto T

    更新日期:2016-04-01 00:00:00

  • Toward verified and validated FE simulations of a femur with a cemented hip prosthesis.

    abstract:BACKGROUND:Verified and validated CT-based high-order finite element (FE) methods were developed that predict accurately the mechanical response of patient-specific intact femurs. Here we extend these capabilities to human femurs undergoing a total hip replacement using cemented prostheses. METHODS:A fresh-frozen huma...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2012.09.007

    authors: Yosibash Z,Katz A,Milgrom C

    更新日期:2013-07-01 00:00:00

  • A method of examining the magnitude and origin of "soft" and "hard" tissue forces resisting limb lengthening.

    abstract::Complications arising from limb-lengthening procedures such as muscle contracture, axial malalignment of the bone and traction injuries to the nerves and vessels, are often severe. Often complications arise from the build-up of forces in the biological tissues which are resisting lengthening. Little is known about the...

    journal_title:Medical engineering & physics

    pub_type: 临床试验,杂志文章

    doi:10.1016/s1350-4533(97)00010-6

    authors: Gardner TN,Evans M,Simpson AH,Kyberd PJ,Kenwright J

    更新日期:1997-07-01 00:00:00

  • A non-invasive Cochlear Microphonic measurement system.

    abstract::The Cochlear Microphonic is one of the electrical potentials generated by the ear in response to audible stimuli. It is very difficult to measure the CM non-invasively because it has a very small magnitude (less than 1 μV). A high Common Mode Rejection Ratio (CMRR) and very large bandwidth (5 Hz-20 kHz) biomedical amp...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2012.06.017

    authors: Masood A,Teal PD,Hollitt C

    更新日期:2012-10-01 00:00:00

  • Multispectral characterization of tissues encountered during laparoscopic colorectal surgery.

    abstract:AIMS:This study investigated the feasibility of automated differentiation between essential tissue types encountered during laparoscopic colorectal surgery using spectral analysis. METHODS:Wide band (440-1830 nm) spectra were collected using an optical fiber probe and spectrometer from freshly explanted, ex vivo, huma...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2013.01.004

    authors: Schols RM,Dunias P,Wieringa FP,Stassen LP

    更新日期:2013-07-01 00:00:00

  • Time-dependent analysis of leaflets in mechanical aortic bileaflet heart valves in closing phase using the finite strip method.

    abstract:BACKGROUND AND AIMS OF THE STUDY:Mechanical heart valves (MHV) are widely used to replace dysfunctional and failed heart valves. The bileaflet MHV design is very popular due to its superior hemodynamics. Since their introduction in 1977, the hemodynamics of bileaflet prostheses has been extensively studied. In this stu...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2005.03.013

    authors: Mohammadi H,Ahmadian MT,Wan WK

    更新日期:2006-03-01 00:00:00

  • Validation of computerized square-drawing based evaluation of motor function in patients with stroke.

    abstract::Human-administered clinical scales are commonly used for quantifying motor performance and determining the course of therapy in post-stroke individuals. Computerized methods aim to improve consistency, resolution and duration of patients' evaluation. The objective of this study was to test the validity of computerized...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2019.06.001

    authors: Isaković MS,Savić AM,Konstantinović LM,Popović MB

    更新日期:2019-09-01 00:00:00

  • Can subject-specific single-fibre electrically evoked auditory brainstem response data be predicted from a model?

    abstract::This article investigates whether prediction of subject-specific physiological data is viable through an individualised computational model of a cochlear implant. Subject-specific predictions could be particularly useful to assess and quantify the peripheral factors that cause inter-subject variations in perception. T...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2012.09.001

    authors: Malherbe TK,Hanekom T,Hanekom JJ

    更新日期:2013-07-01 00:00:00

  • Measurement of the chondrocyte membrane permeability to Me2SO, glycerol and 1,2-propanediol.

    abstract::The addition of cryopreservative agents (CPAs) to chondrocytes and natural and engineered cartilage is critical to protect the cells and tissues from freezing damage during cryopreservation, but this may cause cell damage, e.g. by osmotic shock. The damage could be minimized by the control of the cell volume excursion...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/s1350-4533(03)00073-0

    authors: Xu X,Cui Z,Urban JP

    更新日期:2003-09-01 00:00:00

  • Finite element analysis of side branch access during bifurcation stenting.

    abstract::Stent implantation has become a widely accepted endovascular intervention for the treatment of stenosed arteries. This minimally invasive technique has shown excellent results in unbranched arteries. However, stenting bifurcation lesions remains a challenge in coronary intervention as it is associated with a lower suc...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2008.11.013

    authors: Mortier P,De Beule M,Van Loo D,Verhegghe B,Verdonck P

    更新日期:2009-05-01 00:00:00

  • In vitro model of intravenous fluid administration: analysis of vein resistance to rapid fluid delivery.

