Abstract:
OBJECTIVE:To quantify the number of personnel, time to induce and complete sedation using propofol for outpatient magnetic resonance imaging (MRI) of the brain, and the frequency of serious adverse events (SAEs) in children with autism spectrum disorder (ASD) compared with children without ASD. RESULTS:Baseline characteristics were the same between both groups. Overall sedation success was 99%. Although most children were sedated with ≤3 providers, 10% with ASD needed ≥4 providers (P = .005). The duration of sedation was less for the ASD group compared with the non-ASD group (49 minutes vs 56 minutes, P = .005). There was no difference in SAE frequency between groups (ASD 14% vs non-ASD 16%, P = .57). CONCLUSION:Children with ASD can be sedated for brain MRI using propofol with no increased frequency of SAEs compared with children without ASD. Sedation teams should anticipate that 10% of children with ASD may need additional personnel before propofol induction.
journal_name
J Child Neuroljournal_title
Journal of child neurologyauthors
Kamat PP,Karaga MK,Wisniewski BL,McCracken CE,Simon HK,Sidhu R,Grunwell JRdoi
10.1177/0883073817753908subject
Has Abstractpub_date
2018-04-01 00:00:00pages
313-319issue
5eissn
0883-0738issn
1708-8283journal_volume
33pub_type
杂志文章abstract::Neuroblastoma is, at once, the most common and deadly extracranial solid tumor of childhood. Efforts aimed at targeting the neural characteristics of these tumors have taught us much about neural crest cell biology, apoptosis induction in the nervous system, and neurotrophin receptor signaling and intracellular proces...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/0883073813483173
更新日期:2013-06-01 00:00:00
abstract::Subacute sclerosing panencephalitis (SSPE) typically presents with progressive mental deterioration, behavioral changes, and myoclonic jerks. Atypical presentations are not unknown and may result in diagnostic delays. A 9-year-old girl presented with poor balance and ataxia following an episode of upper respiratory tr...
journal_title:Journal of child neurology
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doi:10.1177/0883073808330184
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abstract::We evaluated the neuropsychological and neurologic outcome of 15 long-term survivors of posterior fossa tumors who were treated between 1970 and 1984 with cranial irradiation (n = 15) and surgery (n = 14). The interval between diagnosis and evaluation ranged from 4 to 20 years (median = 10 years). Earlier age at diagn...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389501000308
更新日期:1995-05-01 00:00:00
abstract::Pelizaeus-Merzbacher disease and X-linked spastic paraplegia type 2 are two sides of the same coin. Both arise from mutations in the gene encoding myelin proteolipid protein. The disease spectrum for Pelizaeus-Merzbacher disease and spastic paraplegia type 2 is extraordinarily broad, ranging from a spastic gait in the...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/08830738030180090801
更新日期:2003-09-01 00:00:00
abstract::The clinical picture, family history, laboratory data, treatment modalities, and outcome in 27 juvenile myasthenics seen over a 25-year period are presented. Onset was after 10 years of age in the majority of patients. Half presented with ocular signs, the other half with generalized-onset myasthenia. Half of those wi...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
doi:10.1177/088307389300800422
更新日期:1993-10-01 00:00:00
abstract::The currently available scales for quantitative measurement of the severity of childhood dystonia require human observer ratings and provide poor granularity in the scores for individual limbs. We evaluated the use of new-generation high-quality touchscreens (an iPad) according with the Fitts law, which is a mathemati...
journal_title:Journal of child neurology
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abstract::Sensory rhizotomy in the treatment of spasticity has been evolving over the past century since its first use in 1888. This paper reviews its historical evolution, current physiologic basis, range in current surgical technique, and the outcome, along with complications seen over the past decade since its repopularizati...
journal_title:Journal of child neurology
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更新日期:1996-11-01 00:00:00
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journal_title:Journal of child neurology
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doi:10.1177/0883073812473366
更新日期:2014-03-01 00:00:00
abstract::Germinal matrix hemorrhage refers to bleeding that arises from the subependymal (or periventricular) germinal region of the immature brain. Clinical studies have shown that infants who experience germinal matrix hemorrhage can develop hydrocephalus or suffer from long-term neurologic dysfunction, including cerebral pa...
journal_title:Journal of child neurology
pub_type: 杂志文章,评审
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更新日期:2006-05-01 00:00:00
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journal_title:Journal of child neurology
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更新日期:2008-08-01 00:00:00
abstract::A suppository for rectal administration of carbamazepine has been developed for situations in which it is unsuitable to use the oral route of administration. In an open, controlled, within-patient study, the pharmacokinetics, clinical efficacy, and tolerability of carbamazepine slow-release tablets were compared with ...
