Abstract：
:A new sildenafil analog has been identified in the softgel shell of a dietary supplement. The compound was investigated by UV spectroscopy and high-resolution MS analysis, leading to the proposed structure 1-methyl-5-{5-[2-(4-methylpiperazin-1-yl)acetyl]-2-propoxyphenyl}-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one. A synthetic reference compound with the proposed structure was prepared, and the two sets of analytical data were compared, confirming the structure of the new compound. The compound was named propoxyphenyl noracetildenafil from its structure and similarity with the known compound.
journal_name
J Pharm Biomed Analjournal_title
Journal of pharmaceutical and biomedical analysisauthors
Doi T,Takahashi K,Yamazaki M,Asada A,Takeda A,Kiyota K,Tagami T,Sawabe Y,Yamano Tdoi
10.1016/j.jpba.2018.08.031subject
Has Abstractpub_date
2018-11-30 00:00:00pages
61-65eissn
0731-7085issn
1873-264Xpii
S0731-7085(18)31276-7journal_volume
161pub_type
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