Left Ventricular Assist Devices - A State of the Art Review.

Abstract:

:Cardiovascular diseases are the leading cause of mortality rates throughout the world. Next to an insufficient number of healthy donors, this has led to increasing numbers of patients on heart transplant waiting lists with prolonged waiting times. Innovative technological advancements have led to the production of ventricular assist devices that play an increasingly important role in end stage heart failure therapy. This review is intended to provide an overview of current implantable left ventricular assist devices, different design concepts and implantation techniques. Challenges such as infections and thromboembolic events that may occur during LVAD implantations have also been discussed.

journal_name

Adv Exp Med Biol

authors

Feldmann C,Chatterjee A,Haverich A,Schmitto JD

doi

10.1007/5584_2018_145

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

287-294

eissn

0065-2598

issn

2214-8019

journal_volume

1067

pub_type

杂志文章,评审
  • The ovarian renin-angiotensin system. A paracrine-intracrine regulator of ovarian function.

    abstract::We present a review that considers the regulation of ovarian function by the ovarian renin-angiotensin system. Evidence is presented that shows the ovarian renin-angiotensin system can regulate normal ovarian function by paracrine and intracrine mechanisms. In addition, the complexity that is inherent in the renin-ang...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:

    authors: Pepperell JR,Yamada Y,Nemeth G,Palumbo A,Naftolin F

    更新日期:1995-01-01 00:00:00

  • Pepstatin inhibition mechanism.

    abstract::Pepstatin is a low molecular weight, potent inhibitor specific for acid proteases with a Ki value of about 10(-10)M for pepsin. The chemical structure of pepstatin is essentially a hexapeptide which contains two residues of an unusual amino acid, 4-amino-3-hydroxy-6-methylheptanoic acid (statine). The complete structu...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4757-0719-9_12

    authors: Marciniszyn J Jr,Hartsuck JA,Tang J

    更新日期:1977-01-01 00:00:00

  • Fluctuations of Nutrition-Associated Markers After Decompressive Hemicraniectomy in Middle Cerebral Artery Occlusion Patients.

    abstract::Cerebral infarction (CI) caused by middle cerebral artery occlusion exhibits a very high mortality rate. To reduce this rate, a decompressive hemicraniectomy (DHC) is performed clinically based on several randomized trials. In ischemic stroke, a state of malnutrition leads to poor outcomes. However, little evidence is...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-91287-5_6

    authors: Kutsuna N,Makita K,Goto K,Hirayama K,Kido G,Kagawa Y

    更新日期:2018-01-01 00:00:00

  • Epigenetic Biomarkers of Breast Cancer Risk: Across the Breast Cancer Prevention Continuum.

    abstract::Epigenetic biomarkers, such as DNA methylation, can increase cancer risk through altering gene expression. The Cancer Genome Atlas (TCGA) Network has demonstrated breast cancer-specific DNA methylation signatures. DNA methylation signatures measured at the time of diagnosis may prove important for treatment options an...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-22909-6_2

    authors: Terry MB,McDonald JA,Wu HC,Eng S,Santella RM

    更新日期:2016-01-01 00:00:00

  • How to Tackle Natural Focal Infections: From Risk Assessment to Vaccination Strategies.

    abstract::Natural focal diseases are caused by biological agents associated with specific landscapes. The natural focus of such diseases is defined as any natural ecosystem containing the pathogen's population as an essential component. In such context, the agent circulates independently on human presence, and humans may become...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/5584_2016_199

    authors: Busani L,Platonov AE,Ergonul O,Rezza G

    更新日期:2017-01-01 00:00:00

  • Drebrin in Renal Glomeruli.

    abstract::The central function of renal glomeruli is plasma ultrafiltration for primary urine production. The glomerular filtration barrier consists of a fenestrated endothelium, the glomerular basement membrane and podocytes, mesenchymal-like cells with actin filament-rich protrusions, the "foot processes." Their architecture ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-4-431-56550-5_20

    authors: Ludwig-Peitsch WK

    更新日期:2017-01-01 00:00:00

  • The Bone Microenvironment in Prostate Cancer Metastasis.