    abstract::Rapid fluid administration is the cornerstone of successful trauma resuscitation of patients in a state of shock. Intravenous (IV) fluid delivery is a physical intrusion into a vein which results in a complex interaction between the rigid catheter and the compliant vein. We present an experimental model of IV infusion...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/s1350-4533(00)00046-1

    authors: Yaniv S,Halpern P,Aladgem D,Zaretsky U,Elad D

    更新日期:2000-07-01 00:00:00

  • Current development in non-invasive glucose monitoring.

    abstract::Painless control of blood glycemic levels could improve life quality of diabetes patients, enabling a better regulation of hyper- and hypoglycaemia episodes and thereby avoiding physiological complications. Although research groups have been trying for decades to separate non-invasive glucose information from interfer...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章,评审

    doi:10.1016/j.medengphy.2007.06.003

    authors: Ferrante do Amaral CE,Wolf B

    更新日期:2008-06-01 00:00:00

  • Assessment of four statistical pattern recognition techniques to assist in obstructive sleep apnoea diagnosis from nocturnal oximetry.

    abstract::The aim of this study is to assess the utility of traditional statistical pattern recognition techniques to help in obstructive sleep apnoea (OSA) diagnosis. Classifiers based on quadratic (QDA) and linear (LDA) discriminant analysis, K-nearest neighbours (KNN) and logistic regression (LR) were evaluated. Spectral and...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2009.05.010

    authors: Marcos JV,Hornero R,Alvarez D,del Campo F,Zamarrón C

    更新日期:2009-10-01 00:00:00

  • Regression-based indices of fatigue in paraplegics' electrically stimulated quadriceps.

    abstract::We studied muscle fatigue in 19 paraplegic patients during an isometric sustained contraction. Both quadriceps (n = 38) were maximally stimulated for 126 s. We defined a nonlinear equation with four coefficients to fit the data and extract fatigue indices carrying information on the amount (asymptotic values, torque c...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/s1350-4533(97)00038-6

    authors: Rabischong E,Chavet P

    更新日期:1997-12-01 00:00:00

  • Robust infrarenal aortic aneurysm lumen centerline detection for rupture status classification.

    abstract::The objective of this work is to develop a robust method for human abdominal aortic aneurysm (AAA) centerline detection that can contribute to the accurate computation of features for the prediction of AAA rupture risk. A semiautomatic algorithm is proposed for detecting the lumen centerline in contrast-enhanced abdom...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2013.03.005

    authors: Zhang H,Kheyfets VO,Finol EA

    更新日期:2013-09-01 00:00:00

  • Comparison of virtual and real electric powered wheelchair driving using a position sensing joystick and an isometric joystick.

    abstract::There are limited interface options for electric powered wheelchairs, which results in the inability of some individuals to drive independently. In addition, the development of new interface technologies will necessitate the development of alternative training methods. This study compares a conventional position sensi...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/s1350-4533(02)00111-x

    authors: Cooper RA,Spaeth DM,Jones DK,Boninger ML,Fitzgerald SG,Guo S

    更新日期:2002-12-01 00:00:00

  • Intramedullary femoral nails: one or two lag screws? A preliminary study.

    abstract::Failures of proximal femoral nails that treat unstable femoral fractures have been reported. In this communication, a finite element model to include a proximal femoral nail within a fractured femur was used to carry out preliminary investigations into configurations of single or double lag screws. The effects of the ...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/s1350-4533(00)00081-3

    authors: Wang CJ,Brown CJ,Yettram AL,Procter P

    更新日期:2000-11-01 00:00:00

  • Finite element prediction of surface strain and fracture strength at the distal radius.

    abstract::To better understand the mechanisms underlying distal radius fracture we have developed finite element models to predict radius bone strain and fracture strength under loading conditions simulating a fall. This study compares experimental surface strains and fracture loads of the distal radius with specimen-specific f...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2011.07.016

    authors: Edwards WB,Troy KL

    更新日期:2012-04-01 00:00:00

  • An impedance sensor to monitor and control cerebral ventricular volume.

    abstract::This paper presents a sensor for monitoring and controlling the volume of the cerebrospinal fluid-filled ventricles of the brain. The measurement principle of the sensor exploits electrical conductivity differences between the cerebrospinal fluid and the brain tissue. The electrical contrast was validated using dog br...

    journal_title:Medical engineering & physics

    pub_type: 杂志文章

    doi:10.1016/j.medengphy.2009.03.011

    authors: Linninger A,Basati S,Dawe R,Penn R

    更新日期:2009-09-01 00:00:00

  • Effect of different inertial parameter sets on joint moment calculation during stair ascending and descending.

    abstract::The reliability of internal joint moment calculation in gait analysis during daily living activities is fundamental for clinical decisions based on joint function. This calculation, obtained by means of the inverse dynamics, depends on several modelling factors, such as assumptions on the segments and on the relevant ...

    journal_title:Medical engineering & physics

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.medengphy.2004.12.002

    authors: Fantozzi S,Stagni R,Cappello A,Leardini A

    更新日期:2005-07-01 00:00:00