Abstract：
:Management of head and neck cancer in the elderly patient is particularly challenging given the high morbidity associated with treatment. Surgery, radiotherapy, and chemotherapy have all been demonstrated as effective in older patients; however, older patients are more susceptible to treatment-induced toxicity, which can limit the survival benefits of certain interventions. This susceptibility is better associated with the presence of multiple comorbidities and decreasing functional status than with age alone. Screening tools allow for risk stratification, treatment deintensification, and even treatment avoidance in patients who are deemed at high-risk of being harmed by standard therapy.
journal_name
Otolaryngol Clin North Amjournal_title
Otolaryngologic clinics of North Americaauthors
Cervenka BP,Rao S,Bewley AFdoi
10.1016/j.otc.2018.03.004subject
Has Abstractpub_date
2018-08-01 00:00:00pages
741-751issue
4eissn
0030-6665issn
1557-8259pii
S0030-6665(18)30051-3journal_volume
51pub_type
杂志文章,评审abstract：:It is essential for laryngologists, speech and language pathologists, and others caring for professional voice users to be familiar with the potential vocal effects of any substance ingested by a professional voice patient. This article reviews pharmacologic agents that may have laryngeal side effects. Essentially, an...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：10.1016/s0030-6665(05)70243-7
更新日期：2000-08-01 00:00:00
abstract：:This article is a comprehensive overview of tympanic membrane injury and its healing. Its wound healing process is unique from soft tissue because epithelialization occurs before fibrous tissue advancement. Contemporary and future modalities to improve tympanic membrane repair are also discussed in this article. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：:Polysomnography provides information on the physiological changes occurring in many different organ systems in relation to sleep stages and wakefulness. It allows qualitative and quantitative documentation of abnormalities of sleep and wakefulness, of sleep-wake transition, and of physiological function of other organ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2007.04.003
更新日期：2007-08-01 00:00:00
abstract：:A patient seeking emergency treatment for a labyrinthine disorder is usually complaining of dizziness. The task at hand in the emergency room is, first, to rule out the truly life threatening emergent disorders, and then by means of a rapid but adequate history and physical examination to aid in the differentiation be...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:Laryngeal inflammation includes a broad spectrum of pathologies, from infectious processes that need to be managed as airway emergencies, to indolent diseases that mimic head and neck cancer. The importance of a thorough history cannot be emphasized enough as it is the most important step toward developing a different...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2007.11.012
更新日期：2008-04-01 00:00:00
abstract：:Temporal arteritis is generally a benign and self-limiting disease, which has been recognized for approximately 50 years. Although it has been uncommon, it is becoming increasingly prevalent among elderly individuals. Its major complication involves loss of vision, and approximately 50 per cent of all untreated patien...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1982-08-01 00:00:00
abstract：:The nasal septum is a structure poorly understood and appreciated by the lay public and the nonotolaryngologist--head and neck surgeon alike. Deviation of the caudal portion of the nasal septum may result in nasal obstruction, a crooked nose, and columellar irregularities. The correction of a severely deviated caudal ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2009.03.005
更新日期：2009-06-01 00:00:00
abstract：:This article provides guidelines for pharmacotherapy to maximize symptom relief from allergic rhinitis. Consideration of frequency, severity, and site of symptoms is important in directing pharmacotherapy efficacy and maximizing cost-effectiveness. The agents available include antihistamines, decongestants, steroids, ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(05)70032-3
更新日期：1998-02-01 00:00:00
abstract：:Olfactory loss can occur through accidental exposure, poor industrial hygiene, or exposure to low levels of toxins in the ambient air over long periods. This loss can lead to transient olfactory disorders, irreversible anosmia, temporary olfactory fatigue, or industrial anosmia. Inevitably, a practicing otolaryngologi...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2004.05.003
更新日期：2004-12-01 00:00:00
abstract：:The past 20 years have seen the cochlear implant evolve from an innovative but radical concept to the standard of care in the management of children with severe to profound hearing loss. All children receiving the cochlear implant achieve substantial benefit; however, performance gains are optimized by a team approach...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0030-6665(02)00059-2
更新日期：2002-08-01 00:00:00
abstract：:Cancer of the ear is similar, in many respects, to cancer of other skin-covered parts of the body. The aggressive nature of malignancies involving the ear is often underestimated, resulting in initial undertreatment. Later, the price is paid when a much more extensive operation is required to exenterate the cancer. A ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-04-01 00:00:00
abstract：:Reconstruction of craniomaxillofacial defects caused by injury, tumor ablation, or congenital deformities can be accomplished by a variety of methods. Nonvascularized (free), vascularized (pedicled), and revascularized (microvascular) bone grafts have been employed for osseous restoration of the upper, mid, and lower ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1994-10-01 00:00:00
abstract：:Pharmacologic labyrinthectomy has become an alternative to surgery for treatment of severe Ménièr's disease. The use of systemic streptomycin has been replaced by intratympanal instillations of gentamicin that are administered once daily for a limited number of days. Gentamicin provides a high success rate for ablatio...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1994-04-01 00:00:00
abstract：:The majority of recurrent thyroid carcinomas are histologically differentiated and readily diagnosed by light microscopy or immunohistochemical staining. Infrequently, recurrent carcinoma may be less differentiated than the index lesion, creating diagnostic challenges. Complicating issues include thyroid carcinomas th...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.08.001
