Iterative Chemical Engineering of Vancomycin Leads to Novel Vancomycin Analogs With a High in Vitro Therapeutic Index.

abstract：:Milk spoilage is caused by the presence of proteolytic enzymes produced by Pseudomonas spp. during storage at low temperatures. The aim of this study was to identify Pseudomonas spp. in raw milk and investigate their associated proteolytic properties at low temperatures. Raw milk samples (n = 87) were collected from 8...

journal_title：Frontiers in microbiology

authors： Meng L,Zhang Y,Liu H,Zhao S,Wang J,Zheng N

更新日期：2017-11-08 00:00:00

abstract：:The effects of nodulation properties of legumes on the rhizosphere bacterial community are still not clear. To determine the effects of nodulation phenotypes on bacterial communities in the rhizosphere of soybean plants, we performed high-throughput sequencing of the 16S rRNA gene to estimate the rhizosphere bacterial...

journal_title：Frontiers in microbiology

authors： Wang H,Gu C,Liu X,Yang C,Li W,Wang S

更新日期：2020-05-12 00:00:00

abstract：:Acinetobacter baumannii is one of the most important nosocomial pathogens, and thus it is required to investigate how it disseminate in hospitals and infect patients. We performed whole genome sequencing for 24 A. baumannii strains isolated successively from the blood of a single patient to evaluate whether repeated i...

journal_title：Frontiers in microbiology

authors： Kim SJ,Kim YJ,Ko KS

更新日期：2018-11-27 00:00:00

abstract：:Low phosphorus soils are thought to constitute the majority of soils worldwide and cannot support intensive agriculture without high fertilizer inputs. Rhizobacteria are well-known to modify P dynamics and an increased bacterial diversity normally has a positive impact on various process rates. However, it is not know...

journal_title：Frontiers in microbiology

authors： Irshad U,Yergeau E

更新日期：2018-09-05 00:00:00

abstract：:Enterobacteria phage vB_PcaM_CBB is a "jumbo" phage belonging to the family Myoviridae. It possesses highly atypical whisker-like structures along the length of its contractile tail. It has a broad host range with the capability of infecting species of the genera Erwinia, Pectobacterium, and Cronobacter. With a genome...

journal_title：Frontiers in microbiology

authors： Buttimer C,Hendrix H,Oliveira H,Casey A,Neve H,McAuliffe O,Ross RP,Hill C,Noben JP,O'Mahony J,Lavigne R,Coffey A

更新日期：2017-01-24 00:00:00

abstract：:The gastrointestinal tract is an ideal habitat for diverse bacterial species that reside in a homeostatic balance with local tissue and significantly contribute to host health. Negative shifts in gut microbiota profiles, also known as dysbiosis, may be implicated in the development of chronic disorders such as inflamm...

journal_title：Frontiers in microbiology

authors： Babbar A,Hitch TCA,Pabst O,Clavel T,Hübel J,Eswaran S,Wagner N,Schippers A

更新日期：2019-10-04 00:00:00

abstract：:Mining industries produce vast waste streams that pose severe environmental pollution challenge. Conventional techniques of treatment are usually inefficient and unsustainable. Biological technique employing the use of microorganisms is a competitive alternative to treat mine wastes and recover toxic heavy metals. Mic...

journal_title：Frontiers in microbiology

authors： Ayangbenro AS,Olanrewaju OS,Babalola OO

更新日期：2018-08-22 00:00:00

abstract：:Bacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti-biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant strains. However, the...

journal_title：Frontiers in microbiology

authors： Fahim HA,Khairalla AS,El-Gendy AO

更新日期：2016-09-16 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) has been recognized to induce proinflammatory cytokine production and modulate the host interferon (IFN) system. Proinflammatory cytokines and type I IFNs contribute to the prevention of viral infection. Lipopolysaccharide (LPS), a specific agonist to Toll-li...

journal_title：Frontiers in microbiology

authors： Zhu Z,Zhang H,Zhang X,He S,Dong W,Wang X,Chen Y,Liu X,Guo C

更新日期：2020-03-25 00:00:00

abstract：:In Agrobacterium-mediated transformation (AMT) of plants, a single-strand (ss) T-DNA covalently linked with a VirD2 protein moves through a bacterial type IV secretion channel called VirB/D4. This transport system originates from conjugal plasmid transfer systems of bacteria. The relaxase VirD2 and its equivalent prot...

journal_title：Frontiers in microbiology

authors： Ohmine Y,Kiyokawa K,Yunoki K,Yamamoto S,Moriguchi K,Suzuki K

更新日期：2018-05-28 00:00:00

abstract：:The gastrointestinal microbiome is crucial in human health. With greater than 10 times the cell count of an individual, the gastrointestinal microbiome provides many benefits to the host. It plays an important role in chronic illnesses and immune diseases and also following burns and trauma. This study aimed to determ...