    abstract::The propensity of prostate cancer cells to seed the skeleton and then progress into clinically relevant metastatic tumors is widely recognized and a major cause of morbidity and mortality for patients. The natural history of prostate adenocarcinoma most frequently begins with a tumor diagnosed at a localized stage, wh...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-32656-2_9

    authors: DiNatale A,Fatatis A

    更新日期:2019-01-01 00:00:00

  • Serum IgG and IgE antibody against aerosolised antigens from Nephrops norvegicus among seafood process workers.

    abstract::Employees in a seafood factory developed high titers of serum IgE and IgG antibody to antigens from prawn (N. norvegicus) which were aerosolized during processing. Significant serum IgE antibody titers occurred only among those subjects with occupation-related respiratory symptoms, and this serological parameter may b...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-5344-7_101

    authors: McSharry C,Wilkinson PC

    更新日期:1987-01-01 00:00:00

  • Current trend on syphilis diagnosis: issues and challenges.

    abstract::Syphilis is a century old sexually transmitted infection transmitted worldwide. WHO reports 12 million new cases that were identified in 1999, with over 90% of these infections reported from patients from low-income countries. This case number of syphilis is on the rise globally in the Men have sex with Men (MSM) popu...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-81-322-1774-9_5

    authors: Morshed MG

    更新日期:2014-01-01 00:00:00

  • 'Glyco-epitope' assignments for the selectins: advances enabled by the neoglycolipid (NGL) technology in conjunction with synthetic carbohydrate chemistry.

    abstract::The neoglycolipid (NGL) technology involving the preparation of lipid-linked oligosaccharide probes for binding experiments with carbohydrate-recognizing proteins, and their analysis by mass spectrometry, is a unique and powerful means of discovering oligosaccharide ligands for carbohydrate-binding proteins, and assig...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4615-1267-7_5

    authors: Feizi T

    更新日期:2001-01-01 00:00:00

  • Proliferating cells in demyelinating states.

    abstract::Proliferation of mononuclear cells was examined with an autoradiography method in the CSF and peripheral blood of 13 patients with multiple sclerosis (MS), serially during activation of disease in one patient with subacute sclerosis panencephalitis (SSPE), and in some control patients with various neurological conditi...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-2514-7_41

    authors: Reunanen MI,Ilonen J,Järvenpää K

    更新日期:1978-01-01 00:00:00

  • Synthesis, formation, and occurrence of contaminants in biotechnologically manufactured L-tryptophan.

    abstract::The pattern of contaminants in pharmaceutical and feed grade L-tryptophan (Trp) was investigated in a market survey of 22 lots of 6 different manufacturers. To date, 5 case associated contaminants in Showa Denko tryptophan (SD-Trp) known to cause the autoimmune disease eosinophilia-myalgia syndrome (EMS) have been str...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4615-4709-9_59

    authors: Simat TJ,Kleeberg KK,Müller B,Sierts A

    更新日期:1999-01-01 00:00:00

  • Regenerative Medicine: Advances from Developmental to Degenerative Diseases.

    abstract::Chronic tissue and organ failure caused by an injury, disease, ageing or congenital defects represents some of the most complex therapeutic challenges and poses a significant financial healthcare burden. Regenerative medicine strategies aim to fulfil the unmet clinical need by restoring the normal tissue function eith...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-60733-7_12

    authors: Blair NF,Frith TJR,Barbaric I

    更新日期:2017-01-01 00:00:00

  • Progenitors in the Ependyma of the Spinal Cord: A Potential Resource for Self-Repair After Injury.

    abstract::Traumatic injury of the spinal cord leads to devastating conditions that affect ~2.5 million people worldwide. This is because the mammalian spinal cord reacts to injury with only limited endogenous repair. Functional restoration requires the replacement of lost cells, the growth and navigation of regenerating axons o...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-62817-2_13

    authors: Marichal N,Reali C,Rehermann MI,Trujillo-Cenóz O,Russo RE

    更新日期:2017-01-01 00:00:00

  • HER2-Targeted Therapy in Osteosarcoma.

