Abstract：
:It has been debated whether orientation selectivity in mouse primary visual cortex (V1) is derived from tuned lateral geniculate nucleus (LGN) inputs or computed from untuned LGN inputs. However, few studies have measured orientation tuning of LGN axons projecting to V1. We measured the response properties of mouse LGN axons terminating in V1 and found that LGN axons projecting to layer 4 were generally less tuned for orientation than axons projecting to more superficial layers of V1. We also found several differences in response properties between LGN axons and V1 neurons in layer 4. These results suggest that orientation selectivity of mouse V1 may not simply be inherited from LGN inputs, but could also depend on thalamocortical or V1 circuits.
journal_name
Nat Neuroscijournal_title
Nature neuroscienceauthors
Kondo S,Ohki Kdoi
10.1038/nn.4215subject
Has Abstractpub_date
2016-02-01 00:00:00pages
316-9issue
2eissn
1097-6256issn
1546-1726pii
nn.4215journal_volume
19pub_type
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