Papillomaviruses in ruminants: An update.

Abstract:

:Papillomaviruses (PVs) are complex viruses which infect the skin or mucosae of a broad range of amniotes worldwide. They cause benign or malignant lesions depending on environmental factors, virus oncogenicity and the location of infection. Bovine papillomaviruses (BPVs) are the second most studied PVs beyond human PVs. In the past few years, genetic characterization of animal PVs has increased due to the availability of new techniques, which simplified the sequencing of entire genomes. Therefore, this review aims to provide an update of the current epidemiology, classification and genome features of ruminant PVs (mainly BPVs) affecting animals worldwide. The review also aimed to clarify the key differences between the high-risk Delta papillomaviruses and the seemingly low-risk Xi, Epsilon, Dyoxi and Dyokappapillomavirus as well as the recently described PVs BPV18, 19, 21 and PpuPV1 that belongs to an unclassified genus.

journal_name

Transbound Emerg Dis

authors

Daudt C,Da Silva FRC,Lunardi M,Alves CBDT,Weber MN,Cibulski SP,Alfieri AF,Alfieri AA,Canal CW

doi

10.1111/tbed.12868

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

1381-1395

issue

5

eissn

1865-1674

issn

1865-1682

journal_volume

65

pub_type

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