Abstract:
:Noroviruses are rapidly evolving RNA viruses and are generally known as the main cause of viral gastroenteritis worldwide. Particle stability is of special interest as transmission occurs via the faecal-oral route and virions are able to persist in the environment. Studies on norovirus capsid assembly and disassembly rely mainly on norovirus-like particles. Notably, stability of several human, murine and bovine variants has been investigated revealing distinct patterns of stability and also distinct assembly mechanisms and intermediates. Gathering information on these differences and common features may deepen our understanding of norovirus emergence and can potentially be used to distinguish variants. However, more systematic studies and standardized approaches are required.
journal_name
Curr Opin Viroljournal_title
Current opinion in virologyauthors
Pogan R,Dülfer J,Uetrecht Cdoi
10.1016/j.coviro.2018.05.003subject
Has Abstractpub_date
2018-08-01 00:00:00pages
59-65eissn
1879-6257issn
1879-6265pii
S1879-6257(18)30007-5journal_volume
31pub_type
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journal_title:Current opinion in virology
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journal_title:Current opinion in virology
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journal_title:Current opinion in virology
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journal_title:Current opinion in virology
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
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journal_title:Current opinion in virology
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
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journal_title:Current opinion in virology
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2020.07.011
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2012.08.003
更新日期:2012-10-01 00:00:00
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2014.02.003
更新日期:2014-04-01 00:00:00
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2016.02.011
更新日期:2016-06-01 00:00:00
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2020.09.002
更新日期:2020-12-01 00:00:00
abstract::The rVSV-ZEBOV vaccine is currently the only Ebola vaccine with demonstrated clinical efficacy in a ring-vaccination clinical trial. It has been shown to be reactogenic but immunogenic and safe in several Phase I clinical studies. However, its mechanisms of protection are unknown and available immunogenicity data are ...
journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2017.03.008
更新日期:2017-04-01 00:00:00
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2014.07.005
更新日期:2014-10-01 00:00:00
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2015.08.001
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2015.06.008
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2015.04.006
更新日期:2015-06-01 00:00:00
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journal_title:Current opinion in virology
pub_type: 杂志文章
doi:10.1016/j.coviro.2012.01.004
更新日期:2012-06-01 00:00:00
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journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2011.10.010
更新日期:2011-12-01 00:00:00
abstract::Changes in host range are central to virus emergence. Host range, together with its evolution, is determined by virus intrinsic factors, such as genetic traits determining its fitness in different hosts. Experimental analyses have shown the relevance in host range evolution of across-host fitness trade-offs. Host rang...
journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2018.12.003
更新日期:2019-02-01 00:00:00
abstract::Rift Valley fever virus is a mosquito-borne pathogen of livestock and humans that causes widespread and devastating outbreaks of severe and often fatal disease throughout Africa and portions of the Arabian Peninsula. Outbreaks can involve tens to hundreds of thousands of human cases, and millions of livestock. The sev...
journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2012.02.017
更新日期:2012-06-01 00:00:00
abstract::Biological invasions occur when plants, animals, or microbes are introduced to a new geographic region, then spread and have negative consequences for the local ecosystem. Across both plant and animal hosts, viruses can play diverse roles in biological invasions. First, viruses can either decrease or increase the impa...
journal_title:Current opinion in virology
pub_type: 杂志文章
doi:10.1016/j.coviro.2011.05.018
更新日期:2011-07-01 00:00:00
abstract::Effective vaccines are the cornerstone of our defenses against acute influenza virus infections that result in ∼500 000 annual deaths worldwide. For decades, an on-going concerted effort has been to develop a universal influenza vaccine to combat the looming threat of potentially pandemic emerging and re-emerging infl...
journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2018.11.005
更新日期:2019-02-01 00:00:00
abstract::Dengue is a potentially fatal viral disease for which treatment is limited to supportive care, and prevention and control are based on mosquito vector control programs. It is the fastest growing arboviral infection and is currently endemic in more than 100 tropical and subtropical countries, placing over 40% of the wo...
journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2013.05.014
更新日期:2013-06-01 00:00:00
abstract::CD27 is a co-stimulatory immune-checkpoint receptor, constitutively expressed on a broad range of T-cells (αβ and γδ), NK-cells and B-cells. Ligation of CD27 with CD70 results in potent co-stimulatory effects. In mice, co-stimulation of CD8+ T-cells through CD27 promotes immune activation and enhances primary, seconda...
journal_title:Current opinion in virology
pub_type: 杂志文章,评审
doi:10.1016/j.coviro.2016.12.001
更新日期:2017-02-01 00:00:00
abstract::Type I interferons (IFN-I) were first described over 50 years ago as factors produced by cells that interfere with virus replication and promote an antiviral state. Innate and adaptive immune responses to viruses are also greatly influenced by IFN-I. In this article we discuss the diversity of cellular sources of IFN-...
journal_title:Current opinion in virology
pub_type: 杂志文章
doi:10.1016/j.coviro.2011.10.026
更新日期:2011-12-01 00:00:00