Extracorporeal shockwave therapy for intermittent claudication: Medium-term outcomes from a double-blind randomised placebo-controlled pilot trial.

Abstract:

:Objectives Peripheral arterial disease most commonly presents as intermittent claudication (IC). Early evidence has suggested that extracorporeal shockwave therapy is efficacious in the short term for the management of intermittent claudication. The objective of this pilot trial was to evaluate the medium-term efficacy of this treatment. Methods This double-blind randomised placebo-controlled pilot trial randomised patients with unilateral intermittent claudication in a 1:1 fashion to receive extracorporeal shockwave therapy or a sham treatment for three sessions per week over three weeks. Primary outcomes were maximum walking distance and intermittent claudication distance using a fixed-load treadmill test. Secondary outcomes included pre- and post-exertional ankle-brachial pressure indices, safety and quality of life assessed using generic (SF36, EQ-5D-3L) and disease-specific (vascular quality of life) measures. All outcome measures were assessed at 12 months post-treatment. Results Thirty participants were included in the study (extracorporeal shockwave therapy, n = 15; sham, n = 15), with 26 followed up and analysed at 12 months (extracorporeal shockwave therapy, n = 13; sham, n = 13). Intragroup analysis demonstrated significant improvements in maximum walking distance, intermittent claudication distance and post-exertional ankle-brachial pressure indices ( p < 0.05) in the active treatment group, with no improvements in pre-exertional ankle-brachial pressure indices. Significant improvements in quality of life were observed in 3 out of 19 domains assessed in the active group. A re-intervention rate of 26.7% was seen in both groups. Conclusions These findings suggest that extracorporeal shockwave therapy is effective in improving walking distances at 12 months. Although this study provides important pilot data, a larger study is needed to corroborate these findings and to investigate the actions of this treatment. ISRCTN:NCT02652078.

journal_name

Vascular

journal_title

Vascular

authors

Green JL,Harwood AE,Smith GE,Das T,Raza A,Cayton T,Wallace T,Carradice D,Chetter IC

doi

10.1177/1708538118773618

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

531-539

issue

5

eissn

1708-5381

issn

1708-539X

journal_volume

26

pub_type

杂志文章,随机对照试验

相关文献

Vascular文献大全
  • Optimal prosthetic graft design for small diameter vascular grafts.

    abstract::Autogenous vein and arterial grafts, such as great saphenous veins and internal mammary and radial arteries, remain the gold standard conduits for vascular reconstruction. Expanded polytetrafluoroethylene (PTFE) grafts, which exhibit little inflammatory and thrombogenic reactivity, are the most commonly used material ...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.2310/6670.2007.00053

    authors: Nishibe T,Kondo Y,Muto A,Dardik A

    更新日期:2007-11-01 00:00:00

  • Long-term outcomes and factors influencing late survival following elective abdominal aortic aneurysm repair: A 24-year experience.

    abstract:BACKGROUND:Abdominal aortic aneurysms can be either treated by an open abdominal aortic aneurysm repair or an endovascular repair. Comparing clinical predictors of outcomes and those which influence survival rates in the long term is important in determining the choice of treatment offered and the decision-making proce...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538115586682

    authors: Khashram M,Jenkins JS,Jenkins J,Kruger AJ,Boyne NS,Foster WJ,Walker PJ

    更新日期:2016-04-01 00:00:00

  • Combined percutaneous endovascular iliac angioplasty and infrainguinal surgical revascularization for chronic lower extremity ischemia: preliminary result.

    abstract::The purpose of this study was to evaluate the efficacy of combined ipsilateral percutaneous iliac angioplasty and open infrainguinal surgical techniques for the treatment of patients with multilevel arterial occlusive disease. Combining two types of approaches in the peripheral vascular field is a less aggressive tech...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2010.00007

    authors: Mousa A,Abdel-Hamid M,Ewida A,Saad M,Sahrabi A

    更新日期:2010-03-01 00:00:00

  • Outcomes of endosutured aneurysm repair with the Heli-FX EndoAnchor implants.

    abstract:OBJECTIVE:Endovascular aneurysm repair has gained field over open surgery for the treatment of abdominal aortic aneurysm. However, type Ia endoleak represents a common complication especially in hostile neck anatomy that is recently faced using endoanchors. We conducted a systematic review and meta-analysis to collect ...

    journal_title:Vascular

    pub_type: 杂志文章,meta分析

    doi:10.1177/1708538120923417

    authors: Karaolanis G,Antonopoulos CN,Koutsias S,Antoniou GA,Beropoulis E,Torsello G,Taneva GT,Donas KP

    更新日期:2020-10-01 00:00:00

  • Use of the AngioSculpt scoring balloon for infrapopliteal lesions in patients with critical limb ischemia: 1-year outcome.

