Simian virus 40 small-t antigen-induced theophylline resistance is not mediated by cyclic AMP.

abstract：:Simian immunodeficiency virus (SIV) and human immunodeficiency virus (HIV) infections lead to rapid depletion of CD4(+) T cells from gut-associated lymphoid tissue (GALT). Although the administration of antiretroviral therapy (ART) has been shown to increase CD4(+) T-cell levels in the peripheral blood in both SIV and...

journal_title：Journal of virology

authors： George MD,Reay E,Sankaran S,Dandekar S

更新日期：2005-03-01 00:00:00

abstract：:The influenza virus NS1 protein inhibits the nuclear export of a spliced viral mRNA, NS2 mRNA (F. V. Alonso-Caplen, M. E. Nemeroff, Y. Qiu, and R. M. Krug, Genes Dev. 6:255-267, 1992). To identify the sequence in NS2 mRNA that is recognized by the NS1 protein, we developed a gel shift assay for the formation of specif...

journal_title：Journal of virology

authors： Qiu Y,Krug RM

更新日期：1994-04-01 00:00:00

abstract：:The fundamental event in prion disease is thought to be the posttranslational conversion of the cellular prion protein (PrPC) into a pathogenic isoform (PrPSc). The occurrence of PrPC on the cell surface and PrPSc in amyloid plaques in situ or in aggregates following purification complicates the study of the molecular...

journal_title：Journal of virology

authors： Williamson RA,Peretz D,Pinilla C,Ball H,Bastidas RB,Rozenshteyn R,Houghten RA,Prusiner SB,Burton DR

更新日期：1998-11-01 00:00:00

abstract：:The E1A gene of highly oncogenic type 12 adenovirus (Ad12) possesses a segment unique to this serotype and comprising 60 base pairs contiguous with and separating conserved regions 2 and 3 in the gene. A similar but slightly longer segment is also present in the E1A gene of highly oncogenic simian adenovirus type 7 (D...

journal_title：Journal of virology

authors： Telling GC,Williams J

更新日期：1994-02-01 00:00:00

abstract：:Inhibition of hepatitis B virus (HBV) replication and viral clearance from an infected host requires both the innate and adaptive immune responses. Expression of interferon (IFN)-inducible proteasome catalytic and regulatory subunits correlates with the IFN-alpha/beta- and IFN-gamma-mediated noncytopathic inhibition o...

journal_title：Journal of virology

authors： Robek MD,Garcia ML,Boyd BS,Chisari FV

更新日期：2007-01-01 00:00:00

abstract：:The novel low-pathogenic avian influenza A H7N9 viruses (LPAI H7N9 viruses) have been a threat to public health since their emergence in 2013 because of the high rates of mortality and morbidity that they cause. Recently, highly pathogenic variants of these avian influenza A H7N9 viruses (HPAI H7N9 viruses) have emerg...

journal_title：Journal of virology

authors： Yang L,Zhu W,Li X,Chen M,Wu J,Yu P,Qi S,Huang Y,Shi W,Dong J,Zhao X,Huang W,Li Z,Zeng X,Bo H,Chen T,Chen W,Liu J,Zhang Y,Liang Z,Shi W,Shu Y,Wang D

更新日期：2017-11-14 00:00:00

abstract：:Most strains of human immunodeficiency virus type 1 (HIV-1) which have only been carried in vitro in peripheral blood mononuclear cells (primary isolates) can be neutralized by antibodies, but their sensitivity to neutralization varies considerably. To study the parameters that contribute to the differential neutraliz...

journal_title：Journal of virology

authors： Cecilia D,KewalRamani VN,O'Leary J,Volsky B,Nyambi P,Burda S,Xu S,Littman DR,Zolla-Pazner S

更新日期：1998-09-01 00:00:00

abstract：:The tempo and intensity of retroviral neuropathogenesis are dependent on the capacity of the virus to invade the central nervous system. For murine leukemia viruses, an important determinant of neuroinvasiveness is the virus-encoded protein glycosylated Gag, the function of which in the virus life cycle is not known. ...

journal_title：Journal of virology

authors： Fujisawa R,McAtee FJ,Wehrly K,Portis JL

更新日期：1998-07-01 00:00:00

abstract：:Poliovirus-specific RNA-dependent RNA polymerase (3Dpol) was purified to apparent homogeneity. A single polypeptide of an apparent molecular weight of 63,000 catalyzes the synthesis of dimeric and monomeric RNA products in response to the poliovirion RNA template. Analysis of purified 3Dpol by two-dimensional electrop...

journal_title：Journal of virology

authors： Ransone LJ,Dasgupta A

更新日期：1989-11-01 00:00:00

abstract：:Resistance to erythroleukemia induced by infection with the Friend virus complex (FV) has been mapped to several genes residing both within and outside the murine major histocompatibility complex (MHC). MHC genes located in the A, D, and Qa/Tla regions of the murine H-2 complex have been shown to affect disease resist...

