Abstract:
:Medications to treat children with rheumatic disease include disease-modifying antirheumatic drugs, glucocorticosteroids, and biologic response modifiers that target mediators and cells involved in autoimmunity and inflammation. Although usually well-tolerated, such medications have many possible side effects, of which primary care and emergency providers should be aware. Both disease and immunosuppression contribute to susceptibility to unusual and opportunistic infections, in addition to usual childhood infections for which these children should receive all applicable nonlive vaccines. Close coordination between the rheumatologist and other medical care providers is essential, because medication side effects, infections, and disease flares are difficult to distinguish, and may occur together.
journal_name
Pediatr Clin North Amjournal_title
Pediatric clinics of North Americaauthors
Higgins GCdoi
10.1016/j.pcl.2018.04.008subject
Has Abstractpub_date
2018-08-01 00:00:00pages
827-854issue
4eissn
0031-3955issn
1557-8240pii
S0031-3955(18)30047-6journal_volume
65pub_type
杂志文章,评审abstract::The safety of the blood supply has increased tremendously in the past decade. Donor screening and improved infectious disease testing of units for transfusion have contributed to the decreased risk of transfusion-transmitted diseases. Reduction of the number of passenger leukocytes from RBC and platelet transfusions d...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70433-8
更新日期:1996-06-01 00:00:00
abstract::College-age young women frequently experience a variety of menstrual-related complaints, including dysmenorrheal, menorrhagia, irregular menses, and menstrual-related mood changes. These problems deserve careful evaluation; they may reflect normal ovulatory menstrual symptoms or be suggestive of significant pathology ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2004.10.004
更新日期:2005-02-01 00:00:00
abstract::Endocrine disorders are common in infants in the neonatal ICU. They often are associated with prematurity, low birth weight or very low birth weight, and small size for gestational age. They also frequently occur in infants who are critically ill or stressed. This article describes the most common conditions and curre...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2011.07.003
更新日期:2011-10-01 00:00:00
abstract::Interprofessional collaborative practice (IPCP) is a service delivery approach that seeks to improve health care outcomes and the patient experience while simultaneously decreasing health care costs. The current article reviews the core competencies and current trends associated with IPCP, including challenges faced b...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2017.08.017
更新日期:2018-02-01 00:00:00
abstract::As new therapies for pediatric asthma are approved by the Food and Drug Administration, clinicians should be aware of their benefits and limitations. Accompanying these therapies are potential obstacles, including the delivery of inhaled therapies and age-specific issues regarding implementation and adherence. New ins...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2017.08.001
更新日期:2017-12-01 00:00:00
abstract::Evaluation of the newborn with hyperbilirubinemia is an important and commonly encountered problem in all clinical pediatric-based practices. Cholestatic jaundice is always pathologic and warrants prompt assessment. The timely evaluation and directed treatment of any jaundiced newborn are essential to prevent serious ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38655-2
更新日期:1993-12-01 00:00:00
abstract::Injuries to the pancreas and gastrointestinal tract following blunt abdominal trauma continue to be a significant cause of morbidity and mortality in the pediatric age group. Optimal treatment of these injuries is frequently hampered by considerable delays in diagnosis. Factors contributing to these delays include the...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)33136-4
更新日期:1975-05-01 00:00:00
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journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70445-4
更新日期:1996-08-01 00:00:00
abstract::Ocular trauma is a much more common cause of visual loss than is generally recognized. The authors present guidelines for the examination of eye injuries and follow with a discussion of the more common and more serious traumatic injuries. ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)34509-6
更新日期:1983-12-01 00:00:00
abstract::This article discusses the implications of health care reform on the pediatric emergency department (ED). The author briefly discusses the health care costs and outcomes in the United States in comparison to other developed nations. The article discusses the impact of the Affordable Care Act and insurance expansion on...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2018.07.007
更新日期:2018-12-01 00:00:00
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journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38877-0
更新日期:1994-12-01 00:00:00
abstract::This article outlines the use of alternative agents to TCAs and SSRIs. Features of the more commonly used alternative antidepressant agents are outlined. In addition, antidepressant agents that are currently either under development or used in other countries are indicated for completeness because it seems likely that...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70067-5
更新日期:1998-10-01 00:00:00
abstract::Trauma is prevalent in the lives of children. It derives from many sources, and, depending on its characteristics, can produce transient or enduring and devastating consequences. Early trauma, if left untreated, can set the stage for chronic deficits in the behavioral repertoires of affected children, and thus shape p...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(03)00075-0
更新日期:2003-08-01 00:00:00
abstract::Pediatric fractures are seen commonly in emergency departments. Pediatricians are usually the first physicians to assess injured children. Pediatricians should be comfortable in evaluating the fracture and interpreting radiographs prior to consulting an orthopedist. An understanding of the differences between pediatri...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70447-8
更新日期:1996-10-01 00:00:00
