Abstract:
BACKGROUND:UK veterans suffering from a psychological or psychiatric illness as a consequence of service in the Second World War were entitled to a war pension. Their case files, which include regular medical assessments, are a valuable resource to investigate the nature, distribution and duration of symptoms. METHODS:A standardised form was used to collect data from pension records of a random sample of 500 UK army veterans from the first presentation in the 1940s until 1980. Data were also gathered from 50 civilians and 54 emergency responders with a pension for post-traumatic illness following air-raids. RESULTS:The 10 most common symptoms reported by veterans were anxiety, depression, sleep problems, headache, irritability/anger, tremor/shaking, difficulty completing tasks, poor concentration, repeated fears and avoidance of social contact. Nine of the 10 were widely distributed across the veteran population when symptoms were ranked by the number of subjects who reported them. Nine symptoms persisted significantly longer in the veteran sample than in emergency responders. These included seven of the most common symptoms, together with two others: muscle pain and restlessness. The persistence of these symptoms in the veteran group suggests a post-traumatic illness linked to lengthy overseas service in combat units. CONCLUSIONS:The nature and duration of symptoms exhibited by veterans may be associated with their experience of heightened risks. Exposure to severe or prolonged trauma seems to be associated with chronic multi-symptom illness, symptoms of post-traumatic stress and somatic expressions of pain that may delay or complicate the recovery process.
journal_name
Psychol Medjournal_title
Psychological medicineauthors
Engelbrecht A,Burdett H,Silva MJ,Bhui K,Jones Edoi
10.1017/S0033291718001460subject
Has Abstractpub_date
2019-04-01 00:00:00pages
811-818issue
5eissn
0033-2917issn
1469-8978pii
S0033291718001460journal_volume
49pub_type
杂志文章abstract:BACKGROUND:Identifying prodromal features that predate the onset of bipolar disorder (BD) may enable the prevention of BD and aid early intervention. This review addresses two key questions: Is there a bipolar prodrome? And, if there is, what are its characteristic features? METHOD:A comprehensive search of databases ...
journal_title:Psychological medicine
pub_type: 杂志文章,评审
doi:10.1017/S0033291710001790
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The correlates of insight in early-onset psychosis have received little previous attention. METHOD:We studied clinical correlates of insight in a sample of 110 adolescent recent-onset psychosis patients (mean age 15.53 years; psychotic symptoms present for <6 months). Insight was measured with the Scale to ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708004868
更新日期:2009-09-01 00:00:00
abstract::Parental representation was assessed with the Parental Bonding Instrument (PBI) in 12 monozygotic (MZ) and 19 dizygotic (DZ) same-sexed twin pairs discordant for DSM-III-R schizophrenia. The schizophrenic twins reported less care and more overprotection from both parents than the non-schizophrenic co-twins. Multiple r...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700028439
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Depression is one of the most common and debilitating non-motor symptoms of Parkinson's disease (PD). The neurocognitive mechanisms underlying depression in PD are unclear and treatment is often suboptimal. METHODS:We investigated the role of striatal dopamine in reversal learning from reward and punishment...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291717000769
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:The outcome of schizophrenia appears to be more favourable than once thought. However, methodological issues, including the reliance on diagnosis at first presentation have limited the validity of outcome studies to date. METHOD:We conducted a first-episode follow-up study of 97 patients with DSM-IV schizop...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329170800336X
更新日期:2008-08-01 00:00:00
abstract::The concept of allusive thinking is briefly reviewed and a Pavlovian model of thinking advanced. It is hypothesized that allusive, as compared with non-allusive thinkers, have a broader but less intense attention process associated with weaker inhibition. From this model it was predicted that on word tests which requi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700004414
更新日期:1977-08-01 00:00:00
abstract:BACKGROUND:The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups ar...
journal_title:Psychological medicine
pub_type: 杂志文章,多中心研究
doi:10.1017/S0033291706008774
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Pregnant women require increased levels of n-3 polyunsaturated fatty acids (PUFAs) due to the demands of the growing fetus. Although some evidence indicates that maternal intake of fish and n-3 PUFAs is associated with reduced risk of postpartum depression, the results are inconsistent. METHODS:We investiga...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719002587
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Epidemiological evidence suggests a link between cannabis use and psychosis. A variety of factors have been proposed to mediate an individual's vulnerability to the harmful effects of the drug, one of which is their psychosis proneness. We hypothesized that highly psychosis-prone individuals would report mor...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291708004741
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Reward dysfunction is a major dimension of depressive symptomatology, but it remains obscure if that dysfunction varies across different reward types. In this study, we focus on the abnormalities in anticipatory/consummatory processing of monetary and social reward associated with depressive symptoms. METHO...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720003967
更新日期:2020-11-04 00:00:00
abstract::A cohort of 181 users of community psychiatric services in Camberwell with at least one year's history of contact was traced for two years following a census day. Four of the eight patients who had been given a primary diagnosis of an organic condition died during this period. For the others the population-standardize...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700051072
更新日期:1983-05-01 00:00:00
abstract::Preliminary data from the National Institute of Mental Health-Clinical Research Branch Collaborative Program on the Psychobiology of Depression dealing with the human growth hormone (hGH) response to the Insulin Tolerance Test (ITT) during the pre-treatment (drug-free) period of the study are presented in this paper. ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700043270
更新日期:1982-02-01 00:00:00
abstract:BACKGROUND:Social anxiety disorder (SAD) is surprisingly prevalent among people with psychosis and exerts significant impact on social disability. The processes that underlie its development remain unclear. The aim of this study was to investigate the relationship between shame cognitions arising from a stigmatizing ps...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712001146
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:This study aimed to determine whether depression in patients with long-term conditions is associated with the number of morbidities or the type of co-morbidity. Method A cohort study of 299 912 participants aged 30-100 years. The prevalence of depression, rates of health-care utilization and costs were evalu...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291712002498
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Quetiapine (ICI 204,636, 'Seroquel') is a new atypical antipsychotic agent with a similar binding profile to the original atypical antipsychotic, clozapine. Its clinical efficacy has already been demonstrated at multiple fixed doses (150-750 mg/day) and has been suggested to be comparable with haloperidol (1...
