Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report.

Abstract:

INTRODUCTION:The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients. METHODS:In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA. RESULTS:Fas2-ELISA demonstrated negative results in all HCC patients included in this study. CONCLUSIONS:The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.

journal_name

Rev Soc Bras Med Trop

authors

Machicado C,Bertani S,Herrera-Velit P,Espinoza J,Ruiz E,Marcos L

doi

10.1590/0037-8682-0180-2017

subject

Has Abstract

pub_date

2018-03-01 00:00:00

pages

231-233

issue

2

eissn

0037-8682

issn

1678-9849

pii

S0037-86822018000200231

journal_volume

51

pub_type

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