abstract::Duchenne muscular dystrophy is the second most common lethal genetic disorder in humans. With the advent of molecular genetic technology, the definition of this disease has been modified to include an abnormality of dystrophin in muscle--a dystrophinopathy. Accurate genetic counseling is possible using methods of dele...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38379-1
更新日期:1992-08-01 00:00:00
abstract::As a result of their preadoptive histories and experiences, internationally adopted children, especially those with a history of institutionalization, can present with a complex profile of developmental and behavioral issues. Although many children demonstrate significant recovery and resilience after joining their ad...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2005.06.010
更新日期:2005-10-01 00:00:00
abstract::The renin-angiotensin system plays multiple roles in the maintenance of normal blood pressure and renal function. The balance and integration of these roles change during development in ways that we do not yet fully understand. This article reviews the ways in which the renin-angiotensin system maintains normal cardio...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38481-4
更新日期:1993-02-01 00:00:00
abstract::Retinopathy of prematurity (ROP) remains a nonpreventable disorder associated with extreme prematurity. Recent advances in establishing the International Classification of ROP have facilitated both clinical care and research, highlighted by the demonstration of the effectiveness of cryoablative therapy for vision-thre...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)38581-9
更新日期:1993-08-01 00:00:00
abstract::Herpes simplex encephalitis (HSE) is an uncommon disease, yet 25 to 30 per cent of cases involve children. The initial clinical findings are nonspecific (fever, altered mental status), but most cases evolve to demonstrate focal neurologic signs and symptoms. The CSF is abnormal in over 90 per cent of cases. The EEG, C...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)36466-5
更新日期:1988-06-01 00:00:00
abstract::Disorders of sodium and water homeostasis are common occurrences in pediatric practice. They reflect distinct problems in the regulation of total body sodium balance and water distribution, respectively. Each of these groups of disorders has separate afferent and efferent mechanisms that are activated during disease s...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(16)40088-x
更新日期:1995-12-01 00:00:00
abstract::Radiologic studies are a vital component in the workup and diagnosis of disease. An appropriate radiographic study will accurately rule in or rule out disease with the least possible harm. Special considerations are necessary for the imaging of children. Current trends in pediatric imaging support the increased use of...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2013.06.004
更新日期:2013-10-01 00:00:00
abstract::Auricular reconstruction of microtia is available and is extremely satisfying for the patient, family, and care givers. The patient can look forward to a realistic pinna. With current research activity, auricular reconstruction could evolve even further. The pediatrician is an extremely important member of this effort...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0031-3955(05)70516-2
更新日期:1996-12-01 00:00:00
abstract::Early recognition and treatment of pediatric shock, regardless of cause, decreases mortality and improves outcome. In addition to the conventional parameters (eg, heart rate, systolic blood pressure, urine output, and central venous pressure), biomarkers and noninvasive methods of measuring cardiac output are availabl...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2013.02.013
更新日期:2013-06-01 00:00:00
abstract::The adoptive process can produce unusual stresses on the child, and biologic and adoptive parents, from prenatal to postnatal life, and through the various phases of physical and pscyhological development. Because of the possibility of these children and their families falling into the "at risk" category with greater ...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:
更新日期:1975-08-01 00:00:00
abstract::Doctors need to acquire telehealth consultation skills to thrive in the increasingly pressurized health system of delivering high-quality, high-volume health care with a shrinking health care workforce. Telehealth consultations require the same degree of thoroughness and careful clinical judgment as face-to-face consu...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
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更新日期:2020-08-01 00:00:00
abstract::Childhood lead poisoning is still an enormous public health issue in the United States, affecting thousands of children and their families. New evidence suggests that even very low blood lead levels, less than 10 microg/dL, can be associated with neurologic injury. This article discusses characteristics of children at...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2007.01.008
更新日期:2007-04-01 00:00:00
abstract::Outpatient encounters form the mainstay of managing type I diabetes mellitus in children and adolescents. Management philosophy rests on the premise that normal physical and emotional growth is attainable and long-term complications minimized by maintenance of metabolic (glycemic) control. Management principles involv...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
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journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2008.07.003
更新日期:2008-10-01 00:00:00
abstract::I have stressed the known medical and environmental factors associated with unexpected, sudden death in sports in children, and I have recommended restrictions or environmental alterations to prevent sudden death associated with an individual sport. Medical problems such as cardiomyopathies, posterior mitral valve lea...
journal_title:Pediatric clinics of North America
pub_type: 杂志文章
doi:10.1016/s0031-3955(16)34285-7
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abstract::The causes of macroscopic and microscopic hematuria overlap; both are often caused by urinary tract infections or urethral/bladder irritation. Coexistent hypertension and proteinuria should prompt investigation for glomerular disease. The most common glomerulonephritis in children is postinfectious glomerulonephritis....
journal_title:Pediatric clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.pcl.2018.08.003
更新日期:2019-02-01 00:00:00