Family Aggregation of HTLV-1 Infection Associated with FAS -670A/G Polymorphism: A Case Report.

Abstract:

:Human T-lymphotropic virus 1 (HTLV-1) infection has been associated with ATL and inflammatory diseases but remains a neglected health problem. HTLV-1 associated diseases were originally described as sporadic entities, but family aggregations have been reported. Viral, genetic, immunological and behavioral factors were used to explain family clusters, but until now a clear explanation remains uncertain. In the present study we report, for the first time, a family cluster of diseased persons presenting the infection across three generations associated with FAS -670A/G polymorphism.

journal_name

Front Microbiol

authors

Vallinoto ACR,Santana BB,Queiroz MAF,da Silva ANMR,Cayres-Vallinoto IMV,da Costa CA,de Sousa MS,Ishak R

doi

10.3389/fmicb.2017.02685

subject

Has Abstract

pub_date

2018-01-15 00:00:00

pages

2685

issn

1664-302X

journal_volume

8

pub_type

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