Ancestral Function and Diversification of a Horizontally Acquired Oomycete Carboxylic Acid Transporter.

abstract：:ModelTest-NG is a reimplementation from scratch of jModelTest and ProtTest, two popular tools for selecting the best-fit nucleotide and amino acid substitution models, respectively. ModelTest-NG is one to two orders of magnitude faster than jModelTest and ProtTest but equally accurate and introduces several new featur...

journal_title：Molecular biology and evolution

authors： Darriba D,Posada D,Kozlov AM,Stamatakis A,Morel B,Flouri T

更新日期：2020-01-01 00:00:00

abstract：:Chaperone-mediated autophagy (CMA) is a major pathway of lysosomal proteolysis recognized as a key player of the control of numerous cellular functions, and whose defects have been associated with several human pathologies. To date, this cellular function is presumed to be restricted to mammals and birds, due to the a...

journal_title：Molecular biology and evolution

authors： Lescat L,Véron V,Mourot B,Péron S,Chenais N,Dias K,Riera-Heredia N,Beaumatin F,Pinel K,Priault M,Panserat S,Salin B,Guiguen Y,Bobe J,Herpin A,Seiliez I

更新日期：2020-10-01 00:00:00

abstract：:Single-copy nuclear DNAs (scnDNAs) of eight species of arvicoline and six species of murine rodents were compared using DNA-DNA hybridization. The branching pattern derived from the DNA comparisons is congruent with the fossil evidence and supported by comparative biochemical, chromosomal, and morphological studies. T...

journal_title：Molecular biology and evolution

authors： Catzeflis FM,Sheldon FH,Ahlquist JE,Sibley CG

更新日期：1987-05-01 00:00:00

abstract：:Pax genes play key regulatory roles in embryonic and sensory organ development in metazoans but their evolution and ancestral functions remain widely unresolved. We have isolated a Pax gene from Placozoa, beside Porifera the only metazoan phylum that completely lacks nerve and sensory cells or organs. These simplest k...

journal_title：Molecular biology and evolution

authors： Hadrys T,DeSalle R,Sagasser S,Fischer N,Schierwater B

更新日期：2005-07-01 00:00:00

abstract：:The spread of farming out of the Balkans and into the rest of Europe followed two distinct routes: An initial expansion represented by the Impressa and Cardial traditions, which followed the Northern Mediterranean coastline; and another expansion represented by the LBK (Linearbandkeramik) tradition, which followed the...

journal_title：Molecular biology and evolution

authors： Olalde I,Schroeder H,Sandoval-Velasco M,Vinner L,Lobón I,Ramirez O,Civit S,García Borja P,Salazar-García DC,Talamo S,María Fullola J,Xavier Oms F,Pedro M,Martínez P,Sanz M,Daura J,Zilhão J,Marquès-Bonet T,Gilbert MT,

更新日期：2015-12-01 00:00:00

abstract：:To test whether gaps resulting from sequence alignment contain phylogenetic signal concordant with those of base substitutions, we analyzed the occurrence of indel mutations upon a well-resolved, substitution-based tree for three nuclear genes in bumble bees (Bombus, Apidae: Bombini). The regions analyzed were exon an...

journal_title：Molecular biology and evolution

authors： Kawakita A,Sota T,Ascher JS,Ito M,Tanaka H,Kato M

更新日期：2003-01-01 00:00:00

abstract：:Despite the importance of plant-plant interactions on plant community dynamics and crop yield, our understanding of the adaptive genetics underlying these interactions is still limited and deserves to be investigated in the context of complex and diffuse interactions occurring in plant assemblages. Here, based on 145 ...

journal_title：Molecular biology and evolution

authors： Frachon L,Mayjonade B,Bartoli C,Hautekèete NC,Roux F

更新日期：2019-07-01 00:00:00

abstract：:Baleen whales (suborder Mysticeti) comprise 11 extant species that are classified into four families. Although several phylogenetic hypotheses about these taxa have been proposed, their phylogenetic relationships remain confused. We addressed this problem using short interspersed repetitive element (SINE) insertion da...

journal_title：Molecular biology and evolution

authors： Nikaido M,Hamilton H,Makino H,Sasaki T,Takahashi K,Goto M,Kanda N,Pastene LA,Okada N,SMBE Tri-National Young Investigators.

