Abstract:
:The purpose of the present study was to evaluate the recent trend of diagnosing appendiceal diseases through the analysis of appendectomy materials, stressing the importance of their pathological examination. A clinicopathological assessment of patients undergoing an appendectomy was conducted, based on the pathological examination of resected appendiceal lesions. Using a pathological database of surgical specimens from patients who underwent an appendectomy between March 2002 and September 2014, a retrospective, single-center analysis was performed. Among the 803 patients identified, 752 with appendiceal disease were selected for clinicopathological analysis. The diagnosis was inflammation (i.e. appendicitis) in 97.7% (n=735) and appendiceal neoplasm in 2.3% (n=17) of the patients. The most frequent type of appendiceal neoplasm was an intramucosal neoplasm (23.5%, n=4). In conclusion, the incidence of appendiceal neoplasms has increased in recent years, potentially due to increased and earlier detection by newer imaging modalities.
journal_name
Oncol Lettjournal_title
Oncology lettersauthors
Tajima T,Tajiri T,Mukai M,Sugiyama T,Hasegawa S,Yamamoto S,Sadahiro S,Shimada H,Makuuchi Hdoi
10.3892/ol.2018.8134subject
Has Abstractpub_date
2018-05-01 00:00:00pages
6393-6399issue
5eissn
1792-1074issn
1792-1082pii
OL-0-0-8134journal_volume
15pub_type
杂志文章相关文献
Oncology Letters文献大全abstract::Giant cell tumor (GCT) of the bone is a relatively common primary bone tumor. Treatment with simple curettage often results in a high local recurrence rate. Tumor resection and reconstruction with prosthesis or an allograft has a low rate of local recurrence; however, the patient's native joint function becomes signif...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2012.1036
更新日期:2013-02-01 00:00:00
abstract::The present study aimed to retrospectively review the contribution of 18F-fluorodeoxygluose-positron emission tomography/computed tomography (18F-FDG PET/CT) in the assessment of biochemical recurrence in patients with a diagnosis of local-stage prostate cancer (PCa) who underwent radical prostatectomy (RP) or receive...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.3903
更新日期:2016-01-01 00:00:00
abstract::The present study aimed to identify microRNA (miRNA) expression profiles associated with brain metastases of colorectal cancers. We conducted miRNA expression profiling of 3 primary colorectal cancers and 3 brain-metastatic carcinomas using Agilent Human miRNA Microarrays. Quantitative real-time reverse transcription-...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2011.497
更新日期:2012-02-01 00:00:00
abstract::Glucose Transporter 1 (GLUT1) belongs to the expanding mammalian facilitative glucose transporter family. Elevated GLUT1 protein expression has been observed in the majority of urothelial carcinomas, with various effects on clinicopathological parameters. Whereas malignant cells have an accelerated metabolism with inc...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2011.394
更新日期:2011-11-01 00:00:00
abstract::Docetaxel is the current first-line treatment for castration-resistant prostate cancer (CRPC), following failure to respond to maximal androgen blockade (MAB). Patients who fail to respond to docetaxel may receive cabazitaxel or abiraterone; however, there are no recommendations on which of these two agents should be ...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2013.1275
更新日期:2013-06-01 00:00:00
abstract::This study investigated the inhibitory effect of vitamin D-binding protein-derived macrophage-activating factor (GcMAF) on carcinogenesis and tumor growth, using a 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced hamster cheek pouch carcinogenesis model, as well as the cytocidal effect of activated macrophages against ...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2011.306
更新日期:2011-07-01 00:00:00
abstract::A 54-year-old female presented with a large pancreatic tumor of the tail during a regular physical examination. The patient underwent surgical intervention and the surgeon identified that the tumor originated from the retroperitoneal region. Markedly severe hemodynamic fluctuations occurred during the manipulation of ...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2013.1447
更新日期:2013-09-01 00:00:00
abstract::A tissue-specific promoter can control downstream gene expression in tissues or organs. The human involucrin (hINV) promoter (pINV) that contains 2474 bp of hINV upstream sequence is able to regulate tissue-specific gene expression. This tissue specificity may be important for the prevention and treatment of human pap...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2014.2736