journal_title：Frontiers in microbiology

authors： Huang G,Sun K,Yin S,Jiang B,Chen Y,Gong Y,Chen Y,Yang Z,Chen J,Yuan Z,Peng Y

更新日期：2017-07-06 00:00:00

abstract：:The use of additives in food products has become an important public health concern. In recent reports, dietary emulsifiers have been shown to affect the gut microbiota, contributing to a pro-inflammatory phenotype and metabolic syndrome. So far, it is not yet known whether similar microbiome shifts are observable for...

journal_title：Frontiers in microbiology

authors： Miclotte L,De Paepe K,Rymenans L,Callewaert C,Raes J,Rajkovic A,Van Camp J,Van de Wiele T

更新日期：2020-11-05 00:00:00

abstract：:The genome sequences of several giant marine sulfur-oxidizing bacteria present evidence of a possible post-transcriptional regulatory network that may have been transmitted to or from two distantly related bacteria lineages. The draft genome of a Cand. "Maribeggiatoa" filament from the Guaymas Basin (Gulf of Californi...

journal_title：Frontiers in microbiology

authors： MacGregor BJ

更新日期：2015-12-16 00:00:00

abstract：:Phosphatidylglycerol (PG) is an indispensable phospholipid class with photosynthetic function in plants and cyanobacteria. However, its biosynthesis in eukaryotic green microalgae is poorly studied. Here, we report the isolation and characterization of two homologs (CrPGP1 and CrPGP2) of phosphatidylglycerophosphate s...

journal_title：Frontiers in microbiology

authors： Hung CH,Endo K,Kobayashi K,Nakamura Y,Wada H

更新日期：2015-08-24 00:00:00

abstract：:Toxoplasmosis, which is one of the most widespread zoonoses worldwide, has a high incidence and infection can result in severe disease in humans and livestock. Citrate synthase (CS) is a component of nearly all living cells that plays a vital role in the citric acid cycle, which is the central metabolic pathway of aer...

journal_title：Frontiers in microbiology

authors： Liu X,Ma Q,Sun X,Lu M,Ehsan M,Hasan MW,Xu L,Yan R,Song X,Li X

更新日期：2017-07-21 00:00:00

abstract：:Bacterial biofilms have an impact in medical and industrial environments because they often confer protection to bacteria against harmful agents, and constitute a source from which microorganisms can disperse. Conjugative plasmids can enhance bacterial ability to form biofilms because conjugative pili act as adhesion ...

journal_title：Frontiers in microbiology

authors： Gama JA,Fredheim EGA,Cléon F,Reis AM,Zilhão R,Dionisio F

更新日期：2020-08-26 00:00:00

abstract：:Staphylococci are a group of microorganisms that can be often found in processed food and they might pose a risk for human health. In this study we have determined the content of staphylococci in 7 different fresh goat-milk cheeses. These bacteria were present in all of them, ranging from 103 to 106 CFU/g based on gro...

journal_title：Frontiers in microbiology

authors： Perales-Adán J,Rubiño S,Martínez-Bueno M,Valdivia E,Montalbán-López M,Cebrián R,Maqueda M

更新日期：2018-06-12 00:00:00

abstract：:Escherichia coli O157: H7 (EHEC) is a major foodborne pathogen largely transmitted to humans through the consumption of undercooked ground beef. This study investigated the efficacy of two food-grade, plant-derived antimicrobials, namely rutin (RT), and resveratrol (RV) with or without chitosan (CH) in enhancing EHEC ...

journal_title：Frontiers in microbiology

authors： Surendran Nair M,Lau P,Belskie K,Fancher S,Chen CH,Karumathil DP,Yin HB,Liu Y,Ma F,Upadhyaya I,Upadhyay A,Mancini R,Venkitanarayanan K

更新日期：2016-02-02 00:00:00

abstract：:My effort to use synchronously dividing cultures to examine the Escherichia coli cell cycle involved a 10-year struggle with failure after failure punctuated by a few gratifying successes, especially at the end. In this essay, I recount my personal journey in this obsessive experimental pursuit. That narrative is foll...

journal_title：Frontiers in microbiology

authors： Helmstetter CE

更新日期：2015-03-25 00:00:00

abstract：:The rapid detection of foodborne microbial pathogens contaminating fresh fruits and vegetables during the intervening period between harvest and consumption could revolutionize microbial quality assurance of food usually consumed raw and those with a limited shelf life. We have developed a sensitive, shotgun whole gen...

journal_title：Frontiers in microbiology

authors： Ogunremi D,Dupras AA,Naushad S,Gao R,Duceppe MO,Omidi K,Márquez IG,Huang H,Goodridge L,Lévesque RC,Hasan NA,Dadlani M,Dixon B,Magierowski S,Masson L

