Abstract:
Background and Objectives:EUS guided core biopsy was once rarely performed but is now entering mainstream practice. Neuroendocrine tumors often warrant core biopsy as sufficient tissue must be obtained to allow for special staining to ensure a correct diagnosis. Traditionally these lesions were sampled with FNA needles. We performed a retrospective pilot study to evaluate the clinical value and efficacy of the a new EUS core needle biopsy needle as compared to a standard EUS FNA needle in the evaluation of patients with known or suspected neuroendocrine tumors. Methods:A retrospective analysis of the first 10 patients (between January 2015 and April 2016) to undergo EUS-FNA with the SharkCore® needle at the University of Utah School of Medicine/Huntsman Cancer Center with neuroendocrine tumors. Each case was retrospectively reviewed by a board certified cytopathologist (BLW) for the following cytologic parameters on the aspirate smears or touch/squash preparations: overall cellularity [1 (low) to 3 (high)], percentage of obtained cells that were lesional/representative (<25%, 26%-50%, and >50%), relative ease of interpretation [1 (difficult) to 3 (easy)]. Pathologic material and reporting records were also reviewed for each case to confirm the number of needle passes to achieve diagnostic adequacy, the presence or absence diagnostic material on H&E slide (from cell block, if prepared), whether a definitive diagnosis was able to be rendered, and the presence or absence of a true core/core fragments (within the cell block, if prepared). Results:A total of 20 patients underwent EUS-FNA for suspected neuroendocrine lesions. Ten patients underwent either transgastric or transduodenal EUS-FNA with the 22 gauge SharkCore® needle. The comparison cohort of 10 patients underwent either transgastric or transduodenal EUS-FNA with the standard 22 gauge Echotip® needle. The SharkCore® needle required a fewer mean number of needle passes to obtain diagnostic adequacy than the Echotip® (P=0.0074). For cases with cell blocks, the SharkCore® needle produced diagnostic material in 100% of cases, whereas Echotip® produced diagnostic material in 60% of cases. There was no significant difference between specimen cellularity, percentage of lesional material, or ease of interpretation between the two needle types. Conclusion:Our pilot investigation targeting patients with known or suspected pancreatic NETs indicates that the SharkCore® needle shows promise in obtaining suitable tissue for ancillary testing that can allow for more definitive pathologic interpretations on EUS FNA specimens. Fewer passes were needed with the core needle when compared to a standard needle.
journal_name
Endosc Ultrasoundjournal_title
Endoscopic ultrasoundauthors
Witt BL,Factor RE,Chadwick BE,Caron J,Siddiqui AA,Adler DGdoi
10.4103/eus.eus_51_17subject
Has Abstractpub_date
2018-09-01 00:00:00pages
323-328issue
5eissn
2303-9027issn
2226-7190pii
229174journal_volume
7pub_type
杂志文章abstract::Endobronchial ultrasound (EBUS) has gained importance for mediastinal lymph node staging. Contrast-enhanced EBUS is so far not a discussed technique including contrast-enhanced high mechanical index (MI)-EBUS and potentially contrast-enhanced low MI-EBUS. Possible use could include characterization of mediastinal lymp...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.4103/2303-9027.200215
更新日期:2017-01-01 00:00:00
abstract::Insulinoma is the most common functioning islet cell tumor of the pancreas, with an annual incidence of 4 cases/1 million individuals. It is treated by surgical methods. Open surgery was once considered the standard approach for the treatment of insulinoma. However, the procedure is traumatic and requires a large inci...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.4103/2303-9027.194703
更新日期:2017-05-01 00:00:00
abstract::The European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) introduced guidelines on the use of contrast-enhanced ultrasound (CEUS) in 2004. This EFSUMB-document focused mainly on liver applications. However, new applications extending beyond the liver were developed thereafter. Increased inte...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.7178/eus.03.003
更新日期:2012-10-01 00:00:00
abstract::Lung cancer is one of the major causes of death in the world. Small cell carcinoma is the most aggressive type and can spread rapidly. The association of a small cell carcinoma with hepatic hilar metastasis and biliary obstruction is rare. Endoscopic ultrasound allows the aspiration of a cytology sample from adenopath...
