Focal and diffuse liver disease studied by quantitative microstructural sonography.

Abstract:

:Quantitative microstructural sonography differs from conventional sonography in several ways. The frequency as well as the amplitude of echoes is recorded and assessed using spectral analysis techniques. The effects of diffraction of the ultrasound beam are calibrated, as are the transfer characteristics of the system. Studies of patients with alcoholic liver disease revealed significantly increased attenuation, heterogeneity of scatterers, and local scattering strength in those with severe disease; in contrast, patients with mild cirrhosis exhibited decreased local scattering strength compared to normal individuals. Using retrospective three-parameter discriminant analysis, 23 out of 24 patients were successfully categorized, suggesting that the parameters used were capable of measuring microstructural changes associated with these disease states. Parameters varied widely among 6 types of hepatic tumors, suggesting that this method may offer promise in distinguishing tumors from normal cases and alcoholic liver disease as well as from each other. Further applications and evaluation of this method appear justified.

journal_name

Radiology

journal_title

Radiology

authors

King DL,Lizzi FL,Feleppa EJ,Wai PM,Yaremko MM,Rorke MC,Herbst J

doi

10.1148/radiology.155.2.2984720

subject

Has Abstract

pub_date

1985-05-01 00:00:00

pages

457-62

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

155

pub_type

杂志文章
  • Cerebral perfusion CT: technique and clinical applications.

    abstract::Perfusion computed tomography (CT) is a relatively new technique that allows rapid qualitative and quantitative evaluation of cerebral perfusion by generating maps of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). The technique is based on the central volume principle (CBF = CBV/M...

    journal_title:Radiology

    pub_type: 杂志文章,评审

    doi:10.1148/radiol.2313021488

    authors: Hoeffner EG,Case I,Jain R,Gujar SK,Shah GV,Deveikis JP,Carlos RC,Thompson BG,Harrigan MR,Mukherji SK

    更新日期:2004-06-01 00:00:00

  • CT-pathologic correlations in Hodgkin's disease and non-Hodgkin's lymphoma.

    abstract::In order to assess its potential uses in the staging and treatment planning of lymphoma, CT was performed in 27 newly diagnosed, previously untreated patients with Hodgkin's disease or non-Hodgkin's lymphoma; 18 staging laparotomies provided pathologic correlations. CT detected and defined disease in areas not well ev...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/126.1.159

    authors: Breiman RS,Castellino RA,Harell GS,Marshall WH,Glatstein E,Kaplan HS

    更新日期:1978-01-01 00:00:00

  • A helpful technique for difficult urethral catheterizations in boys for voiding cystourethrography.

    abstract::A simple technique used to catheterize boys for voiding cystourethrography, using a feeding catheter while the urethra is distended by a saline solution is described. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.135.2.7367650

    authors: Lorenzo RL,Bradford BF

    更新日期:1980-05-01 00:00:00

  • Anatomic features of the carpal scaphoid: validation of biometric measurements and symmetry with three-dimensional MR imaging.

    abstract::The goals of reconstructive surgery for scaphoid fracture nonunions include restoration of normal scaphoid length and shape by use of the contralateral scaphoid bone as a geometric model. A literature search revealed limited documentation of normal biometric measurements and no validation of scaphoid anatomic symmetry...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.187.1.8451410

    authors: Smith DK

    更新日期:1993-04-01 00:00:00

  • False-Positive Measurement at 2-Hydroxyglutarate MR Spectroscopy in Isocitrate Dehydrogenase Wild-Type Glioblastoma: A Multifactorial Analysis.

    abstract::Background Isocitrate dehydrogenase (IDH) mutation has become one of the most important prognostic biomarkers in glioma management. Measurement of 2-hydroxyglutarate (2HG) with MR spectroscopy has shown high pooled sensitivity, although false-positive results with MR spectroscopy have been reported. Purpose To investi...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2019182200

    authors: Suh CH,Kim HS,Paik W,Choi C,Ryu KH,Kim D,Woo DC,Park JE,Jung SC,Choi CG,Kim SJ

    更新日期:2019-06-01 00:00:00

  • A new device for barium-enema examination following colostomy.

    abstract::The authors developed a colostomy appliance for use during barium-enema examinations. It is 8 cm in diameter and 4 cm in height, and is made of acrylic resins. With the use of this device, 21 patients were fluoroscopically examined through the stoma; good contrast views of the lower intestinal tract were obtained in a...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/133.1.241

    authors: Sarashina H,Ozaki A,Fukao K,Takase Y,Todoroki T,Nagoshi K,Ohshima M,Kawakita I,Iwasaki Y