journal_title：Journal of virology

authors： Perry LL,Miyazawa M,Hasenkrug K,Wehrly K,David CS,Chesebro B

更新日期：1994-08-01 00:00:00

abstract：:Ascoviruses (family Ascoviridae) are double-stranded DNA viruses with circular genomes that attack lepidopterans, where they produce large, enveloped virions, 150 by 400 nm, and cause a chronic, fatal disease with a cytopathology resembling that of apoptosis. After infection, host cell DNA is degraded, the nucleus fra...

journal_title：Journal of virology

authors： Bideshi DK,Demattei MV,Rouleux-Bonnin F,Stasiak K,Tan Y,Bigot S,Bigot Y,Federici BA

更新日期：2006-12-01 00:00:00

abstract：:Six overlapping viral RNAs are synthesized in cells infected with the avian coronavirus infectious bronchitis virus (IBV). These RNAs contain a 3'-coterminal nested sequence set and were assumed to be viral mRNAs. The seven major IBV virion proteins are all produced by processing of three polypeptides of ca. 23, 51, a...

journal_title：Journal of virology

authors： Stern DF,Sefton BM

更新日期：1984-04-01 00:00:00

abstract：:Plasmacytoid dendritic cells (pcDC) and myeloid dendritic cells (myDC) are shown to express CD4 and low levels of CCR5 and CXCR4, but only myDC express DC SIGN, a C-type lectin that binds human immunodeficiency virus but does not mediate virus entry. Both DC types were more susceptible to infection with a macrophage t...

journal_title：Journal of virology

authors： Patterson S,Rae A,Hockey N,Gilmour J,Gotch F

更新日期：2001-07-01 00:00:00

abstract：:Betanodaviruses, the causal agents of viral nervous necrosis in marine fish, have bipartite positive-sense RNAs as genomes. The larger genomic segment, RNA1 (3.1 kb), encodes an RNA-dependent RNA polymerase, and the smaller genomic segment, RNA2 (1.4 kb), codes for the coat protein. Betanodaviruses have marked host sp...

journal_title：Journal of virology

authors： Iwamoto T,Okinaka Y,Mise K,Mori K,Arimoto M,Okuno T,Nakai T

更新日期：2004-02-01 00:00:00

abstract：:Cytomegalovirus (CMV) disease after bone marrow (BM) transplantation is often associated with BM graft failure. There are two possible reasons for such a correlation. First, a poor hematopoietic reconstitution of unrelated etiology could promote the progression of CMV infection by the lack of immune control. Alternati...

journal_title：Journal of virology

authors： Steffens HP,Podlech J,Kurz S,Angele P,Dreis D,Reddehase MJ

更新日期：1998-06-01 00:00:00

abstract：:A gene encoding the large T antigen of polyomavirus was inserted into the baculovirus Autographa californica nuclear polyhedrosis virus so that gene expression was under the control of the strong, very late polyhedrin gene promoter. Significantly more large T antigen was produced in recombinant virus-infected insect c...

journal_title：Journal of virology

authors： Rice WC,Lorimer HE,Prives C,Miller LK

更新日期：1987-05-01 00:00:00

abstract：:In 2010 and 2011, several devastating Newcastle disease (ND) outbreaks occurred in China, affecting broilers, layers, and breeders. The CK-JSX1-201005 virus was isolated from broiler breeder flocks vaccinated with the classical ND virus (NDV) vaccine program, but laying rate decreased from 80% to 30 to 40% in the clin...

journal_title：Journal of virology

authors： Chen F,Liu J,Liu D,Yan Z,Ji J,Qin J,Li H,Ma J,Bi Y,Xie Q

更新日期：2012-11-01 00:00:00

abstract：:The unit-length genome of human herpesvirus 6 (HHV-6) consists of a single unique component (U) bounded by direct repeats DRL and DRR and forms head-to-tail concatemers during productive infection. cis-elements which mediate cleavage and packaging of progeny virions (a sequences) are found at the termini of all herpes...

journal_title：Journal of virology

authors： Thomson BJ,Dewhurst S,Gray D

更新日期：1994-05-01 00:00:00

abstract：:Glycosylated, membrane-associated E1 (58-kDa) and E2 (47- to 49-kDa) rubella virus proteins and unglycosylated nucleoprotein C (33 kDa), from separately expressed vaccinia virus recombinants, were injected into golden Syrian hamsters. Rubella virus E1 and E2 glycoproteins consistently induced an organ-specific autoimm...

journal_title：Journal of virology

authors： Yoon JW,Choi DS,Liang HC,Baek HS,Ko IY,Jun HS,Gillam S

更新日期：1992-02-01 00:00:00

abstract：:In all retroviruses analyzed to date (except for the spumaretroviruses), the Zn(2+)-coordinating residues of nucleocapsid (NC) perform or assist in crucial reactions necessary to complete the retrovirus life cycle. Six replication-defective mutations have been engineered in the two NC Zn(2+) fingers (ZFs) of simian im...

