Inhibition of superoxide generation by human polymorphonuclear leukocytes with chlorhexidine. Its possible relation to periodontal disease.

Abstract:

:During the acute phase of periodontal disease, as many as 60% of the cells of the junctional epithelium may be accounted for by polymorphonuclear cells (PMNs). It is generally accepted that these cells play a dominant role in the destruction of connective tissue by virtue of the proteinases they release and the free oxygen radicals they generate. Modulation of the proteolytic activity and free radical production seems to be essential for the inhibition of tissue destruction. We have therefore studied the effect of chlorhexidine on the generation of free oxygen radicals and luminol-dependent chemiluminescence (LDCL) by stimulated human PMNs. Nontoxic chlorhexidine concentrations (0.1-1 microgram/ml) were found to inhibit superoxide production but did not affect LDCL. We therefore suggest that in addition to its antiseptic effect, chlorhexidine may also modulate the generation of free radicals by activated PMN cells in the inflamed gingiva.

journal_name

J Periodontol

authors

Goultschin J,Levy H

doi

10.1902/jop.1986.57.7.422

subject

Has Abstract

pub_date

1986-07-01 00:00:00

pages

422-5

issue

7

eissn

0022-3492

issn

1943-3670

journal_volume

57

pub_type

杂志文章
  • Enhancing effects of areca nut extracts on the production of interleukin-6 and interleukin-8 by peripheral blood mononuclear cells.

    abstract:BACKGROUND:The habit of chewing areca quid (AQ) has been implicated in oral pathogenesis, including periodontal disease. Little is understood about the roles of AQ in the cytokine secretion by immune cells. The study examined the effects of areca nut, the major ingredient of AQ, on the production of interleukin (IL)-6 ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2006.060039

    authors: Chang LY,Wan HC,Lai YL,Liu TY,Hung SL

    更新日期:2006-12-01 00:00:00

  • Clinical and histologic aspects of dental implants removed due to mobility.

    abstract:BACKGROUND:Implant failures are rare but do occur. Mechanical factors are certainly important in implant failures; so are biologic, iatrogenic, and functional factors. Mobility is the cardinal sign of implant failure. Three major etiologic factors have been suggested for implant failures: infection, impaired healing, a...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2003.74.3.385

    authors: Piattelli A,Scarano A,Favero L,Iezzi G,Petrone G,Favero GA

    更新日期:2003-03-01 00:00:00

  • Clinical oral medicine. An exciting facet of postdoctoral periodontic training.

    abstract::This paper briefly reviews the historical relationship between oral medicine and periodontics. The reasons for including structured clinical oral medicine in a postdoctoral program in periodontics are discussed. Problems and solutions to such an integrated program are outlined. Guidelines for broadening the base of th...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.7.426

    authors: Hurt WC

    更新日期:1986-07-01 00:00:00

  • The effects of a calorie-reduced diet on periodontal inflammation and disease in a non-human primate model.

    abstract:BACKGROUND:Low-calorie diets are commonplace for reducing body weight. However, no information is available on the effects of a reduced-calorie diet on periodontal inflammation and disease. The purpose of this study was to evaluate the clinical effects of a long-term calorie-restriction (CR) diet on periodontitis in an...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2008.070629

    authors: Branch-Mays GL,Dawson DR,Gunsolley JC,Reynolds MA,Ebersole JL,Novak KF,Mattison JA,Ingram DK,Novak MJ

    更新日期:2008-07-01 00:00:00

  • Alveolar ridge and sinus augmentation utilizing platelet-rich plasma in combination with freeze-dried bone allograft: case series.

    abstract:BACKGROUND:Alveolar bone regeneration is frequently necessary prior to placement of implants. Efforts to improve wound healing have focused on factors that may enhance bone formation following guided bone regeneration (GBR) techniques alone or in combination with bone replacement graft materials. Recent reports suggest...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2000.71.10.1654

    authors: Kassolis JD,Rosen PS,Reynolds MA

    更新日期:2000-10-01 00:00:00

  • Peri-implant soft tissue phenotype modification and its impact on peri-implant health: A systematic review and network meta-analysis.

    abstract:BACKGROUND:The peri-implant soft tissue phenotype (PSP) encompasses the keratinized mucosa width (KMW), mucosal thickness (MT), and supracrestal tissue height (STH). Numerous approaches to augment soft tissue volume around endosseous dental implants have been investigated. To what extent PSP modification is beneficial ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1002/JPER.19-0716

    authors: Tavelli L,Barootchi S,Avila-Ortiz G,Urban IA,Giannobile WV,Wang HL

    更新日期:2021-01-01 00:00:00

  • Osteogenic effects of bioabsorbable magnesium implant in rat mandibles and in vitro.

