Abstract:
:After 30 years of treatment with Mectizan (ivermectin), cutaneous and ocular complications of Onchocerca volvulus infection are now scarce in endemic communities. Indeed, transmission has been interrupted and the O. volvulus- associated disease has disappeared in some African foci. Despite this success, onchocerciasis elimination in Loa loa co-endemic areas is still constrained by severe adverse events (SAEs) occurring after ivermectin treatment in some individuals harbouring very high L. loa microfilaremia. One approach towards the prevention of these SAEs is to identify individuals with high L. loa microfilaremia and exclude them from ivermectin treatment. The development of the LoaScope has provided the tool that underlies this test and not treat (TaNT) strategy. The first successful TaNT campaign was conducted in a L. loa highly endemic focus in Cameroon in 2015 without any SAEs. To accomplish this within a research setting, 60 people were deployed for this campaign, making this 'research' strategy not sustainable from a cost perspective. We describe here a way of reducing the cost of the TaNT strategy with a smaller team (three people) selected within affected communities. We also suggest the organization of a TaNT campaign in affected countries.
journal_name
Int Healthjournal_title
International healthauthors
Kamgno J,Nana-Djeunga HC,Pion SD,Chesnais CB,Klion AD,Mackenzie CD,Nutman TB,Boussinesq Mdoi
10.1093/inthealth/ihx051subject
Has Abstractpub_date
2018-03-01 00:00:00pages
i49-i53issue
suppl_1eissn
1876-3413issn
1876-3405pii
4868659journal_volume
10pub_type
杂志文章abstract:BACKGROUND:People affected by neglected tropical diseases (NTDs) are frequently the target of social stigmatization. To date not much attention has been given to stigma in relation to NTDs. The objective of this review is to identify the extent of social stigma and the similarities and differences in the causes, manife...
journal_title:International health
pub_type: 杂志文章,评审
doi:10.1093/inthealth/ihv071
更新日期:2016-03-01 00:00:00
abstract:BACKGROUND:A modelling analysis carried out in 2014 suggested that, without cervical cancer screening programmes, the incidence of cervical cancer in Denmark, Finland, Norway and Sweden would have been as high as that in some low- and middle-income countries. We compare programme strategies between Nigeria and these No...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihaa062
更新日期:2020-09-30 00:00:00
abstract:Background:Diarrhoea is a major cause of child mortality. Although oral rehydration solution (ORS) is an efficacious intervention for correcting dehydration, inadequate monitoring may limit its effectiveness in routine settings. We evaluated the effect of using a caregiver-administered chart to monitor oral fluid thera...
journal_title:International health
pub_type: 杂志文章,随机对照试验
doi:10.1093/inthealth/ihy040
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Oxygen is an essential medical therapy that is poorly available globally. We evaluated the quality of oxygen therapy in 12 secondary-level Nigerian hospitals, including access to oxygen equipment, equipment functionality, healthcare worker knowledge and appropriateness of use. METHODS:We conducted a three-p...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihz009
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Several strategies are used in the care of pregnant women accessing antenatal care in primary health centres in Nigeria, with the aim of reducing the burden of malaria and anaemia. The objective of the study was to appraise the prevalence of malaria parasitaemia and anaemia in pregnant women attending antena...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihu009
更新日期:2014-06-01 00:00:00
abstract:BACKGROUND:Among university students, large numbers are involved with smoking and suffer from many chronic diseases. This study examined tobacco smoking prevalence and potential predictors among university students in Sylhet Division, Bangladesh. METHODS:A total of 416 students were selected for face-to-face interview...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihy091
更新日期:2019-07-01 00:00:00
abstract::Every year more than 1.35 million people lose their lives on the road and tens of millions more are injured, some permanently. Since the early 2000s there has been renewed focus on the issue, with the United Nations, World Health Organization and the World Bank placing the issue higher on their agendas. Guided by the ...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihz042
更新日期:2019-09-02 00:00:00
abstract:BACKGROUND:In recent years there have been several reports of outbreaks of dengue fever (DF) in Yemen. This study aimed to describe the prevailing knowledge, attitude and preventive practices regarding DF, and to investigate the factors associated with poor preventive practices in rural areas of Yemen. METHODS:A popul...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihv021
更新日期:2015-11-01 00:00:00
abstract::Preventing and responding to violence against children is an aim of the new Sustainable Development Goals. Numerous agencies are now collecting data from children about violence, including academics, non-governmental organisations, government agencies, consultants and others. Data are necessary to ensure appropriate p...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihw009
更新日期:2016-05-01 00:00:00
abstract::In industrial countries, a number of factors put indigenous peoples at increased risk of HIV infection. National surveillance data between 1999 and 2008 provided diagnoses for Aboriginal and Torres Strait Islanders (Australia), First Nations, Inuit and Métis (Canada excluding Ontario and Quebec) and Māori (New Zealand...
