Abstract:
:A skeleton excavated from the Blossom Mound (CA-SJO-68), a Late Holocene (4350-2980 BP) site located in the northern San Joaquin Valley of California, exhibits evidence of unusual craniofacial and postcranial features consistent with endocrine disease. Burial 37, an adult male approximately 30-40 years of age, shows pronounced development of the mental eminence, glabellar region, and supraorbital arches, as well as elongation of the mandibular ramus, crowding and malocclusion of the anterior dentition, and periosteal bone formation at several enthesis sites. In addition, abnormal enlargement of the sella turcica as well as pneumatization of the frontal and maxillary sinus and mastoid air cells was observed. These skeletal characteristics are consistent with a diagnosis of acromegaly, an endocrine disorder characterized by the enlargement of bone and soft tissue resulting from a pituitary gland tumor that increases the secretion of growth hormone. Onset typically occurs after epiphyseal fusion, a characteristic that distinguishes it from gigantism. This case study utilizes current clinical criteria for diagnosing acromegaly in human skeletal remains and discusses other evidence of this rare condition in the archeological record.
journal_name
Int J Paleopatholjournal_title
International journal of paleopathologyauthors
Bartelink EJ,Willits NA,Chelotti KLdoi
10.1016/j.ijpp.2013.11.003subject
Has Abstractpub_date
2014-03-01 00:00:00pages
37-46eissn
1879-9817issn
1879-9825pii
S1879-9817(13)00133-2journal_volume
4pub_type
杂志文章abstract::Alcohol Related Birth Defects (ARBD) are yet undocumented among past communities, although alcohol is the leading cause of non-heritable birth defects in the US today. We evaluate potential ARBD at Newton Plantation, Barbados (ca. 1660-1820), where earlier studies suggest frequent, community-wide consumption of lead-t...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2013.08.005
更新日期:2013-12-01 00:00:00
abstract::Analytically sophisticated paleoepidemiology is a relatively new development in the characterization of past life experiences. It is based on sound paleopathological observations, accurate age-at-death estimates, an explicit engagement with the nature of mortality samples, and analytical procedures that owe much to ep...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2017.03.007
更新日期:2017-06-01 00:00:00
abstract::This article serves as an introduction to the International Journal of Paleopathology's special issue, Paleo-oncology: Taking Stock and Moving Forward. Reflecting the goals of the special issue, this paper has been designed to provide an overview of the current state of paleo-oncology, to introduce new and innovative ...
journal_title:International journal of paleopathology
pub_type: 历史文章
doi:10.1016/j.ijpp.2018.02.001
更新日期:2018-06-01 00:00:00
abstract::Osteochondritis Dissecans (OD) is a pathological condition of the subchondral bone and surrounding cartilage of synovial joints, associated with strenuous activity and/or trauma. Reports of OD in archaeological skeletal remains are few and the majority demonstrate low OD prevalence (<1%). A predominantly 19th century ...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2017.09.005
更新日期:2017-12-01 00:00:00
abstract::During the 2011 excavation of the site of St. Michael's Litten, in Chichester, England, a female skeleton, dating to the post-Medieval period (1550-1850), with a large, unidentified pelvic mass was uncovered. The mass measured 16.4H×19.0W×24.3L and was 66cm in its greatest circumference; it weighed 3.32kg. The skeleto...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2015.05.003
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:This paper reviews paleo- and archaeoparasitology publications to date, from Iran. The primary focus is the importance of differential diagnosis and the crucial role of interdisciplinary collaborations among parasitologists and other specialists. METHODS:All relevant articles and theses published in Iran thr...