    abstract:BACKGROUND:Bone augmentation or grafting is often required for placement of dental implants or surgical reconstruction of bony defects. Bioabsorbable magnesium implant was shown to promote osteogenesis in long bones. The objectives of this study were to determine osteogenic effects of pure magnesium (Mg) in rat mandibl...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.20-0162

    authors: He W,Zhang H,Qiu J

    更新日期:2020-08-26 00:00:00

  • Vertical distance from the crest of bone to the height of the interproximal papilla between adjacent implants.

    abstract:BACKGROUND:As patient demand increases for more natural restorations in the esthetic zone, clinicians must have the highest level of skill and knowledge to maintain or reform the interdental papilla between teeth, between implants and teeth, and between adjacent implants. To date, there are no reports that have measure...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2003.74.12.1785

    authors: Tarnow D,Elian N,Fletcher P,Froum S,Magner A,Cho SC,Salama M,Salama H,Garber DA

    更新日期:2003-12-01 00:00:00

  • Immunohistochemical distribution of extracellular matrix proteins as a diagnostic parameter in healthy and diseased gingiva.

    abstract::This study showed histopathological findings of the extracellular matrix in healthy, inflamed, and hyperplastic human gingiva with immunohistochemical techniques. The distribution of collagen types V and VI, as well as of glycoprotein fibronectin, shows that they are extracellular matrix structural components which di...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1993.64.2.110

    authors: Romanos GE,Strub JR,Bernimoulin JP

    更新日期:1993-02-01 00:00:00

  • Mycoplasma in periodontal disease. Isolation in juvenile periodontitis.

    abstract::Mycoplasma have been identified in one case of juvenile periodontitis by size, morphology, hemadsorption and cultural techniques. These microorganisms were found on the surface of the tooth, on the surface of pocket epithelium and invading the gingival epithelium and adjacent connective tissue. These observations sugg...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1984.55.10.574

    authors: Newman MG,Saglie R,Carranza FA Jr,Kaufman AK

    更新日期:1984-10-01 00:00:00

  • The use of blade implants in a selected population of partially edentulous adults. A 15-year report.

    abstract::In order to provide longitudinal data for endosteal bladevent implants, a continuing study is being conducted from an original group of 49 implants in 32 patients placed 15 years ago. The present work evaluated 26 of these bladevent implants in 18 patients. Three basic patterns were observed 15 years postoperatively: ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1987.58.9.589

    authors: Smithloff M,Fritz ME

    更新日期:1987-09-01 00:00:00

  • Removal of an amalgam tattoo using a subepithelial connective tissue graft and laser deepithelialization.

    abstract:BACKGROUND:A 56-year-old female presented for periodontal treatment with a large amalgam tattoo located in alveolar mucosa on the facial aspect of her maxillary central incisors. The lesion had been present for 42 years since having endodontic surgery at teeth #8 and #9 after a traumatic childhood incident. METHODS:A ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2009.080613

    authors: Campbell CM,Deas DE

    更新日期:2009-05-01 00:00:00

  • Treatment of dehiscence-type defects with collagen matrix and/or enamel matrix derivative: Histomorphometric study in minipigs.

    abstract:BACKGROUND:This study aimed to evaluate, histomorphometrically, the use of collagen matrix (CM) and/or enamel matrix derivative (EMD) for the treatment of dehiscence-type recession defects in minipigs. METHODS:Eight healthy, male, young BR-1 minipigs, with no periodontal disease were treated. Bilateral dehiscence-type...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1002/JPER.19-0107

    authors: França-Grohmann IL,Sangiorgio JPM,Bueno MR,Casarin RCV,Silvério Ruiz KG,Nociti FH Jr,Casati MZ,Sallum EA

    更新日期:2020-07-01 00:00:00

  • A study of epithelial odontogenic residues in the pig.

    abstract::Formation of the junctional epithelium was studied by routine light microscopy in the molar teeth of commercially slaughtered pigs. It was found that the process whereby the reduced enamel epithelium (REE) contributed to the junctional epithelium formation corresponded largely with changes in man previously described ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1986.57.3.164

    authors: Spouge JD

    更新日期:1986-03-01 00:00:00

  • Special Feature: Journal of Periodontology 75th Anniversary.

