Abstract：
PURPOSE:Hereditary spastic paraplegia (HSP) and hereditary spastic ataxia (HSA) are a heterogeneous group of genetic disorders characterized by progressive lower limb spasticity resulting from pyramidal tract dysfunction. By identifying critical imaging findings within the clinical context of spasticity, radiologists are uniquely positioned to recommend specific genetic testing, and thus facilitate diagnosis. METHODS:We present two examples of HSP and HSA that had gone clinically unrecognized for years, and in which magnetic resonance imaging played a critical role in the diagnosis. RESULTS:Radiologists' awareness of HSP and HSA, combined with a critical review of the clinical history and characteristic imaging findings led to specific genetic testing and a definitive diagnosis. CONCLUSION:Awareness of HSP and HSA among radiologists will expedite more accurate diagnosis, explanation of patient symptoms, recommendation for syndrome-specific treatment, and family planning considerations.
journal_name
Clin Neuroradioljournal_title
Clinical neuroradiologyauthors
Wagner F,Titelbaum DS,Engisch R,Coskun EK,Waugh JLdoi
10.1007/s00062-018-0665-5subject
Has Abstractpub_date
2019-06-01 00:00:00pages
215-221issue
2eissn
1869-1439issn
1869-1447pii
10.1007/s00062-018-0665-5journal_volume
29pub_type
杂志文章abstract：PURPOSE:The three-dimensional digital subtraction angiography (3D DSA) technique is the current standard and is based on both mask and fill runs to enable the subtraction technique. Artificial intelligence (AI)-based 3D angiography (3DA) was developed to reduce radiation dosage because only one contrast-enhanced run of...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-019-00836-7
更新日期：2020-12-01 00:00:00
abstract：:The technology available for the endovascular treatment of intracranial aneurysms is rapidly evolving. Both current and future devices are described. This includes, among others, UNO for parent vessel occlusion, the Medina device for saccular filling, the Comaneci device for remodeling, pCONus for assisted coil occlus...
journal_title：Clinical neuroradiology
pub_type： 杂志文章,评审
doi：10.1007/s00062-015-0403-1
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:Against the background of the increasing dilemma in the scientific community regarding protected versus unprotected carotid artery stent (CAS) placement and the disputed points in interpreting the results of scientific studies as well as the difficulty in conducting such randomized controlled studies, this arti...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-011-0057-6
更新日期：2011-06-01 00:00:00
abstract：BACKGROUND:Temporary balloon test occlusion (BTO) might be performed prior to procedures in which occlusion of the internal carotid artery (ICA) might be necessary. We tested the hypothesis that parametric color coding (PCC) of angiographic series (digital subtraction angiography (DSA)) along with the assessment of cer...
journal_title：Clinical neuroradiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00062-013-0208-z
更新日期：2013-12-01 00:00:00
abstract：PURPOSE:The aim of this study was to compare the diagnostic accuracy of 3D time-of-flight (TOF-MRA) and contrast-enhanced (CE-MRA) magnetic resonance angiography at 3 T for detection and quantification of proximal high-grade stenosis using multidetector computed tomography angiography (MDCTA) as reference standard. ME...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-013-0279-x
更新日期：2015-03-01 00:00:00
abstract：PURPOSE:Since the incidental discovery and systematic introduction of mechanical endovascular stroke treatment in 2015 there are few reports about the real-life situation in daily clinical practice. The aim of this study was to evaluate the mechanical thrombectomy data documented in the quality assurance database of th...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-020-00989-w
更新日期：2021-01-22 00:00:00
abstract：:Temporal bone microanatomy is a common source of consternation for radiologists. Serpentine foramina, branching cranial nerves, and bony canals containing often clinically relevant but often miniscule arterial branches may all cause confusion, even among radiologists familiar with temporal bone imaging. In some cases,...