journal_title:Journal of child neurology
pub_type: 杂志文章,多中心研究
doi:10.1177/088307389501000209
更新日期:1995-03-01 00:00:00
abstract::Two children are described who suddenly developed an encephalitic illness with intractable bilateral facial seizures. The seizures subsided over several days, but the children were left with the signs of pseudobulbar palsy and are unable to speak or swallow effectively. Bilateral destructive lesions in the opercular r...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307388900400213
更新日期:1989-04-01 00:00:00
abstract:AIM:To investigate the impact of concussion on pupillary function in children by examining pupillometric parameters and assessing for differences in children reporting photosensitivity. METHODS:Retrospective chart review was performed of pediatric patients referred for visual symptoms after concussion from 2017 to 201...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073820964040
更新日期:2021-03-01 00:00:00
abstract::The aim was to explore the relationship of youth age and sex to depressive symptoms and illness attitudes in youth with epilepsy and juvenile rheumatic disease. Youth with epilepsy or juvenile rheumatic disease between the ages of 7 and 19 years completed measures of depressive symptoms and illness attitudes. A signif...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073811431109
更新日期:2012-08-01 00:00:00
abstract::It was recently postulated that because increased genetic load and increased parental age are both purportedly associated with the risk to develop an autism spectrum disorder, there must be a linkage between increasing genetic load and increasing parental age in autism spectrum disorder pathogenesis. The present study...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814541478
更新日期:2014-08-27 00:00:00
abstract::The attention-deficit disorder, with and without hyperactivity, is associated with defective attention, response inhibition and, in attention-deficit disorder with hyperactivity, with motor restlessness. In adults, inattention, defective response inhibition, and impersistence are more commonly seen in right hemisphere...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307389701200207
更新日期:1997-02-01 00:00:00
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journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/088307380101600701
更新日期:2001-07-01 00:00:00
abstract::Metachromatic leukodystrophy is a rare disorder of myelin metabolism. This degenerative disorder results from the accumulation of cerebroside sulfatide within the myelin sheath of central and peripheral nervous system, due to deficiency of aryl sulfatase A enzyme. We report a 5-year-old male child, who presented with ...
journal_title:Journal of child neurology
pub_type: 杂志文章
doi:10.1177/0883073814542948
更新日期:2015-03-01 00:00:00
abstract::Motor speed and accuracy are both affected in childhood dystonia. Thus, deriving a speed-accuracy function is an important metric for assessing motor impairments in dystonia. Previous work in dystonia studied the speed-accuracy trade-off during point-to-point tasks. To achieve a more relevant measurement of functional...
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更新日期:2015-10-01 00:00:00
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journal_title:Journal of child neurology
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abstract::In addition to the typical infantile spasm symptoms, several other symptoms, such as eye movements, have been reported to be associated with infantile spasms, although the relationship between the typical spasms and these other events is not fully understood. Here we present a case with West syndrome. We observed the ...
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pub_type: 杂志文章,评审
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更新日期:1991-01-01 00:00:00
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journal_title:Journal of child neurology
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更新日期:2014-11-01 00:00:00
abstract::Imaging findings of brain damage due to neonatal hypoglycemia are known; however, the effect of childhood hypoglycemia on the brain has not been described well. The authors present the case of a 6-year-old girl who had seizures secondary to hypoglycemia followed up for 1 year as epilepsy. The patient had experienced a...
journal_title:Journal of child neurology
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更新日期:2007-02-01 00:00:00
abstract::The acquisition of reading is a complex neurobiologic process. Identifying the most effective instruction and remedial intervention methods for children at risk of developing reading problems and for those who are already struggling is equally complex. This article aims to provide the clinician with a review of more c...
journal_title:Journal of child neurology
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更新日期:2004-10-01 00:00:00
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journal_title:Journal of child neurology
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更新日期:2012-03-01 00:00:00
abstract::Executive dysfunction occurs in sickle cell anemia, but there are few early data. Infants with sickle cell anemia (n = 14) and controls (n = 14) performed the "A-not-B" and Object Retrieval search tasks, measuring precursors of executive function at 9 and 12 months. Significant group differences were not found. Howeve...
journal_title:Journal of child neurology
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更新日期:2013-10-01 00:00:00
abstract::Elevation and blur of the optic disc margin with hyperemia and flame hemorrhages are classic features of papilledema that may not be present with mild elevations of the cerebral spinal fluid pressure. In children, the disc can be dramatically elevated with indistinct margins in pseudopapilledema. Children with equivoc...
journal_title:Journal of child neurology
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更新日期:2007-07-01 00:00:00
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abstract::Diagnostic ultrasound has been extensively used for neurologic evaluation of cranial, vascular and spinal diseases. This study presents the techniques, methodology, and procedures for a new diagnostic application of ultrasound for evaluation of the neuromuscular system. In order to determine the optimum sonographic ch...
journal_title:Journal of child neurology
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更新日期:1988-01-01 00:00:00