    abstract::This is a posthumous interview with Dr. Maynard K. Hine (MKH), the second editor of the Journal of Periodontology (from 1950 to 1970), as prepared by Dr. David C. Vandersall (DCV). Dr. Vandersall was a colleague of Dr. Hine while serving as associate clinical professor of periodontics at the Indiana University School ...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2004.75.6.781

    authors:

    更新日期:2004-06-01 00:00:00

  • Risk assessment of lingual plate perforation in posterior mandibular region: a virtual implant placement study using cone-beam computed tomography.

    abstract:BACKGROUND:Lingual plate perforation at the time of implant placement in posterior mandible is a potential surgical complication, and presence of a lingual concavity is considered a risk factor. Little is known about the spatial relationship between implant and lingual plate. The role of lingual concavity in the risk o...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2010.100313

    authors: Chan HL,Benavides E,Yeh CY,Fu JH,Rudek IE,Wang HL

    更新日期:2011-01-01 00:00:00

  • An evaluation of laser Doppler readings obtained from human gingival sulci.

    abstract::A small laser doppler probe with an outside diameter comparable to a conventional periodontal probe (0.5 mm) was developed. The objectives of this investigation were to determine if intrasulcular laser doppler readings (LDR): 1) are reproducible; 2) can detect vascular changes associated with trauma from probe placeme...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章

    doi:10.1902/jop.1995.66.3.171

    authors: Hinrichs JE,LaBelle LL,Aeppli D

    更新日期:1995-03-01 00:00:00

  • Effects of marrow penetration on bone augmentation within a titanium cap in rabbit calvarium.

    abstract:BACKGROUND:Some studies have advocated marrow penetration in guided bone augmentation (GBA), whereas others have shown that bone can be generated without marrow penetration. This study examined the effect of marrow penetration and the optimal rate of penetration. METHODS:In 10 rabbits, the calvarium was exposed, and c...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2007.070086

    authors: Min S,Sato S,Murai M,Okuno K,Fujisaki Y,Yamada Y,Ito K

    更新日期:2007-10-01 00:00:00

  • Guided tissue regeneration with dentin biomodification.

    abstract::This study was undertaken to provide histologic observations on the effectiveness of citric acid and tetracycline HCl root surface demineralization when used in conjunction with guided tissue regeneration (GTR) procedures. Eight beagle dogs with naturally-occurring periodontitis were initially treated with scaling and...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.1993.64.11.1052

    authors: Dyer BL,Caffesse RG,Nasjleti CE,Morrison EC

    更新日期:1993-11-01 00:00:00

  • Underestimation of periodontitis in NHANES surveys.

    abstract::The study design of national surveys of periodontal disease often uses partial-mouth examination protocols to rationalize the need for resources so that the collection of data from a large number of subjects can be achieved within the available means without significantly sacrificing precision and validity. Studies sh...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2011.100638

    authors: Albandar JM

    更新日期:2011-03-01 00:00:00

  • Subgingival microflora in Turkish patients with periodontitis.

    abstract:BACKGROUND:No information exists on periodontitis-associated subgingival microbiota from Turkey. We determined the occurrence, interspecies relationships, and clonal characteristics for a group of periodontal bacteria in a Turkish study population. METHODS:Subgingival microbial samples were obtained from patients with...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2003.74.6.803

    authors: Doğan B,Antinheimo J,Cetiner D,Bodur A,Emingil G,Buduneli E,Uygur C,Firatli E,Lakio L,Asikainen S

    更新日期:2003-06-01 00:00:00

  • Validation of antibiotic efficacy on in vitro subgingival biofilms.

    abstract:BACKGROUND:Systemic antibiotics are often used as adjunctive treatment modalities for periodontal diseases. Testing of antimicrobial efficacy can be relevant only if the bacteria are in the form of biofilms rather than the planktonic state, and at concentrations of physiologic relevance, i.e., reachable in the periodon...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2013.130167

    authors: Belibasakis GN,Thurnheer T

    更新日期:2014-02-01 00:00:00

  • Citric acid demineralization and subepithelial connective tissue grafts.

    abstract:BACKGROUND:The present study was designed to evaluate the effect, if any, of citric acid root demineralization in the outcome of subepithelial connective tissue grafts performed to cover localized gingival recessions. METHODS:Thirty-six patients participated, each providing one gingival recession; 19 received citric a...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.2000.71.4.568

    authors: Caffesse RG,De LaRosa M,Garza M,Munne-Travers A,Mondragon JC,Weltman R

    更新日期:2000-04-01 00:00:00

  • Periodontal microcirculatory abnormalities in patients with systemic sclerosis.