journal_title：Clinical neuroradiology
pub_type： 杂志文章,评审
doi：10.1007/s00062-019-00864-3
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:Knowledge about the localization and outcome of iatrogenic dissection (ID) during endovascular treatment of acute ischemic stroke (AIS) is limited. We aimed to determine the frequency, clinical aspects and morphology of ID in endovascular AIS treatment and to identify predictors of this complication. METHODS:D...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-017-0639-z
更新日期：2019-03-01 00:00:00
abstract：PURPOSE:Evaluation of a new postprocessing method for postoperative control of cochlear implants (CI) based on a single flat detector computed tomography (FD-CT) run and volume rendering of 3D models of the inner ear. METHODS:The FD-CT datasets of CIs were selected and postprocessed to generate both standard multiplan...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-019-00832-x
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:The aim of this study was to analyze sex differences in outcome after thrombectomy for acute ischemic stroke in clinical practice in a large prospective multicenter registry. METHODS:Data of consecutive stroke patients treated with thrombectomy (June 2015-April 2018) derived from an industry-independent regist...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-020-00983-2
更新日期：2020-12-21 00:00:00
abstract：PURPOSE:Claustrophobic reactions in patients undergoing magnetic resonance imaging (MRI) have a significant impact on the workflow, patient acceptance and ultimately the costs involved in obtaining a diagnostic scan. The purpose of this study was to determine if the use of a wide, short bore MRI scanner could reduce th...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-011-0075-4
更新日期：2011-09-01 00:00:00
abstract：PURPOSE:The aim of this study was a comparison of the diagnostic value of time-of-flight magnetic resonance angiography (TOF-MRA) and contrast-enhanced (CE) MRA in the setting of acute stroke MRI. The hypothesis was that CE-MRA has at least the same diagnostic value as the commonly used TOF-MRA. MATERIALS AND METHODS:...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-010-0039-0
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:Our aim was to identify imaging characteristics of pilocytic astrocytomas (PAs) in the cerebral ventricles to help radiologists distinguish PAs from other brain tumors preoperatively. METHODS:Twelve postsurgery patients with a pathological PA diagnosis were included. Among them, 10 had submitted to surgery bas...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-015-0370-6
更新日期：2016-09-01 00:00:00
abstract：PURPOSE:Isolated posterior inferior cerebellar artery dissecting aneurysms are rare lesions. Their underlying pathology, presentation, and natural history are poorly understood. Their treatment is controversial, and few data are available regarding the best treatment. We conducted the first study comparing selective co...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-013-0247-5
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Distal embolization or movement of the thrombus to previously uninvolved vasculature are feared complications during stroke thrombectomy. We looked at associated factors in a consecutive series of patients who underwent thrombectomy with the same endovascular device. METHODS:We included all patients with ac...
journal_title：Clinical neuroradiology
pub_type： 杂志文章,评审
doi：10.1007/s00062-018-0679-z
更新日期：2019-09-01 00:00:00
abstract：PURPOSE:Patients with transient global amnesia (TGA) present with a characteristic clinical syndrome although other differential diagnoses have to be considered. Diffusion-weighted imaging (DWI) represents a highly specific diagnostic tool in the context of TGA; however, standard clinical DWI often fails to detect the ...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-012-0140-7
更新日期：2012-12-01 00:00:00
abstract：PURPOSE:Stroke is a rising cause of mortality in human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) populations. The etiology of stroke remains at the core of the decision-making process to treat and prevent recurrent events. In this population HIV vasculopathy (HIV-V) and varicella zoster...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-011-0087-0
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND AND PURPOSE:Several studies have shown that thrombectomy is safe and effective in occlusions of the M2 segment of the middle cerebral artery. This retrospective study compared superior and inferior division occlusions regarding radiological and clinical outcomes. METHODS:Between 2009 and 2017, patients trea...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-019-00767-3
更新日期：2020-06-01 00:00:00
abstract：PURPOSE:The aim of the study was to examine the effects of mechanical thrombectomy using the Solitaire stent in patients with thromboembolic occlusions of the intracranial carotid artery bifurcation (carotid T) or middle cerebral artery (MCA) and to compare the results with a historical cohort treated with local intraa...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-011-0099-9
更新日期：2012-06-01 00:00:00
abstract：PURPOSE:Computed tomography (CT) accounts for more than half of the total radiation exposure from medical procedures, which makes dose reduction in CT an effective means of reducing radiation exposure. We analysed the dose reduction that can be achieved with a new CT scanner [Somatom Edge (E)] that incorporates new dev...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-013-0263-5
更新日期：2014-03-01 00:00:00
abstract：PURPOSE:Acute major stroke with high-grade stenosis or occlusion of the extracranial internal carotid artery (ICA) and additional intracranial large artery occlusion is increasingly treated with a mechanical endovascular approach by extracranial stenting and intracranial thrombectomy due to poor response to systemic th...
