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Prevalence and correlates of DSM-5 eating disorders in patients with bipolar disorder.

Abstract：

OBJECTIVE:To determine prevalence rates and clinical correlates of current DSM-5 eating disorders in patients with bipolar disorder (BP). METHODS:Prevalence rates of current DSM-5- and DSM-IV-defined binge eating disorder (BED), bulimia nervosa (BN), and anorexia nervosa (AN) were assessed with the Eating Disorder Diagnostic Scale (EDDS) in 1092 patients with BP. Psychiatric illness burden was evaluated with five proxy measures of BP illness severity. Medical illness burden was evaluated with the Cumulative Index Rating Scale (CIRS). RESULTS:Twenty-seven percent of patients had a current DSM-5 eating disorder: 12% had BED, 15% had BN, and 0.2% had AN. Rates of DSM-5-defined BED and BN were higher than clinical diagnosis rates and rates of DSM-IV-defined BED and BN. Compared with BP patients without an eating disorder, BP patients with a DSM-5 eating disorder were younger and more likely to be women; had an earlier age of onset of BP; had higher EDDS composite scores and higher degrees of suicidality, mood instability, and anxiety disorder comorbidity; and had a higher mean BMI, higher rate of obesity, and higher CIRS total scores. In a logistic regression model controlling for previously identified correlates of an eating disorder, younger age, female gender, and higher BMI remained significantly associated with an eating disorder. LIMITATIONS:The EDDS has not been validated in BP patients. CONCLUSION:DSM-5-defined BED and BN are common in BP patients, possibly more common than DSM-IV-defined BED and BN, and associated with greater psychiatric and general medical illness burden. Further studies assessing DSM-5 eating disorders in people with BP are greatly needed.

journal_name

J Affect Disord

journal_title

Journal of affective disorders

authors

McElroy SL,Crow S,Blom TJ,Biernacka JM,Winham SJ,Geske J,Cuellar-Barboza AB,Bobo WV,Prieto ML,Veldic M,Mori N,Seymour LR,Bond DJ,Frye MA

doi

10.1016/j.jad.2015.11.010

subject

Has Abstract

pub_date

2016-02-01 00:00:00

pages

216-21

eissn

0165-0327

issn

1573-2517

pii

S0165-0327(15)30519-X

journal_volume

191

pub_type

杂志文章

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