    abstract::The AngioSculpt Scoring Balloon Catheter (AngioScore, Inc., Fremont, CA) is composed of a semicompliant balloon encircled by three nitinol spiral struts providing targeted lesion scoring on balloon inflation. Between April 2005 and April 2006, procedural and follow-up data on 31 patients (mean age 76 years; 54.8% male...

    journal_title:Vascular

    pub_type: 杂志文章,多中心研究

    doi:10.2310/6670.2009.00001

    authors: Bosiers M,Deloose K,Cagiannos C,Verbist J,Peeters P

    更新日期:2009-01-01 00:00:00

  • Experimental measurement and mathematical modeling of pulsatile forces on a symmetric, bifurcated endoluminal stent graft model.

    abstract::The objective of this study was to measure the pulsatile forces acting on a symmetric, bifurcated endoluminal stent graft to validate a computational fluid dynamics (CFD) and analytic model so that they can be used for various graft dimensions. We used a load cell to measure the force owing to the movement of an acryl...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2009.00036

    authors: Liffman K,Sutalo ID,Bui A,Lawrence-Brown MM,Semmens JB

    更新日期:2009-07-01 00:00:00

  • Coiling of the brachial artery: an uncommon cause of difficult thrombectomy.

    abstract::Coiling (or looping) of the artery is a rare morphologic entity, most frequently described in the internal carotid artery. In other arteries, coiling is rarely reported because it remains asymptomatic and without clinical relevance unless inadvertently injured, as for diagnostic or monitoring purposes. We present a ca...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1258/rsmvasc.13.4.248

    authors: Ilijevski NS,Jagodic S,Sagic D,Radak D

    更新日期:2005-07-01 00:00:00

  • Glasgow aneurysm score in predicting outcome after ruptured abdominal aortic aneurysm.

    abstract:OBJECTIVE:To assess the ability of Glasgow Aneurysm Score in predicting postoperative mortality for ruptured aortic aneurysm which may assist in decision making regarding the open surgical repair of an individual patient. METHODS:A total of 121 patients diagnosed of ruptured abdominal aortic aneurysm who underwent ope...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538114533539

    authors: Özen A,Unal EU,Mola S,Erkengel I,Kiris E,Aksöyek A,Saritas A,Birincioğlu CL

    更新日期:2015-04-01 00:00:00

  • Use of proximal aortic cuffs as an adjunctive procedure during endovascular aortic aneurysm repair.

    abstract::The purpose of this study was to evaluate the incidence and durability of additional proximal cuffs during endovascular abdominal aortic aneurysm repair (EVAR). A retrospective review of 90 EVAR patients was conducted. Postoperative survival, proximal sealing zone-related complications, and secondary procedures were a...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1258/rsmvasc.13.1.16

    authors: Biebl M,Hakaim AG,Lau LL,Oldenburg WA,Klocker J,Neuhauser B,Paz-Fumagalli R,McKinney JM,Stockland A

    更新日期:2005-01-01 00:00:00

  • Endovascular abdominal aortic aneurysm repair in patients with challenging anatomy: utility of the hybrid endograft.

    abstract::Commercially available aortic stent grafts differ in construction and clinical advantage such that creating hybrid endografts by combining components from different manufacturers is sometimes useful. We describe a multicenter experience using hybrid endografts to treat patients with challenging anatomy. Hospital recor...

    journal_title:Vascular

    pub_type: 杂志文章,多中心研究

    doi:10.1258/rsmvasc.12.2.106

    authors: Jordan WD Jr,Naslund TC,Adelman MA,Simoni G,Wirthlin DJ

    更新日期:2004-03-01 00:00:00

  • Epithelioid hemangioma of the ulnar artery.

    abstract::This case report describes a rare vascular tumor (epithelioid hemangioma) in the ulnar artery of a young male patient, treated by excision and bypass grafting. ...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2010.00043

    authors: Walker SR

    更新日期:2010-09-01 00:00:00

  • Importance of the arteriographic anatomy of the descending genicular artery and sural arteries in patients with atherosclerotic occlusion of the popliteal artery.

    abstract::Bypasses to the descending genicular artery (DGA) or the medial sural artery (MSA) have been performed with acceptable rates of midterm success. The arteriographic appearance of the DGA, the MSA, and the lateral sural artery (LSA) was described and the applicability of bypass to these vessels was investigated. The art...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2006.00043

    authors: Romiti M,Miranda F Jr,Brochado-Neto FC,Kikuchi M,Albers M

    更新日期:2006-07-01 00:00:00

  • Use of duplex guided stent graft placement to prevent bleeding from previously thrombosed pseudo-aneurysms during thrombolytic therapy for acute popliteal artery occlusion.