更新日期：2008-12-01 00:00:00
abstract：:The endoscopic approach to stapes surgery affords unique advantages but is not without its specific challenges. The following reviews the equipment and surgical steps required to perform endoscopic stapes surgery safely and effectively, highlighting tips and potential points of failure through a series of case example...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2020.09.015
更新日期：2021-02-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) contributes to the development of many otolaryngologic symptoms and conditions, including chronic throat clearing, cough, sore throat, contact ulcer and granuloma, globus pharyngeus, cervical dysphagia, cancer of the larynx, subglottic stenosis, and cricoarytenoid arthritis. Thes...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1991-10-01 00:00:00
abstract：:This article discusses the use of an integrative approach in the evaluation and management of the voice. The article begins with a look at the larynx and antioxidant therapy, followed by methods to relieve the pain associated with myofacial trigger points, and the herbs and supplements that can be used by vocalists to...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2013.02.008
更新日期：2013-06-01 00:00:00
abstract：:The mechanism of development of rupture of the round window membrane appears to be an increase in pressure in the cerebrospinal fluid transmitted to the inner ear via the cochlear aqueduct. Two cases of rupture of the round window membrane in divers are described in detail. One diver had ruptures of both round window ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:With an unknown or occult primary cancer, the clinical presentation can be either undiagnosed lump or lumps in the neck that has been biopsied and diagnosed as metastatic cancer on the basis of the histopathologic findings. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1985-08-01 00:00:00
abstract：:Minimally invasive sinus technique (MIST) is a targeted endoscopic intervention, introduced in 1994, with goals virtually identical to those originally reported for FESS but with distinct differences. The procedure, as outlined in the following section, is the only stepwise intranasal intervention with a defined begin...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/S0030-6665(03)00156-7
更新日期：2004-04-01 00:00:00
abstract：:The historical context for quality improvement is provided. Important differences are described between the two overarching types of databases: clinical registries and administrative databases. The pros and cons of each are provided as are examples of their utilization in otolaryngology-head and neck surgery. ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2018.08.004
更新日期：2019-02-01 00:00:00
abstract：:Endoscopic endonasal skull base surgical techniques, initially developed in adult patients, are being utilized with increasing frequency in pediatric patients to treat sinonasal and skull base lesions. This article reviews the current state of endoscopic endonasal approaches to the skull base to both treat disease and...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2014.09.007
更新日期：2015-02-01 00:00:00
abstract：:Simulation is rapidly expanding across medicine as a valuable component of trainee education. For procedural simulation, development of low-cost simulators that allow a realistic, haptic experience for learners to practice maneuvers while appreciating anatomy has become highly valuable. Otolaryngology has seen signifi...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2017.05.006
更新日期：2017-10-01 00:00:00
abstract：:Active auditory implants, such as the Maxum, provide significantly improved hearing function compared to hearing aids in patients with moderate to severe hearing loss who are not reaching their cochlear hearing potential. The speech perception gap (SPG), defined as PB Max (phonetically balanced maximum) minus word rec...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2018.11.014
更新日期：2019-04-01 00:00:00
abstract：:Craniofacial disassembly now plays a major role in the management of tumors that invade the skull base. The chief advantage of this technique is the greatly improved operative exposure it provides, allowing the surgeon to resect such tumors more completely and with an added margin of safety. Microneurosurgical advance...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:The use of minimally invasive and endoscopic thyroidectomy techniques has become widespread. However, these procedures all result in a visible neck incision. Several remote access thyroidectomy approaches that place the necessary incision in inconspicuous, noncervical locations have recently been described. Robotic fa...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2014.02.001
更新日期：2014-06-01 00:00:00
abstract：:Among the several risks encountered in endoscopic sinus surgery, catastrophic orbital bleeding and iatrogenic cerebrospinal fluid leak are the two serious complications surgeons most fear. This article discusses these avoidable complications and provides treatment algorithms for intraoperative maneuvers. A thorough un...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2008.01.005
更新日期：2008-06-01 00:00:00
abstract：:Endoscopic pituitary surgery has been gaining wide acceptance as the first-line treatment of most functional pituitary adenomas. This technique has many advantages over traditional procedures, and growing evidence supports its use for endocrine control of functioning tumors. This article reviews data on the different ...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2011.06.019
更新日期：2011-08-01 00:00:00
abstract：:As cochlear implant technology has changed, so have implantation criteria. In addition to profoundly deaf individuals, candidacy has expanded to include those with significant remaining acoustic hearing. This article describes the devices that are now in clinical trial, discusses the rationale as to why residual heari...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.otc.2011.09.001
更新日期：2012-02-01 00:00:00
abstract：:This article reviews the most commonly performed intranasal and extranasal sinus operations. The indications, complications, and functional results of each are presented. Endoscopic approaches should be used in conjunction with standard techniques in order to supplement and improve the efficiency of standard technique...
journal_title：Otolaryngologic clinics of North America
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