更新日期：2020-04-17 00:00:00

abstract：:Targeting of the Gag polyprotein to the plasma membrane (PM) for assembly is a critical event in the late phase of immunodeficiency virus type-1 (HIV-1) infection. Gag binding to the PM is mediated by interactions between the myristoylated matrix (MA) domain and PM lipids. Despite the extensive biochemical and in vitr...

journal_title：Frontiers in microbiology

authors： Vlach J,Saad JS

更新日期：2015-03-20 00:00:00

abstract：:Coastal eutrophication is a key driver of shifts in bacterial communities on coral reefs. With fringing and patch reefs at varying distances from the coast the Spermonde Archipelago in southern Sulawesi, Indonesia offers ideal conditions to study the effects of coastal eutrophication along a spatially defined gradient...

journal_title：Frontiers in microbiology

authors： Kegler HF,Lukman M,Teichberg M,Plass-Johnson J,Hassenrück C,Wild C,Gärdes A

更新日期：2017-04-20 00:00:00

abstract：:Syngas generated by thermal gasification of biomass or coal can be steam reformed and purified into methane, which could be used locally for energy needs, or re-injected in the natural gas grid. As an alternative to chemical catalysis, the main components of the syngas (CO, CO2, and H2) can be used as substrates by a ...

journal_title：Frontiers in microbiology

authors： Sancho Navarro S,Cimpoia R,Bruant G,Guiot SR

更新日期：2016-08-03 00:00:00

abstract：:The estuarine nitrogen cycle can be substantially altered due to anthropogenic activities resulting in increased amounts of inorganic nitrogen (mainly nitrate). In the past, denitrification was considered to be the main ecosystem process removing reactive nitrogen from the estuarine ecosystem. However, recent reports ...

journal_title：Frontiers in microbiology

authors： Decleyre H,Heylen K,Van Colen C,Willems A

更新日期：2015-10-14 00:00:00

abstract：:Marine Group (MG) I (currently known as Thaumarchaeota) and MG II Archaea were first reported over two decades ago. While significant progress has been made on MG I microbiology and ecology, the progress on MG II has been noticeably slower. The common understanding is that while MG I mainly function as chemolithoautot...

journal_title：Frontiers in microbiology

authors： Zhang CL,Xie W,Martin-Cuadrado AB,Rodriguez-Valera F

更新日期：2015-10-13 00:00:00

abstract：:Because of the remarkable efficacy in treating mycobacterial infections, rifamycin and its derivatives are still first-line antimycobacterial drugs. It has been intensely studied to increase rifamycin yield from Amycolatopsis mediterranei, and nitrate is found to provide a stable and remarkable stimulating effect on t...

journal_title：Frontiers in microbiology

authors： Liu X,Liu Y,Lei C,Zhao G,Wang J

更新日期：2020-03-03 00:00:00

abstract：:Chlamydia suis is a swine pathogen that has also recently been found to cause zoonotic infections of the human eye, pharynx, and gastrointestinal tract. Many strains contain a tetracycline class C gene [tet(C)] cassette that confers tetracycline resistance. The cassette was likely originally acquired by horizontal gen...

journal_title：Frontiers in microbiology

authors： Marti H,Kim H,Joseph SJ,Dojiri S,Read TD,Dean D

更新日期：2017-02-07 00:00:00

abstract：:Wheat scab caused by F. graminearum is a highly destructive disease that leads to yield reduction and mycotoxin contamination of grains. In this study, an endophytic bacterium of strain YB-130 was isolated from surface sterilized wheat spikes with scab symptoms and identified as Bacillus velezensis by whole genome ann...

journal_title：Frontiers in microbiology

authors： Xu W,Zhang L,Goodwin PH,Xia M,Zhang J,Wang Q,Liang J,Sun R,Wu C,Yang L

更新日期：2020-12-03 00:00:00

abstract：:A variety of foods fermented with lactic acid bacteria serve as dietary staples in many African communities; yet, their bacterial profiles are poorly characterized. The integration of health-promoting probiotics into naturally fermented milk products could make a profound impact on human health. Here, we characterize ...

journal_title：Frontiers in microbiology

authors： Parker M,Zobrist S,Donahue C,Edick C,Mansen K,Hassan Zade Nadjari M,Heerikhuisen M,Sybesma W,Molenaar D,Diallo AM,Milani P,Kort R

更新日期：2018-09-21 00:00:00

abstract：:The effects of environmental and dispersal processes on macrofungi community assembly remain unclear. Further, it is not well understood if community assembly differs for different functional guilds of macrofungi, e.g., soil and rotten-wood macrofungi. In this study, using 2433 macrofungi sporocarps belonging to 217 s...

journal_title：Frontiers in microbiology

authors： Chen Y,Svenning JC,Wang X,Cao R,Yuan Z,Ye Y

更新日期：2018-01-23 00:00:00