    更新日期:1979-10-01 00:00:00

  • Noninvasive quantification of airway inflammation following segmental allergen challenge with functional MR imaging: a proof of concept study.

    abstract:PURPOSE:To evaluate oxygen-enhanced T1-mapping magnetic resonance (MR) imaging as a noninvasive method for visualization and quantification of regional inflammation after segmental allergen challenge in asthmatic patients compared with control subjects. MATERIALS AND METHODS:After institutional review board approval, ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.14132607

    authors: Renne J,Hinrichs J,Schönfeld C,Gutberlet M,Winkler C,Faulenbach C,Jakob P,Schaumann F,Krug N,Wacker F,Hohlfeld JM,Vogel-Claussen J

    更新日期:2015-01-01 00:00:00

  • Xeroradiography of the thyroid.

    abstract::In a study of 726 patients, xeroradiography of the thyroid using a modified oblique projection was found to be superior to conventional soft-tissue radiography in detecting calcification in thyroid tumors because of edge enhancement. This facilitated a diagnosis of carcinoma in 75% of 68 primary tumors and 55% of 33 r...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.141.2.7291570

    authors: Kasai N,Tsuya A

    更新日期:1981-11-01 00:00:00

  • Non-western patterns of biliary stones and the role of ascariasis.

    abstract::Biliary calculi of a non-Western pattern were detected in 15 patients on real-time sonography performed over a 3-year period in a center serving a predominantly "Cape colored" (mixed race) population in South Africa. In two patients definite calculi were detected only in the common bile duct or gallbladder, but there ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.162.2.3541030

    authors: Schulman A

    更新日期:1987-02-01 00:00:00

  • Traumatic atlanto-occipital dislocation in children.

    abstract::During a 5-year period, 11 children were identified as having traumatic atlanto-occipital dislocation injury on the basis of clinical and radiographic findings. Radiographic criteria including the distance between the tip of the dens and the basion (DB distance), the BC/OA ratio (ratio of the distance between the basi...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.188.1.8511290

    authors: Bulas DI,Fitz CR,Johnson DL

    更新日期:1993-07-01 00:00:00

  • MR colonography: development of optimized method with ex vivo and in vivo systems.

    abstract::An ex vivo magnetic resonance (MR) colonographic system with a bovine colon with polyps of predetermined dimensions was developed for evaluation and optimization of different combinations of imaging sequences and intraluminal contrast agents. Findings were then applied during in vivo testing in human subjects. The res...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2251011664

    authors: Martin DR,Yang M,Thomasson D,Acheson C

    更新日期:2002-11-01 00:00:00

  • Determining Malignant Potential of Intraductal Papillary Mucinous Neoplasm of the Pancreas: CT versus MRI by Using Revised 2017 International Consensus Guidelines.

    abstract::Background Several changes have been made to the revised 2017 international consensus guidelines for management of pancreatic intraductal papillary mucinous neoplasms (IPMNs). However, the diagnostic performance is yet to be verified. Purpose To evaluate the revised guidelines for predicting malignant potential of pan...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2019190144

    authors: Lee JE,Choi SY,Min JH,Yi BH,Lee MH,Kim SS,Hwang JA,Kim JH

    更新日期:2019-10-01 00:00:00

  • Vacuum phenomenon simulating meniscal or cartilaginous injury of the knee at MR imaging.

    abstract::In five patients undergoing magnetic resonance imaging of the knee after athletic injuries, the authors identified a vacuum phenomenon that simulated medial meniscal or joint compartment cartilaginous abnormality. A cadaveric knee was injected with air, and the findings were re-created. The presence of air or gas betw...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.180.2.2068320

    authors: Shogry ME,Pope TL Jr

    更新日期:1991-08-01 00:00:00

  • Ultrasound evaluation of the gallbladder wall.

    abstract::In a series of 526 consecutive, unprepared patients examined by ultrasound, the gallbladder was visualized in 507 (96%). The average wall thickness was 2 mm or less in 97% of asymptomatic subjects without cholelithiasis and 3 mm or greater in 45% of those with choletithiasis. Pathologic correlation of increased thickn...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/133.3.693

    authors: Finberg HJ,Birnholz JC

    更新日期:1979-12-01 00:00:00

  • Biphasic CT with mesenteric CT angiography in the evaluation of acute mesenteric ischemia: initial experience.