journal_title:International journal of paleopathology
pub_type: 杂志文章,评审
doi:10.1016/j.ijpp.2020.11.005
更新日期:2020-12-19 00:00:00
abstract::We report the case of a probable meningioma in a cranium excavated from the Medieval site of Portmahomack on the Tarbat Peninsula in Scotland (Carver, 2008). Stratigraphic evidence enabled dating of the remains to a post-Pictish and pre-Reformation date. Meningiomas usually arise from the arachnoid membrane of the men...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2016.01.004
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVE:This study examines the evidence of three skeletal markers of childhood health that leave permanent observable changes in the adult skeleton during two climate events, the Medieval Warm Period (MWP) and the Little Ice Age (LIA) that occurred in the medieval period (1050-1536 CE). MATERIAL:A total of 241 adul...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.ijpp.2019.09.003
更新日期:2019-12-01 00:00:00
abstract::This is the first systematic large-scale palaeopathological study of adult vitamin D deficiency osteomalacia. One thousand one hundred and eighty-one skeletons from multiple urban contexts in post-mediaeval England (c. AD 1700-1855) were analysed. Twelve adults with evidence of osteomalacia were identified. When added...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2014.06.004
更新日期:2014-12-01 00:00:00
abstract::This paper discusses the differential diagnosis of an unusual calcified mass found in the pelvic cavity of 45+-year-old female excavated from 15th-18th century Lisbon (Portugal). The mass is relatively large, irregularly shaped, and exhibits a concave base with malformed teeth embedded within its inner surface. Consid...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2017.05.001
更新日期:2017-09-01 00:00:00
abstract:OBJECTIVE:This case study describes a perimortem hip fracture in a documented individual from the Robert J. Terry Skeletal Collection. The purpose of this paper is to comprehend how co-occurring conditions contributed to fracture risk and to understand the effect of the injury on this individual. MATERIALS AND METHODS...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2020.03.004
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:This study explores the differences in frequency and type of trauma found in two Medieval cemeteries in Denmark, as well as the cultural and community implications of those differences. MATERIALS:We examined 235 skeletons from the cemetery at Tjærby (rural) and 170 skeletons from the cemetery at Randers (urb...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2018.10.002
更新日期:2019-03-01 00:00:00
abstract::The objective of the present study is to test our general knowledge of sex-specific survival differences in past northern France societies by implementing the tooth cementum annulations method of age estimation (i.e., cementochronology) to bio-archaeological series. 1255 individual estimated ages at death covering a m...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2015.05.001
更新日期:2016-12-01 00:00:00
abstract::Here we evaluate Bhattacharya et al.'s (2018) recent paper "Whole-genome sequencing of Atacama skeleton shows novel mutations linked with dysplasia" published in Genome Research. In this short report, we examine the hypothesis that the so-called "Atacama skeleton" has skeletal abnormalities indicative of dysplasia, cr...
journal_title:International journal of paleopathology
pub_type: 评论,杂志文章
doi:10.1016/j.ijpp.2018.06.007
更新日期:2018-09-01 00:00:00
abstract::A description of the late mediaeval skeleton (AD 1150-1539) of a young child with probable signs of tuberculosis is presented. This individual was recovered along with one hundred and ninety skeletons from the cemetery of the priory of SS Peter and Paul, Taunton, Somerset. Aged between three and five years old at deat...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2012.04.001
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:Skeletons sampled for ancient human DNA analysis are sometimes complete enough to provide information about the lives of the people they represent. We focus on three Later Stone Age skeletons, ca. 2000 B.P., from coastal KwaZulu-Natal, South Africa, whose ancient genomes have been sequenced (Schlebusch et al., ...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2018.10.008
更新日期:2019-03-01 00:00:00
abstract::The paper presents a post-mortem examination performed on an adult male from the town of Radom in central Poland. The calotte of this individual had been surgically opened after death with a saw. Based on the archaeological context, this was most probably a Radom resident. The stratigraphy, archaeological artefacts an...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2013.06.002
更新日期:2013-12-01 00:00:00
abstract::The Neolithic colonisation of the Pacific islands was one of the most challenging migration events in human history. The regions east of the Solomon Islands were colonised relatively recently by a people known as the Lapita. The Lapita brought with them a 'transported landscape' of domesticated plants and animals that...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2014.03.001