    abstract:BACKGROUND:The aim of this study was to observe the differences in periodontal microcirculation between healthy patients and patients with systemic sclerosis (SSc). METHODS:Fifteen healthy patients and 15 patients with SSc were examined. Periodontal capillaroscopy was used to investigate the characteristics of microci...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2005.76.11.1991

    authors: Scardina GA,Pizzigatti ME,Messina P

    更新日期:2005-11-01 00:00:00

  • Radiographic methods for the detection of progressive alveolar bone loss.

    abstract::Intraoral transmission radiographs have been the primary diagnostic method for the assessment of bone support as well as for the detection and measurement of osseous changes due to periodontitis. The purpose of the present paper is three-fold. The first is to review radiographic techniques for the assessment of period...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.1992.63.4s.367

    authors: Jeffcoat MK

    更新日期:1992-04-01 00:00:00

  • Collinin reduces Porphyromonas gingivalis growth and collagenase activity and inhibits the lipopolysaccharide-induced macrophage inflammatory response and osteoclast differentiation and function.

    abstract:BACKGROUND:Collinin is a secondary plant metabolite belonging to the class of geranyloxycoumarins. We explored the potential beneficial impact of collinin on periodontal health by investigating its effect on Porphyromonas gingivalis (P. gingivalis), lipopolysaccharide (LPS)-induced inflammatory response of macrophages,...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2012.120118

    authors: Santos J,Marquis A,Epifano F,Genovese S,Curini M,Grenier D

    更新日期:2013-05-01 00:00:00

  • Periodontal soft tissue non-root coverage procedures: a systematic review from the AAP Regeneration Workshop.

    abstract:BACKGROUND:Gingival augmentation procedures around natural teeth and dental implants are performed to facilitate plaque control, to improve patient comfort, to prevent future recession, and in conjunction with restorative, orthodontic, or prosthetic dentistry. The aim of this study is to answer the most common question...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,评审

    doi:10.1902/jop.2015.130684

    authors: Kim DM,Neiva R

    更新日期:2015-02-01 00:00:00

  • Effect of Periodontal Therapy With Amoxicillin-Metronidazole on Pharyngeal Carriage of Penicillin- and Erythromycin-Resistant Viridans Streptococci.

    abstract:BACKGROUND:Previous studies have focused on antibiotic resistance of Gram-negative bacteria before and after periodontal therapy. The purpose of this analysis is to assess changes in resistance patterns of the commensal Gram-positive microbiota. The viridans group streptococci (VGS) have been suggested to serve as rese...

    journal_title:Journal of periodontology

    pub_type: 杂志文章,随机对照试验

    doi:10.1902/jop.2015.150494

    authors: Mombelli A,Cionca N,Almaghlouth A,Cherkaoui A,Schrenzel J,Giannopoulou C

    更新日期:2016-05-01 00:00:00

  • Preliminary Results of Non-Surgical Periodontal Treatment in Patients With Breast Cancer Undergoing Chemotherapy.

    abstract:BACKGROUND:Although priority is often given to treat the cancer itself, focus should also be directed to prevention and improvement of oral complications that may occur as a result of cancer and/or its treatment. This study compares periodontal treatment results in healthy patients and patients with breast cancer under...

    journal_title:Journal of periodontology

    pub_type: 杂志文章

    doi:10.1902/jop.2016.160101

    authors: Vargas-Villafuerte KR,Dantas FT,Messora MR,Novaes AB Jr,Grisi MF,Taba M Jr,Souza SL,Candido Dos Reis FJ,Carrara HH,Palioto DB

    更新日期:2016-11-01 00:00:00

  • The effect of an antimicrobial mouthrinse on early healing of gingival flap surgery wounds.

    abstract::A randomized double-blind crossover design study using 25 patients requiring bilateral gingival flap surgery was completed. The effect of rinsing postsurgically three times daily with an antimicrobial mouthrinse or physiological saline on dental plaque formation, gingival inflammation, bleeding, wound healing, and pat...

    journal_title:Journal of periodontology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1902/jop.1989.60.1.31

    authors: Zambon JJ,Ciancio SG,Mather ML,Charles CH

    更新日期:1989-01-01 00:00:00