Abstract:
Background:Overgrowth of candida results from factors that disrupt the intestinal microbial balance, such as the use of antibiotics. Unregulated antibiotic use and rampant practice of self-medication in Nigeria, is a cause for concern. Methods:A total of 314 stool specimens were collected from children <1 to 12 years of age in Nsukka, South Eastern Nigeria and screened for candida species using standard methods. Questionnaires were used to collect relevant information on the participants. Results:Out of the 314 participants, 31.2% had candidiasis, indicated by growth of ≥105 CFU/ml. Four different species of candida were identified. Candida albicans had the highest prevalence (59.0%), while Candida krusei had the least prevalence (6.0%). Of the 314 participants, 46.5% had diarrhoea, out of which 58.9% had intestinal candidiasis while only 14.3% of the non-diarrhoeic children had candidiasis. Of 208 participants who had taken antibiotics within three weeks of the study, 42.3% had candidiasis compared to 20.8% of those with no recent history of antibiotic use. Conclusion:The results of this study showed a high prevalence of intestinal candidiasis among children in Nsukka. Strong associations were observed between the presence of intestinal candidiasis and diarrhoea, age and use of antibiotics (p<0.001).
journal_name
Afr Health Scijournal_title
African health sciencesauthors
Ezeonu IM,Ntun NW,Ugwu KOdoi
10.4314/ahs.v17i4.27subject
Has Abstractpub_date
2017-12-01 00:00:00pages
1178-1184issue
4eissn
1680-6905issn
1729-0503pii
jAFHS.v17.i4.pg1178journal_volume
17pub_type
杂志文章abstract:BACKGROUND:Human Immunodeficiency virus (HIV) and Hepatitis C virus (HCV) are both major global health concerns as they cause high mortality and morbidity in the developing countries. However, while data exists for the co-infection in other countries, little or no information can be found with regard to the sero-preval...
journal_title:African health sciences
pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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journal_title:African health sciences
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