Effects of repetitive transcranial magnetic stimulation on cognitive function and cholinergic activity in the rat hippocampus after vascular dementia.

abstract：:The electrical excitability of neural networks is influenced by different environmental factors. Effective and simple methods are required to objectively and quantitatively evaluate the influence of such factors, including variations in temperature and pharmaceutical dosage. The aim of this paper was to introduce 'the...

journal_title：Neural regeneration research

authors： An S,Zhao YF,Lü XY,Wang ZG

更新日期：2018-06-01 00:00:00

abstract：:The cornea has unique features that make it a useful model for regenerative medicine studies. It is an avascular, transparent, densely innervated tissue and any pathological changes can be easily detected by slit lamp examination. Corneal sensitivity is provided by the ophthalmic branch of the trigeminal nerve that el...

journal_title：Neural regeneration research

authors： Sacchetti M,Lambiase A

更新日期：2017-08-01 00:00:00

abstract：:Generation of neurons in the brains of adult birds has been studied extensively in the telencephalon of song birds and few studies are reported on the distribution of PCNA and DCX in the telencephalon of adult non-song learning birds. We report here on adult neurogenesis throughout the brains of two breeds of adult do...

journal_title：Neural regeneration research

authors： Mazengenya P,Bhagwandin A,Nkomozepi P,Manger PR,Ihunwo AO

更新日期：2017-07-01 00:00:00

abstract：:The baker's yeast Saccharomyces (S.) cerevisiae is a single-celled eukaryotic model organism widely used in research on life sciences. Being a unicellular organism, S. cerevisiae has some evident limitations in application to neuroscience. However, yeast prions are extensively studied and they are known to share some ...

journal_title：Neural regeneration research

authors： Ishikawa T

更新日期：2021-03-01 00:00:00

abstract：:Alzheimer's disease is the leading cause of dementia. Its increased prevalence in developed countries, due to the sharp rise in ageing populations, presents one of the costliest challenges to modern medicine. In order to find disease-modifying therapies to confront this challenge, a more complete understanding of the ...

journal_title：Neural regeneration research

authors： Gray SC,Kinghorn KJ,Woodling NS

更新日期：2020-07-01 00:00:00

abstract：:Previous studies demonstrate an accumulation of transferrin and transferrin receptor 1 (TfR1) in regenerating peripheral nerves. However, the expression and function of transferrin and TfR1 in the denervated skeletal muscle remain poorly understood. In this study, a mouse model of denervation was produced by complete ...

journal_title：Neural regeneration research

authors： Li Y,Cheng JX,Yang HH,Chen LP,Liu FJ,Wu Y,Fan M,Wu HT

更新日期：2021-07-01 00:00:00

abstract：:Fimbria-fornix transection induces both exogenous and endogenous neural stem cells to differentiate into neurons in the hippocampus. This indicates that the denervated hippocampus provides an environment for neuronal differentiation of neural stem cells. However, the pathways and mechanisms in this process are still u...

journal_title：Neural regeneration research

authors： Zhang L,Han X,Cheng X,Tan XF,Zhao HY,Zhang XH

更新日期：2016-04-01 00:00:00

abstract：:Lentivirus carrying the Atoh1 gene can infect Corti's organ and express a hair-like cell surface marker in the supporting cell area. However, expression of the gene carried by adenovirus is instantaneous, which undoubtedly limits its clinical application. Lentivirus acts as a carrier that can stably and continuously e...

journal_title：Neural regeneration research

authors： Pan S,Wan J,Liu S,Zhang S,Xiong H,Zhou J,Xiong W,Yu K,Fu Y

更新日期：2013-06-15 00:00:00

abstract：:Gelatinases matrix metalloproteinase-2 and matrix metalloproteinase-9 have been shown to mediate claudin-5 and occludin degradation, and play an important regulatory role in blood-brain barrier permeability. This study established a rat model of 1.5-hour middle cerebral artery occlusion with reperfusion. Protein expre...

journal_title：Neural regeneration research

authors： Xin H,Liang W,Mang J,Lin L,Guo N,Zhang F,Xu Z

更新日期：2012-11-05 00:00:00

abstract：:Central nervous system injury, specifically traumatic brain and spinal cord injury, can have significant long lasting effects. There are no comprehensive treatments to combat the injury and sequalae of events that occurring following a central nervous system trauma. Herein we discuss the potential for the epothilone f...