journal_title：Clinical neuroradiology
pub_type： 临床试验,杂志文章
doi：10.1007/s00062-014-0318-2
更新日期：2015-12-01 00:00:00
abstract：PURPOSE:Little is known about catheter-based endovascular treatment of vertebrobasilar artery branch occlusion (VEBABO) in acute ischemic stroke (AIS). Nonetheless, the experience of mechanical thrombectomy (MT) in distal small sized arteries of the anterior circulation seems promising in AIS. In this multicenter study...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-020-00970-7
更新日期：2020-10-27 00:00:00
abstract：PURPOSE:Visualization of the abducens nerve in its petroclival segment still remains challenging. We aimed to investigate the detectability of the petroclival segment of the abducens nerve and to evaluate the role of the size of the petroclival venous confluence (PVC) in the visibility of the nerve using contrast-enhan...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-015-0415-x
更新日期：2017-03-01 00:00:00
abstract：PURPOSE:Angiographic assessment of carotid cavernous fistulas (CCFs) can be complex. Our purpose was to examine whether the use of parametric color coding in the postprocessing of DSA series is advantageous in the evaluation of CCFs. METHODS:We enrolled 16 patients with angiographically proven CCFs. Endovascular treat...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-012-0184-8
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:The low-profile Acandis Acclino is a self-expandable nitinol microstent for stent-assisted coiling of intracranial aneurysms. This article reports long-term clinical and angiographic outcome in a multicenter setting. METHODS:In this study 98 consecutive patients (mean age 55.4 ± 13.5 years) were treated with t...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-019-00847-4
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Primary spinal extradural Ewing's sarcoma (PSEES) or primitive neuroectodermal tumor (PNET) is uncommon. The present study summarizes the magnetic resonance (MR) imaging appearance of PSEES. METHODS:Literature search from 1994 to 2012 with our representative case presentation. RESULTS:Twenty-one patients, 12 ...
journal_title：Clinical neuroradiology
pub_type： 杂志文章,评审
doi：10.1007/s00062-013-0222-1
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:Diagnosis of cortical vein thrombosis (CVT) on the basis of clot hyperintensity on diffusion-weighted imaging (DWI) has been reported as limited. Our aim was to evaluate different DWI findings of CVT either in isolated form or in combination with sinus thrombosis. METHODS:In this review-board-approved study, p...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-014-0301-y
更新日期：2015-09-01 00:00:00
abstract：PURPOSE:We aimed to compare images obtained with an Enhanced 3D multi-echo GRE T2*-weighted angiography (ESWAN) sequence with those obtained with a susceptibility-weighted imaging-spoiled gradient-recalled echo (SWI-SPGR) sequence and a two-dimensional (2D) T2*-weighted gradient-recalled echo (GRE) sequence for the des...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-012-0185-7
更新日期：2013-06-01 00:00:00
abstract：OBJECT:The anterior choroidal artery (AChoA) is a rare location for intracranial aneurysms. The treatment of these aneurysms may be challenging due to the risk of occlusion of such a small and eloquent artery as the AChoA. We aimed to evaluate the risk factors for complications in AChoA aneurysm treatment. METHODS:We ...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-017-0575-y
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To illustrate the added value of flat-detector computed tomography angiography with intravenous contrast media injection (intravenous FDCTA) in the evaluation of complex A1/A2/AcomA aneurysms. PATIENTS AND METHODS:We retrospectively reviewed 15 patients with ruptured aneurysms. In each patient, an intravenou...
journal_title：Clinical neuroradiology
pub_type： 杂志文章
doi：10.1007/s00062-017-0592-x
更新日期：2018-12-01 00:00:00