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVE AND MATERIALS:This research evaluates the presence and chronology of tuberculosis (TB) in the northeastern highlands of Peru (CE 800-1535) through the analysis of osseous lesions from Pre-Contact Kuelap, Chachapoyas. METHODS:We examined macroscopic lesion morphology and distribution from the skeletal series ...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2020.04.002
更新日期:2020-09-01 00:00:00
abstract::Only relatively few cases of dental abnormalities in wild ruminants have thus far been described in the paleopathological literature. This study reports a case of cementoblastoma, a benign odontogenic tumor of ectomesenchymal origin, in a red deer (Cervus elaphus) from the Late Pleistocene of Rochedane, a prehistoric ...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2014.09.004
更新日期:2015-03-01 00:00:00
abstract::This report describes two adjacent, longitudinally-fused anterior cervical vertebrae from a basal archosauromorph. The specimen was collected from the Denwa Formation, Satpura Gondwana Basin, India. The differential diagnosis of the fusion includes genetic or environmentally-mediated congenital malformations, nonspeci...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2017.10.010
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVE:To evaluate lesions on a cranium from the Iberian Peninsula and assess its medico-historical and paleopathological significance. MATERIALS:The skeletal remains of a juvenile individual found in a Medieval Islamic grave (10th -16th century) in Eastern Spain. METHODS:Macroscopic examination of the left and ri...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2020.10.009
更新日期:2020-11-21 00:00:00
abstract:OBJECTIVE:Irregular incremental lines (ILs) in the tooth cementum were previously associated with pregnancy and certain diseases. This study aims to identify irregular ILs and assess their patterns and reproducibility. MATERIALS:24 recent and 32 archaeological teeth from the nineteenth century with known birth history...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2019.07.003
更新日期:2019-12-01 00:00:00
abstract::Dental root fractures are rarely documented in past human populations, but when they are observed, diagnosing ante-mortem events as causal factors can be difficult due to postmortem alteration. Can high resolution X-ray computed tomography (CT) improve our ability to diagnose if a dental fracture was caused ante- or p...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2017.10.004
更新日期:2018-09-01 00:00:00
abstract::Irtieru is a male mummy enclosed in cartonnage, dating to the Third Intermediate Period in the Egyptian collection of the Museu Nacional de Arqueologia in Lisbon. The computed tomography scans of this mummy showed a small dense bean-shaped structure at the left lumbar region. Its anatomical location, morphologic and s...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2015.07.002
更新日期:2015-12-01 00:00:00
abstract::A case of potentially dedifferentiated parosteal osteosarcoma was found in the proximal humerus of an adult female buried in the late Anglo-Saxon cemetery of Cherry Hinton, Cambridgeshire, UK. Key features include a large, dense, lobulated mass attached to the medial metaphysis of the proximal humerus by a broad-based...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2016.12.001
更新日期:2018-06-01 00:00:00
abstract::Investigating injury recidivism and individuals with multiple injuries is an area of growing interest in bioarchaeology. Differentiating between whether an individual sustained multiple injuries, represented by antemortem healed fractures, in one incident or in multiple incidents over the life course, is a major chall...
journal_title:International journal of paleopathology
pub_type: 历史文章,杂志文章
doi:10.1016/j.ijpp.2018.08.003
更新日期:2019-03-01 00:00:00
abstract::Saranda Kolones (Forty Columns) at Paphos in Cyprus was a mediaeval concentric castle built after King Richard I of England captured the island in 1191AD, during the Third Crusade. The aim of this research is to determine whether the garrison of the castle was infected by intestinal parasitic helminths (endoparasites)...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2013.04.003
更新日期:2013-09-01 00:00:00
abstract::Survival of an adult male (M9) with juvenile-onset quadriplegia in Neolithic Vietnam indicates provision of continuous care from his community, and adds to the growing literature documenting survival of disabled individuals in prehistory. Although the role of care-giving in achieving survival is occasionally acknowled...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2011.02.003
更新日期:2011-03-01 00:00:00
abstract::Hypertrophic osteopathy (HO) has been reported in numerous mammalian species, but no reports address the range of conditions that can lead to HO, or the implications of those conditions, for archaeological diagnosis. We describe suspected HO from skeletal remains of an ancient large domestic dog recovered in Iowa, USA...
journal_title:International journal of paleopathology
pub_type: 杂志文章
doi:10.1016/j.ijpp.2015.02.001
更新日期:2015-06-01 00:00:00