Synthesis of bioactive compounds from vermicast isolated actinomycetes species and its antimicrobial activity against human pathogenic bacteria.

abstract：:Toxoplasma gondii is one of the most successful intracellular protozoan parasites in the world, which can infect most warm-blooded animals including foxes in the world and cause toxoplasmosis. This is the first meta-analysis to assess the overall prevalence and potential risk factors of T. gondii among foxes in the wo...

journal_title：Microbial pathogenesis

authors： Wei XY,Gao Y,Lv C,Wang W,Chen Y,Zhao Q,Gong QL,Zhang XX

更新日期：2020-12-28 00:00:00

abstract：:Sigma factor B (SigB) controls the expression of Staphylococcus aureus genes including virulence factors and plays a role in the bacterial secretion system through membrane vesicle production. Inhibition of SigB could attenuate SigB dependent virulence and secretion system. The objective of this study was to determine...

journal_title：Microbial pathogenesis

authors： Mitsuwan W,Jiménez-Munguía I,Visutthi M,Sianglum W,REIPI\/GEIH Study Group.,Rodríguez-Ortega MJ,Voravuthikunchai SP

更新日期：2019-03-01 00:00:00

abstract：:In the Staphylococcus aureus ATCC25923 strain, the flqB mutation in the 5'untranslated region (5'UTR) of the norA gene causes increased norA mRNA expression and high efflux activity (HEA). The involvement of the norA gene 5'UTR in HEA has not been explored in S. epidermidis; therefore, we examined the function of this...

journal_title：Microbial pathogenesis

authors： García-Gómez E,Jaso-Vera ME,Juárez-Verdayes MA,Alcántar-Curiel MD,Zenteno JC,Betanzos-Cabrera G,Peralta H,Rodríguez-Martínez S,Cancino-Díaz ME,Jan-Roblero J,Cancino-Diaz JC

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:It is generally considered that HLA-Ⅱ genes contribute to the Helicobacter pylori (Hp) infection and disease development process. AIMS:To perform a meta-analysis to explore the relationship between HLA-Ⅱgene polymorphism and host susceptibility to Hp infection. METHODS:Relevant cohort studies, case-control...

journal_title：Microbial pathogenesis

authors： Wang J,Zhang Q,Liu Y,Han J,Ma X,Luo Y,Liang Y,Zhang L,Hu Y

更新日期：2015-05-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is a common cause of hospital-acquired infection and has become an epidemic globally. Alpha-haemolysin (α-haemolysin), a pore-forming toxin, is one of the most important virulence factors secreted by most S. aureus strains. α-haemolysin monomers form a 232.4-kDa membrane-inserted hept...

journal_title：Microbial pathogenesis

authors： Zhou Y,Chen C,Pan J,Deng X,Wang J

更新日期：2018-02-01 00:00:00

abstract：:HPV persistent infection is a main event leading to the development of cervical intraepithelial neoplasia and cervical cancer. Earlier to distinguish HPV persistent and transient infection is meaningful but the methods are limited. This study used 16S rDNA sequencing to determine the cervicovaginal microbiota of HPV p...

journal_title：Microbial pathogenesis

authors： Qingqing B,Jie Z,Songben Q,Juan C,Lei Z,Mu X

更新日期：2020-11-15 00:00:00

abstract：:Enteropathogenic Escherichia coli (EPEC) uses a type III secretion system (T3SS) to inject effectors into host cells and alter cellular physiology. The aim of the present study was to identify targets of human secretory immunoglobulin A (sIgA) antibodies from the proteins delivered by EPEC into HEp-2 cells after infec...

journal_title：Microbial pathogenesis

authors： Gavilanes-Parra S,Mendoza-Hernández G,Chávez-Berrocal ME,Girón JA,Orozco-Hoyuela G,Manjarrez-Hernández A

更新日期：2013-11-01 00:00:00

abstract：:The clinical implications of recently discovered porcine circovirus 3 (PCV3) infections are still unknown. The potential role of this emerging virus in reproductive loss in swine has been described. Herein, we report a high prevalence of PCV3 in mummified fetuses from sows maintained in modern farms in Rio Grande do S...

journal_title：Microbial pathogenesis

authors： Dal Santo AC,Cezario KC,Bennemann PE,Machado SA,Martins M

更新日期：2020-04-01 00:00:00

abstract：:Anthrax lethal factor (LF), a Zn(2+)-dependent metalloprotease, is a key virulence component of anthrax toxin. Here, we used proteolytic assay-based screening to identify novel LF inhibitors from a naturally extracted chemical library. The screening identified four compounds that inhibited in vitro proteolytic activit...

journal_title：Microbial pathogenesis

authors： Park HC,Sung SR,Lim SM,Lee JS,Kim SK,Yoon MY

更新日期：2012-08-01 00:00:00

abstract：:Clostridium difficile causes serious and potentially fatal inflammatory diseases of the colon. Two large protein toxins, TcdA and TcdB, have been clearly implicated in pathogenesis. The goal of this study was to determine whether the glucosyltransferase activity of the toxins is critical for the induction of tumor nec...

