Validation of reference and identity-defining genes in human mesenchymal stem cells cultured under unrelated fetal bovine serum batches for basic science and clinical application.

abstract：:The original version of this article unfortunately contained a mistake. In the author group, the correct family name of Dr. Rebeca is "Blázquez" and the correct family name of Dr. Francisco Miguel is "Sánchez-Margallo." ...

journal_title：Stem cell reviews and reports

authors： López E,Blázquez R,Marinaro F,Álvarez V,Blanco V,Báez C,González I,Abad A,Moreno B,Sánchez-Margallo FM,Crisóstomo V,Casado JG

更新日期：2020-06-01 00:00:00

abstract：:The combination of cell therapy with growth factors could be a useful approach to treat progressive muscular dystrophies. Here, we demonstrate, for the first time, that IGF-1 considerably enhances the myogenesis of human umbilical cord (UC) mesenchymal stromal cells (MSCs) in vitro and that IGF-1 enhances interaction ...

journal_title：Stem cell reviews and reports

authors： Secco M,Bueno C Jr,Vieira NM,Almeida C,Pelatti M,Zucconi E,Bartolini P,Vainzof M,Miyabara EH,Okamoto OK,Zatz M

更新日期：2013-02-01 00:00:00

abstract：:Pre-clinical studies have supported the use of mesenchymal stem cells (MSC) to treat highly prevalent neurodegenerative diseases such as Parkinson's disease (PD) but preliminary trials have reported controversial results. In a rat model of PD induced by MPTP neurotoxin, we first observed a significant bilateral preser...

journal_title：Stem cell reviews and reports

authors： Pereira MC,Secco M,Suzuki DE,Janjoppi L,Rodini CO,Torres LB,Araújo BH,Cavalheiro EA,Zatz M,Okamoto OK

更新日期：2011-11-01 00:00:00

abstract：:The practice of travelling abroad to receive unproven and unregulated stem cell treatments has become an increasingly problematic global phenomenon known as 'stem cell tourism'. In this paper, we examine representations of nine major clinics and providers of such treatments on the microblogging network Twitter. We col...

journal_title：Stem cell reviews and reports

authors： Kamenova K,Reshef A,Caulfield T

更新日期：2014-12-01 00:00:00

abstract：:The discovery of induced pluripotent stem (iPS) cells in 2006 marked a major breakthrough in regenerative medicine, enabling reversal of terminally differentiated somatic cells into pluripotent stem cells. The embryonic stem (ES) cells-like pluripotency and unlimited self-renewal capability of iPS cells have granted t...

journal_title：Stem cell reviews and reports

authors： Khoo TS,Jamal R,Abdul Ghani NA,Alauddin H,Hussin NH,Abdul Murad NA

更新日期：2020-04-01 00:00:00

abstract：:Converting adult cells from one cell type to another is a particularly interesting idea for regenerative medicine. Terminally differentiated cells can be induced to de-differentiate in vitro to become multipotent progenitors. In mammals these changes do not occur naturally, however exposing differentiated adult cells ...

journal_title：Stem cell reviews and reports

authors： Brevini TA,Pennarossa G,Rahman MM,Paffoni A,Antonini S,Ragni G,deEguileor M,Tettamanti G,Gandolfi F

更新日期：2014-10-01 00:00:00

abstract：:Stem cells in the endometrium and myometrium possess an immense regenerative potential which is necessary to maintain the menstrual cycle and support pregnancy. These cells, as well as bone marrow stem cells, have also been implicated in the development of common benign gynecological disorders including leiomyomas, en...

journal_title：Stem cell reviews and reports

authors： El Sabeh M,Afrin S,Singh B,Miyashita-Ishiwata M,Borahay M

更新日期：2020-11-05 00:00:00

abstract：:The absence of effective and satisfactory treatments that contribute to repairing the dopaminergic damage caused by Parkinson's Disease (PD) and the limited recovery capacity of the nervous system are troubling issues and the focus of many research and clinical domains. Recent advances in the treatment of PD through s...

journal_title：Stem cell reviews and reports

authors： Hurtado JDC,Sánchez JPB,Nunes RB,de Oliveira AA

更新日期：2018-04-01 00:00:00

abstract：:Adipogenesis is a complex process whereby the multipotent adipose-derived stem cell is converted to a preadipocyte before terminal differentiation into the mature adipocyte. Preadipocytes are present throughout adult life, exhibit adipose fat depot specificity, and differentiate and proliferate from distinct progenito...

journal_title：Stem cell reviews and reports

authors： Sarantopoulos CN,Banyard DA,Ziegler ME,Sun B,Shaterian A,Widgerow AD

更新日期：2018-02-01 00:00:00

abstract：:The vertebrate early stage embryo is consisting of the three primary germ layers ectoderm, mesoderm and endoderm, from which all organ tissues are developed. During early embryonic development, mesodermal cells become sequentially determined to more precisely defined cell types including muscle, heart, vasculature, bl...