    abstract::In this chapter, we will review studies of HER2 in osteosarcoma and discuss the controversies that have existed in this field. Our present understanding of HER2 in the context of osteosarcoma is that it is expressed on a subset of patient samples, but that expression is not prognostic. We will review the two trials th...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-030-43032-0_5

    authors: Gill J,Hingorani P,Roth M,Gorlick R

    更新日期:2020-01-01 00:00:00

  • An integrated view of the determinants of maximum oxygen uptake.

    abstract::This paper develops an analysis of the interaction between circulatory convective and tissue diffusive O2 transport that explains how VO2 max is set by the integrated response to each and every step in the O2 transport chain from atmosphere to mitochondria. We suggest that it is not useful to search for "the" rate lim...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-5481-9_22

    authors: Wagner PD

    更新日期:1988-01-01 00:00:00

  • Management of recurrent venous thromboembolism.

    abstract::We have described our current criteria for selecting those patients with acute V T-E who merit long-term protection, for accomplishing the acute to long-term transition efficiently and for deciding when such protection can be interrupted. Naturally, in individual patients, special circumstances may exist which alter t...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-1-4757-5985-3_17

    authors: Moser KM

    更新日期:1987-01-01 00:00:00

  • Retinal oxygen tension in diabetic dogs following insulin infusion.

    abstract::We measured preretinal oxygen tensions using a microelectrode in dogs made diabetic with alloxan. The intravenous administration of insulin did not affect preretinal oxygen tension over the two hours it could be continuously accurately measured. Furthermore, the oxygen-hemoglobin equilibrium curves measured before and...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-1188-1_60

    authors: Goldstick TK,Ernest JT,Engerman RL

    更新日期:1984-01-01 00:00:00

  • The Consequences of Hypomorphic RPE65 for Rod and Cone Photoreceptors.

    abstract::RPE65 is essential for both rod- and cone-mediated vision. So far, more than 120 disease-associated mutations have been identified in the human RPE65 gene. Differential clinical manifestations suggested that some patients suffer from null mutations while others retain residual RPE65 activity and some useful vision. To...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-319-17121-0_45

    authors: Samardzija M,Barben M,Geiger P,Grimm C

    更新日期:2016-01-01 00:00:00

  • Myotonic Dystrophy: an RNA Toxic Gain of Function Tauopathy?

    abstract::Myotonic dystrophies (DM) are rare inherited neuromuscular disorders linked to microsatellite unstable expansions in non-coding regions of ubiquitously expressed genes. The DMPK and ZNF9/CNBP genes which mutations are responsible for DM1 and DM2 respectively. DM are multisystemic disorders with brain affection and cog...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-981-32-9358-8_17

    authors: Fernandez-Gomez F,Tran H,Dhaenens CM,Caillet-Boudin ML,Schraen-Maschke S,Blum D,Sablonnière B,Buée-Scherrer V,Buee L,Sergeant N

    更新日期:2019-01-01 00:00:00

  • The use of bayesian networks for heart beat classification.

    abstract::This work proposes to use a static Bayesian network as a tool to support medical decision in the on-line detection of Premature Ventricular Contraction beats (PVC) in electrocardiogram (ECG) records, which is a well known cardiac arrhythmia available for study in standard ECG databases. The main motivation to use Baye...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-0-387-79100-5_12

    authors: de Oliveira LS,Andreão RV,Sarcinelli-Filho M

    更新日期:2010-01-01 00:00:00

  • Alternative Mechanisms of mRNA Translation Initiation in Cellular Stress Response and Cancer.

    abstract::Throughout evolution, eukaryotic cells have devised different mechanisms to cope with stressful environments. When eukaryotic cells are exposed to stress stimuli, they activate adaptive pathways that allow them to restore cellular homeostasis. Most types of stress stimuli have been reported to induce a decrease in ove...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-3-030-19966-1_6

    authors: Lacerda R,Menezes J,Candeias MM

    更新日期:2019-01-01 00:00:00

  • Compartmental modeling of human lactation.