更新日期:2015-02-01 00:00:00
abstract::Diagnostic value of magnetic resonance imaging (MRI) and multi-slice spiral CT (MSCT) for different pathological stages of prostate cancer was compared. A total of 112 patients with prostate cancer who underwent surgical pathology in The Affiliated Yantai Yuhuangding Hospital of Qingdao University from February 2014 t...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2019.10272
更新日期:2019-06-01 00:00:00
abstract::Changes in filamin A (FLNa) expression contribute to the development and progression of numerous malignancies. However, in vitro studies of breast cancer have shown conflicting results. Thus, the present study aimed to detect the expression of FLNa in breast cancer tissue samples and the association with clinicopathol...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2013.1454
更新日期:2013-09-01 00:00:00
abstract::Breast tissue is very sensitive to ionizing radiation due to the presence of reproductive hormones, including estrogen. In the present pilot study, the efficiency of mammography X-rays to induce DNA double strand breaks (DSB) in mammary epithelial cells was investigated. For this, freshly resected healthy breast tissu...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.9024
更新日期:2018-09-01 00:00:00
abstract::Pneumocystis jiroveci pneumonia (PCP) has long been recognized as a cause of mortality in immuno-compromised populations, including those with advanced lung cancer. Although Pneumocystis colonization has only recently been described due to the development of more sensitive molecular techniques, including polymerase ch...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2012.1052
更新日期:2013-02-01 00:00:00
abstract::Gliomas are the most common type of primary brain tumor in adults, where more than half of the cases are malignant, and the prognosis is poor. The early viral 1A (E1A) protein has been widely recognized to be essential for adenoviral replication and production of progeny virions in human cells, a process that is regul...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.7684
更新日期:2018-03-01 00:00:00
abstract::Previous studies have revealed several genes involved in the carcinogenesis of oral cancer. However, the detailed mechanisms underlying this process are poorly understood. Previously, we established a database cataloging the transcriptional progression profile of oral carcinogenesis and identified several candidate ge...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2019.10420
更新日期:2019-08-01 00:00:00
abstract::Gastrointestinal stromal tumor (GIST) is the most common type of mesenchymal tumor in the gastrointestinal tract. A large tumor size often means a poor prognosis. This report presents a case of a large exophytic GIST with cyst change, for which the outcome of favourable prognosis was unexpected. A 78-year-old male pre...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2014.1954
更新日期:2014-05-01 00:00:00
abstract::Few reports have explored laparoscopic adnexal tumorectomy as a treatment for large and symptomatic ovarian leiomyomas during pregnancy. The current study presents the case of a patient with a large and symptomatic ovarian leiomyoma at 14 weeks of pregnancy. A laparoscopic adnexal tumorectomy was performed without com...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2014.2596
更新日期:2014-12-01 00:00:00
abstract::MicroRNAs (miRs) have been demonstrated to serve important roles in the development and progression of human cancer, primarily through the direct targeting of oncogenes or tumor suppressors. It has been previously suggested that miR-126 may be associated with endometrial cancer (EC). However, the exact role of miR-126...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.4001
更新日期:2016-02-01 00:00:00
abstract::Local adjuvant treatment of giant cell tumours (GCTs) of the bone with phenol has led to a significant reduction in recurrence rates. In the current study, the optimal phenol concentration and duration of intralesional exposure were evaluated. Specimens of GCTs were exposed to various concentrations of phenol solution...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2013.1244
更新日期:2013-05-01 00:00:00
abstract::The CyberKnife® is expected to be a novel local treatment for hepatocellular carcinoma (HCC), however, a long-term follow-up using dynamic computed tomography and magnetic resonance imaging is required to determine the effect of treatment in a number of the affected patients. Therefore, there is a requirement to evalu...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2015.3874