journal_title：Stem cell reviews and reports

authors： Doss MX,Gaspar JA,Winkler J,Hescheler J,Schulz H,Sachinidis A

更新日期：2012-03-01 00:00:00

abstract：:The model of cancer stem cells in tumor development states that tumors contain a subset of cells that both self renew and give rise to differentiated progeny. Like normal adult tissue stem cells, cancer stem cells are a minority of the whole tumor and are the only cells that are able to maintain tumor growth indefinit...

journal_title：Stem cell reviews and reports

authors： La Porta C

更新日期：2009-03-01 00:00:00

abstract：:There is a need for physiologically relevant assay platforms to provide functionally relevant models of diabetes, to accelerate the discovery of new treatment options and boost developments in drug discovery. In this review, we compare several 3D-strategies that have been used to increase the functional relevance of e...

journal_title：Stem cell reviews and reports

authors： Ribeiro D,Kvist AJ,Wittung-Stafshede P,Hicks R,Forslöw A

更新日期：2018-04-01 00:00:00

abstract：:The Networks of Centres of Excellence (NCE) is an innovative model of large-scale research networks that began in Canada in 1989, and has since been adopted by numerous countries around the globe. The Canadian Stem Cell Network (SCN), an NCE that has fostered stem cell research and innovation in Canada, has supported ...

journal_title：Stem cell reviews and reports

authors： Jacob KJ,Roskams-Edris D,Illes J

更新日期：2015-12-01 00:00:00

abstract：:Although bone marrow-derived mononuclear cells (BMNC) have been extensively used in cell therapy for cardiac diseases, little mechanistic information is available to support reports of their efficacy. To address this shortcoming, we compared structural and functional recovery and associated global gene expression prof...

journal_title：Stem cell reviews and reports

authors： Lachtermacher S,Esporcatte BL,Fortes Fda S,Rocha NN,Montalvão F,Costa PC,Belem L,Rabischoffisky A,Faria Neto HC,Vasconcellos R,Iacobas DA,Iacobas S,Spray DC,Thomas NM,Goldenberg RC,de Carvalho AC

更新日期：2012-03-01 00:00:00

abstract：:Although the stem cells are commonly isolated by FACS or MACS, they are very expensive and these is no specific marker for liver stem/progentior cells (LSPCs). This paper applied a convenient and efficient method to enrich LSPCs. The fetal liver cells (FLCs) were firstly enriched by Percoll discontinuous gradient cent...

journal_title：Stem cell reviews and reports

authors： Liu WH,Li R,Dou KF

更新日期：2011-03-01 00:00:00

abstract：:Chemotherapy constitutes one of the key treatment modalities for solid and hematological malignancies. Albeit being an effective treatment, chemotherapy application is often limited by its damage to healthy tissues, and curative treatment options for chemotherapy-related side effects are largely missing. As mesenchyma...

journal_title：Stem cell reviews and reports

authors： Rühle A,Lopez Perez R,Zou B,Grosu AL,Huber PE,Nicolay NH

更新日期：2019-06-01 00:00:00

abstract：:Reliable and efficient DNA and RNA transfection methods are required when studying the role of individual genes in mouse pluripotent stem cells. However, these cells usually grow in tight clusters and are therefore more difficult to transfect than many other cell lines. We have found that transfection is especially ch...

journal_title：Stem cell reviews and reports

authors： Tamm C,Kadekar S,Pijuan-Galitó S,Annerén C

更新日期：2016-10-01 00:00:00

abstract：:Surface topography of Titanium (Ti) dental implants strongly influences osseointegration. In the present work, we have analyzed the influence of two Ti implant surfaces characterized by similar microtopography but different nanotopography and chemistry on the osteoblastic phenotype of Dental Pulp Stem Cells (DPSCs). T...

journal_title：Stem cell reviews and reports

authors： Gardin C,Ferroni L,Piattelli A,SIvolella S,Zavan B,Mijiritsky E

更新日期：2016-10-01 00:00:00

abstract：:Mesenchymal stem cells (MSC) have been extensively studied over the past years for the treatment of different diseases. Most of the ongoing clinical trials currently involve the use of MSC derived from adult tissues. This source may have some limitations, particularly with therapies that may require extensive and repe...

journal_title：Stem cell reviews and reports

authors： Luzzani CD,Miriuka SG

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Bone marrow-derived mononuclear cells (BM-MNC) consist of a heterogeneous mix of mesenchymal stem cells (MSC), hematopoietic progenitor cells (HPC), endothelial progenitor cells (EPC), monocytes, lymphocytes and pluripotent stem cells. Whereas the importance of MSC and EPC has been well documented in bone he...

journal_title：Stem cell reviews and reports

authors： Leppik L,Sielatycka K,Henrich D,Han Z,Wang H,Eischen-Loges MJ,Oliveira KMC,Bhavsar MB,Ratajczak MZ,Barker JH