    abstract::We present a 68-year-old female who developed multiple pseudo-aneurysms (PSAs) following cardiac catheterization via the right groin. During subsequent thrombin injection of PSAs, the patient developed acute occlusion of the popliteal artery. A covered stent was placed to obliterate the PSAs and allow for successful e...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538113499328

    authors: DerDerian T,Hingorani A,Gallagher J,Ascher E

    更新日期:2014-08-01 00:00:00

  • Arterio-biliary fistulas: What to choose as endovascular treatment?

    abstract::Objectives Endovascular procedures are the treatment of choice in cases of intrahepatic fistulas. Arterio-biliary fistulas are the rarest and most difficult to treat, due to high risk of infection. Methods Eight cases of persistent hemobilia that developed as a result of arterio-biliary fistulas are presented. Five ca...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538117743178

    authors: Stefańczyk L,Polguj M,Szubert W,Chrząstek J,Jurałowicz P,Garcarek J

    更新日期:2018-08-01 00:00:00

  • Mortality outcomes of ruptured abdominal aortic aneurysms and rural presentation.

    abstract:OBJECTIVES:Centralisation of vascular surgery services has coincided with a move towards endovascular repair of ruptured abdominal aortic aneurysms with the goal to improve patient outcomes. The aim of this study was to assess the effect of rural presentation and transfer times on survival from ruptured abdominal aorti...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538115599315

    authors: Munday E,Walker S

    更新日期:2016-10-01 00:00:00

  • Management of extremity arterial pseudoaneurysms associated with osteochondromas.

    abstract::Arterial pseudoaneurysms associated with osteochondromas are rare and most publications on this topic are case reports. The management of this double entity is not standardized. We wanted to update it. Literature searches on MEDLINE and EMBASE were performed using the keywords "artery pseudoaneurysm" and "osteochondro...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.1177/1708538116634532

    authors: Raherinantenaina F,Rakoto-Ratsimba HN,Rajaonanahary TM

    更新日期:2016-12-01 00:00:00

  • Assessment of the relation between C-reactive protein to albumin ratio and the severity and complexity of peripheral arterial disease.

    abstract:BACKGROUND:Peripheral arterial disease is associated with increased cardiovascular mortality and morbidity. C-reactive protein and albumin are biomarkers of inflammation and malnutrition that play key roles in the pathophysiological pathways involved in the progression of atherosclerosis and peripheral arterial disease...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538120925952

    authors: Süleymanoğlu M,Burak C,Gümüşdağ A,Yesin M,Rencüzoğulları İ,Karabağ Y,Çağdaş M,Çap M

    更新日期:2020-12-01 00:00:00

  • Radial force measurement of endovascular stents: Influence of stent design and diameter.

    abstract:BACKGROUND AND PURPOSE:Angioplasty and endovascular stent placement is used in case to rescue the coverage of main branches to supply blood to brain from aortic arch in thoracic endovascular aortic repair. This study assessed mechanical properties, especially differences in radial force, of different endovascular and t...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538115590040

    authors: Matsumoto T,Matsubara Y,Aoyagi Y,Matsuda D,Okadome J,Morisaki K,Inoue K,Tanaka S,Ohkusa T,Maehara Y

    更新日期:2016-04-01 00:00:00

  • Perioperative baseline β-blockers: An independent protective factor for post-carotid endarterectomy hypertension.

    abstract:OBJECTIVE:Post-carotid endarterectomy hypertension is a well-recognized phenomenon closely related to surgical complications. This study aimed to determine whether different kinds of perioperative antihypertensive drugs had a protective effect on post-carotid endarterectomy hypertension and influence on intraoperative ...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538120946538

    authors: Teng L,Fang J,Zhang Y,Liu X,Qu C,Shen C

    更新日期:2020-08-09 00:00:00

  • Endovascular repair of arteriovenous fistula after microendoscopic discectomy and lamino-foraminotomy.

    abstract::The last two decades have seen increasing adoption of minimally invasive approaches to lumbar disc herniation management. As with many new advances in surgery, the risk profile of these contemporary approaches has yet to be well defined. We present the case of a 32-year-old man who presented with decreasing exercise t...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538114529762

    authors: Cape H,Balaban DY,Moloney M

    更新日期:2015-02-01 00:00:00

  • Carbon monoxide: vascular therapeutic for the future.

    abstract::In the past decade, carbon monoxide has lost its reputation as a toxic gas and has gained a following of scientists who now appreciate its potential therapeutic utility as an anti-inflammatory and cytoprotective agent. Its vasoprotective properties have also gained a tremendous amount of attention, especially its abil...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.2310/6670.2008.00090

    authors: Tzeng E

    更新日期:2009-05-01 00:00:00

  • A proof-of-concept study of the VeinScrew: A new percutaneous venous closure device.