journal_title：Microbial pathogenesis

authors： Sun X,He X,Tzipori S,Gerhard R,Feng H

更新日期：2009-06-01 00:00:00

abstract：:The involvement of nitric oxide (NO) in host defense and cytoprotective functions in murine salmonellosis has been reported. Salmonella mutants with the altered sigma factor RpoS (sigmaS) are less virulent and are susceptible to various stresses. This study investigated the role of the rpoS gene of Salmonella enterica...

journal_title：Microbial pathogenesis

authors： Alam MS,Zaki MH,Yoshitake J,Akuta T,Ezaki T,Akaike T

更新日期：2006-03-01 00:00:00

abstract：:The antigenic site normally situated in the EF loop of VP2 (2EF) of poliovirus type 2 (Lansing) [PV2 (L)] was expressed in 2EF or in the BC loop of VP1 (1BC) of PV1 (Mahoney) [PV1 (M)]. A hybrid virus expressing the site in 2EF of PV1 (M) is known to be neutralizable by PV2 (L)-specific antisera and to induce neutrali...

journal_title：Microbial pathogenesis

authors： Murdin AD,Mirzayan C,Kameda A,Wimmer E

更新日期：1991-01-01 00:00:00

abstract：:Staphylococcus aureus (S. aureus) is one of several opportunistic microbial pathogens associated with many healthcare problems. In the present study, S. aureus was assessed for its biofilm-forming ability on materials routinely used in dental offices, including stainless steel (SS), polyethylene (PE), and polyvinyl ch...

journal_title：Microbial pathogenesis

authors： Merghni A,Bekir K,Kadmi Y,Dallel I,Janel S,Bovio S,Barois N,Lafont F,Mastouri M

更新日期：2017-02-01 00:00:00

abstract：:Listeriosis is a serious infection linked to the consumption of food contaminated with Listeria monocytogenes. Outbreaks and mortality rates associated with this infection make it a significant public health concern. As biocontrol agents, probiotics such as Lactobacillus plantarum had been of interest for the promotio...

journal_title：Microbial pathogenesis

authors： Mohammadzadeh R,Azadegan A,Kalani BS

更新日期：2019-12-01 00:00:00

abstract：:The objective of this paper was to evaluate NTPDase and 5'-nucleotidase activities in platelets of bovine with and without spleen and infected by Anaplasma marginale. Our results demonstrate that infection along with splenectomy is able of inducing a profile of cellular protection, which showed an increase in the degr...

journal_title：Microbial pathogenesis

authors： Doyle RL,Oliveira CB,França RT,Doleski PH,Souza VC,Leal DBR,Martins JR,Lopes STA,Machado G,Da Silva AS,Andrade CM

更新日期：2016-06-01 00:00:00

abstract：:Molecular prevalence of nine putative virulence factors in two more prevalent Brucella species in Iranian patients and livestock was investigated. During five years (2010-2015), 120 human and animal specimens were collected from three geographical areas of Iran. All samples were cultured in blood culture media and sub...

journal_title：Microbial pathogenesis

authors： Hashemifar I,Yadegar A,Jazi FM,Amirmozafari N

更新日期：2017-04-01 00:00:00

abstract：:Carbapenem, imipenem and meropenem have been broadly prescribed contributing to the global occurrence and prevalence of carbapenem resistance in Psuedomonas aeruginosa, and the associated resistance genotypes remains clinically significant. A retrospective surveillance had been conducted on 499 P. aeruginosa isolates ...

journal_title：Microbial pathogenesis

authors： Yu G,Wen W,Peters BM,Liu J,Ye C,Che Y,Liu J,Cao K,Xu Z,Shirtliff ME

更新日期：2016-06-01 00:00:00

abstract：:Pathogenic Salmonella strains have a set of virulence factors allowing them to generate systemic infections and damage in a variety of hosts. Among these factors, bacterial proteins secreted by specialized systems are used to penetrate the host's intestinal mucosa, through the invasion and destruction of specialized e...

journal_title：Microbial pathogenesis

authors： Varas M,Ortíz-Severín J,Marcoleta AE,Díaz-Pascual F,Allende ML,Santiviago CA,Chávez FP

更新日期：2017-06-01 00:00:00

abstract：:The exfoliative toxin produced by Staphylococcus hyicus strain 1289D-88 was purified as a single protein of approximately 30 kDa. Extracellular proteins of S. hyicus grown under small scale fermentation conditions were precipitated with ammonium sulfate. Separation of proteins was performed by hydrophobic interaction ...

journal_title：Microbial pathogenesis

authors： Andresen LO,Bille-Hansen V,Wegener HC

更新日期：1997-02-01 00:00:00

abstract：:Because of the close genetic relatedness between apes and humans, apes are susceptible to many human infectious agents and can serve as carriers of these pathogens. Consequently, they present a serious health hazard to humans. Moreover, many emerging infectious diseases originate in wildlife and continue to threaten h...

