The Novel Phage-Derived Antimicrobial Agent HY-133 Is Active against Livestock-Associated Methicillin-Resistant Staphylococcus aureus.

Abstract:

:Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) isolates are increasingly migrating from livestock into human and animal health care settings. Alternative substances are needed to overcome the drawbacks of currently available drugs used for MRSA eradication. The recombinant bacteriophage endolysin HY-133 has proved to be an active agent against S. aureus Here, the in vitro activity of HY-133 was studied against a large collection of genetically diverse LA-MRSA isolates revealing its high activity against mecA-, mecB-, and mecC-positive LA-MRSA.

authors

Kaspar U,de Haro Sautto JA,Molinaro S,Peters G,Idelevich EA,Becker K

doi

10.1128/AAC.00385-18

subject

Has Abstract

pub_date

2018-06-26 00:00:00

issue

7

eissn

0066-4804

issn

1098-6596

pii

AAC.00385-18

journal_volume

62

pub_type

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