journal_title:Endoscopic ultrasound
pub_type:
doi:10.4103/2303-9027.193570
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Endoscopic ultrasonography (EUS)-guided fine-needle aspiration (FNA) have a better accuracy for the detection of pancreatic tumors compared with others images modalities. We assessed if the image criteria of elastography and contrast harmonic echo-endoscopic ultrasound could help in choosing the appropriat...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Extra-pancreatic cysts (EPCs) are incidentally found in patients with pancreatic cystic lesions (PCLs). The aim of this study is to find the prevalence of concurrent EPC in patients with PCLs, investigate associations with neoplastic lesions, and compare the prevalence of EPC to a control popu...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/2303-9027.163001
更新日期:2015-07-01 00:00:00
abstract::Postoperative pancreatic fluid collection (POPFC) is an important complication following abdominal surgery. POPFC causes significant morbidity and mortality. Management options are time-consuming and severely affect patient's quality of life. Surgical and/or percutaneous drainage (PCD) is the traditional mainstay of t...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.4103/eus.eus_18_19
更新日期:2019-09-01 00:00:00
abstract::Numerous clinical pathways exist for patients presenting with a suspicious pancreatic mass. These range from direct surgical intervention following staging, with preoperative cross-sectional imaging, EUS with or without fine-needle aspiration or fine-needle core biopsy; neoadjuvant chemotherapy and/or radiation therap...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_28_20
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Contrast-enhanced harmonic endoscopic ultrasound (CEH-EUS) is a novel technology that can identify subepithelial tumors (SETs) by detecting the degree of enhancement, but whether CEH-EUS can predict the malignancy risk of gastrointestinal stromal tumors (GISTs) remains unclear. The aim of our ...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/2303-9027.195871
更新日期:2016-11-01 00:00:00
abstract::Endobronchial ultrasound (EBUS) is a useful technique for the diagnosis and staging of the lung and mediastinal lesions, which is crucial for selecting treatment protocol. Under EBUS guidance, transbronchial needle aspiration (TBNA) is widely applied for obtaining specimens for histological, cytological, and molecular...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.4103/eus.eus_40_18
更新日期:2018-11-01 00:00:00
abstract::Pancreatic pseudocysts are fluid collections in the peripancreatic tissues associated with acute or chronic pancreatitis. Endoscopic ultrasound (EUS)-guided drainage has become an established indication, having better results as compared to percutaneous drainage, nonguided endoscopic drainage, or surgical drainage. Th...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/2303-9027.170424
更新日期:2015-10-01 00:00:00
abstract:Background and Objectives:EUS-FNA is applied widely in clinical practice, but there remains a lack of authentic training models. The present study aimed to develop a novel swine training model and to perform a preliminary assessment of its feasibility and efficacy. Materials and Methods:To create an internal lesion-li...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_13_20
更新日期:2020-07-01 00:00:00
abstract:Background and Objective:The widespread use of colonoscopy has led to an increasing number of subepithelial lesions (SELs) being detected in the lower gastrointestinal (GI) tract. This study aimed to analyze the utility of EUS and its role in the management of lower GI SELs. Patients and Methods:Records of all patient...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_51_20
更新日期:2020-09-01 00:00:00
abstract:Background and Objectives:The radial echoendoscope is still widely used for the investigation of abnormalities in the gastrointestinal wall and for stone detection in the extrahepatic biliary tree. Due to aging patient population, EUS is frequently performed in fragile and elderly individuals. We aimed to compare the m...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_3_19
更新日期:2019-09-01 00:00:00
abstract:Background and Objectives:EUS-guided tissue acquisition with rapid on-site cytologic evaluation (ROSE) has been used to increase the diagnostic yield. However, ROSE is not available in many centers. To date, only a few studies have assessed the adequacy of histologic cores in macroscopic on-site evaluation (MOSE) durin...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_34_19
更新日期:2019-09-01 00:00:00
abstract::[This corrects the article DOI: 10.4103/eus.eus_9_19]. ...