journal_title：Neural regeneration research

authors： Clark J,Zhu Z,Chuckowree J,Dickson T,Blizzard C

更新日期：2021-04-01 00:00:00

abstract：:Although Parkinson's disease is the most common neurodegenerative movement disorder, the mechanisms of pathogenesis remain poorly understood. Recent findings have shown that deregulation of the autophagy-lysosome pathway is involved in the pathogenesis of Parkinson's disease. This review summarizes the most recent fin...

journal_title：Neural regeneration research

authors： Zhang L,Dong Y,Xu X,Xu Z

更新日期：2012-01-15 00:00:00

abstract：:The sciatic functional index (SFI) is a popular parameter for peripheral nerve evaluation that relies on footprints obtained with ink and paper. Drawbacks include smearing artefacts and a lack of dynamic information during measurement. Modern applications use digitized systems that can deliver results with less analyt...

journal_title：Neural regeneration research

authors： Fricker L,Penna V,Lampert F,Stark GB,Witzel C,Koulaxouzidis G

更新日期：2016-05-01 00:00:00

abstract：:The study illustrates that graphene oxide nanosheets can endow materials with continuous electrical conductivity for up to 4 weeks. Conductive nerve scaffolds can bridge a sciatic nerve injury and guide the growth of neurons; however, whether the scaffolds can be used for the repair of spinal cord nerve injuries remai...

journal_title：Neural regeneration research

authors： Yang B,Wang PB,Mu N,Ma K,Wang S,Yang CY,Huang ZB,Lai Y,Feng H,Yin GF,Chen TN,Hu CS

更新日期：2021-09-01 00:00:00

abstract：:Ototoxic drugs can be used to produce a loss of cochlear hair cells to create animal models of deafness. However, to the best of our knowledge, there is no report on the establishment of a rat deafness model through the combined application of aminoglycosides and loop diuretics. The aim of this study was to use single...

journal_title：Neural regeneration research

authors： Ma L,Yi HJ,Yuan FQ,Guo WW,Yang SM

更新日期：2015-10-01 00:00:00

abstract：:The location of an acute ischemic stroke is associated with its prognosis. The widely used Gaussian model-based parameter, apparent diffusion coefficient (ADC), cannot reveal microstructural changes in different locations or the degree of infarction. This prospective observational study was reviewed and approved by th...

journal_title：Neural regeneration research

authors： Zhu LH,Zhang ZP,Wang FN,Cheng QH,Guo G

更新日期：2019-02-01 00:00:00

abstract：:In this study, recombinant baculovirus carrying the microdystrophin and β-catenin genes was used to infect adipose-derived stem cells from a dystrophin-utrophin double knock-out mouse. Results showed that, after baculovirus transgene infection, microdystrophin and β-catenin genes were effectively expressed in adipose-...

journal_title：Neural regeneration research

authors： Li Q,Zhai Q,Geng J,Zheng H,Chen F,Kong J,Zhang C

更新日期：2012-08-05 00:00:00

abstract：:Three-dimensional (3D) histology utilizes tissue clearing techniques to turn intact tissues transparent, allowing rapid interrogation of tissue architecture in three dimensions. In this article, we summarized the available tissue clearing methods and classified them according to their physicochemical principles of ope...

journal_title：Neural regeneration research

authors： Lai HM,Ng HM,Wu W

更新日期：2017-01-01 00:00:00

abstract：:Glaucoma has been recently characterized as a member of the group of anoikis-related diseases. Anoikis, a form of apoptosis, can be triggered by the unfastening of adherent junctions present in astrocytes. In those areas of the central nervous system in which the soma of the neurons or their axons and dendrites are me...

journal_title：Neural regeneration research

authors： Carreras FJ

更新日期：2019-06-01 00:00:00

abstract：:The intrinsic growth ability of all the neurons declines during development although some may grow better than others. Numerous intracellular signaling proteins and transcription factors have been shown to regulate the intrinsic growth capacity in mature neurons. Among them, PI3 kinase/Akt pathway is important for con...

journal_title：Neural regeneration research

authors： Ohtake Y,Hayat U,Li S

更新日期：2015-09-01 00:00:00

abstract：:The quest for neuroprotective drugs to slow the progression of neurodegenerative diseases (NDDs), including Alzheimer's disease (AD), Parkinson's disease (PD), and Huntington's disease (HD), has been largely unrewarding. Preclinical evidence suggests that repurposing quetiapine, lithium, valproate, fluoxetine, donepez...