journal_title：Journal of virology

authors： Yovandich JL,Chertova EN,Kane BP,Gagliardi TD,Bess JW Jr,Sowder RC 2nd,Henderson LE,Gorelick RJ

更新日期：2001-01-01 00:00:00

abstract：:Most patients infected with hepatitis C virus (HCV) become chronic carriers. Viruses that efficiently establish persistent infections must have effective ways of evading host defenses. In the case of HCV, little is known about how chronic infections are established or maintained. Besides hepatocytes, several reports s...

journal_title：Journal of virology

authors： Bergqvist A,Rice CM

更新日期：2001-01-01 00:00:00

abstract：:Three of thirty-six monoclonal antibodies were found to cause irreversible inactivation of type 1 poliovirus at 39 degrees C but not at 37 degrees C. Neutralization at 37 degrees C depended on aggregation and was reversible by acid-induced deaggregation; at 39 degrees C, the virions (N antigenic, 160S) were disrupted ...

journal_title：Journal of virology

authors： Delaet I,Boeyé A

更新日期：1993-09-01 00:00:00

abstract：:The varicella-zoster virus major transactivator, IE62, contains a potent N-terminal acidic transcriptional activation domain (TAD). Our experiments revealed that the minimal IE62 TAD encompasses amino acids (aa) 19 to 67. We showed that the minimal TAD interacts with the human Mediator complex. Site-specific mutations...

journal_title：Journal of virology

authors： Yamamoto S,Eletsky A,Szyperski T,Hay J,Ruyechan WT

更新日期：2009-06-01 00:00:00

abstract：:Simian foamy virus (SFV) infection and the subsequent immune response are not well characterized. Blood plasma, saliva, and urine were obtained from four humans and nine chimpanzees persistently infected with chimpanzee-type SFV for an unknown length of time. SFV-specific immunoglobulin G (IgG) antibodies, but not IgA...

journal_title：Journal of virology

authors： Cummins JE Jr,Boneva RS,Switzer WM,Christensen LL,Sandstrom P,Heneine W,Chapman LE,Dezzutti CS

更新日期：2005-10-01 00:00:00

abstract：:The HIV-1 Rev response element (RRE) is a 351-base element in unspliced and partially spliced viral RNA; binding of the RRE by the viral Rev protein induces nuclear export of RRE-containing RNAs, as required for virus replication. It contains one long, imperfect double helix (domain I), one branched domain (domain II)...

journal_title：Journal of virology

authors： O'Carroll IP,Thappeta Y,Fan L,Ramirez-Valdez EA,Smith S,Wang YX,Rein A

更新日期：2017-10-13 00:00:00

abstract：UNLABELLED:To investigate the molecular mechanism(s) by which herpes simplex virus 1 (HSV-1) tegument protein UL51 promotes viral replication, we screened for viral proteins that interact with UL51 in infected cells. Affinity purification of tagged UL51 in HSV-1-infected Vero cells was coupled with immunoblotting of th...

journal_title：Journal of virology

authors： Oda S,Arii J,Koyanagi N,Kato A,Kawaguchi Y

更新日期：2016-09-12 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) particles typically contain small amounts of the surface envelope protein (SU), and this is widely believed to be due to shedding of SU from mature virions. We purified proteins from HIV-1 and SIV isolates using procedures which allow ...

journal_title：Journal of virology

authors： Chertova E,Bess JW Jr,Crise BJ,Sowder II RC,Schaden TM,Hilburn JM,Hoxie JA,Benveniste RE,Lifson JD,Henderson LE,Arthur LO

更新日期：2002-06-01 00:00:00

abstract：:The establishment of de novo-generated patterns of DNA methylation is characterized by the gradual spreading of DNA methylation (I. Kuhlmann and W. Doerfler, J. Virol. 47:631-636, 1983; M. Toth, U. Lichtenberg, and W. Doerfler, Proc. Natl. Acad. Sci. USA 86:3728-3732, 1989; M. Toth, U. Müller, and W. Doerfler J. Mol. ...

journal_title：Journal of virology

authors： Orend G,Kuhlmann I,Doerfler W

更新日期：1991-08-01 00:00:00

abstract：:A protein-protein interaction within the helicase domain of the Tobacco mosaic virus (TMV) 126- and 183-kDa replicase proteins was previously implicated in virus replication (S. Goregaoker, D. Lewandowski, and J. Culver, Virology 282:320-328, 2001). To further characterize the interaction, polypeptides covering the in...

journal_title：Journal of virology

authors： Goregaoker SP,Culver JN

更新日期：2003-03-01 00:00:00

abstract：:An immunochemical analysis of the hemagglutinin (VP4) of the simian rotavirus SA11 was performed to better understand the structure and function of this molecule. Following immunization of mice with double-shelled virus particles and VP4-enriched fractions from CsCl gradients, a battery of anti-SA11 hybridomas was gen...

journal_title：Journal of virology

authors： Burns JW,Greenberg HB,Shaw RD,Estes MK

更新日期：1988-06-01 00:00:00