Abstract：
:T follicular helper cells (TFH) are a subset of recently discovered CD4+ T cells. Their major function is to participate in the formation of germinal centres (GCs) and promote B cell proliferation and differentiation to play important roles in the production of antibodies. Currently, the functions of TFH cells are clear. However, the early differentiation of these cells is not clear. Dendritic cells (DCs) participate in the differentiation of TFH cells. Therefore, this article reviewed the research progress regarding the influence of DCs on the differentiation of TFH cells and their major underlying mechanisms.
journal_name
J Immunol Resjournal_title
Journal of immunology researchauthors
Zou X,Sun G,Huo F,Chang L,Yang Wdoi
10.1155/2018/7281453subject
Has Abstractpub_date
2018-07-02 00:00:00pages
7281453eissn
2314-8861issn
2314-7156journal_volume
2018pub_type
杂志文章,评审abstract：:Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that is characterized by synovial hyperplasia and progressive joint destruction. The activation of RA synovial fibroblasts (SFs), also called fibroblast-like synoviocytes (FLS), contributes significantly to perpetuation of the disease. Genetic and ...
journal_title：Journal of immunology research
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journal_title：Journal of immunology research
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更新日期：2017-01-01 00:00:00
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更新日期：2020-01-08 00:00:00
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更新日期：2016-01-01 00:00:00
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更新日期：2019-01-06 00:00:00
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pub_type： 杂志文章
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更新日期：2017-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2014-01-01 00:00:00
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