更新日期：2006-05-01 00:00:00

abstract：:Hybridization in plants may result in hybrid speciation or introgression and, thus, is now widely understood to be an important mechanism of species diversity on an evolutionary timescale. Hybridization is particularly common in ferns, as is polyploidy, which often results from hybrid crosses. Nevertheless, hybrid spe...

journal_title：Molecular biology and evolution

authors： Wang J,Dong S,Yang L,Harris A,Schneider H,Kang M

更新日期：2020-09-01 00:00:00

abstract：:We have used analysis of variance to partition the variation in synonymous and amino acid substitution rates between three effects (gene, lineage, and a gene-by-lineage interaction) in mammalian nuclear and mitochondrial genes. We find that gene effects are stronger for amino acid substitution rates than for synonymou...

journal_title：Molecular biology and evolution

authors： Smith NG,Eyre-Walker A

更新日期：2003-01-01 00:00:00

abstract：:Whole-genome duplications (WGDs) have contributed to gene-repertoire enrichment in many eukaryotic lineages. However, most duplicated genes are eventually lost and it is still unclear why some duplicated genes are evolutionary successful whereas others quickly turn to pseudogenes. Here, we show that dosage constraints...

journal_title：Molecular biology and evolution

authors： Gout JF,Lynch M

更新日期：2015-08-01 00:00:00

abstract：:Chemosensory genes are frequently the target of positive selection and are often present in large gene families, but little is known about heterogeneity of selection in these cases and its relation to function. Here, we use the vomeronasal-1 receptor (V1R) repertoire of mouse lemurs (Microcebus spp.) as a model system...

journal_title：Molecular biology and evolution

authors： Hohenbrink P,Radespiel U,Mundy NI

更新日期：2012-12-01 00:00:00

abstract：:In all anthropoid species, the coding region of the involucrin gene contains a segment of short tandem repeats that were added sequentially, beginning in a common anthropoid ancestor. The involucrin coding region of each of two platyrrhine species, the white-fronted capuchin (Cebus albifrons) and the cottontop tamarin...

journal_title：Molecular biology and evolution

authors： Phillips M,Rice RH,Djian P,Green H

更新日期：1991-09-01 00:00:00

abstract：:The major histocompatibility complex (MHC) class II molecule consists of noncovalently associated alpha and beta chains. In mammals studied so far, the class II MHC can be divided into a number of regions, each containing one or more alpha-chain genes (A genes) and beta-chain genes (B genes), and it has been known for...

journal_title：Molecular biology and evolution

authors： Hughes AL,Nei M

更新日期：1990-11-01 00:00:00

abstract：:Homologues of glucosephosphate isomerase (GPI, EC 5.3.1.9) were purified to homogeneity and kinetically characterized from Mytilus edulis and Isognomon alatus, two bivalve molluscs experiencing contrasting thermal environments. The enzyme isolated from I. alatus functions at warmer temperatures (25-35 C) than GPI from...

journal_title：Molecular biology and evolution

authors： Hall JG

更新日期：1985-05-01 00:00:00

abstract：:TATA box, the core promoter element, exists in a broad range of eukaryotes, and the expression of TATA-containing genes usually responds to various environmental stresses. Hence, the evolution of TATA-box in duplicate genes may provide some clues for the interrelationship among environmental stress, expression differe...

journal_title：Molecular biology and evolution

authors： Zou Y,Huang W,Gu Z,Gu X

更新日期：2011-10-01 00:00:00

abstract：:A phylogenetic tree of a gene family of nicotinic acetylcholine receptor subunits was constructed using 84 nucleotide sequences of receptor subunits from 18 different species in order to elucidate the evolutionary origin of receptor subunits. The tree constructed showed that the common ancestor of all subunits may hav...

journal_title：Molecular biology and evolution

authors： Tsunoyama K,Gojobori T

更新日期：1998-05-01 00:00:00

abstract：:The proportion of functional sequence in the human genome is currently a subject of debate. The most widely accepted figure is that approximately 5% is under purifying selection. In Drosophila, estimates are an order of magnitude higher, though this corresponds to a similar quantity of sequence. These estimates depend...

journal_title：Molecular biology and evolution

authors： Oldmeadow C,Mengersen K,Mattick JS,Keith JM

更新日期：2010-04-01 00:00:00

abstract：:Non-long terminal repeat retroelements continue to impact the human genome through cis-activity of long interspersed element-1 (LINE-1 or L1) and trans-mobilization of Alu. Current activity is dominated by modern subfamilies of these elements, leaving behind an evolutionary graveyard of extinct Alu and L1 subfamilies....

journal_title：Molecular biology and evolution

authors： Wagstaff BJ,Kroutter EN,Derbes RS,Belancio VP,Roy-Engel AM

更新日期：2013-01-01 00:00:00

abstract：:Effective population size is fundamental in population genetics and characterizes genetic diversity. To infer past population dynamics from molecular sequence data, coalescent-based models have been developed for Bayesian nonparametric estimation of effective population size over time. Among the most successful is a G...