    abstract::A difficult task for a novice modeler is beginning a modeling project. The methods described here delineate the modeling process step by step. Aristole is quoted as having said "One learns to play the flute by playing the flute," and the same principle holds somewhat for modeling. An excellent means for understanding ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4899-1959-5_2

    authors: Novotny JA,Caballero B

    更新日期:1998-01-01 00:00:00

  • Investigating Bacterial Protein Synthesis Using Systems Biology Approaches.

    abstract::Protein synthesis is essential for bacterial growth and survival. Its study in Escherichia coli helped uncover features conserved among bacteria as well as universally. The pattern of discovery and the identification of some of the longest-known components of the protein synthesis machinery, including the ribosome its...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-23603-2_2

    authors: Gagarinova A,Emili A

    更新日期:2015-01-01 00:00:00

  • EBV in T-/NK-Cell Tumorigenesis.

    abstract::Epstein-Barr virus (EBV), which is associated with B-cell proliferative disorders, also transforms T- or natural killer (NK)-lineage cells and has been connected with various T- or NK (T/NK)-cell malignancies, such as extranodal NK/T-cell lymphoma-nasal type and aggressive NK-cell leukemia. Chronic active EBV (CAEBV) ...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-981-10-7230-7_21

    authors: Kimura H

    更新日期:2018-01-01 00:00:00

  • The role of glyoxalase system in renal hypoxia.

    abstract::Methylglyoxal (MG), a highly reactive alpha-oxoaldehyde generated by oxidation of carbohydrate and glycolysis, binds to proteins and forms advanced glycation end products (AGE). MG and MG adducts have been implicated in oxidative stress-related diseases, therefore, MG detoxifying system such as the glyoxalase system (...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4419-1241-1_6

    authors: Inagi R,Kumagai T,Fujita T,Nangaku M

    更新日期:2010-01-01 00:00:00

  • Centred radio-frequency hyperthermia in solid tumours.

    abstract::After some notions on the mechanisms of action of radio-waves on solid tumours, the treatise illustrates the results achieved in the first 125 cases of malignant tumours treated with this method, its results are definitely encouraging, even in cases apparently with no hope. It also describes briefly the histologic mod...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-1-4684-5766-7_41

    authors: Bazzocchi G,Spadoni F,Zambelli M,Camporesi A,Bazzocchi S,Saragoni A

    更新日期:1990-01-01 00:00:00

  • Primary Extragastrointestinal Stromal Tumours in the Hepatobiliary Tree and Telocytes.

    abstract::The first decade of the twenty-first century witnessed the presence and light microscopic, immunophenotypic, and ultrastructural characterization of interstitial Cajal-like cells (coined as 'telocytes') in virtually every extragastrointestinal site of the human body by Laurentiu M. Popescu and his co-workers. Not surp...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章

    doi:10.1007/978-981-10-1061-3_14

    authors: Padhi S,Nayak HK

    更新日期:2016-01-01 00:00:00

  • Engineered Animal Models Designed for Investigating Ethanol Metabolism, Toxicity and Cancer.

    abstract::Excessive consumption of alcohol is a leading cause of lifestyle-induced morbidity and mortality worldwide. Although long-term alcohol abuse has been shown to be detrimental to the liver, brain and many other organs, our understanding of the exact molecular mechanisms by which this occurs is still limited. In tissues,...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-3-319-98788-0_14

    authors: Marshall S,Chen Y,Singh S,Berrios-Carcamo P,Heit C,Apostolopoulos N,Golla JP,Thompson DC,Vasiliou V

    更新日期:2018-01-01 00:00:00

  • Store-operated Ca(2+) entry.

    abstract::Store-operated Ca(2+) entry (SOCE) is an ubiquitous and major mechanism for Ca(2+) influx in mammalian cells with important physiological relevance. Since the discovery of SOCE in 1986 both, the mechanism that communicates the amount of Ca(2+) accumulated in the intracellular Ca(2+) stores to the plasma membrane chann...

    journal_title:Advances in experimental medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1007/978-94-007-2888-2_15

    authors: Berna-Erro A,Redondo PC,Rosado JA

    更新日期:2012-01-01 00:00:00