journal_title:International health
pub_type: 杂志文章
doi:10.1016/j.inhe.2011.03.010
更新日期:2011-09-01 00:00:00
abstract::Despite growing interest at national and international levels to use community-directed interventions (CDI) for delivery of health interventions in Africa, inadequate information on its acceptability and effectiveness remains. This study aimed to examine community perceptions on CDI strategy and its effectiveness for ...
journal_title:International health
pub_type: 杂志文章
doi:10.1016/j.inhe.2010.07.009
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Providing compensation for participants in clinical research is well established and while international guidelines exist, defining a context-specific and fair compensation for participants in low-resource settings is challenging due to ethical concerns and the lack of practical, national compensation and re...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihaa066
更新日期:2020-11-09 00:00:00
abstract::The care of severely malnourished children in sub-Saharan Africa is challenging, especially in HIV-prevalent settings. Recent improvements to facility-based individual case management, and increased community-based management focusing on early identification and high programme coverage have led to reductions in mortal...
journal_title:International health
pub_type: 杂志文章
doi:10.1016/j.inhe.2009.03.001
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Individuals in rural communities in Madagascar must frequently travel long distances, over difficult terrain, to obtain basic care. The quality of care is often inconsistent and inadequate. METHODS:An exploratory mixed-methods study was conducted in select coastal communities in the Maroantsetra region of M...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihy070
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Between June 2012 and December 2013 Médecins Sans Frontières launched a pilot project with the aim of testing a strategy for improving timely diagnosis of active pulmonary TB among migrants hosted in four centres of identification and expulsion (CIE) in Italy. METHODS:This is a descriptive study. For active...
journal_title:International health
pub_type: 杂志文章,多中心研究
doi:10.1093/inthealth/ihw025
更新日期:2016-09-01 00:00:00
abstract:Background:Our objective was to demonstrate the feasibility of integrated care for TB, HIV and diabetes mellitus (DM) in a pilot project in Ethiopia. Methods:Healthcare workers in four hospitals screened patients with TB for HIV and DM; patients with HIV for DM and TB; and patients with DM for TB. Fasting and random p...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihx002
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:On 26 December 2004, 280 000 people lost their lives in the Asia-Pacific region. A massive earthquake struck Indonesia, triggering a tsunami that affected several countries, including Thailand. This tsunami had important implications for the health status of Thai citizens and health planning, and thus there ...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/iht004
更新日期:2013-06-01 00:00:00
abstract::Community sensitisation, as a component of community engagement, plays an important role in strengthening the ethics of community-based trials in developing countries and is fundamental to trial success. However, few researchers have shared their community sensitisation strategies and experiences. We report on our per...
journal_title:International health
pub_type: 杂志文章
doi:10.1016/j.inhe.2011.10.003
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Humanitarian emergencies can disproportionately affect women of reproductive age, and children. Good data on reproductive maternal, newborn and child health (RMNCH) are vital to plan and deliver programmes to address RMNCH needs. There is currently a lack of information regarding the availability, use and ap...