更新日期:2016-01-01 00:00:00
abstract::Wild-type p53-induced phosphatase (Wip1) is a member of the protein phosphatase type 2C family and is an established oncogene due to its dephosphorylation of several tumor suppressors and negative control of the DNA damage response system. It has been reported to dephosphorylate p53, ataxia telangiectasia mutated, che...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.6685
更新日期:2017-10-01 00:00:00
abstract::Despite the efficacy of combination chemotherapy with arsenic trioxide (ATO), interferon α (IFN) and zidovudine (AZT) for adult T cell leukemia/lymphoma (ATL), the precise mechanism underlying this combination treatment effect is unknown. In the present study, ATO/IFN/AZT was examined in an ATL leukemic cell line (S1T...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2018.8771
更新日期:2018-07-01 00:00:00
abstract::The current study presents a case of primary T-cell lymphoma (PTBL), unspecified, in a 27-year-old female. The patient received chemotherapy [cyclophosphamide, epirubicin, vindesine and prednisolone (CHOP) and VP-16 plus CHOP (ECHOP)] and autologous peripheral blood stem cell transplantation, however, relapse occurred...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2013.1676
更新日期:2014-01-01 00:00:00
abstract::The expression levels of α-enolase, also known as enolase 1 (ENO1), in liver cancer tissues and the autoantibody levels of ENO1 in the sera of patients with liver cancer were detected to investigate the function of ENO1 in the invasion and metastasis of liver cancer, as well as its clinical diagnostic value. Small int...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2020.12003
更新日期:2020-11-01 00:00:00
abstract::The present study selected and characterized a multidrug-resistant HL-60 human acute promyelocytic leukemia cell line, HL-60/RS, by exposure to stepwise incremental doses of doxorubicin. The drug-resistant HL-60/RS cells exhibited 85.68-fold resistance to doxorubicin and were cross-resistant to other chemotherapeutics...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.7353
更新日期:2018-01-01 00:00:00
abstract::The extremely delicate shift from an inflammatory process to tumorigenesis is a field of major scientific interest. While the inflammation induced by environmental agents has well known underlying mechanisms, less is known concerning the oncogenic changes that follow an inflammatory chronic status in the tissue microe...
journal_title:Oncology letters
pub_type: 杂志文章,评审
doi:10.3892/ol.2018.9735
更新日期:2019-05-01 00:00:00
abstract::Curcumin (CUR) has been demonstrated to protect against carcinogenesis and to prevent tumor development in cancer; however, the clinical application of CUR is limited by its instability and poor metabolic properties. The present study offers an strategy for a novel CUR analogue, (1E,4E)-1,5-bis(2-bromophenyl)penta-1,4...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2016.5126
更新日期:2016-11-01 00:00:00
abstract::The present study aimed to identify the regulatory mechanisms associated with the metastasis of prostate cancer (PC). The microRNA (miRNA/miR) microarray dataset GSE21036 and gene transcript dataset GSE21034 were downloaded from the Gene Expression Omnibus database. Following pre-processing, differentially expressed m...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.6969
更新日期:2017-11-01 00:00:00
abstract::The clinical resistance of non-small cell lung cancer (NSCLC) to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) has been linked to EGFR T790M resistance mutations or MET amplifications. Additional mechanisms underlying EGFR-TKI drug resistance remain unclear. The present study demonstrated t...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2017.5829
更新日期:2017-05-01 00:00:00
abstract::The present study aimed to explore the diagnostic and prognostic value of lncRNA maternally expressed 3 (MEG3) in cervical cancer. Eighty-four patients with cervical cancer from February 2013 to March 2014 were enrolled in the observation group (OG), and another 58 female subjects who underwent physical examination at...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2020.12044
更新日期:2020-11-01 00:00:00
abstract::The development of drug resistance to chemotherapeutic agents has consistently presented a challenge in terms of the treatment of patients with triple-negative breast cancer (TNBC). In the present study, gemcitabine (dFdC)-resistant TNBC cells were established, and the effects of lentivirus-deoxyribonucleoside kinase ...
journal_title:Oncology letters
pub_type: 杂志文章
doi:10.3892/ol.2020.12109
更新日期:2020-11-01 00:00:00