journal_title:Psychological medicine
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1017/s0033291799001476
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:It has been suggested that individual differences in temperament could be involved in the (non-)response to antidepressant (AD) treatment. However, how neurobiological processes such as brain glucose metabolism may relate to personality features in the treatment-resistant depressed (TRD) state remains largel...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291720005425
更新日期:2021-01-28 00:00:00
abstract:BACKGROUND:Item 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, most positive responses are not associated with suicidality. The PHQ-8, which omits Item 9, is thus increasingly used in research. We ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291719001314
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Empirical data regarding prevalence of sexual and physical abuse histories in Japanese patients with eating disorders is lacking, in contrast to Western countries. This study investigated the prevalence of traumatic events in Japanese patients with eating disorders, and examined the relationship between such...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291799008557
更新日期:1999-07-01 00:00:00
abstract::Brown and his colleagues have presented evidence for the social origins of depression from results of 2 community surveys in Camberwell. This paper examines critically their methodology, conceptualization of variables, mode of argument and statistical techniques. Log-linear analysis of their published data fails to su...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s003329170001878x
更新日期:1978-11-01 00:00:00
abstract::The Social Behaviour Schedule (SBS) was examined as a measure of disability in a series of 66 chronic psychiatric patients, who were also assessed using the Social Role Performance Schedule (SRP) and the ninth edition of the Present State Examination (PSE). All three schedules have been used in previous studies in the...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700025046
更新日期:1987-05-01 00:00:00
abstract:BACKGROUND:Little research has examined genetic and environmental contributions to psychopathic personality traits. Additionally, no studies have examined etiological connections between psychopathic traits and the broad psychopathological domains of internalizing (mood and anxiety) and externalizing (antisocial behavi...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291704004180
更新日期:2005-05-01 00:00:00
abstract:BACKGROUND:Based on the developing clinical and legal literature, and using the framework adopted in draft legislation, capacity to make a valid decision about a clinically required blood test was investigated in three groups of people with a 'mental disability' (i.e. mental illness (chronic schizophrenia), 'learning d...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700001768
更新日期:2000-03-01 00:00:00
abstract::The numbers of long-stay patients in Danish psychiatric hospitals were studied, based on information from the Danish cumulative psychiatric register and from the census studies of patients in Danish psychiatric hospitals, performed at 5-year intervals since 1957. In 1977, 2079 (20%) of the in-patient population which ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700032116
更新日期:1979-08-01 00:00:00
abstract::The Eating Attitudes Test (EAT) and General Health Questionnaire (GHQ) have been validated in an unselected population of 15-year-old South London schoolgirls. Scores on the questionnaires were compared with the results of standard interview. The EAT was found to be an efficient screening instrument for abnormal eatin...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700047991
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND:Several psychological and neurobiological models imply that patients with schizophrenia (SCZ) are more inclined to utilize emotional cues as response determinants to the detriment of more task-appropriate cognitive or contextual cues. However, there is a lack of behavioural data from human clinical studies t...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291713000445
更新日期:2013-11-01 00:00:00
abstract:BACKGROUND:Seeking compensation has been shown to have an adverse effect on the psychological health and recovery of injured patients, however, this effect requires clarification. METHODS:A total of 2019 adults sustaining a traffic injury were recruited. Of these, 709 (35.1%) lodged a compensation claim. Interviews oc...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S003329172000166X
更新日期:2020-06-09 00:00:00
abstract:BACKGROUND:Most evidence in the UK on the effectiveness of brief therapy for depression concerns cognitive behaviour therapy (CBT). In a trial published in 2000, we showed that non-directive counselling and CBT were equally effective in general practice for patients with depression and mixed anxiety and depression. Our...
journal_title:Psychological medicine
pub_type: 杂志文章,随机对照试验
doi:10.1017/S0033291713002377
更新日期:2014-07-01 00:00:00
abstract::Results are reported from a large population study (of working people) comparing Holocaust survivors and a control group in regard to emotional distress, satisfaction in life and psychosomatic symptoms. It was found that, even 40 years after the traumatic experience, this group of survivors exhibited a slightly higher...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/s0033291700002580
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:To assess the prevalence and clinical impact of co-morbid social anxiety disorder (SAD) and alcohol use disorders (AUD, i.e. alcohol abuse and alcohol dependence) in a nationally representative sample of adults in the United States. METHOD:Data came from a large representative sample of the US population. F...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291709991231
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Converging evidence implicates basal ganglia alterations in impulsivity and suicidal behavior. For example, D2/D3 agonists and subthalamic nucleus stimulation in Parkinson's disease (PD) trigger impulse control disorders and possibly suicidal behavior. Furthermore, suicidal behavior has been associated with ...
journal_title:Psychological medicine
pub_type: 杂志文章
doi:10.1017/S0033291711002133
更新日期:2012-06-01 00:00:00