journal_title：Microbial pathogenesis

authors： Keita MB,Hamad I,Bittar F

更新日期：2014-12-01 00:00:00

abstract：:In the amino acid (AA) sequences of alpha antigen from mycobacteria, C-terminal regions were variable among a variety of mycobacterial species though the N-terminal regions were relatively conserved. These regions may possess some species-specific antigenic determinants of the alpha antigen from Mycobacterium scrofula...

journal_title：Microbial pathogenesis

authors： Takano M,Ohara N,Naito M,Matsumoto S,Matsuo T,Shirai R,Mizuno A,Yamada T

更新日期：1997-08-01 00:00:00

abstract：:Protective immunity against Salmonella infection was studied in a mouse model. To study specificity of protection we used smooth (O-4,5,12) and rough vaccines; live and killed vaccines of both types were compared. The protection was assessed by enumerating the number of bacteria in the livers, and by following surviva...

journal_title：Microbial pathogenesis

authors： Muotiala A,Hovi M,Mäkelä PH

更新日期：1989-01-01 00:00:00

abstract：:Hemoparasitic diseases like trypanosomiasis have an adverse influence on the health and working capability of infected animals. Monitoring and identification of blood born parasitic infections in dairy animals are of vital importance to get the optimum production. In this study blood samples were collected from Nili R...

journal_title：Microbial pathogenesis

authors： Hussain R,Khan A,Jahanzaib,Qayyum A,Abbas T,Ahmad M,Mohiuddin M,Mehmood K

更新日期：2018-10-01 00:00:00

abstract：:The macrophage innate immune response is outlined through recognition of the components of Mycobacterium tuberculosis. DNA of M. tuberculosis (MtbDNA) is recognized by macrophages, but the implications of this recognition are poorly characterized. Stimulation of murine macrophages with MtbDNA induces autophagy, a proc...

journal_title：Microbial pathogenesis

authors： Ruiz A,Guzmán-Beltrán S,Carreto-Binaghi LE,Gonzalez Y,Juárez E

更新日期：2019-07-01 00:00:00

abstract：:Repetitive tetranucleotide sequences of 5'-(CAAT)(n)-3' have been identified at the 5' end of an open reading frame (ORF) named lob1 from Haemophilus somnus strain 738. Based on sequence analysis, lob1 has 59% DNA homology to lex2B, which is involved in lipooligosaccharide (LOS) biosynthesis in H. influenzae. We now r...

journal_title：Microbial pathogenesis

authors： McQuiston JH,McQuiston JR,Cox AD,Wu Y,Boyle SM,Inzana TJ

更新日期：2000-05-01 00:00:00

abstract：:Vibrio cholerae elaborates zonula occludens toxin (Zot), a protein that increases the permeability of small intestinal mucosa by opening intercellular tight junctions. The zot gene is located, together with the genes encoding CT and Ace enterotoxins, within the genome of V. cholerae filamentous phage CTXsmall ef, Cyri...

journal_title：Microbial pathogenesis

authors： Uzzau S,Cappuccinelli P,Fasano A

更新日期：1999-12-01 00:00:00

abstract：:Helicobacter pylori is a microorganism that in the last years has been associated with extragastric disorders such as respiratory diseases, however, its impact on lung is partially understood. The aim of this work was to study infection impact of H. pylori on the inflammatory markers expression at the pulmonary level ...

journal_title：Microbial pathogenesis

authors： Arismendi Sosa AC,Salinas Ibáñez AG,Pérez Chaca MV,Penissi AB,Gómez NN,Vega AE

更新日期：2020-02-26 00:00:00

abstract：:The present study characterizes immune cell populations in mice chronically infected with Salmonella. Mice were characterized as chronically infected based on persistently high titers of Salmonella-reactive immunoglobulins in the serum >6 months after a single oral dose of S. enterica serovar Typhimurium. These mice h...

journal_title：Microbial pathogenesis

authors： Johansson C,Ingman M,Jo Wick M

更新日期：2006-08-01 00:00:00

abstract：:The biodegradation of Aflatoxin B1 (AFB1) is an industry of increasing importance. Bacillus licheniformis BL-010 was isolated from the aflatoxin contaminated corn feed storage, and was shown to degrade AFB1 efficiently. Here we present the complete genome sequence of BL-010, the genome comprises 4,287,714 bp in a circ...

journal_title：Microbial pathogenesis

authors： He S,Feng K,Ding T,Huang K,Yan H,Liu X,Zhang Z

更新日期：2018-05-01 00:00:00

abstract：:Bovine leukemia virus (BLV) is transcriptionally silent in most circulating peripheral blood mononuclear cells (PBMCs) of animals with well-established infections. Using PBMCs from a newly infected sheep, we asked whether viral transcription proceeded differently during the initial months of infection, when the preval...

journal_title：Microbial pathogenesis

authors： Radke K,Sigala TJ,Grossman D

更新日期：1992-05-01 00:00:00