journal_title：Neural regeneration research

authors： Lauterbach EC

更新日期：2016-11-01 00:00:00

abstract：:In the present study, we examined the analgesic effect of repeated electroacupuncture at bilateral Zusanli (ST36) and Yanglingquan (GB34) once a day for 14 consecutive days in a rat model of chronic sciatic nerve constriction injury-induced neuropathic pain. In addition, concomitant changes in calcium/calmodulin-depen...

journal_title：Neural regeneration research

authors： Xu Q,Liu T,Chen S,Gao Y,Wang J,Qiao L,Liu J

更新日期：2012-06-25 00:00:00

abstract：:Spinal cord injury (SCI) is a devastating type of neurological trauma with limited therapeutic opportunities. The pathophysiology of SCI involves primary and secondary mechanisms of injury. Among all the secondary injury mechanisms, the inflammatory response is the major contributor and results in expansion of the les...

journal_title：Neural regeneration research

authors： Zhou X,He X,Ren Y

更新日期：2014-10-15 00:00:00

abstract：:Various studies have reported that galanin can promote axonal regeneration of dorsal root ganglion neurons in vitro and inhibit neuropathic pain. However, little is known about its effects on diabetic peripheral neuropathy, and in vivo experimental data are lacking. We hypothesized that repeated applications of exogen...

journal_title：Neural regeneration research

authors： Xu XF,Zhang DD,Liao JC,Xiao L,Wang Q,Qiu W

更新日期：2016-09-01 00:00:00

abstract：:One of the most important causes of brain injury in the neonatal period is a perinatal hypoxic-ischemic event. This devastating condition can lead to long-term neurological deficits or even death. After hypoxic-ischemic brain injury, a variety of specific cellular mechanisms are set in motion, triggering cell damage a...

journal_title：Neural regeneration research

authors： Lara-Celador I,Goñi-de-Cerio F,Alvarez A,Hilario E

更新日期：2013-03-15 00:00:00

abstract：:At 8 weeks after intragastric administration of icariin to senescence-accelerated mice (P8 strain), Morris water maze results showed that escape latency was shortened, and the number of platform crossings was increased. Immunohistochemical staining and western blot assay detected significantly increased levels of cycl...

journal_title：Neural regeneration research

authors： Zhang Z,Zhang T,Dong K

更新日期：2012-04-25 00:00:00

abstract：:The present study aimed to explore the mechanism underlying the protective effects of hydrogen sulfide against neuronal damage caused by cerebral ischemia/reperfusion. We established the middle cerebral artery occlusion model in rats via the suture method. Ten minutes after middle cerebral artery occlusion, the animal...

journal_title：Neural regeneration research

authors： Li XJ,Li CK,Wei LY,Lu N,Wang GH,Zhao HG,Li DL

更新日期：2015-06-01 00:00:00

abstract：:The structural plasticity of synaptic terminals contributes to normal nervous system function but also to neural degeneration, in the form of terminal retraction, and regeneration, due to process growth. Synaptic morphological change is mediated through the actin cytoskeleton, which is enriched in axonal and dendritic...

journal_title：Neural regeneration research

authors： Wang W,Townes-Anderson E

更新日期：2016-07-01 00:00:00

abstract：:A model of cerebral ischemia and reperfusion was established in mice. Mice were treated with ketamine via intraperitoneal injection immediately following ischemia or ischemia/reperfusion. Ketamine did not remarkably change infarct volume in mice immediately following ischemia, but injection immediately following ische...

journal_title：Neural regeneration research

authors： Xiao F,Xiong L,Wang Q,Zhou L,Zhou Q

更新日期：2012-04-15 00:00:00

abstract：:The influence of duration of immobilization and postoperative sensory re-education on the final outcome after reconstruction of digital nerves with direct suture or muscle-in-vein conduits was investigated. The final sensory outcome of 35 patients with 41 digital nerve injuries, who either underwent a direct suture (D...

journal_title：Neural regeneration research

authors： Manoli T,Schiefer JL,Schulz L,Fuchsberger T,Schaller HE

更新日期：2016-02-01 00:00:00

abstract：:The accumulation of myelin debris may be a major contributor to the inflammatory response after diffuse axonal injury. In this study, we examined the accumulation and clearance of myelin debris in a rat model of diffuse axonal injury. Oil Red O staining was performed on sections from the cerebral cortex, hippocampus a...

journal_title：Neural regeneration research

authors： Wen L,Xu J,Zhan T,Wang H,Huang X,Liu W,Yang X,Zhan R

更新日期：2014-11-01 00:00:00