更新日期：2020-02-01 00:00:00

abstract：:Human embryonic stem cells (hESCs) are especially resistant to several cellular stresses, but the existence and induction of Endoplasmic Reticulum (ER) stress by culture conditions are unknown. Using qPCR, here, we investigated the behavior of the principal sensors of ER stress and their relation with the feeder layer...

journal_title：Stem cell reviews and reports

authors： Blanco-Gelaz MA,Suarez-Alvarez B,Ligero G,Sanchez L,Vidal-Castiñeira JR,Coto E,Moore H,Menendez P,Lopez-Larrea C

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Mesenchymal stem cells derived from the chorionic villi of human term placenta (pMSCs) have drawn considerable interest because of their multipotent differentiation potential and their immunomodulatory capacity. These properties are the foundation for their clinical application in the fields of stem cell tra...

journal_title：Stem cell reviews and reports

authors： Abomaray FM,Al Jumah MA,Kalionis B,AlAskar AS,Al Harthy S,Jawdat D,Al Khaldi A,Alkushi A,Knawy BA,Abumaree MH

更新日期：2015-06-01 00:00:00

abstract：:Multipotent mesenchymal stem/stromal cells (MSCs) have regenerative and immunomodulatory properties to restore and repair injured tissues, making them attractive candidates for cell-based therapies. Experimental and clinical evidence has demonstrated the effectiveness of MSC transplantation in managing diabetes mellit...

journal_title：Stem cell reviews and reports

authors： Mahmoud M,Abu-Shahba N,Azmy O,El-Badri N

更新日期：2019-04-01 00:00:00

abstract：:Mesenchymal stem cells (MSCs) represent a population of cells which have the ability to regulate reactivity of T and B lymphocytes by multiple mechanisms. The immunoregulatory activities of MSCs are strictly influenced by the cytokine environment. Here we show that two functionally distinct cytokines, interleukin-4 (I...

journal_title：Stem cell reviews and reports

authors： Holan V,Hermankova B,Bohacova P,Kossl J,Chudickova M,Hajkova M,Krulova M,Zajicova A,Javorkova E

更新日期：2016-12-01 00:00:00

abstract：:Here we present the principles and steps of a protocol that we have recently developed for the differentiation of hES/iPS cells into the authentic human striatal projection medium spiny neurons (MSNs) that die in Huntington's Disease (HD). Authenticity is judged by the convergence of multiple features within individua...

journal_title：Stem cell reviews and reports

authors： Delli Carri A,Onorati M,Castiglioni V,Faedo A,Camnasio S,Toselli M,Biella G,Cattaneo E

更新日期：2013-08-01 00:00:00

abstract：:Motor neuron loss or degeneration is the typical characteristic of amyotrophic lateral sclerosis (ALS), which often leads to weakness, paralysis, or even death. The underlying mechanisms of motor neuron degeneration and ALS progression remain elusive, and there is no effective treatment for ALS. The advances of stem c...

journal_title：Stem cell reviews and reports

authors： Zhao A,Pan Y,Cai S

更新日期：2020-06-01 00:00:00

abstract：:Chronic articular cartilage defects are the most common disabling conditions of humans in the western world. The incidence for cartilage defects is increasing with age and the most prominent risk factors are overweight and sports associated overloading. Damage of articular cartilage frequently leads to osteoarthritis ...

journal_title：Stem cell reviews and reports

authors： Preitschopf A,Zwickl H,Li K,Lubec G,Joo G,Rosner M,Hengstschläger M,Mikula M

更新日期：2012-12-01 00:00:00

abstract：INTRODUCTION:Whether transplanted cardiac stem cells (CSCs) and mesenchymal stem cells (MSCs) improved ventricular fibrillation threshold (VFT) similarly is still unclear. We sought to compare the effects of the CSC and MSC transplantation on the electrophysiological characteristics and VFT in rats with myocardial infa...

journal_title：Stem cell reviews and reports

authors： Zheng SX,Weng YL,Zhou CQ,Wen ZZ,Huang H,Wu W,Wang JF,Wang T

更新日期：2013-06-01 00:00:00

abstract：:Factors responsible for the rapid proliferative properties of embryonic stem (ES) cells are largely unknown. MicroRNA-221/222 (miR-221/222) regulate proliferation in many somatic cells, however, their roles in proliferation of ES cells are unclear. In this study, E14 mouse ES cells proliferation was determined by tota...

journal_title：Stem cell reviews and reports

authors： Li J,Bei Y,Liu Q,Lv D,Xu T,He Y,Chen P,Xiao J

更新日期：2015-02-01 00:00:00

abstract：:Metastasis is the worst prognosis predictor in the clinical course of cancer development. Features of metastatic cancer cells include migratory ability, low degree of differentiation, self-renewal and proliferation potentials, as well as resistance to therapies. Metastatic cells do not present all of the necessary cha...

journal_title：Stem cell reviews and reports

authors： Arnaud-Sampaio VF,Rabelo ILA,Ulrich H,Lameu C

更新日期：2020-04-01 00:00:00