journal_title：Molecular biology and evolution

authors： Gill MS,Lemey P,Faria NR,Rambaut A,Shapiro B,Suchard MA

更新日期：2013-03-01 00:00:00

abstract：:Sherpa population is an ethnic group living in south mountainside of Himalayas for hundreds of years. They are famous as extraordinary mountaineers and guides, considered as a good example for successful adaptation to low oxygen environment in Tibetan highlands. Mitochondrial DNA (mtDNA) variations might be important ...

journal_title：Molecular biology and evolution

authors： Kang L,Zheng HX,Chen F,Yan S,Liu K,Qin Z,Liu L,Zhao Z,Li L,Wang X,He Y,Jin L

更新日期：2013-12-01 00:00:00

abstract：:Analysis of mitochondrial DNA restriction fragment length polymorphism in European anchovy (Engraulis encrasicolus) revealed a large number of mitotypes that form two distinct clusters (phylads). Phylad A consists of one common mitotype and many rare secondary mitotypes that are one mutational step removed from the ma...

journal_title：Molecular biology and evolution

authors： Magoulas A,Tsimenides N,Zouros E

更新日期：1996-01-01 00:00:00

abstract：:Positive selection sites (PSSs), a class of amino acid sites with an excess of nonsynonymous to synonymous substitutions, are indicators of adaptive molecular evolution and have been detected in many protein families involved in a diversity of biological processes by statistical approaches. However, few studies are co...

journal_title：Molecular biology and evolution

authors： Zhu L,Peigneur S,Gao B,Zhang S,Tytgat J,Zhu S

更新日期：2016-08-01 00:00:00

abstract：:The human major histocompatibility complex (Mhc) is a chromosomal segment approximately 4 million bp long that contains > or = 84 genes. Some of these genes code for the class I and class II molecules, while the remaining genes code for complement components, cytochrome P450, tumor necrosis factor, and many other, unr...

journal_title：Molecular biology and evolution

authors： Klein J,O'hUigin C,Figueroa F,Mayer WE,Klein D

更新日期：1993-01-01 00:00:00

abstract：:Single-stranded DNA(ssDNA) viral life cycles must balance double-stranded DNA (dsDNA) and ssDNA biosynthesis. Previously published in vitro results suggest that microvirus C and host cell SSB proteins play antagonistic roles to achieve this balance. To investigate this in vivo, microvirus DNA replication was character...

journal_title：Molecular biology and evolution

authors： Doore SM,Baird CD,2012 University of Arizona Virology Undergraduate Lab.,Roznowski AP,Fane BA

更新日期：2014-06-01 00:00:00

abstract：:The selective constraints influencing mRNA editing in plant organelles are largely unknown. To investigate these, we compared patterns of editing between monocot and dicot mitochondrial mRNA. On average, 24% of sites that are edited form C to U in one species have been substituted during evolution by a genomic T in th...

journal_title：Molecular biology and evolution

authors： Shields DC,Wolfe KH

更新日期：1997-03-01 00:00:00

abstract：:Database searches of the Caenorhabditis elegans and human genomic DNA sequences revealed genes encoding ribonuclease H1 (RNase H1) and RNase H2 in each genome. The human genome contains a single copy of each gene, whereas C. elegans has four genes encoding RNase H1-related proteins and one gene for RNase H2. By analyz...

journal_title：Molecular biology and evolution

authors： Arudchandran A,Cerritelli SM,Bowen NJ,Chen X,Krause MW,Crouch RJ

更新日期：2002-11-01 00:00:00

abstract：:DNA supercoiling is the master function that interconnects chromosome structure and global gene transcription. This function has recently been shown to be under strong selection in Escherichia coli. During the evolution of 12 initially identical populations propagated in a defined environment for 20,000 generations, p...

journal_title：Molecular biology and evolution

authors： Crozat E,Winkworth C,Gaffé J,Hallin PF,Riley MA,Lenski RE,Schneider D

更新日期：2010-09-01 00:00:00

abstract：:Coevolutionary conflict among imprinted genes that influence traits such as offspring growth may arise when maternal and paternal genomes have different evolutionary optima. This conflict is expected in outcrossing taxa with multiple paternity, but not self-fertilizing taxa. MEDEA (MEA) is an imprinted plant gene that...

journal_title：Molecular biology and evolution

authors： Miyake T,Takebayashi N,Wolf DE

更新日期：2009-04-01 00:00:00

abstract：:We determine the phylogenetic backbone of the East Asian mtDNA tree by using published complete mtDNA sequences and assessing both coding and control region variation in 69 Han individuals from southern China. This approach assists in the interpretation of published mtDNA data on East Asians based on either control re...

journal_title：Molecular biology and evolution

authors： Kivisild T,Tolk HV,Parik J,Wang Y,Papiha SS,Bandelt HJ,Villems R

更新日期：2002-10-01 00:00:00