journal_title:International health
pub_type: 杂志文章,评审
doi:10.1093/inthealth/ihv045
更新日期:2016-03-01 00:00:00
abstract::Product Development Partnerships (PDPs) are playing an increasingly important role in the development of new medicines for neglected diseases of the developing world; however, there has been limited information on their funding and expenditure patterns. This paper analyses funding for the 14 PDPs working on neglected ...
journal_title:International health
pub_type: 杂志文章
doi:10.1016/j.inhe.2010.04.002
更新日期:2010-06-01 00:00:00
abstract:Background:The State of Meghalaya, India, has some of the worst newborn health outcomes in the country. State health authorities commissioned an assessment of newborn service delivery to improve services. This study proposes bottleneck analysis (BNA) and quality improvement (QI) methods as a combined method to improve ...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihy062
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Employment is a key determinant of health disparity. We examined gender-specific relationships between employment status and health outcomes among Brazilian adults. METHODS:Nationally representative data (n=463 223) came from the 2003 and 2008 Brazilian National Household Surveys. Logistic regressions were ...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihw030
更新日期:2016-11-01 00:00:00
abstract:Background:The objective of this study was to evaluate the comparative effects of three breastfeeding promotion interventions on the duration of exclusive breastfeeding (EBF) and any breastfeeding (BF) among human immunodeficiency virus (HIV)-infected women in Uganda. Methods:Between February 2012 and February 2013, 2...
journal_title:International health
pub_type: 杂志文章,随机对照试验
doi:10.1093/inthealth/ihy041
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:This study presents evidence on the cost of integrated preventive chemotherapy treatment (PCT) to control trachoma, schistosomiasis, lymphatic filariasis and soil-transmitted helminthiasis (STH) in Niger. Integrated PCT costs are compared with the costs of vertical PCT control. METHODS:Data were analysed fo...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihs010
更新日期:2013-03-01 00:00:00
abstract::Hypertension is the most common cause of cardiovascular diseases, accounting for at least half of haemorrhagic and ischaemic strokes, heart failure and renal failure in sub-Saharan Africa. However, population-based data to inform policies are scarce. Using the WHO STEPwise approach to chronic disease risk factor surve...
journal_title:International health
pub_type: 杂志文章
doi:10.1016/j.inhe.2012.09.005
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:Malaria infections are the leading cause of death for children in Madagascar. Insecticide-treated bednets offer effective prevention, but it is unclear how well free bednet distribution programs reach young children. METHODS:We conducted a secondary analysis of a free bednet distribution program in Madagasc...
journal_title:International health
pub_type: 杂志文章,随机对照试验
doi:10.1093/inthealth/iht033
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:School surveys provide a convenient platform to obtain large child cohorts from multiple communities and are widely used as a proxy to determine community prevalence of neglected tropical diseases. The purpose of this study was to compare trachoma prevalence between preschool- and school-aged children and ch...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/iht027
更新日期:2013-12-01 00:00:00
abstract:BACKGROUND:Chronic kidney disease (CKD) is a growing public health problem and an important cause of morbidity and mortality. Disparities in CKD may be related to social determinants and health inequalities in low- and middle-income countries. This study determined how social determinants of health influence trends in ...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihz071
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:A secondary analysis was conducted of two separate datasets to observe the association between maternal age and interpregnancy interval (IPI). METHODS:The IPI in a middle-income country (Guatemala) was compared with that of a very-high-income country (USA) among women with two pregnancies. RESULTS:A regres...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihaa085
更新日期:2020-11-04 00:00:00
abstract:BACKGROUND:Validation of trachoma elimination requires monitoring after discontinuation of trachoma program activities, though such evaluations are not commonly done. METHODS:Conjunctival examinations and smartphone photography were performed on a random sample of pre-school children from 15 villages in a region of Bu...
journal_title:International health
pub_type: 杂志文章
doi:10.1093/inthealth/ihz035
更新日期:2019-11-13 00:00:00