    abstract::Objective This study evaluated the concept of percutaneous closure of insufficient veins using the VeinScrew principle. Methods The VeinScrew is designed to place a spring-shaped implant that contracts and clamps around the vein. The ability of the device to occlude adequately was tested in a bench model experiment. T...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538116644117

    authors: Boersma D,de Borst GJ,Moll FL

    更新日期:2017-02-01 00:00:00

  • Buerger's disease in the northeast of Iran: Epidemiology and clinical features.

    abstract:BACKGROUND:The aim of this study is to present our long-term clinical experience in describing a clinical picture of Buerger's disease in our region. MATERIALS AND METHODS:In a retrospective study, files of 225 patients who were admitted to the hospital with diagnosis of thromboangiitis obliterans in a 10 year period ...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538114552838

    authors: Modaghegh MH,Kazemzadeh GH,Ravari H,Johari HG,Barzanuni A

    更新日期:2015-10-01 00:00:00

  • Endovascular repair of a pseudoaneurysm of the popliteal artery following arthroscopic knee surgery: case report and review of literature.

    abstract::We report a case of a pseudoaneurysm of the popliteal artery following arthroscopic knee surgery. Endovascular repair was successfully used as the treatment for this patient and studies have shown this to be a safe alternative to surgery. ...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.1177/1708538113477799

    authors: Aburahma Z,Hass SM

    更新日期:2013-04-01 00:00:00

  • A nationwide analysis of 30-day readmissions related to critical limb ischemia.

    abstract::Objectives There is paucity of information regarding critical limb ischemia-related readmission rates in patients admitted with critical limb ischemia. We studied 30-day critical limb ischemia-related readmission rate, its predictors, and clinical outcomes using a nationwide real-world dataset. Methods We did a second...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538117727955

    authors: Masoomi R,Shah Z,Quint C,Hance K,Vamanan K,Prasad A,Hoel A,Dawn B,Gupta K

    更新日期:2018-06-01 00:00:00

  • Modified distal revascularization with interval ligation procedure for steal syndrome after arteriovenous fistula creation for hemodialysis access.

    abstract::Patients diagnosed with steal syndrome after hemodialysis access surgery have a few options for symptom relief while maintaining vascular access. These include fistula lengthening, banding, distal revascularization with interval ligation (DRIL), revision using distal inflow (RUDI) or proximalization of the arterial in...

    journal_title:Vascular

    pub_type: 杂志文章,评审

    doi:10.2310/6670.2007.00047

    authors: van der Meer S,Zeebregts C,Tielliu I,Verhoeven E,van den Dungen J

    更新日期:2007-07-01 00:00:00

  • Changes and significance of T helper-9 cells and interleukin-9 in patients with atherosclerotic chronic lower limb ischemia: Effect on IL-17 release.

    abstract:OBJECTIVES:Atherosclerosis is considered as a chronic inflammatory disorder where the central role of T cells in its pathogenesis is well known. T helper-9 cells have a distinctive effect upon the inflammatory processes. They stimulate macrophages via secretion of their cytokine interleukin-9. Based on its known involv...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538120905430

    authors: Moaaz M,Lotfy H

    更新日期:2020-08-01 00:00:00

  • Prevalence of hyperhomocysteinemia in vascular disease: comparative study of thrombotic venous disease vis-à-vis occlusive arterial disease.

    abstract::Studies on hyperhomocysteinemia in vascular occlusive disease have included mostly patients with arterial occlusion. However, more recent studies have included cases of venous occlusive disease as well. Our present study is aimed at comparing the prevalence of hyperhomocysteinemia in venous occlusive disease vis-à-vis...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2007.00031

    authors: Bhargava S,Parakh R,Manocha A,Ali A,Srivastava LM

    更新日期:2007-05-01 00:00:00

  • High low-density lipoprotein cholesterol level is the independent risk factor of primary patency rate of arteriovenous fistula.

    abstract:OBJECTIVES:An arteriovenous fistula is the first choice of vascular access in dialysis patients. However, the correlations between patient factors and the arteriovenous fistula patency rate remain unclear. Therefore, we examined the effect of dialysis patient factors on arteriovenous fistula patency rate. METHODS:This...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.1177/1708538120905486

    authors: Yamazaki T,Shirai H,Yashima J,Tojimbara T

    更新日期:2020-08-01 00:00:00

  • Predictors of diffuse renal microembolization following endovascular repair of abdominal aortic aneurysms.

    abstract::We evaluated the incidence, risk factors, and clinical consequences of renal microembolic events following endovascular aneurysm repair using suprarenal or infrarenal fixation. Pre- and postoperative (1 month) computed tomographic angiograms were reviewed for new renal perfusion defects. Suprarenal aortic and infraren...

    journal_title:Vascular

    pub_type: 杂志文章

    doi:10.2310/6670.2007.00006

    authors: Boules TN,Stanziale SF,Chomic A,Selzer F,Tublin ME,Makaroun MS

    更新日期:2007-01-01 00:00:00