    abstract:PURPOSE:To evaluate the sensitivity and specificity of biphasic computed tomography (CT) with mesenteric CT angiography in the diagnosis of acute mesenteric ischemia (AMI). MATERIALS AND METHODS:Sixty-two patients with clinically suspected AMI underwent prospective imaging with biphasic multi-detector row CT. Mesenter...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2291020991

    authors: Kirkpatrick ID,Kroeker MA,Greenberg HM

    更新日期:2003-10-01 00:00:00

  • Superparamagnetic iron oxide-enhanced MR imaging: pulse sequence optimization for detection of liver cancer.

    abstract::The effects of magnetic resonance (MR) pulse sequences and timing parameters on tumor-liver contrast were studied in an animal model of metastatic liver cancer. Six spin-echo (SE), three inversion-recovery (IR), and four gradient-echo (GRE) sequences were evaluated at 0.6 T before and after injection of super-paramagn...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.172.2.2748820

    authors: Fretz CJ,Elizondo G,Weissleder R,Hahn PF,Stark DD,Ferrucci JT Jr

    更新日期:1989-08-01 00:00:00

  • Screening interval breast cancers: mammographic features and prognosis factors.

    abstract:PURPOSE:To review the mammographic features of screening interval breast cancers and to compare the tumor size, histologic grade, and lymph node involvement with those in screening-detected and unscreened symptomatic cancers. MATERIALS AND METHODS:Screening mammography was performed in 72,773 women aged 50-64 years. N...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.199.3.8638010

    authors: Burrell HC,Sibbering DM,Wilson AR,Pinder SE,Evans AJ,Yeoman LJ,Elston CW,Ellis IO,Blamey RW,Robertson JF

    更新日期:1996-06-01 00:00:00

  • A comparison of methods for assessing patient body burden following 131I therapy for thyroid cancer.

    abstract::The effectiveness of three methods of assessing the patient body burden following 131I therapy was compared: (a) urine assay, (b) external exposure rate measurements, and (c) predictions based on a pretherapy diagnostic work-up. The urine assay method exhibited the greatest potential for error and personnel risk. The ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.137.3.7444070

    authors: Thomas SR,Maxon HR,Fritz KM,Kereiakes JG,Connell WD

    更新日期:1980-12-01 00:00:00

  • Calcifications in breast biopsy specimens: discrepancies in radiologic-pathologic identification.

    abstract::To analyze the effectiveness and accuracy of the diagnostic process from screening mammography to final diagnosis at pathologic examination, the authors conducted a prospective study of 277 consecutive patients who underwent 291 mammographically directed biopsies of nonpalpable lesions. Of the 170 lesions that demonst...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.179.1.2006260

    authors: Stein MA,Karlan MS

    更新日期:1991-04-01 00:00:00

  • Coronary artery calcification detected with ultrafast CT as an indication of coronary artery disease.

    abstract::To assess the relationship of coronary artery calcification to angiographically detectable disease, the authors evaluated 100 patients less than 60 years of age who underwent clinically indicated coronary angiography and ultrafast computed tomography (CT). The ultrafast CT technique consisted of 3-mm-thick contiguous ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.185.2.1410350

    authors: Breen JF,Sheedy PF 2nd,Schwartz RS,Stanson AW,Kaufmann RB,Moll PP,Rumberger JA

    更新日期:1992-11-01 00:00:00

  • Hepatocellular carcinoma: MR imaging findings in cirrhotic livers and noncirrhotic livers.

    abstract:PURPOSE:To compare the magnetic resonance (MR) imaging findings of primary hepatocellular carcinoma (HCC) in cirrhotic versus noncirrhotic livers. MATERIALS AND METHODS:MR images in 36 patients with HCC (30 men and she women aged 42-84 years [mean age, 65 years]) were retrospectively reviewed. The number and size of h...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.210.1.r99ja1975

    authors: Winston CB,Schwartz LH,Fong Y,Blumgart LH,Panicek DM

    更新日期:1999-01-01 00:00:00

  • Computed tomography in congenital anomalies of the aortic arch and great vessels.

    abstract::Computed tomography can help in the evaluation of congenitally anomalous aortic arches and subclavian arteries. The authors discuss the role of computed tomography in the evaluation of such anomalies in seven patients. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.138.2.7455120

    authors: McLoughlin MJ,Weisbrod G,Wise DJ,Yeung HP

    更新日期:1981-02-01 00:00:00

  • Dermal calcifications in fixed orientation: the tattoo sign.