journal_title:Endoscopic ultrasound
pub_type: 已发布勘误
doi:10.4103/2303-9027.282542
更新日期:2020-05-01 00:00:00
abstract::For a definitive diagnosis of fine-needle aspiration (FNA)/biopsy, one of the reliable techniques to determine the adequacy and accuracy rapid on-site evaluation (ROSE) of cytological samples is preferable. Because of the lack of trained pathologists, alternatives have to be explored. This study is primarily conducted...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_27_20
更新日期:2020-11-01 00:00:00
abstract::Submucosal tumors (SMTs) are usually discovered fortuitously during routine endoscopy, including various non-neoplastic and neoplastic conditions. Endoscopic ultrasound (EUS) is considered to be the best imaging procedure to characterize SMTs and to determine the need for further treatment. In this review, the followi...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.7178/eus.06.003
更新日期:2013-07-01 00:00:00
abstract:INTRODUCTION:The number of endoscopic ultrasonography (EUS) for esophageal subepithelial lesion (SEL) is on the increase recently. We retrospectively investigated the 230 patients who underwent EUS for esophageal SEL from July 2010 to June 2013. We analyzed EUS finding and assumptive diagnosis. RESULTS:Among 230 enrol...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
abstract::This systematic review aims to assess the literature to determine the impact of EUS for diagnosing malignancy among indeterminate extrahepatic biliary strictures. A systematic review was performed using MEDLINE, EMBASE, Cochrane, and conference proceedings from inception to July 2016. Pooled results were calculated us...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.4103/eus.eus_24_19
更新日期:2019-09-01 00:00:00
abstract::EUS-guided biliary drainage (EUS-BD) has been used as a salvage modality for relief of malignant biliary obstruction (MBO) after a failed ERCP. Multiple recent randomized controlled trials (RCTs) and observational studies have been published to assess the suitability of EUS-BD as a first-line modality for achieving pa...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.4103/eus.eus_10_20
更新日期:2020-09-01 00:00:00
abstract::Pancreatic metastases are rare, ranging from 2% to 5% of pancreatic malignancies. Differentiating a primary pancreatic malignancy from a metastasis can be difficult due to similarities on imaging findings, but is crucial to ensure proper treatment. Although transabdominal ultrasound, computed tomography, and magnetic ...
journal_title:Endoscopic ultrasound
pub_type:
doi:10.4103/2303-9027.156746
更新日期:2015-04-01 00:00:00
abstract::Endoscopic ultrasound (EUS) is a reference technique for diagnosing and staging several different diseases. EUS-guided biopsies and fine needle aspirations are used to improve diagnostic performance of cases where a definitive diagnosis cannot be obtained through conventional EUS. However, EUS-guided tissue sampling r...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章,评审
doi:10.7178/eus.01.003
更新日期:2012-04-01 00:00:00
abstract::Metastatic cancer to the pancreas is rare and accounts for less than 2% of all pancreatic malignancies. Renal cell cancer, malignant melanoma, lung, colon and breast carcinoma are among the few tumors known to metastasize to the pancreas. The pancreas is a rare site of solitary metastasis, but it is often involved in ...
journal_title:Endoscopic ultrasound
pub_type:
doi:10.4103/2303-9027.121248
更新日期:2013-10-01 00:00:00
abstract:INTRODUCTION:Hemosuccus pancreaticus (HP), hemorrhage from the papilla of Vater through the pancreatic duct (PD), is a rare cause of upper gastrointestinal bleeding. It may be caused by chronic pancreatitis, pseudoaneurism and pancreatic tumors. Only 2% of HP involves the hepatic arteries. Endoscopic ultrasound (EUS) m...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
abstract:Background and Objectives:EUS-guided biliary drainage (EUS-BD) is increasingly reported as a salvage technique after failed endoscopic retrograde cholangiopancreatography, but it is still controversial whether EUS-BD can replace transpapillary biliary stenting. Therefore, we conducted this multicenter, prospective stud...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_17_18
更新日期:2019-03-01 00:00:00
abstract::Pancreatic adenocarcinoma may account for more than 80% of all pancreatic neoplasms. Occasionally, other rare tumors such as lymphoma, metastatic tumor, and solid pseudopapillary neoplasm can be considered in the differential diagnosis. We report the case of an 82-year-old man with a pancreatic solid mass. This case s...
journal_title:Endoscopic ultrasound
pub_type:
doi:10.4103/2303-9027.190923
更新日期:2017-07-01 00:00:00
abstract::There is a paucity of literature on the use of endoscopic ultrasound (EUS) for evaluating superior mediastinal structures, especially the thymus gland. We report a case of thymic carcinoma diagnosed by using EUS elastography with strain ratio and fine-needle aspiration (FNA). A 64-year-old woman presented with altered...
journal_title:Endoscopic ultrasound
pub_type:
doi:10.4103/2303-9027.183975
更新日期:2016-05-01 00:00:00
abstract:Objectives:The project is aimed to compare the tissue sampling rate and the diagnostic accuracy rate of EUS-FNA using 22G nitinol and reverse bevel-tipped needles. Subjects and Methods:This was a prospective, randomized, crossover study in a tertiary academic hospital. All consecutive adult patients undergoing EUS-gui...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_113_17
更新日期:2018-01-01 00:00:00
abstract:Background and Objectives:We investigated the relationship between the interruption of the muscularis propria of the lower esophageal sphincter (LES) measured by EUS and the relief of dysphagia in patients with esophageal achalasia treated by per-oral endoscopic myotomy (POEM). Patients and Methods:Patients with achal...
journal_title:Endoscopic ultrasound
pub_type: 杂志文章
doi:10.4103/eus.eus_30_20
更新日期:2020-07-01 00:00:00