2,4-D poisoning: a review with illustration of two cases.

Abstract:

:2,4-D (2,4-dichlorphenoxyacetic acid) is a chlorphenoxy group pesticide. Its relative safety and broad leaf selectivity makes it a favourite herbicide of many home gardeners and agricultural workers. Severe systemic toxicity requiring hospital admission and intensive care usually occurs following intentional oral ingestion. 2,4-D poisoning is an under-recognised cause of a potentially lethal toxic syndrome, especially in low- and middle-income countries, where such compounds are widely used in farming and readily available in households. It warrants close monitoring and high-quality supportive care along with plasma alkalinisation or extracorporeal removal of the toxin.  We present a short review on 2,4-D poisoning and describe two illustrative cases with significant oral ingestion resulted in early and rapidly developing systemic toxicity. Both patients were admitted to the intensive care unit; one patient was managed with alkaline diuresis and other case required three sessions of haemodialysis.

journal_name

Trop Doct

journal_title

Tropical doctor

authors

Pannu AK,Saroch A,Agrawal J,Sharma N

doi

10.1177/0049475518786834

subject

Has Abstract

pub_date

2018-10-01 00:00:00

pages

366-368

issue

4

eissn

0049-4755

issn

1758-1133

journal_volume

48

pub_type

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