    abstract::Calcifications located in the dermis of the breast may appear indistinguishable from intramammary calcifications. The authors present a sign, called the tattoo sign, that can help radiologists identify dermal calcifications. When mammograms are compared, calcifications that maintain a fixed relationship to each other ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.192.1.8208930

    authors: Homer MJ,D'Orsi CJ,Sitzman SB

    更新日期:1994-07-01 00:00:00

  • Computer network security for the radiology enterprise.

    abstract::As computer networks become an integral part of the radiology practice, it is appropriate to raise concerns regarding their security. The purpose of this article is to present an overview of computer network security risks and preventive strategies as they pertain to the radiology enterprise. A number of technologies ...

    journal_title:Radiology

    pub_type: 杂志文章,评审

    doi:10.1148/radiology.220.2.r01au32303

    authors: Eng J

    更新日期:2001-08-01 00:00:00

  • Pachygyriclike changes: topographic appearance at MR imaging and CT and correlation with neurologic status.

    abstract::Studies of 23 pediatric patients with pachygyriclike changes (PLCs) examined with computed tomography (CT) and magnetic resonance (MR) imaging were reviewed to determine topographic patterns and correlate them with various clinical syndromes and degrees of neurologic impairment. Three types of topographic distribution...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.173.3.2554360

    authors: Titelbaum DS,Hayward JC,Zimmerman RA

    更新日期:1989-12-01 00:00:00

  • Benign hyperplastic nodules that originate in the peripheral zone of the prostate gland.

    abstract:PURPOSE:To describe a benign nodular lesion in the peripheral zone (PZ) of the prostate gland. MATERIALS AND METHODS:In 1,087 patients, the features of 722 focal lesions in the PZ or central zone of the prostate on transrectal ultrasound (TRUS) scans were retrospectively compared with histologic findings in biopsy sam...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.189.3.7694310

    authors: Oyen RH,Van de Voorde WM,Van Poppel HP,Brys PP,Ameye FE,Franssens YM,Baert AL,Baert LV

    更新日期:1993-12-01 00:00:00

  • Appraisal of the angiographic circulation time as an index of cerebral blood flow.

    abstract::The relationship of the brain angiographic mode circulation time (AVCT) to the mean transit time of the vascular indicator C15O-labeled hemoglobin (tc15o) and the regional cerebral blood flow (rCBF) as measured by the clearance of the diffusible tracer H2-15O was examined in 38 patients with selected cerebral diseases...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/115.1.107

    authors: Gado M,Eichling J,Grubb R,Phelps M,Raichie M,Ter-Pogossian MM

    更新日期:1975-04-01 00:00:00

  • Mediastinal lymphadenopathy and pulmonary arterial hypertension in mixed connective tissue disease.

    abstract::A case of mixed connective tissue disease (MCTD) is presented in which mediastinal lymphadenopathy was the most prominent radiological finding detected by plain chest radiographs and computed tomography. Pulmonary arterial hypertension, which is a rare and often fatal complication of MCTD, also developed in this patie...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.154.2.3155570

    authors: Guit GL,Shaw PC,Ehrlich J,Kroon HM,Oudkerk M

    更新日期:1985-02-01 00:00:00

  • Air trapping in heart-lung transplant recipients: variability of anatomic distribution and extent at sequential expiratory thin-section CT.

    abstract:PURPOSE:To evaluate the intrapatient reproducibility of the extent and anatomic distribution of air trapping at sequential expiratory thin-section computed tomographic (CT) examinations in heart-lung transplant recipients. MATERIALS AND METHODS:Nineteen heart-lung transplant recipients (eight with and 11 without bronc...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2293020827

    authors: Bankier AA,Van Muylem A,Scillia P,De Maertelaer V,Estenne M,Gevenois PA

    更新日期:2003-12-01 00:00:00

  • Invasive cervical carcinoma: role of MR imaging in pretreatment work-up--cost minimization and diagnostic efficacy analysis.

    abstract:PURPOSE:To examine the cost and efficacy of diagnostic work-up in patients with invasive cervical cancer. MATERIALS AND METHODS:In 246 patients with invasive cervical cancer, all diagnostic tests performed before treatment were recorded. Patients were divided into two groups: those who underwent magnetic resonance (MR...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.198.2.8596840

    authors: Hricak H,Powell CB,Yu KK,Washington E,Subak LL,Stern JL,Cisternas MG,Arenson RL

    更新日期:1996-02-01 00:00:00